February 2017 PMID 28235201

Impacts of Neanderthal-Introgressed Sequences on the Landscape of Human Gene Expression.

Rajiv C McCoy, Jon Wakefield, Joshua M Akey

Mentions

68
Peak: 4 in Apr 2021
across 5 sources since Apr 2021

Extended reach

21,047
potential audience

Total likes

15

Video views

3

Mentions per month

Apr 2021 – Aug 2025

Where it's discussed

  • News45 articles
  • Facebook10 posts
  • Blogs6 articles
  • X / Twitter5 posts
  • YouTube2 videos

AI synopsis

What people are saying

Discussions show moderate engagement, with comments referencing related studies, such as differences in brain and vocal tract evolution, highlighting the gene regulation impacts of Neanderthal sequences; the tone remains analytical and curious, reflecting moderate interest.

AgreementModerate agreement

Most discussions acknowledge the significance of regulatory changes in gene expression influenced by Neanderthal DNA, showing moderate consensus.

InterestModerate interest

Participants display a mild interest, focusing on specific aspects like noncoding regions and brain-related changes without deep exploration.

EngagementModerate engagement

Comments refer to related research and expand on the article's findings, indicating some engagement but not deep debate.

ImpactNeutral impact

The conversations suggest recognition of scientific importance, but don't emphasize immediate or transformative implications.

Abstract in brief

  • The study explores how Neanderthal DNA sequences that are inherited in modern humans influence gene expression, highlighting their widespread impact on regulatory variation.
  • Using a Bayesian method to analyze RNA data, the researchers found significant differences in gene expression between Neanderthal and modern human alleles, especially noting downregulation in brain and testes tissues.
  • The findings suggest that these Neanderthal sequences are actively shaping phenotypic diversity in humans through their regulatory effects, indicating natural selection has influenced their retention.]

Top posts

Most liked on X and Bluesky
David Gokhman
@David_Gokhman · X

This is in line with other works that suggested that the vocal tract and cerebellum went through particularly extensive regulatory changes in modern humans, e.g.,: https://t.co/v2QGfEDfJe https://t.co/S8Dl00E3EI https://t.co/OUaZ1eMBR7 https://t.co/HlzL2gh5FS

Apr 22, 2021 · 14 likes · 3 shares · 1,237 followers View post →
Joam Buttock
@JxnW · X

@emethias @FondOfBeetles Oh like how we have mostly noncoding regions? Good point! I am finding research supporting gene expression impacting the immune system and brain. Can’t find estimates for noncoding, nonregulatory proportions. I’d assume this is similar for all admixture. https://t.co/APAnHT4dEc

Sep 12, 2022 · 1 like · 620 followers View post →
Dmitri Petrov
@PetrovADmitri · X

RT @David_Gokhman: This is in line with other works that suggested that the vocal tract and cerebellum went through particularly extensive…

Apr 22, 2021 · 3 shares · 14,520 followers View post →
Judyth Mermelstein☮️
@GadflyQuebec · X

RT @David_Gokhman: This is in line with other works that suggested that the vocal tract and cerebellum went through particularly extensive…

Apr 23, 2021 · 3 shares · 3,641 followers View post →

All mentions

Joam Buttock
@JxnW · X

@emethias @FondOfBeetles Oh like how we have mostly noncoding regions? Good point! I am finding research supporting gene expression impacting the immune system and brain. Can’t find estimates for noncoding, nonregulatory proportions. I’d assume this is similar for all admixture. https://t.co/APAnHT4dEc

Sep 12, 2022 · 1 like · 620 followers View post →
Judyth Mermelstein☮️
@GadflyQuebec · X

RT @David_Gokhman: This is in line with other works that suggested that the vocal tract and cerebellum went through particularly extensive…

Apr 23, 2021 · 3 shares · 3,641 followers View post →
Peter Davidson
@petedavo_au · X

RT @David_Gokhman: This is in line with other works that suggested that the vocal tract and cerebellum went through particularly extensive…

Apr 23, 2021 · 3 shares · 1,003 followers View post →
Dmitri Petrov
@PetrovADmitri · X

RT @David_Gokhman: This is in line with other works that suggested that the vocal tract and cerebellum went through particularly extensive…

Apr 22, 2021 · 3 shares · 14,520 followers View post →
David Gokhman
@David_Gokhman · X

This is in line with other works that suggested that the vocal tract and cerebellum went through particularly extensive regulatory changes in modern humans, e.g.,: https://t.co/v2QGfEDfJe https://t.co/S8Dl00E3EI https://t.co/OUaZ1eMBR7 https://t.co/HlzL2gh5FS

Apr 22, 2021 · 14 likes · 3 shares · 1,237 followers View post →