July 2017 PMID 28459931

Effect of Alternate-Day Fasting on Weight Loss, Weight Maintenance, and Cardioprotection Among Metabolically Healthy Obese Adults: A Randomized Clinical Trial.

John F Trepanowski, Cynthia M Kroeger, Adrienne Barnosky, Monica C Klempel, Surabhi Bhutani, Kristin K Hoddy, Kelsey Gabel, Sally Freels, Joseph Rigdon, Jennifer Rood, Eric Ravussin, Krista A Varady

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Mentions

494
Peak: 9 in Jun 2021
across 6 sources since Oct 2018

Extended reach

509,041
potential audience

Total likes

3,389

Video views

296,454

Mentions per month

Oct 2018 – Oct 2025

Where it's discussed

  • News335 articles
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  • YouTube6 videos
  • Reddit4 posts

AI synopsis

What people are saying

The overall tone reflects cautious acknowledgment that alternate-day fasting may not be superior to simple calorie restriction, with comments like 'It doesn’t work' and references to multiple studies. Posts cite examples such as the lack of differences in weight loss and adherence, emphasizing that evidence points to similar outcomes, with words and tone conveying moderate interest and engagement about the relevance and implications of these results.

AgreementNeither agree nor disagree

Most discussions point out that the study finds no significant advantage of alternate-day fasting over daily caloric restriction, reflecting a neutral stance overall.

InterestModerate interest

Participants show moderate curiosity, with some posts expressing disappointment or skepticism about fasting's effectiveness, but few exploration details.

EngagementModerate engagement

Many comments reference specific studies, compare findings, and mention broader implications, indicating a moderate level of engagement.

ImpactModerate impact

The discussions suggest the findings influence opinions about dieting strategies, but there's no strong consensus on a major paradigm shift yet.

Abstract in brief

  • The study compared alternate-day fasting, daily calorie restriction, and no intervention over one year in obese adults to evaluate effects on weight loss, maintenance, and cardiovascular risk indicators, with results showing similar weight loss in both fasting and calorie restriction groups.
  • Participants in the alternate-day fasting group tended to eat more than the recommended calories on fasting days and less on feast days, while those in the daily calorie restriction group mostly stayed within their calorie goals.
  • The dropout rate was highest in the alternate-day fasting group, and overall, both fasting and calorie restriction were effective for weight loss, but adherence to prescribed calories varied between groups.]

Top posts

Most liked on X and Bluesky
Jorn Trommelen, PhD
@JornTrommelen · X

Alternate day fasting is not superior for weight loss compared to daily caloric restriction when calories are matched. Full breakdown: https://t.co/nLpmfcZWox Study: https://t.co/anSfbiIS3a #weightloss #dieting #fasting https://t.co/oby1qlhXeL

Jun 5, 2021 · 28 likes · 6 shares · 7,615 followers View post →
Fabian Klumpp
@medizinfreiburg · X

(11/11) die vizepräsidentin der deutschen gesellschaft für ernährungsmedizin prof. Bosy-Westphal erklärte, dass auch der langfristige erfolg sich in keiner weise unterschied. ‼️ https://t.co/kf1xhjUgIp

Oct 16, 2022 · 16 likes · 3,143 followers View post →
Stuart Phillips (he/him)
@mackinprof · X

@BioLayne @CakeNutrition @vanvlietphd @_PaulMorgan @DrMyohead @Nicholas_Burd @OllyWitard @BenjaminTWall @LeighBreen @JornTrommelen https://t.co/SoKcU3XzEw Alternate-day fasting did not produce superior adherence, weight loss, weight maintenance, or cardioprotection vs daily calorie restriction.

Jun 6, 2021 · 5 likes · 55,905 followers View post →
Profe Claudio Nieto
@profeclaudioni1 · X

"El ayuno en días alternos no produjo una adherencia, pérdida de peso, mantenimiento de peso o cardioprotección superiores frente a la restricción calórica diaria" https://t.co/ciN429CQpV

Nov 27, 2020 · 3 likes · 13,975 followers View post →
Bárbara Romano
@reequilibra · X

@arbelo_e @hospitalclinic Citan artículo "effect of alternate-day fasting on weight loss, weight maintenance and cardioprotector among metabolically healthy obese adults" dónde no ven diferencias entre ambos métodos por lo que parece que tampoco servirían todos los tipos de ayuno o, leído de otra forma:

