June 2017 PMID 28397310

Creatine supplementation reduces sleep need and homeostatic sleep pressure in rats.

Markus Dworak, Tae Kim, Robert W Mccarley, Radhika Basheer

Mentions

70
Peak: 23 in Jan 2021
across 7 sources since Jan 2021

Extended reach

419,795
potential audience

Total likes

349

Video views

2,459

Mentions per month

Jan 2021 – Dec 2025

Where it's discussed

  • X / Twitter38 posts
  • Reddit18 posts
  • TikTok4 posts
  • Facebook3 posts
  • News3 articles
  • YouTube2 videos
  • Instagram2 posts

AI synopsis

What people are saying

Overall, the discussions reflect strong agreement with the study’s implications, especially through phrases like 'potential in treatment' and 'interesting and novel research,' while curiosity about real-world applications and underlying biochemistry shows high interest, moderating between superficial and deep engagement. The tone ranges from speculative to supportive, highlighting the potential significance of creatine's effects on sleep and brain energy metabolism.

AgreementModerate agreement

Most discussions support the idea that creatine reduces sleep need, with users referencing biochemical evidence and potential applications.

InterestHigh interest

Posts show high curiosity, especially with mentions of applications for sleep disorders, mental performance, and gamers.

EngagementModerate engagement

Participants engage by sharing personal interpretations, potential research translation to humans, and related biochemical insights.

ImpactModerate impact

The discussions suggest a moderate potential impact on health, mental performance, and sleep management, though mostly based on animal research.

Abstract in brief

  • Creatine supplementation in rats reduces total sleep time and non-REM sleep, especially during their inactive light period, suggesting it decreases sleep need.
  • Biochemical analysis shows an increase in phosphocreatine and a decrease in ATP levels in the brain after creatine intake, implying altered energy metabolism.
  • Microdialysis results indicate that creatine attenuates the sleep deprivation-induced increase in extracellular adenosine, which is associated with sleep pressure, further suggesting creatine's role in reducing sleep homeostasis.]

Top posts

Most liked on X and Bluesky
Master Metabolism
@lowmegatron · X

“Creatine supplementation reduces sleep need and homeostatic sleep pressure in rats, thereby indicating its potential in the treatment of sleep-related disorders.” https://t.co/tMvWABGLM7 https://t.co/qWr0geqrkG

Feb 20, 2025 · 209 likes · 13 shares · 32,557 followers View post →
JT | Jerry Teixeira
@jerryteixeira · X

Creatine isn’t just for muscles, It’s also brain food! It may be especially helpful During times of low sleep as it may reduce sleep need & it’s an ideal supplement for plant based folks as it’s dietarily found only in animal foods (Animal study) https://t.co/0VxcTPbLlO

Feb 18, 2021 · 94 likes · 12 shares · 79,369 followers View post →
Brady Holmer
@Brady_H · X

@CoachRydman This study was literally why I started taking creatine (before having our first kid—proactively). https://t.co/3OSGxRkTVV Creatine-supplementation reduces sleep need and homeostatic sleep pressure in rats - PMC

Aug 1, 2025 · 5 likes · 27,208 followers View post →
bioMioSoftware
@bioMioSoftware · X

"⬇️total sleep time/NREM..during the light (inactive) but not during the dark (active) period. NREM sleep..⬇️..after 6 h of sleep deprivation.. sleep deprivation‐induced ⬆️ in extracellular adenosine was attenuated after CS" @nick_krontiris @shivadas29 https://t.co/KiGmR7Rilk

Jan 15, 2021 · 5 likes · 3 shares · 102 followers View post →
P ⏩ 2XKO! Home Owning! Hamster Posting!
@p_channnLIFTS · X

@Drdannypham Also interesting and fairly novel research, it's suggested that creatine may reduce sleep need. Interesting for gamers/esports! https://t.co/lkXBlSi7JM

Jan 21, 2021 · 3 likes · 2,589 followers View post →
_nonfigurativ_
@_nonfigurativ_ · X

