PubHawk
Anesthesiology March 2017 PMID 28099246

Paradoxical Emergence: Administration of Subanesthetic Ketamine during Isoflurane Anesthesia Induces Burst Suppression but Accelerates Recovery.

Viviane S Hambrecht-Wiedbusch, Duan Li, George A Mashour

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Mentions

15
Peak: 1 in Feb 2017
across 4 sources since Feb 2017

Extended reach

6,709
potential audience

Total likes

46

Video views

6,024

Mentions per month

Feb 2017 – Sep 2021

Where it's discussed

  • Facebook11 posts
  • News2 articles
  • X / Twitter1 posts
  • YouTube1 videos

AI synopsis

What people are saying

Throughout the discussions, users show strong interest in the paradoxical nature of ketamine's effects, describing it as an 'anesthetic paradox' and noting the surprising acceleration in recovery despite deeper anesthesia. The tone combines curiosity and acknowledgment of potential clinical significance, such as comments about how these results could change anesthesia management or understanding of brain activity during sedation.

AgreementModerate agreement

Most discussions acknowledge the counterintuitive findings, showing moderate support for the results.

InterestHigh interest

Posts display high curiosity about the paradoxical effects and mechanisms involved in the study.

EngagementModerate engagement

Several posts explore detailed aspects of anesthesia and ketamine’s role, indicating active engagement.

ImpactModerate impact

Discussions suggest the findings could influence anesthesia practices and stimulate further research.

Abstract in brief

  • A single dose of subanesthetic ketamine during isoflurane anesthesia increases burst suppression in the brain but surprisingly speeds up recovery from anesthesia in rats.
  • Ketamine also significantly boosts acetylcholine release in the prefrontal cortex, which may help promote wakefulness and faster recovery.
  • Overall, the study suggests that while ketamine makes the brain appear more deeply anesthetized temporarily, it paradoxically helps rats regain consciousness more quickly, possibly by enhancing cortical cholinergic activity.]
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Top posts

Most liked on X and Bluesky
Damien
@ximtex · X

An anesthetic paradox: ketamine deepens anesthesia but accelerates recovery https://t.co/uBGojQ4Hy5 via @YouTube

Sep 16, 2021 · 685 followers View post →

All mentions

Damien
@ximtex · X

An anesthetic paradox: ketamine deepens anesthesia but accelerates recovery https://t.co/uBGojQ4Hy5 via @YouTube

Sep 16, 2021 · 685 followers View post →