Overall, the discussions demonstrate strong support and active engagement with the research, with users referencing specific data such as the Duke study and emphasizing the safety of HCQ in African Americans. The tone is analytical and sometimes assertive, reflecting a belief that the findings challenge previous assumptions, thereby suggesting the potential for meaningful shifts in medical practice.
AgreementModerate agreement
Most discussions reflect support for the study’s conclusion that hydroxychloroquine is safe for G6PD-deficient individuals, especially in African American populations.
InterestHigh interest
The majority of posts show high interest, referencing specific studies and mechanisms, indicating engagement with the research findings.
EngagementHigh engagement
Many users cite the study directly, discuss related mechanisms like hemolysis risk, and advocate for consideration of treatment implications, demonstrating deep involvement.
ImpactModerate impact
Participants highlight the study’s significance in changing perceptions and treatment protocols, though some discussions remain more informational than decisively impactful.
Abstract in brief
This study reviews the safety of hydroxychloroquine (HCQ) in patients with G6PD deficiency, finding very few cases of hemolysis and none during HCQ use.
The research suggests that not all G6PD-deficient individuals are at high risk for hemolytic anemia, especially those with the African variant, and the data do not support routine G6PD testing before prescribing HCQ.
Overall, the findings indicate that HCQ can be safely used in G6PD-deficient patients, particularly African Americans, with minimal risk of hemolytic episodes during treatment.
See what we covered before:
https://t.co/cdx4EYj8XR
https://t.co/jiU8QenKj8
https://t.co/OE8K4z0kGA
https://t.co/LzuNIFWAC3
https://t.co/Iey8oGnsEB
Mar 8, 2023 · 19 likes · 4 shares · 31,580 followersView post →
EM
Elie Balesh, MD
@eliebalesh · X
@docdomeng That’s the conventional teaching, yes. But this research group at Duke challenged that notion and concluded otherwise. https://t.co/l8BS5zI7fm
No increased cases of hemolysis with G6PD and exposure to HCQ- no role for routine screening or withholding HCQ https://t.co/c9dKUWm10r
Aug 8, 2021 · 9 likes · 2 shares · 350 followersView post →
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David Breslauer
@davidNbreslauer · X
@NGoshay @NtmrInVttm @2RockRidge @NanHayworth @BayerUS Note that there is a published article demonstrating safety of hydroxychloroquine use in African American patients (https://t.co/pRdYRGT2pF)
Mar 20, 2020 · 7 likes · 4 shares · 2,560 followersView post →
LD
Le Doc
@DrFranckClarot · X
@LUppsala @FZores @Damkyan_Omega Ça traîne depuis quelques années et c’est dans la notice du Vidal
https://t.co/fvYSfTrCZN
@Banitoto This article investigates the caution of prescribing HCQ to patients with G6PDH deficiency, they concluded that there is no evidence to support this risk. Additionally, not all patients with G6PDH deficiency are at similar risk for hemolysis
https://t.co/6u4neFcYVP
Jun 3, 2020 · 5 likes · 3 shares · 10,785 followersView post →
Professor Roger Seheult MD discusses recent data showing decreasing COVID-19 death rates and explores the potential role of N-acetylcysteine in reducing inflammation markers in hospitalized patients. Recorded on October…
This video reviews the safety of hydroxychloroquine in G6PD deficiency patients, showing minimal hemolysis risk and suggesting routine testing may not be necessary, especially for African American individuals.
RT @MayKazem: No increased cases of hemolysis with G6PD and exposure to HCQ- no role for routine screening or withholding HCQ https://t.co/…
Aug 9, 2021 · 2 shares · 1,056 followersView post →
MH
May Kazem, MD MHA FRCPC (She/her)
@MayKazem · X
No increased cases of hemolysis with G6PD and exposure to HCQ- no role for routine screening or withholding HCQ https://t.co/c9dKUWm10r
Aug 8, 2021 · 9 likes · 2 shares · 350 followersView post →
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UTSWRheum
@UTSWRheum · X
2017 Duke study: no cases of hemolysis in G6PD def. Rx w/ HCQ found in >700 months exposure. Authors concluded, "These data do not support routine measurement of G6PDH levels or withholding HCQ therapy among African American patients w/G6PDH deficiency." https://t.co/l7NF4NBFWB
Lorsqu'ils discutent d'une hémolyse oxydative potentielle avec l'hydroxychloroquine, les auteurs s'appuient sur le fait qu'ils n'ont pas été détectés sur une petite étude particulière
https://t.co/20DzUz8uxA
@satrapo86 @Covid19Critical There’s no studies with the vac but we see it’s effect on Covid
Here goes thru some of medical studies with it for Covid
https://t.co/QOk9RfJTtG
@SarahSopran0 https://t.co/bxlV1RI9jL
https://t.co/Q5d5FtwFyQ
https://t.co/wDRjPfjapI
I learned about it from medcram (links above) part of my prophylaxis protocol. I have bought from Amazon but now harder to get.