@treeve There seems to be some scientific evidence to support this https://t.co/xyGGbB4frB

Aug 22, 2023 · 1 like · 50,700 followers View post →

All mentions

Brady Holmer
@Brady_H · X

@CoachRydman This study was literally why I started taking creatine (before having our first kid—proactively). https://t.co/3OSGxRkTVV Creatine-supplementation reduces sleep need and homeostatic sleep pressure in rats - PMC

Aug 1, 2025 · 5 likes · 27,208 followers View post →
Collector
@desiresimulacra · X

RT @lowmegatron: “Creatine supplementation reduces sleep need and homeostatic sleep pressure in rats, thereby indicating its potential in t…

May 11, 2025 · 13 shares · 256 followers View post →
diemitdemkrisenstabheult
@WinterFreeda1 · X

RT @P1231032850: 8/PubMed https://t.co/dRFQjv51zb

May 4, 2025 · 1 share · 3,513 followers View post →
P123
@P1231032850 · X

8/PubMed https://t.co/dRFQjv51zb

May 4, 2025 · 1 share · 3,408 followers View post →
Snyder
@nobodyM33 · X

RT @lowmegatron: “Creatine supplementation reduces sleep need and homeostatic sleep pressure in rats, thereby indicating its potential in t…

Feb 21, 2025 · 13 shares · 458 followers View post →
MichaelT7474
@Michael49992359 · X

RT @lowmegatron: “Creatine supplementation reduces sleep need and homeostatic sleep pressure in rats, thereby indicating its potential in t…

Feb 21, 2025 · 13 shares · 2,269 followers View post →
Laura Lou
@freedomranger70 · X

RT @lowmegatron: “Creatine supplementation reduces sleep need and homeostatic sleep pressure in rats, thereby indicating its potential in t…

Feb 20, 2025 · 13 shares · 448 followers View post →
JD Culper Jr
@jd_culperjr · X

RT @lowmegatron: “Creatine supplementation reduces sleep need and homeostatic sleep pressure in rats, thereby indicating its potential in t…

Feb 20, 2025 · 13 shares · 2,109 followers View post →
distorted70
@distorted70 · X

RT @lowmegatron: “Creatine supplementation reduces sleep need and homeostatic sleep pressure in rats, thereby indicating its potential in t…

Feb 20, 2025 · 13 shares · 558 followers View post →
Ryn.
@rynmolina · X

RT @lowmegatron: “Creatine supplementation reduces sleep need and homeostatic sleep pressure in rats, thereby indicating its potential in t…

Feb 20, 2025 · 13 shares · 411 followers View post →
つとむ
@tsutomuinfinity · X

RT @lowmegatron: “Creatine supplementation reduces sleep need and homeostatic sleep pressure in rats, thereby indicating its potential in t…

Feb 20, 2025 · 13 shares · 188 followers View post →
klamka
@pustaera · X

RT @lowmegatron: “Creatine supplementation reduces sleep need and homeostatic sleep pressure in rats, thereby indicating its potential in t…

Feb 20, 2025 · 13 shares · 522 followers View post →
Master Metabolism
@lowmegatron · X

“Creatine supplementation reduces sleep need and homeostatic sleep pressure in rats, thereby indicating its potential in the treatment of sleep-related disorders.” https://t.co/tMvWABGLM7 https://t.co/qWr0geqrkG

Feb 20, 2025 · 209 likes · 13 shares · 32,557 followers View post →
Roundlay
@roundlay · X

@tapir_worf Urge to experiment with creating and sleep data increasing. No idea if this study translates to humans, but finding that adenosine levels decreased after taking creatine is a good sign that creatine/sleep association is plausible in humans: https://t.co/YStTHybxhy

Dec 11, 2023 · 1 like · 114 followers View post →
Mike
@MikeSumms · X

@parafactual https://t.co/1w7qT0RpID Also creatine may reduce how much sleep your mind requires