Jan 1, 2020 · 3 likes · 888 followers View post →
Dietitians Webinar
@WbDietitians · X

يشرح لنا الان الاستاذ رائد نتائج هذه الدراسة Effect of Alternate-Day Fasting on Weight Loss, Weight Maintenance, and Cardioprotection Among Metabolically Healthy Obese Adults: A Randomized Clinical Trial: https://t.co/VwuJel8rne

Feb 28, 2021 · 2 likes · 1 share · 7,592 followers View post →

All mentions

誘引剤は食品添加物、香料なので安心! ダニよせゲットシート10枚組
@A2urna · X

@fG7BdqIRJ22ijhV Effect of alternate-day fasting on weight loss, weight maintenance, and cardioprotection Calorie restriction and cardiometabolic health

Apr 1, 2025 · 57 followers View post →
タバコの煙にコロナが付着
@25kgzj · X

@fG7BdqIRJ22ijhV Effect of alternate-day fasting on weight loss, weight maintenance, and cardioprotection Calorie restriction and cardiometabolic health

Apr 1, 2025 · 58 followers View post →
Jake Mey, PhD, RD
@CakeNutrition · X

@BioLayne But one of their earlier reports targeted cardiometabolic health JAMA pub: https://t.co/e6GJ0wA87v

Oct 20, 2024 · 8,657 followers View post →
णणड्ठ - 周沫辰
@sitdh · X

ฟังจากหมอแล้วเริ่มหาข้อมูลเพิ่ม doi:10.1001/jamainternmed.2017.0936 https://t.co/G7MgeL2stY

Jun 27, 2024 · 1,885 followers View post →
Hob Gadling
@OliveChirper · X

@mkaeberlein @robertlufkinmd As you (@mkaeberlein) have also pointed out,the dog study result is also associational.Larger,longer-term human clinical trials find TRE yields few to no benefits vs. similar overall daily calorie control https://t.co/tH2uWMtdUt https://t.co/8tWC9B4fVF https://t.co/Kd5h5xfwLW

Jun 28, 2023 · 1 like · 275 followers View post →
Hob Gadling
@OliveChirper · X

@LaraPo8 @mkaeberlein A number of human studies find that time-restricted feeding leads disproportionately to loss of lean vs. adipose tissue — eg, probably most rigorously, https://t.co/tH2uWMtdUt Tho' surprisingly not in this largeish alternate-day fasting trial https://t.co/MCTfMElluZ

Dec 4, 2022 · 1 like · 275 followers View post →
Fabian Klumpp
@medizinfreiburg · X

(11/11) die vizepräsidentin der deutschen gesellschaft für ernährungsmedizin prof. Bosy-Westphal erklärte, dass auch der langfristige erfolg sich in keiner weise unterschied. ‼️ https://t.co/kf1xhjUgIp

Oct 16, 2022 · 16 likes · 3,143 followers View post →
Chirag Barjatya
@chiragbarjatyaa · X

@ThatKarbiGuy @SandeepMall https://t.co/kfTRevfbqg

Oct 17, 2021 · 96,585 followers View post →
Jake Mey, PhD, RD
@CakeNutrition · X

1) nutritional geometry https://t.co/AgCck6fdom 2) methionine restriction https://t.co/f7AiAKv1Mw 3) the fasting mimicking diet https://t.co/H0Moe90Wc9 4) alternate day fasting https://t.co/e6GJ0wiwIV

Jun 7, 2021 · 8,657 followers View post →
Weldon
@Rocker75W · X

RT @JornTrommelen: Alternate day fasting is not superior for weight loss compared to daily caloric restriction when calories are matched.…

Jun 6, 2021 · 6 shares · 330 followers View post →
Stuart Phillips (he/him)
@mackinprof · X

@BioLayne @CakeNutrition @vanvlietphd @_PaulMorgan @DrMyohead @Nicholas_Burd @OllyWitard @BenjaminTWall @LeighBreen @JornTrommelen https://t.co/SoKcU3XzEw Alternate-day fasting did not produce superior adherence, weight loss, weight maintenance, or cardioprotection vs daily calorie restriction.

