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Ann Rheum Dis September 2017 PMID 28533290

Pharmaceutical-grade Chondroitin sulfate is as effective as celecoxib and superior to placebo in symptomatic knee osteoarthritis: the ChONdroitin versus CElecoxib versus Placebo Trial (CONCEPT).

Jean-Yves Reginster, Jean Dudler, Tomasz Blicharski, Karel Pavelka

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Mentions

25
Peak: 2 in Nov 2019
across 5 sources since May 2017

Extended reach

53,765
potential audience

Total likes

528

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51,767

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May 2017 – Apr 2025

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AI synopsis

What people are saying

The discussions reflect a neutral to slightly positive stance, with mentions of past studies, such as Professor Jean-Yves Reginster’s research, and questions about glucosamine, highlighting an interest in treatment options. The tone is modest, with some users referencing the article and related research but without extensive debate or critique.

AgreementModerate agreement

Most discussions express support or recognition of the study's results, indicating general agreement on its findings.

InterestModerate interest

Posts show moderate curiosity, referencing related treatments like glucosamine and past research, but not deeply exploring implications.

EngagementModerate engagement

Participants briefly discuss the content, such as mentioning the paper or related topics, but do not delve into detailed analysis.

ImpactModerate impact

There is a sense that the publication could influence treatment choices, though the discussions are mainly surface-level and exploratory.

Abstract in brief

  • Pharmaceutical-grade chondroitin sulfate (CS) at 800mg/day is as effective as celecoxib 200mg/day and more effective than placebo in reducing pain and improving function in patients with symptomatic knee osteoarthritis over a 6-month period.
  • The study showed significant improvements in pain (measured by VAS) and functional indices (Lequesne Index) for both CS and celecoxib compared to placebo, with no notable difference between the two active treatments.
  • Both CS and celecoxib had excellent safety profiles, supporting the recommendation of pharmaceutical-grade CS as a first-line treatment option for managing knee osteoarthritis symptoms.]
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Alex Lickerman
@AlexLickerman · X

@adamcifu @chadinabhan Speaking of glucosamine, what do you think of this: https://t.co/vABo9mpz9O.

May 21, 2021 · 1 like · 1,488 followers View post →
Osteosyn
@osteosynhealth · X

According to Professor Jean-Yves Reginster’s paper on Annals of the Rheumatic Diseases (2017), Pharmaceutical-grade Chondroitin sulfate is as effective as celecoxib and superior to placebo in symptomatic knee osteoarthritis https://t.co/TeGPcDIMIS

Nov 5, 2019 · 1 like · 1 share · 157 followers View post →

All mentions

Alex Lickerman
@AlexLickerman · X

@adamcifu @chadinabhan Speaking of glucosamine, what do you think of this: https://t.co/vABo9mpz9O.

May 21, 2021 · 1 like · 1,488 followers View post →
LLPH Путин — хуйло
@WeiguoWeiguo · X

RT @OsteosynCenter: According to Professor Jean-Yves Reginster’s paper on Annals of the Rheumatic Diseases (2017), Pharmaceutical-grade Cho…

Nov 5, 2019 · 1 share · 150 followers View post →
Osteosyn
@osteosynhealth · X

According to Professor Jean-Yves Reginster’s paper on Annals of the Rheumatic Diseases (2017), Pharmaceutical-grade Chondroitin sulfate is as effective as celecoxib and superior to placebo in symptomatic knee osteoarthritis https://t.co/TeGPcDIMIS

Nov 5, 2019 · 1 like · 1 share · 157 followers View post →
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