Sep 20, 2023 · 55 followers View post →
_nonfigurativ_
@_nonfigurativ_ · X

@treeve There seems to be some scientific evidence to support this https://t.co/xyGGbB4frB

Aug 22, 2023 · 1 like · 50,700 followers View post →
Philip Larsson
@Philip97larsson · X

Dags att bli super-human! "Creatine-supplementation reduces sleep need and homeostatic sleep pressure in rats" https://t.co/DQdFk6BgwD

Aug 28, 2022 · 46 followers View post →
P ⏩ 2XKO! Home Owning! Hamster Posting!
@p_channnLIFTS · X

@DrJordantsai https://t.co/Df10wBKqZV. More articles and research now I'm sure but this was a paper I read!

May 26, 2022 · 1 like · 2,589 followers View post →
J Sam
@JaicSam · X

https://t.co/3xXLyXL2ss https://t.co/43HLIVVPg5

Nov 30, 2021 · 1 like · 982 followers View post →
Greg Grandgeorge
@T2MCoach · X

Creatine supplementation reduces sleep need and homeostatic sleep pressure in rats - Dworak - 2017 - Journal of Sleep Research - Wiley Online Library https://t.co/NCn7xdMpaC

Jun 29, 2021 · 259 followers View post →
Paul Hough
@the_hough · X

Creatine supplementation reduces sleep need and homeostatic sleep pressure in

Jun 14, 2021 · 1 like · 1,999 followers View post →
coffee
@ketohacking · X

RT @jerryteixeira: Creatine isn’t just for muscles, It’s also brain food! It may be especially helpful During times of low sleep as it ma…

Feb 19, 2021 · 12 shares · 64 followers View post →
Adam Ibrahim, PhD, CSCS, CISSN
@thecoachai · X

RT @jerryteixeira: Creatine isn’t just for muscles, It’s also brain food! It may be especially helpful During times of low sleep as it ma…

Feb 19, 2021 · 12 shares · 293 followers View post →
L ❤ V E
@drkohilathas · X

RT @jerryteixeira: Creatine isn’t just for muscles, It’s also brain food! It may be especially helpful During times of low sleep as it ma…

Feb 19, 2021 · 12 shares · 47,919 followers View post →
SmartNutrition
@SmartNutrition1 · X

RT @jerryteixeira: Creatine isn’t just for muscles, It’s also brain food! It may be especially helpful During times of low sleep as it ma…

Feb 18, 2021 · 12 shares · 2,642 followers View post →
Kuro Midori
@5thRing · X

RT @jerryteixeira: Creatine isn’t just for muscles, It’s also brain food! It may be especially helpful During times of low sleep as it ma…

Feb 18, 2021 · 12 shares · 151 followers View post →
Ale
@Alepedernera23 · X

RT @jerryteixeira: Creatine isn’t just for muscles, It’s also brain food! It may be especially helpful During times of low sleep as it ma…

Feb 18, 2021 · 12 shares · 295 followers View post →
Leonardo Rocha
@Leo_Fit · X

RT @jerryteixeira: Creatine isn’t just for muscles, It’s also brain food! It may be especially helpful During times of low sleep as it ma…

Feb 18, 2021 · 12 shares · 89,036 followers View post →
GMeeshelle
@GMeeshelle · X

RT @jerryteixeira: Creatine isn’t just for muscles, It’s also brain food! It may be especially helpful During times of low sleep as it ma…

Feb 18, 2021 · 12 shares · 1,119 followers View post →
Furious Styles
@kingF0X23 · X

RT @jerryteixeira: Creatine isn’t just for muscles, It’s also brain food! It may be especially helpful During times of low sleep as it ma…

Feb 18, 2021 · 12 shares · 876 followers View post →
Brady Holmer
@Brady_H · X

RT @jerryteixeira: Creatine isn’t just for muscles, It’s also brain food! It may be especially helpful During times of low sleep as it ma…

Feb 18, 2021 · 12 shares · 27,208 followers View post →
Michael Padula HPA.Coach
@MJPadula · X

