Neuron May 2017 PMID 28472659

Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins.

Lulu Y Chen, Man Jiang, Bo Zhang, Ozgun Gokce, Thomas C Südhof

Mentions

23
Peak: 5 in Sep 2021
across 4 sources since Jul 2021

Extended reach

4,958
potential audience

Total likes

3

Video views

9

Mentions per month

Jul 2021 – Feb 2025

Where it's discussed

  • X / Twitter15 posts
  • YouTube3 videos
  • News3 articles
  • Blogs2 articles

AI synopsis

What people are saying

The overall discussions highlight the value of reproducibility, with many posts praising the inclusion of RRIDs and practices that improve scientific transparency, using positive and supportive language that indicates moderate engagement and acknowledgment of the publication's contributions.

AgreementModerate agreement

Most discussions recognize the importance of the research, especially emphasizing transparency and reproducibility, indicating general agreement with the findings and methods.

InterestModerate interest

Posts demonstrate a moderate level of curiosity, mostly focusing on details like RRIDs and reproducibility rather than deeper scientific implications.

EngagementNeutral engagement

Many comments remark on the inclusion of RRIDs and reproducibility practices but do not delve into the biological significance or broader impact.

ImpactModerate impact

Acknowledgment of the importance of reproducibility tools suggests some impact on scientific rigor, though not a direct focus on the article's scientific findings.

Abstract in brief

  • Neurexins are crucial synaptic organizers whose functions vary depending on the specific synapse, acting as context-dependent specifiers rather than universal building blocks.
  • Experiments with mice lacking all neurexins showed that different types of synapses in the brain—such as those in the cerebellum and prefrontal cortex—exhibit diverse and significant impairments when neurexins are absent.
  • These findings suggest that neurexins do not serve a single, universal role at all synapses but instead tailor synaptic properties based on the specific neural context.

Top posts

Most liked on X and Bluesky
Daniel A. Walker
@danwalker9999 · X

@MicrobiomDigest @PubPeer Original article, with links to high-res versions of figures https://t.co/lIUnTzCo0t Supplemental figures are here, but without high-res versions https://t.co/Qw3wbLQIJm

Jul 21, 2024 · 3 likes · 1 share · 1,773 followers View post →
Abstream
@abstreamme · X

Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins #science #publication #research #publications https://t.co/Btzrz7UUpj

May 17, 2024 · 785 followers View post →
Life Science Journal Content
@lsn_jc · X

Retraction Notice to: Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins #science #publication #research #journal https://t.co/8kifNUMauo

Feb 13, 2025 · 260 followers View post →
Life Science Journal Content
@lsn_jc · X

Retraction Notice to: Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins #science #publication #research #journal https://t.co/5ffmtrWBaa

Feb 12, 2025 · 260 followers View post →
Life Science Journal Content
@lsn_jc · X

Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins #science #publication #research #journal https://t.co/Zoxo5WUSEi

May 21, 2024 · 260 followers View post →
RRID Robot
@RobotRrid · X

RRIDs were included in the Neuron paper "Conditional Deletion of All Neurexins Defines Dive…" (https://t.co/VMJcWYRvHV). Thank you for making your #methodsmatter. #accelerateopenscience

Aug 14, 2021 · 161 followers View post →

All mentions

Life Science Journal Content
@lsn_jc · X

Retraction Notice to: Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins #science #publication #research #journal https://t.co/8kifNUMauo

Feb 13, 2025 · 260 followers View post →
Life Science Journal Content
@lsn_jc · X

Retraction Notice to: Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins #science #publication #research #journal https://t.co/5ffmtrWBaa

Feb 12, 2025 · 260 followers View post →
Daniel A. Walker
@danwalker9999 · X

@MicrobiomDigest @PubPeer Original article, with links to high-res versions of figures https://t.co/lIUnTzCo0t Supplemental figures are here, but without high-res versions https://t.co/Qw3wbLQIJm

Jul 21, 2024 · 3 likes · 1 share · 1,773 followers View post →
Life Science Journal Content
@lsn_jc · X

Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins #science #publication #research #journal https://t.co/Zoxo5WUSEi

May 21, 2024 · 260 followers View post →
Abstream
@abstreamme · X

Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins #science #publication #research #publications https://t.co/Btzrz7UUpj

May 17, 2024 · 785 followers View post →
RRID Robot
@RobotRrid · X

The authors of "Conditional Deletion of All Neurexins Defines Dive…" (https://t.co/VMJcWYRvHV) included RRIDs in their paper! We appreciate the author's support of reproducibility. #RRID #accelerateopenscience

Sep 6, 2021 · 161 followers View post →
RRID Robot
@RobotRrid · X

The authors of "Conditional Deletion of All Neurexins Defines Dive…" (https://t.co/VMJcWYRvHV) included RRIDs in their paper! We appreciate the author's support of reproducibility. #methodsmatter #RRID

Sep 4, 2021 · 161 followers View post →
RRID Robot
@RobotRrid · X

The authors of "Conditional Deletion of All Neurexins Defines Dive…" (https://t.co/VMJcWYRvHV) included RRIDs in their paper! RRIDs like this improve reproducibility in scientific research. #STMpublishing #methodsmatter

Sep 4, 2021 · 161 followers View post →
RRID Robot
@RobotRrid · X

RRIDs were included in the Neuron paper "Conditional Deletion of All Neurexins Defines Dive…" (https://t.co/VMJcWYRvHV). We appreciate the author's support of reproducibility. #methodsmatter #STMpublishing

Sep 3, 2021 · 161 followers View post →
RRID Robot
@RobotRrid · X

The authors of "Conditional Deletion of All Neurexins Defines Dive…" (https://t.co/VMJcWYRvHV) included RRIDs in their paper! RRIDs like this improve reproducibility in scientific research. #methodsmatter #accelerateopenscience

Sep 3, 2021 · 161 followers View post →
RRID Robot
@RobotRrid · X

The authors of "Conditional Deletion of All Neurexins Defines Dive…" (https://t.co/VMJcWYRvHV) included RRIDs in their paper! Thank you for making your #methodsmatter. #reproducibility

Aug 29, 2021 · 161 followers View post →
RRID Robot
@RobotRrid · X

RRIDs were included in the Neuron paper "Conditional Deletion of All Neurexins Defines Dive…" (https://t.co/VMJcWYRvHV). RRIDs like this improve reproducibility in scientific research. #methodsmatter #reproducibility

Aug 27, 2021 · 161 followers View post →
RRID Robot
@RobotRrid · X

The authors of "Conditional Deletion of All Neurexins Defines Dive…" (https://t.co/VMJcWYRvHV) included RRIDs in their paper! RRIDs like this improve reproducibility in scientific research. #reproducibility #RRID

Aug 21, 2021 · 161 followers View post →
RRID Robot
@RobotRrid · X

RRIDs were included in the Neuron paper "Conditional Deletion of All Neurexins Defines Dive…" (https://t.co/VMJcWYRvHV). Thank you for making your #methodsmatter. #accelerateopenscience

Aug 14, 2021 · 161 followers View post →
RRID Robot
@RobotRrid · X

RRIDs were included in the Neuron paper "Conditional Deletion of All Neurexins Defines Dive…" (https://t.co/VMJcWYRvHV). Thank you for making your #methodsmatter. #STMpublishing

Jul 28, 2021 · 161 followers View post →