PLoS One August 2017 PMID 28166253

Effects of a very high saturated fat diet on LDL particles in adults with atherogenic dyslipidemia: A randomized controlled trial.

Sally Chiu, Paul T Williams, Ronald M Krauss

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Mentions

36
Peak: 3 in Dec 2023
across 4 sources since Jan 2019

Extended reach

247,430
potential audience

Total likes

214

Video views

10,209

Mentions per month

Jan 2019 – Feb 2025

Where it's discussed

  • X / Twitter15 posts
  • News10 articles
  • Facebook8 posts
  • YouTube3 videos

AI synopsis

What people are saying

The discussions reflect high interest and engagement, with examples like references to specific studies such as the publication by Krauss et al., and debates on how saturated fat impacts LDL particles, showing participants' intent to understand and interpret the research. The tone varies from analytical to dismissive, with some emphasizing potential health risks while others challenge conclusions or provide personal insights, demonstrating nuanced and active engagement with the article's findings.

AgreementNeither agree nor disagree

The discussions show a mix of support and skepticism towards the research, with some participants aligning their views and others questioning the findings.

InterestHigh interest

Participants are highly engaged in the topic, referencing related research, and discussing implications, indicating strong interest.

EngagementModerate engagement

Posts include references to scientific studies, technical details, and personal viewpoints, reflecting active and meaningful engagement.

ImpactModerate impact

The discussions could influence ongoing debates about saturated fats and cardiovascular health, but overall perceptions of the study's significance vary.

Abstract in brief

  • The study investigated how a very high saturated fat diet affects LDL particle sizes in adults with atherogenic dyslipidemia, finding that increased saturated fat intake led to significant rises in apolipoprotein B, medium, and small LDL particles, but not large LDL particles.
  • Participants consuming the high saturated fat diet experienced greater increases in total LDL particles, total cholesterol, and LDL cholesterol compared to those on a low saturated fat diet, indicating that saturated fat impacts various LDL subclasses differently in individuals with a specific lipid profile.
  • The findings suggest that in people with a predominance of small LDL particles (atherogenic dyslipidemia), high saturated fat intake can exacerbate levels of certain LDL subclasses, which may influence cardiovascular risk.]

Top posts

Most liked on X and Bluesky
Bryce Hanna
@photobiogenesis · X

This study looked at the effects of a high saturated fat diet on LDL particle size and found that while it had no effect on very large or very small particles, it did still increase small and medium particles https://t.co/AHOyv7NsON

Jan 6, 2022 · 9 likes · 34,095 followers View post →
Chirag Barjatya
@chiragbarjatyaa · X

Chiu, S., P.T. Williams, and R.M. Krauss, Effects of a very high saturated fat diet on LDL particles in adults with atherogenic dyslipidemia: A randomized controlled trial. PLOS ONE, 2017. 12(2): p. e0170664.

Mar 11, 2023 · 6 likes · 1 share · 99,017 followers View post →
Harmless Frog
@FrogHarmless · X

@MasalaFry69 @ScepticalDoctor Saturated fat compared to unsaturated fat appears to increase all classes of LDL. https://t.co/9LcuZ89r6O https://t.co/2kDcVJTsWy

Aug 2, 2022 · 5 likes · 502 followers View post →
Joel "Heart Prevention" Kahn MD, FACC
@drjkahn · X

Effects of a very high saturated fat diet on LDL particles in adults with atherogenic dyslipidemia: A randomized controlled trial. - PubMed - NCBI https://t.co/6HjzixOXhN

Jun 13, 2019 · 2 likes · 32,245 followers View post →
Alan Watson
@Alan_Watson_ · X

@kevinnbass @LDLSkeptic "Because medium & small LDL particles are more highly associated with cardiovascular disease than are larger LDL, the .. results suggest that very high saturated fat intake may increase cardiovascular disease risk in phenotype B individuals" Chiu DOI::10.1371/journal.pone.0170664 https://t.co/KwK7zFudHD

Jul 19, 2019 · 2 likes · 1,514 followers View post →
True Blood Net
@truebloodnet · X

@IamKristinBauer I'm sorry to disagree but milk has been associated with healthier LDL and lower risk. https://t.co/GbCw4TAGZA Also, some of us have little choice for medical reasons. I eat no mammal flesh, but can't give up eggs and milk and stay alive. So I buy from kindest sources I can find.

