Andrology July 2017 PMID 28453908

Sexual dysfunction in subjects treated with inhibitors of 5α-reductase for benign prostatic hyperplasia: a comprehensive review and meta-analysis.

G Corona, G Tirabassi, D Santi, E Maseroli, M Gacci, M Dicuio, A Sforza, E Mannucci, M Maggi

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Mentions

27
Peak: 1 in Feb 2023
across 4 sources since Feb 2023

Extended reach

6,396
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Total likes

173

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Feb 2023 – Jul 2024

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AI synopsis

What people are saying

Discussions reflect strong agreement with the article by highlighting the data showing a 50% increased risk of decreased libido and erectile dysfunction, emphasizing the importance of these findings. The tone and choice of words, such as 'over-risk' and detailed statistical references, convey a sense of urgency and recognition of the study's significance in influencing medical decisions.

AgreementStrong agreement

All discussions acknowledge the meta-analysis's findings, emphasizing the increased risks of sexual dysfunction linked to 5ARIs, which shows consensus with the publication.

InterestHigh interest

The posts demonstrate high interest, as they cite detailed data such as odds ratios and numbers of studies, reflecting a focus on the research's implications.

EngagementModerate engagement

While most posts engage deeply by referencing specific statistics and the significance of the findings, some simply restate the risks without elaborating further.

ImpactHigh impact

The serious tone and mention of increased risks, along with the potential influence on treatment choices, indicate that these discussions recognize the publication's notable impact.

Abstract in brief

  • The study reviews randomized clinical trials and finds that treatment with 5-reductase inhibitors (5ARIs) like finasteride and dutasteride for benign prostatic hyperplasia significantly raises the risk of sexual side effects, specifically decreased sexual desire and erectile dysfunction.
  • The increased risk is consistent regardless of the specific drug used or patient factors such as age, prostate size, or symptom severity; however, the likelihood of sexual side effects is higher in patients with lower initial sexual function scores and tends to decrease with longer treatment duration.
  • Overall, the findings suggest that while 5ARIs are effective for benign prostatic hyperplasia, their use is limited by the potential for sexual dysfunction, which should be considered when evaluating treatment options.]

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Lans Alexandre
@LansAlexandre · X

@HerntzK @axeldob @Fildrong https://t.co/r0EqKU1D4x Une méta-analyse qui compile les données de 17 études et 24 000 patient. Elle retrouve un sur-risque (Odds-ratios) de 50% de diminution de la libido et de dyfonction érectile. Ou celle la qui retrouve un sur-risque similaire https://t.co/Fc3RqI4ncK

Jul 21, 2024 · 2 followers View post →

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Lans Alexandre
@LansAlexandre · X

@HerntzK @axeldob @Fildrong https://t.co/r0EqKU1D4x Une méta-analyse qui compile les données de 17 études et 24 000 patient. Elle retrouve un sur-risque (Odds-ratios) de 50% de diminution de la libido et de dyfonction érectile. Ou celle la qui retrouve un sur-risque similaire https://t.co/Fc3RqI4ncK

Jul 21, 2024 · 2 followers View post →
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