Nat Med July 2017 PMID 28530702

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug.

Hao Wu, Eduardo Esteve, Valentina Tremaroli, Muhammad Tanweer Khan, Robert Caesar, Louise Mannerås-Holm, Marcus Ståhlman, Lisa M Olsson, Matteo Serino, Mercè Planas-Fèlix, Gemma Xifra, Josep M Mercader, David Torrents, Rémy Burcelin, Wifredo Ricart

Mentions

112
Peak: 4 in Sep 2025
across 5 sources since Apr 2019

Extended reach

79,611
potential audience

Total likes

23

Video views

1,194

Mentions per month

Apr 2019 – Sep 2025

Where it's discussed

  • Facebook58 posts
  • News27 articles
  • X / Twitter14 posts
  • Blogs10 articles
  • YouTube3 videos

AI synopsis

What people are saying

The discussions reflect a general recognition of the study's relevance, with phrases like 'here's a second study' and references to the 'therapeutic effects' emphasizing ongoing interest and validation. Words like 'contributing to' and tagging of experts suggest a tone of curiosity and acknowledgment of potential significance, indicating a balanced moderate engagement with an awareness of the study's possible impact.

AgreementModerate agreement

Most social discussions acknowledge the significance of the study, with many referencing multiple studies and expressing interest in the findings.

InterestModerate interest

The discussions show moderate interest, with repeated mentions of the study and related research, indicating engagement but not deep debate.

EngagementModerate engagement

Users reference additional research and tag relevant experts, demonstrating some level of detailed engagement and curiosity.

ImpactModerate impact

The conversations imply recognition of the potential importance of the findings for diabetes treatment and microbiome research, though without strong assertions of paradigm shifts.

Abstract in brief

  • Metformin, a common medication for type 2 diabetes, significantly changes the gut microbiome, which contributes to its therapeutic effects.
  • A study showed that individuals taking metformin had notable shifts in their gut bacteria, and transferring these bacteria to germ-free mice improved the mice’s glucose tolerance.
  • Researchers found that metformin influences specific bacterial pathways related to metal transport, suggesting that alterations in gut microbiota partly explain how the drug helps manage diabetes.

Top posts

Most liked on X and Bluesky
Amy Proal, PhD
@microbeminded2 · X

Here’s a 2nd study on the topic

May 9, 2019 · 8 likes · 2 shares · 29,356 followers View post →
Woody Nist
@Woodynist · X

1/2 Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug @philippefroguel @CHUAmiens @IHU_Marseille @raoult_didier @Pr_Chabriere_E @BlancFrdric7 https://t.co/pSyGd8lkKl

Apr 4, 2024 · 3 likes · 1 share · 1,311 followers View post →
Aubrai
@Aubrai_ · X

@AshleyW62906095 @BioProtocol

Sep 17, 2025 · 1 like · 10,796 followers View post →
Charles Quarry
@CharlesQuarry · X

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug. https://t.co/XAZxztAvw9

Apr 15, 2019 · 1 like · 443 followers View post →
Aubrai
@Aubrai_ · X

@FofofofShf @BioProtocol

Sep 17, 2025 · 10,796 followers View post →
Aubrai
@Aubrai_ · X

@Stephan57826096 @BioProtocol

Sep 17, 2025 · 10,796 followers View post →

All mentions

Aubrai
@Aubrai_ · X

@FofofofShf @BioProtocol

Sep 17, 2025 · 10,796 followers View post →
Aubrai
@Aubrai_ · X

@Stephan57826096 @BioProtocol

Sep 17, 2025 · 10,796 followers View post →
Aubrai
@Aubrai_ · X

@ahadmfgggg451 @BioProtocol

Sep 17, 2025 · 10,796 followers View post →
Aubrai
@Aubrai_ · X

@AshleyW62906095 @BioProtocol

Sep 17, 2025 · 1 like · 10,796 followers View post →
Diana
@PharmphoodTM · X

RT @Woodynist: 1/2 Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeuti…

Apr 4, 2024 · 1 share · 556 followers View post →
Woody Nist
@Woodynist · X

1/2 Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug @philippefroguel @CHUAmiens @IHU_Marseille @raoult_didier @Pr_Chabriere_E @BlancFrdric7 https://t.co/pSyGd8lkKl

Apr 4, 2024 · 3 likes · 1 share · 1,311 followers View post →
Isatou Sarr
@IsatouSarr4 · X

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therap… https://t.co/vSZBTYQwxq

Sep 17, 2021 · 33 followers View post →
カズン@走れる管理栄養士
@sahakazu · X

https://t.co/7bMVnICm1F

May 10, 2021 · 627 followers View post →
マナ@産業保健師
@mana_hok · X

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therap… https://t.co/89fdL7NkIu

Mar 18, 2021 · 57 followers View post →
hataboSAN
@hataboSAN · X

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug https://t.co/t1Auyu6BbJ

Aug 13, 2020 · 994 followers View post →
World Of Microbiome
@WorldMicrobiome · X

RT @microbeminded2: Here’s a 2nd study on the topic

May 10, 2019 · 2 shares · 19 followers View post →
Park View Project
@Parkviewprojec5 · X

RT @microbeminded2: Here’s a 2nd study on the topic

May 10, 2019 · 2 shares · 1,822 followers View post →
Amy Proal, PhD
@microbeminded2 · X

Here’s a 2nd study on the topic

May 9, 2019 · 8 likes · 2 shares · 29,356 followers View post →
Charles Quarry
@CharlesQuarry · X

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug. https://t.co/XAZxztAvw9

Apr 15, 2019 · 1 like · 443 followers View post →