RT @jerryteixeira: Creatine isn’t just for muscles, It’s also brain food! It may be especially helpful During times of low sleep as it ma…

Feb 18, 2021 · 12 shares · 5,620 followers View post →
JT | Jerry Teixeira
@jerryteixeira · X

Creatine isn’t just for muscles, It’s also brain food! It may be especially helpful During times of low sleep as it may reduce sleep need & it’s an ideal supplement for plant based folks as it’s dietarily found only in animal foods (Animal study) https://t.co/0VxcTPbLlO

Feb 18, 2021 · 94 likes · 12 shares · 79,369 followers View post →
P ⏩ 2XKO! Home Owning! Hamster Posting!
@p_channnLIFTS · X

@Drdannypham Also interesting and fairly novel research, it's suggested that creatine may reduce sleep need. Interesting for gamers/esports! https://t.co/lkXBlSi7JM

Jan 21, 2021 · 3 likes · 2,589 followers View post →
Best Health 4 You
@besthealthyou · X

RT @bioMioSoftware: "⬇️total sleep time/NREM..during the light (inactive) but not during the dark (active) period. NREM sleep..⬇️..after 6…

Jan 16, 2021 · 3 shares · 512 followers View post →
J P Fanton
@HealthyFellow · X

RT @bioMioSoftware: "⬇️total sleep time/NREM..during the light (inactive) but not during the dark (active) period. NREM sleep..⬇️..after 6…

Jan 16, 2021 · 3 shares · 25,995 followers View post →
wendylee
@wendylee21742 · X

RT @bioMioSoftware: "⬇️total sleep time/NREM..during the light (inactive) but not during the dark (active) period. NREM sleep..⬇️..after 6…

Jan 15, 2021 · 3 shares · 2,022 followers View post →
bioMioSoftware
@bioMioSoftware · X

"⬇️total sleep time/NREM..during the light (inactive) but not during the dark (active) period. NREM sleep..⬇️..after 6 h of sleep deprivation.. sleep deprivation‐induced ⬆️ in extracellular adenosine was attenuated after CS" @nick_krontiris @shivadas29 https://t.co/KiGmR7Rilk

Jan 15, 2021 · 5 likes · 3 shares · 102 followers View post →
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... após a perda de sono. Referenciando este estudo: https://onlinelibrary.wiley.com/doi/full/10.1111/jsr.12523. [apagado]. • há 5 anos.

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Less deep sleep with creatine : r/Nootropics
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... REM sleep after sleep loss. Referencing this study: https://onlinelibrary.wiley.com/doi/full/10.1111/jsr.12523. [deleted]. • 5y ago.

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... -Schlaf nach Schlafentzug. Bezugnehmend auf diese Studie: https://onlinelibrary.wiley.com/doi/full/10.1111/jsr.12523. Upvoten 2. Downvoten

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... az alváshiány után. Hivatkozva erre a tanulmányra: https://onlinelibrary.wiley.com/doi/full/10.1111/jsr.12523. [törölve]. • 5 évvel ezelőtt.

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... REM sâu hơn sau khi bị mất ngủ. Tham khảo nghiên cứu này: https://onlinelibrary.wiley.com/doi/full/10.1111/jsr.12523. [đã xóa]. • 5 năm trước.

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... 睡眠(非REM睡眠)减少,并且非REM睡眠的强度也降低了。 引用这项研究:. https://onlinelibrary.wiley.com/doi/full/10.1111/jsr.12523. [已删除]. • 5年前.

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... privazione del sonno. Facendo riferimento a questo studio: https://onlinelibrary.wiley.com/doi/full/10.1111/jsr.12523. [eliminato]. • 5 anni fa.

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... intens după privarea de somn. Referencing this study: https://onlinelibrary.wiley.com/doi/full/10.1111/jsr.12523. [șters]. • acum 5 ani.

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... 睡眠の強度が低下しました。 参照している研究:. https://onlinelibrary.wiley.com/doi/full/10.1111/jsr.12523. [削除されました]. • 5 年前.

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