The overall tone highlights curiosity and enthusiasm about Tadalafil's potential for muscle growth and vascular health, exemplified by posts asking 'Para que serve a tadalafila na musculação?' and comments describing its use as a 'pré-treino.' The humorous remarks and technical references reflect a mix of casual interest and some engagement with the scientific implications, contributing to a moderate overall impact perception.
AgreementModerate agreement
Most discussions acknowledge the positive effects of Tadalafil on muscle mass and endothelial function, indicating general agreement with the publication's findings.
InterestHigh interest
Many posters show high interest by questioning uses beyond the original scope and engaging with scientific details, reflecting curiosity about the drug's broader applications.
EngagementModerate engagement
Posts range from sharing personal reactions and humorous comments to discussing mechanisms, demonstrating moderate but meaningful engagement with the topic.
ImpactModerate impact
The discussions touch on potential uses for biohacking and muscle building, hinting at a perceived moderate impact on fitness and health communities.
Abstract in brief
Daily tadalafil intake led to increased abdominal lean mass and improved endothelial function in nonobese men with mild erectile or urinary symptoms, with some effects reversing after stopping the medication.
Tadalafil improved urinary and erectile symptoms (LUTS and ED scores), and its positive effects on endothelial health were linked to changes in insulin and estradiol hormone levels.
In lab studies, tadalafil increased androgen receptor and myogenin protein levels in skeletal muscle cells, suggesting it may promote muscle growth by enhancing hormone activity.
Here's the purported lean mass gain in this paper https://t.co/Ss1vJ9dDvq, which are:
32671 (baseline) g of lean 'trunk' with SE
34093 (2mo) g
33529 (2mo post) g
So (at face value) that's a net 'increase' in lean mass of 1422g,, followed by a 'loss' of 564g off the drug (i.e., https://t.co/YqdyBKglU1
Oct 3, 2024 · 7 likes · 56,108 followersView post →
BB
BowTiedOx | SOF Athlete/Bodybuilder
@BowTiedOx · X
@mtcodeslinger I’ll make it easier to start https://t.co/OrSWebbkuO
Oct 3, 2024 · 5 likes · 86,270 followersView post →
JP
Jorn Trommelen, PhD
@JornTrommelen · X
Study:
https://t.co/d09OnAa9W1
9/9
Did you find this useful? Please help promote the first tweet of the thread:
https://t.co/xx1iXpEClQ
May 15, 2023 · 5 likes · 2 shares · 7,628 followersView post →
N
NootBro
@nootropicguy · X
@NutriAlexandre https://t.co/x1JGe3tMmg
Mar 19, 2023 · 3 likes · 83,873 followersView post →
Daily tadalafil intake increased abdominal lean mass and improved endothelial function in men with mild erectile or urinary symptoms. It also enhanced urinary and erectile scores, potentially promoting muscle growth by…
Daily tadalafil intake increased abdominal lean mass and improved endothelial function in nonobese men with mild erectile or urinary symptoms, with some effects reversing after stopping the medication. It may promote…
Tadalafil improved lean mass and endothelial function in nonobese men with mild erectile or urinary symptoms, with effects related to hormonal changes. Laboratory studies suggest it may promote muscle growth by…
o que esse video tem de informativo, tem de engraçado XD XD XD
é por isso que eu amo esse canal XD XD XD
Para que serve a tadalafila na musculação? https://t.co/UmNHEKShZP via @YouTube
@mtcodeslinger I’ll make it easier to start https://t.co/OrSWebbkuO
Oct 3, 2024 · 5 likes · 86,270 followersView post →
SH
Stuart Phillips (he/him)
@mackinprof · X
Here's the purported lean mass gain in this paper https://t.co/Ss1vJ9dDvq, which are:
32671 (baseline) g of lean 'trunk' with SE
34093 (2mo) g
33529 (2mo post) g
So (at face value) that's a net 'increase' in lean mass of 1422g,, followed by a 'loss' of 564g off the drug (i.e., https://t.co/YqdyBKglU1
Oct 3, 2024 · 7 likes · 56,108 followersView post →
G
GDLeahy
@GDLeahy · X
"The in vitro increased myogenin and androgen receptor protein expression in skeletal muscle cells suggests a translational action of phosphodiesterase type-5 on this receptor." https://t.co/tSdXlEKkCG
RT @JornTrommelen: Study:
https://t.co/d09OnAa9W1
9/9
Did you find this useful? Please help promote the first tweet of the thread:
https:…
May 15, 2023 · 2 shares · 508 followersView post →
JA
Javed Alam
@jalam1001 · X
RT @JornTrommelen: Study:
https://t.co/d09OnAa9W1
9/9
Did you find this useful? Please help promote the first tweet of the thread:
https:…
May 15, 2023 · 2 shares · 1,006 followersView post →
JP
Jorn Trommelen, PhD
@JornTrommelen · X
Study:
https://t.co/d09OnAa9W1
9/9
Did you find this useful? Please help promote the first tweet of the thread:
https://t.co/xx1iXpEClQ
May 15, 2023 · 5 likes · 2 shares · 7,628 followersView post →
DP
Dr. Kirten Parekh
@KirtenParekh · X
Who knew d*ck pills could be used for biohacking:
"Daily tadalafil improved lean mass content in non-obese men probably via enhanced insulin secretion, estradiol reduction, and improvement of endothelial function in vivo"
https://t.co/C5iwlGuhnr