March 2017 PMID 28273480

Enhanced Protein Translation Underlies Improved Metabolic and Physical Adaptations to Different Exercise Training Modes in Young and Old Humans.

Matthew M Robinson, Surendra Dasari, Adam R Konopka, Matthew L Johnson, S Manjunatha, Raul Ruiz Esponda, Rickey E Carter, Ian R Lanza, K Sreekumaran Nair

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Mentions

408

Peak: 10 in Apr 2021

across 7 sources since Aug 2019

Extended reach

330,120

potential audience

Total likes

1,863

Video views

155,967

Mentions per month

Aug 2019 – Sep 2025

Where it's discussed

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AI synopsis

What people are saying

Examples from these discussions include references to how HIIT can reverse age-related decline in mitochondrial function and improve metabolic health, with phrases like 'boosts aerobic capacity' and 'reverses many age-related consequences' illustrating enthusiasm and recognition of potential benefits. The tone varies from scientific curiosity to motivational appeals, emphasizing the relevance of the research for healthy aging and physical performance.

AgreementModerate agreement

Most discussions acknowledge the validity of the study, with many endorsing the positive effects of exercise modes like HIIT on aging and metabolism, as seen in comments highlighting mitochondrial improvements and metabolic benefits.

InterestHigh interest

Users demonstrate strong curiosity about the research, frequently mentioning specific terms like 'mitochondria,' 'protein translation,' and 'exercise modes,' indicating active engagement with the technical content.

EngagementHigh engagement

Several discussions refer to detailed findings such as mitochondrial function, gene expression, and implications for aging, showing deep curiosity and consideration of the broader significance of the research.

ImpactModerate impact

People generally perceive the study as impactful, with some discussions framing it as a potential tool for anti-aging and health improvements, although most emphasize the scientific insights more than immediate real-world implications.

Abstract in brief

The study found that different exercise modes like high-intensity interval training (HIIT), resistance training (RT), and combined workouts improve metabolic health and muscle mass, with HIIT and combined training also boosting aerobic capacity and mitochondrial function especially in older adults.
HIIT leads to significant gene expression changes and restores age-related differences in mitochondrial proteins, mainly by increasing protein synthesis, even though only slight DNA methylation changes were observed.
All exercise types enhance the cellular machinery for protein production (translational machinery), which helps increase muscle and mitochondrial function, explaining the physical and metabolic benefits seen across different age groups.

Read the full abstract

All mentions

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Lucho

@luchoh.bsky.social · Bluesky

Enhanced Protein Translation Underlies Improved Metabolic and Physical Adaptations to Different Exercise Training Modes in Young and Old Humans: Cell Metabolism www.cell.com/cell-metabol...

Sep 27, 2025 View post →

JOE(ジョー)

@joe_wolf_howl · X

⭕ノルウェイ式HIIT(バーピー4分間×4set)をこなす ※半年ぶりに再開 https://t.co/uOLgSaR00T https://t.co/SnTLSIrbnG

Jan 27, 2025 · 1 like · 159 followers View post →

Jamie Timmons

@metapredict · X

@StephenORahilly @DUK_research Masterful loss of 70% samples; presentation of intervention when unpaired samples? https://t.co/ohwVQEy98p Or masterful use of low quality RNAseq to create a story that RNA & Protein aren’t coordinated? https://t.co/04ueNBVkcu Easily demonstrated as wrong https://t.co/y1BXdJMOwo

Apr 19, 2024 · 2,053 followers View post →

tokatti

@tokatti_ · X

HIITには損傷したタンパク質の蓄積を防ぐ効果があるよう週3でHIITをやることで細胞内のサビが取れて新しいタンパク質に生まれ変わるそう週に3〜4回のHIITを行い、これに2日の筋トレをプラスできれば最高とのこと https://t.co/5dhCBGCGh3 #自分用メモ

Dec 10, 2022 · 179 followers View post →

Nick Krontiris

@nick_krontiris · X

Sep 29, 2022 · 2 likes · 18,978 followers View post →

Erhan Tenekecioğlu

@drercardio · X

RT @drercardio: Egzersizi ihmal etmeyelim

Sep 17, 2022 · 6 shares · 65,665 followers View post →

Şiir - Humaniste

@NihalPia_zen · X

RT @drercardio: Egzersizi ihmal etmeyelim

Sep 16, 2022 · 6 shares · 2,146 followers View post →

aylin

@___aylin_ · X

RT @drercardio: Egzersizi ihmal etmeyelim

Sep 16, 2022 · 6 shares · 1,522 followers View post →

Alparslan

@muh_alparslan · X

RT @drercardio: Egzersizi ihmal etmeyelim

Sep 16, 2022 · 6 shares · 800 followers View post →

ekmel eratan

@ekmel_eratan · X

RT @drercardio: Egzersizi ihmal etmeyelim

Sep 16, 2022 · 6 shares · 161 followers View post →

Erhan Tenekecioğlu

@drercardio · X

Egzersizi ihmal etmeyelim

Sep 16, 2022 · 60 likes · 6 shares · 65,665 followers View post →

@cesar050855 · X