This is in line with other works that suggested that the vocal tract and cerebellum went through particularly extensive regulatory changes in modern humans, e.g.,: https://t.co/v2QGfEDfJe https://t.co/S8Dl00E3EI https://t.co/OUaZ1eMBR7 https://t.co/HlzL2gh5FS
Impacts of Neanderthal-Introgressed Sequences on the Landscape of Human Gene Expression.
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Apr 2021 – Aug 2025Where it's discussed
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AI synopsis
What people are saying
Discussions show moderate engagement, with comments referencing related studies, such as differences in brain and vocal tract evolution, highlighting the gene regulation impacts of Neanderthal sequences; the tone remains analytical and curious, reflecting moderate interest.
Most discussions acknowledge the significance of regulatory changes in gene expression influenced by Neanderthal DNA, showing moderate consensus.
Participants display a mild interest, focusing on specific aspects like noncoding regions and brain-related changes without deep exploration.
Comments refer to related research and expand on the article's findings, indicating some engagement but not deep debate.
The conversations suggest recognition of scientific importance, but don't emphasize immediate or transformative implications.
Abstract in brief
- The study explores how Neanderthal DNA sequences that are inherited in modern humans influence gene expression, highlighting their widespread impact on regulatory variation.
- Using a Bayesian method to analyze RNA data, the researchers found significant differences in gene expression between Neanderthal and modern human alleles, especially noting downregulation in brain and testes tissues.
- The findings suggest that these Neanderthal sequences are actively shaping phenotypic diversity in humans through their regulatory effects, indicating natural selection has influenced their retention.]
Top posts
Most liked on X and Bluesky@emethias @FondOfBeetles Oh like how we have mostly noncoding regions? Good point! I am finding research supporting gene expression impacting the immune system and brain. Can’t find estimates for noncoding, nonregulatory proportions. I’d assume this is similar for all admixture. https://t.co/APAnHT4dEc
RT @David_Gokhman: This is in line with other works that suggested that the vocal tract and cerebellum went through particularly extensive…
RT @David_Gokhman: This is in line with other works that suggested that the vocal tract and cerebellum went through particularly extensive…
All mentions
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CRISPR Epigenome Editing and Its Therapeutic Potential
In this episode of Frontiers of Research, experts discuss how CRISPR technology is being adapted to modify epigenetic marks without altering DNA, opening new avenues for understanding gene regulation and treating…
@emethias @FondOfBeetles Oh like how we have mostly noncoding regions? Good point! I am finding research supporting gene expression impacting the immune system and brain. Can’t find estimates for noncoding, nonregulatory proportions. I’d assume this is similar for all admixture. https://t.co/APAnHT4dEc
RT @David_Gokhman: This is in line with other works that suggested that the vocal tract and cerebellum went through particularly extensive…
RT @David_Gokhman: This is in line with other works that suggested that the vocal tract and cerebellum went through particularly extensive…
RT @David_Gokhman: This is in line with other works that suggested that the vocal tract and cerebellum went through particularly extensive…
This is in line with other works that suggested that the vocal tract and cerebellum went through particularly extensive regulatory changes in modern humans, e.g.,: https://t.co/v2QGfEDfJe https://t.co/S8Dl00E3EI https://t.co/OUaZ1eMBR7 https://t.co/HlzL2gh5FS
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