Neuron March 2017 PMID 28285819

Imaging ERK and PKA Activation in Single Dendritic Spines during Structural Plasticity.

Shen Tang, Ryohei Yasuda

Mentions

6
Peak: 3 in Aug 2021
across 2 sources since Mar 2017

Extended reach

7,686
potential audience

Total likes

31

Video views

2,954

Mentions per month

Mar 2017 – Sep 2021

Where it's discussed

  • X / Twitter5 posts
  • YouTube1 videos

AI synopsis

What people are saying

The discussions highlight appreciation for the paper's emphasis on reproducibility and open science principles, with comments like 'We appreciate the author's support of reproducibility,' which demonstrate supportive and somewhat technical engagement. The tone is positive and focused on scientific rigor, reflecting moderate interest and perceived impact in promoting transparent research practices.

AgreementModerate agreement

Most discussions praise the publication for supporting reproducibility, showing general agreement with its scientific value.

InterestModerate interest

Participants show moderate interest, primarily focused on the methodological aspects like RRIDs and open science practices.

EngagementModerate engagement

Comments reflect a decent level of engagement by emphasizing reproducibility and the importance of transparency in research.

ImpactModerate impact

The collective tone suggests the publication encourages better practices and could influence future research, indicating moderate impact.

Abstract in brief

  • This study enhanced FRET-based sensors to better detect ERK and PKA kinase activities in tiny parts of neurons, called dendritic spines, using advanced imaging techniques.
  • The improved sensors allowed researchers to observe how ERK and PKA activate and spread during long-term potentiation (LTP), a process involved in learning and memory, revealing that their activation can extend more than 10 micrometers within the neuron.
  • The methods developed for increasing sensor sensitivity could be used to create better biosensors for other protein kinases, helping scientists study various cellular signaling processes more precisely.]

Top posts

Most liked on X and Bluesky
OpenSci Talk
@OpenSciTalk · X

RT @RobotRrid: The authors of "untitled" (https://t.co/l0k4fiEYSp) included RRIDs in their paper! RRIDs like this improve reproducibility i…

Aug 13, 2021 · 1 share · 4,085 followers View post →
RRID Robot
@RobotRrid · X

The authors of "Imaging ERK and PKA Activation in Single Dendritic…" (https://t.co/l0k4fiEYSp) included RRIDs in their paper! We appreciate the author's support of reproducibility. #OpenScience #STMpublishing

Sep 6, 2021 · 161 followers View post →
RRID Robot
@RobotRrid · X

The authors of "Imaging ERK and PKA Activation in Single Dendritic…" (https://t.co/l0k4fiEYSp) included RRIDs in their paper! We appreciate the author's support of reproducibility. #accelerateopenscience #OpenScience

Sep 1, 2021 · 161 followers View post →
RRID Robot
@RobotRrid · X

The authors of "untitled" (https://t.co/l0k4fiEYSp) included RRIDs in their paper! RRIDs like this improve reproducibility in scientific research. #RRID #OpenScience

Aug 13, 2021 · 1 share · 161 followers View post →

All mentions

RRID Robot
@RobotRrid · X

The authors of "Imaging ERK and PKA Activation in Single Dendritic…" (https://t.co/l0k4fiEYSp) included RRIDs in their paper! We appreciate the author's support of reproducibility. #OpenScience #STMpublishing

Sep 6, 2021 · 161 followers View post →
RRID Robot
@RobotRrid · X

The authors of "Imaging ERK and PKA Activation in Single Dendritic…" (https://t.co/l0k4fiEYSp) included RRIDs in their paper! We appreciate the author's support of reproducibility. #accelerateopenscience #OpenScience

Sep 1, 2021 · 161 followers View post →
OpenSci Talk
@OpenSciTalk · X

RT @RobotRrid: The authors of "untitled" (https://t.co/l0k4fiEYSp) included RRIDs in their paper! RRIDs like this improve reproducibility i…

Aug 13, 2021 · 1 share · 4,085 followers View post →
RRID Robot
@RobotRrid · X

The authors of "untitled" (https://t.co/l0k4fiEYSp) included RRIDs in their paper! RRIDs like this improve reproducibility in scientific research. #RRID #OpenScience

Aug 13, 2021 · 1 share · 161 followers View post →
RRID Robot
@RobotRrid · X

The authors of "Imaging ERK and PKA Activation in Single Dendritic…" (https://t.co/l0k4fiEYSp) included RRIDs in their paper! We appreciate the author's support of reproducibility. #OpenScience #RRID

Aug 1, 2021 · 161 followers View post →