Jan 23, 2019 · 1 like · 46,316 followers View post →

All mentions

SPHdeORD
@SPHdeORD · X

@StevenMBelknap The strongest link in the fat causality chain is the association of High fat diets and elevated LDL cholesterol and elevated LDL and MI. I think you have some insights about that link. https://t.co/9H7zrpEFTQ

Dec 9, 2023 · 206 followers View post →
fvrmix
@fvrmix · X

@DrDrakeXrp @EarthlingAus @clayton_ulm @ChrisPalmerMD https://t.co/9ifGi9GAi5 There is so much chaotic science on LDL, in it there is an abundance that supports what I’m saying. And in the next few month there is more research coming about this effect in lean metabolic healthy people which should clear a lot up

Dec 1, 2023 · 51 followers View post →
fvrmix
@fvrmix · X

@Tellit007 @USNA_73 @Nutradvance https://t.co/9ifGi9GAi5 It’s almost very important to note it seems it depends on your body composition, there’s some good research getting released in the next few months on LMHRs

Dec 1, 2023 · 51 followers View post →
Kat Fu, M.S., M.S.
@thekatfu · X

Oct 5, 2023 · 1 like · 17,896 followers View post →
Santoor Daddy
@idcyar · X

RT @chiragbarjatyaa: Chiu, S., P.T. Williams, and R.M. Krauss, Effects of a very high saturated fat diet on LDL particles in adults with at…

Mar 11, 2023 · 1 share · 2,364 followers View post →
Chirag Barjatya
@chiragbarjatyaa · X

Chiu, S., P.T. Williams, and R.M. Krauss, Effects of a very high saturated fat diet on LDL particles in adults with atherogenic dyslipidemia: A randomized controlled trial. PLOS ONE, 2017. 12(2): p. e0170664.

Mar 11, 2023 · 6 likes · 1 share · 99,017 followers View post →
brand new soul ily quoy
@me_fafo · X

@henri_mourant @RomeoStevens76 @bananamelter @lillybilly299 @sunofdopamine @romeostevens Here's the distinction. Saturated fat doesn't seem to elevate VLDL or apoB in most people, which are usually the most pertinent variables in this discussion. However, some folks are more adversely affected by larger density LDL. https://t.co/eYa0IjLJDg

Feb 21, 2023 · 438 followers View post →
Harmless Frog
@FrogHarmless · X

@MasalaFry69 @ScepticalDoctor Saturated fat compared to unsaturated fat appears to increase all classes of LDL. https://t.co/9LcuZ89r6O https://t.co/2kDcVJTsWy

Aug 2, 2022 · 5 likes · 502 followers View post →
Das
@ssdas29 · X

@DiscoStew66 and its a #plos article https://t.co/BDfIqb3his

Jul 26, 2022 · 397 followers View post →
John Claude
@jclements27 · X

@gatorheartdoc @masksoff247 Yes - if we don't reduce carbohydrate, now you have two energy sources vying for cellular metabolism (Randle cycle). This leads to dyslipidemia, and it is not the fault of fat alone. This study : https://t.co/y5ofDdIwo3

Mar 29, 2022 · 211 followers View post →
Bryce Hanna
@photobiogenesis · X

This study looked at the effects of a high saturated fat diet on LDL particle size and found that while it had no effect on very large or very small particles, it did still increase small and medium particles https://t.co/AHOyv7NsON

Jan 6, 2022 · 9 likes · 34,095 followers View post →
ZahcM
@ZahcM · X

@LDLSkeptic Not LCHF - https://t.co/EUiWTw0UF7 https://t.co/4GoBtX3YWe

Jul 19, 2019 · 1,915 followers View post →
Alan Watson
@Alan_Watson_ · X

@kevinnbass @LDLSkeptic "Because medium & small LDL particles are more highly associated with cardiovascular disease than are larger LDL, the .. results suggest that very high saturated fat intake may increase cardiovascular disease risk in phenotype B individuals" Chiu DOI::10.1371/journal.pone.0170664 https://t.co/KwK7zFudHD

Jul 19, 2019 · 2 likes · 1,514 followers View post →
Joel "Heart Prevention" Kahn MD, FACC
@drjkahn · X

Effects of a very high saturated fat diet on LDL particles in adults with atherogenic dyslipidemia: A randomized controlled trial. - PubMed - NCBI https://t.co/6HjzixOXhN

Jun 13, 2019 · 2 likes · 32,245 followers View post →
True Blood Net
@truebloodnet · X

@IamKristinBauer I'm sorry to disagree but milk has been associated with healthier LDL and lower risk. https://t.co/GbCw4TAGZA Also, some of us have little choice for medical reasons. I eat no mammal flesh, but can't give up eggs and milk and stay alive. So I buy from kindest sources I can find.

Jan 23, 2019 · 1 like · 46,316 followers View post →