This study looked at the effects of a high saturated fat diet on LDL particle size and found that while it had no effect on very large or very small particles, it did still increase small and medium particles https://t.co/AHOyv7NsON
Effects of a very high saturated fat diet on LDL particles in adults with atherogenic dyslipidemia: A randomized controlled trial.
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Jan 2019 – Feb 2025Where it's discussed
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What people are saying
The discussions reflect high interest and engagement, with examples like references to specific studies such as the publication by Krauss et al., and debates on how saturated fat impacts LDL particles, showing participants' intent to understand and interpret the research. The tone varies from analytical to dismissive, with some emphasizing potential health risks while others challenge conclusions or provide personal insights, demonstrating nuanced and active engagement with the article's findings.
The discussions show a mix of support and skepticism towards the research, with some participants aligning their views and others questioning the findings.
Participants are highly engaged in the topic, referencing related research, and discussing implications, indicating strong interest.
Posts include references to scientific studies, technical details, and personal viewpoints, reflecting active and meaningful engagement.
The discussions could influence ongoing debates about saturated fats and cardiovascular health, but overall perceptions of the study's significance vary.
Abstract in brief
- The study investigated how a very high saturated fat diet affects LDL particle sizes in adults with atherogenic dyslipidemia, finding that increased saturated fat intake led to significant rises in apolipoprotein B, medium, and small LDL particles, but not large LDL particles.
- Participants consuming the high saturated fat diet experienced greater increases in total LDL particles, total cholesterol, and LDL cholesterol compared to those on a low saturated fat diet, indicating that saturated fat impacts various LDL subclasses differently in individuals with a specific lipid profile.
- The findings suggest that in people with a predominance of small LDL particles (atherogenic dyslipidemia), high saturated fat intake can exacerbate levels of certain LDL subclasses, which may influence cardiovascular risk.]
Top posts
Most liked on X and BlueskyChiu, S., P.T. Williams, and R.M. Krauss, Effects of a very high saturated fat diet on LDL particles in adults with atherogenic dyslipidemia: A randomized controlled trial. PLOS ONE, 2017. 12(2): p. e0170664.
@MasalaFry69 @ScepticalDoctor Saturated fat compared to unsaturated fat appears to increase all classes of LDL. https://t.co/9LcuZ89r6O https://t.co/2kDcVJTsWy
Effects of a very high saturated fat diet on LDL particles in adults with atherogenic dyslipidemia: A randomized controlled trial. - PubMed - NCBI https://t.co/6HjzixOXhN
@kevinnbass @LDLSkeptic "Because medium & small LDL particles are more highly associated with cardiovascular disease than are larger LDL, the .. results suggest that very high saturated fat intake may increase cardiovascular disease risk in phenotype B individuals" Chiu DOI::10.1371/journal.pone.0170664 https://t.co/KwK7zFudHD
@IamKristinBauer I'm sorry to disagree but milk has been associated with healthier LDL and lower risk. https://t.co/GbCw4TAGZA Also, some of us have little choice for medical reasons. I eat no mammal flesh, but can't give up eggs and milk and stay alive. So I buy from kindest sources I can find.
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@StevenMBelknap The strongest link in the fat causality chain is the association of High fat diets and elevated LDL cholesterol and elevated LDL and MI. I think you have some insights about that link. https://t.co/9H7zrpEFTQ
@DrDrakeXrp @EarthlingAus @clayton_ulm @ChrisPalmerMD https://t.co/9ifGi9GAi5 There is so much chaotic science on LDL, in it there is an abundance that supports what I’m saying. And in the next few month there is more research coming about this effect in lean metabolic healthy people which should clear a lot up
@Tellit007 @USNA_73 @Nutradvance https://t.co/9ifGi9GAi5 It’s almost very important to note it seems it depends on your body composition, there’s some good research getting released in the next few months on LMHRs
RT @chiragbarjatyaa: Chiu, S., P.T. Williams, and R.M. Krauss, Effects of a very high saturated fat diet on LDL particles in adults with at…
Chiu, S., P.T. Williams, and R.M. Krauss, Effects of a very high saturated fat diet on LDL particles in adults with atherogenic dyslipidemia: A randomized controlled trial. PLOS ONE, 2017. 12(2): p. e0170664.
@henri_mourant @RomeoStevens76 @bananamelter @lillybilly299 @sunofdopamine @romeostevens Here's the distinction. Saturated fat doesn't seem to elevate VLDL or apoB in most people, which are usually the most pertinent variables in this discussion. However, some folks are more adversely affected by larger density LDL. https://t.co/eYa0IjLJDg
@MasalaFry69 @ScepticalDoctor Saturated fat compared to unsaturated fat appears to increase all classes of LDL. https://t.co/9LcuZ89r6O https://t.co/2kDcVJTsWy
@DiscoStew66 and its a #plos article https://t.co/BDfIqb3his
@gatorheartdoc @masksoff247 Yes - if we don't reduce carbohydrate, now you have two energy sources vying for cellular metabolism (Randle cycle). This leads to dyslipidemia, and it is not the fault of fat alone. This study : https://t.co/y5ofDdIwo3
This study looked at the effects of a high saturated fat diet on LDL particle size and found that while it had no effect on very large or very small particles, it did still increase small and medium particles https://t.co/AHOyv7NsON
@LDLSkeptic Not LCHF - https://t.co/EUiWTw0UF7 https://t.co/4GoBtX3YWe
@kevinnbass @LDLSkeptic "Because medium & small LDL particles are more highly associated with cardiovascular disease than are larger LDL, the .. results suggest that very high saturated fat intake may increase cardiovascular disease risk in phenotype B individuals" Chiu DOI::10.1371/journal.pone.0170664 https://t.co/KwK7zFudHD
Effects of a very high saturated fat diet on LDL particles in adults with atherogenic dyslipidemia: A randomized controlled trial. - PubMed - NCBI https://t.co/6HjzixOXhN
@IamKristinBauer I'm sorry to disagree but milk has been associated with healthier LDL and lower risk. https://t.co/GbCw4TAGZA Also, some of us have little choice for medical reasons. I eat no mammal flesh, but can't give up eggs and milk and stay alive. So I buy from kindest sources I can find.
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