Jun 6, 2021 · 5 likes · 55,905 followers View post →
paulo alvarez
@rpaulotovar · X

RT @JornTrommelen: Alternate day fasting is not superior for weight loss compared to daily caloric restriction when calories are matched.…

Jun 6, 2021 · 6 shares · 440 followers View post →
Nutricionistajuanquintero
@NutricionistaJQ · X

RT @JornTrommelen: Alternate day fasting is not superior for weight loss compared to daily caloric restriction when calories are matched.…

Jun 5, 2021 · 6 shares · 41 followers View post →
NFFC
@Kingofcreatine · X

RT @JornTrommelen: Alternate day fasting is not superior for weight loss compared to daily caloric restriction when calories are matched.…

Jun 5, 2021 · 6 shares · 62 followers View post →
Alma Morgendorffer
@Morgendorffiano · X

RT @JornTrommelen: Alternate day fasting is not superior for weight loss compared to daily caloric restriction when calories are matched.…

Jun 5, 2021 · 6 shares · 89 followers View post →
Omar Hammouda
@HammoudaOm · X

RT @JornTrommelen: Alternate day fasting is not superior for weight loss compared to daily caloric restriction when calories are matched.…

Jun 5, 2021 · 6 shares · 807 followers View post →
Jorn Trommelen, PhD
@JornTrommelen · X

Alternate day fasting is not superior for weight loss compared to daily caloric restriction when calories are matched. Full breakdown: https://t.co/nLpmfcZWox Study: https://t.co/anSfbiIS3a #weightloss #dieting #fasting https://t.co/oby1qlhXeL

Jun 5, 2021 · 28 likes · 6 shares · 7,615 followers View post →
Dietitians Webinar
@WbDietitians · X

يشرح لنا الان الاستاذ رائد نتائج هذه الدراسة Effect of Alternate-Day Fasting on Weight Loss, Weight Maintenance, and Cardioprotection Among Metabolically Healthy Obese Adults: A Randomized Clinical Trial: https://t.co/VwuJel8rne

Feb 28, 2021 · 2 likes · 1 share · 7,592 followers View post →
Profe Claudio Nieto
@profeclaudioni1 · X

"El ayuno en días alternos no produjo una adherencia, pérdida de peso, mantenimiento de peso o cardioprotección superiores frente a la restricción calórica diaria" https://t.co/ciN429CQpV

Nov 27, 2020 · 3 likes · 13,975 followers View post →
Samuele Graffiedi
@irongrafFT · X

Nessuna differenza a un anno di perdita di peso, mantenimento o cardioprotezione tra “digiunare” un giorno si e uno no e una restrizione calorica moderata (75% kcal) giornaliera (cioè a parità di calorie) https://t.co/FklULSQRO8 https://t.co/rsMcReQcgo

Apr 22, 2020 · 1 like · 1,071 followers View post →
Barb; Grandmother
@Gramma_Barbie · X

Effect of Alternate-Day Fasting on Weight Loss, Weight Maintenance, and Cardioprotection Among Metabolically Healthy Obese Adults: A Randomized Clinical Trial tldr: It doesn’t work. Damn. I have GOT to get this weight off! https://t.co/yYfmX1xBvj

Mar 29, 2020 · 891 followers View post →
Bárbara Romano
@reequilibra · X

@arbelo_e @hospitalclinic Citan artículo "effect of alternate-day fasting on weight loss, weight maintenance and cardioprotector among metabolically healthy obese adults" dónde no ven diferencias entre ambos métodos por lo que parece que tampoco servirían todos los tipos de ayuno o, leído de otra forma:

Jan 1, 2020 · 3 likes · 888 followers View post →
Hob Gadling
@OliveChirper · X

@kevinnbass Do you include alternate-day fasting? https://t.co/MCTfMECowZ

Sep 29, 2019 · 275 followers View post →
Andrés Suárez Glez.
@serdna975 · X

@PepitoGrilloBHB @AntiguoAthlon @nutrifriki @FITrebelde @juanjo235929 @IsmaelGalancho @Sergio_Espinar @Eldharan @AlexGayo @megustastarbien @AlexTR @Supertramp027 @PrimalCefe @nu_TRIceci @mitokondriac @Keto_fan @DiegoNSalman @EstebanDL @JulioBasulto_DN No escasean los "sádicos" diseñando ayuno intermitente con dieta alta en carbohidratos, como en Trepanowski et alter (2017) con 55% https://t.co/DVd9BmyXHs o Antoni et alter (2017) con 250g https://t.co/cxPEs4wnsQ No he mirado el resto (estarán en tabla 2) https://t.co/QB1GfAJogI

Sep 11, 2019 · 1 like · 2,929 followers View post →