@FlaTesla @US_FDA If they did even the most basic research, they'd be supplementing heavily with vitamin D https://t.co/bXRUCFhfGV and taking NAC https://t.co/aCrsk73eE4
@juliefair Additionally - we use mouthwash with cetylpyridinium chloride (Colgate range + Supermarket own brand) + supplement called NAC (N-Acetylcysteine)
Google it - here is a lecture from reputable Medcram with links to the research.
https://t.co/NcsEIWlm3p
Dec 16, 2020 · 3 likes · 15,045 followersView post →
RT @MedCramVideos: Professor Roger Seheult, MD on #COVID19 updates:
- Death Rate Drops, but why?
- NAC (N-acetylcysteine) data on hospita…
Nov 11, 2020 · 24 shares · 432 followersView post →
MB
Miletich-Barkovich
@Marina87251891 · X
RT @avivajazz: Coronavirus Update 114: COVID-19 Death Rate Among Hospitalized Patients Has Dropped Significantly Since March 2010; NAC (N-a…
Nov 7, 2020 · 1 share · 3,501 followersView post →
IA
I tried to warn y’all!
@CMeroKennedy · X
@Cernovich NAC is also helpful for COVID-19. He starts talking about this around the 6 minute mark. He has other videos (~ 5 months ago) that go through the mechanism in more detail.
I’m going to give it a go since it seems to have several benefits, thanks!
https://t.co/yEFg6BVVvD
@DanielTuijnman @Nicole_Maes @MoniqueMeijde @Vrijheidsvogel Help me dan. Bekijk al die video's die jij EXPRES niet wil zien... Bedrieger die je bent. Vuilak.
https://t.co/PKcuikQ8EQ
https://t.co/xKTfa7usmN
Reduction in mortality percentage in USA and UK studies. #COVID19 https://t.co/2EY0WCssvE @MedCramVideos Significant to covid approach going forward. Treatments assisting Mask wearing? Vit D supplementation or more time outdoors in the sun? https://t.co/khVkUZK4lV
https://t.co/WG7HaVgkfA
Positive cases up deaths rate down.This is the statistic that counts.
Covid cases less serious over 99.97 survival rates and earlier and effective treatments now available.Democratics creating panic for political gain.
Oct 26, 2020 · 3 likes · 1,874 followersView post →
I just love those MedCram videos. Great for reviewing my BioChem mechanisms. Nice to see deaths not going up with cases. https://t.co/xH8XUDpUkJ
Wearing masks reduces virus doses saving lives.
Also turns out NAC is effective for reducing inflammation in severe #COVID19 patients.
@__ice9 @joex92_ @Covid19Crusher @CovidAnalysis @gummibear737 Interesting talk on how HCQ could cause more deaths. Does anyone think this could explain why RECOVERY saw an increased death rate in the treatment group, in stark contrast to all other studies? https://t.co/L0z9oPPywV
RT @JSegor: 10-23-20:
Big drop in COVID-19 death rates study says (US, UK), although current levels still too high, but flat. Here's why. (…
Oct 24, 2020 · 1 share · 3,571 followersView post →
AG
Aviva Gabriel
@avivajazz · X
Coronavirus Update 114: COVID-19 Death Rate Among Hospitalized Patients Has Dropped Significantly Since March 2010; NAC (N-acetylcysteine and COVID-19; Face Masks — October 23, 2020 MedCram Update https://t.co/yFOmtanzKS via @YouTube
Oct 24, 2020 · 1 like · 1 share · 3,571 followersView post →
JN
Just Nic
@NicMCtheold · X
Coronavirus Update 114: COVID 19 Death Rate Drops; NAC (N acetylcysteine... https://t.co/6PCEIwBYxH via @YouTube
You can't necessary add the past data and apply the seasonal effect to find your result. Have to also consider we know how to medically manage this matter.
Good info. Why the death rate dropped and NAC info for those who understands.
https://t.co/t2VCRMubzn
RT @ckwadrat: Badania pokazują, że maseczki i dystans mogą obniżać śmiertelność po zachorowaniu na #COVID19. Z tej prostej przyczyny, że og…
Oct 23, 2020 · 4 shares · 1,241 followersView post →
AM
Abu Shoyeb, MD
@abushoyeb · X
I’ve positive experience with the use of NAC in #COVID19 pts. Today found more anecdotal evidence of benefits of NAC in #Covid19 pts. Original article https://t.co/6th4Zy4RxD
https://t.co/6th4Zy4RxD related video https://t.co/4bfZh9Jima @aafp @AnnalsofIM @JAMA_current @WHO https://t.co/7Mqr2WHzDr
RT @MedCramVideos: Professor Roger Seheult, MD on #COVID19 updates:
- Death Rate Drops, but why?
- NAC (N-acetylcysteine) data on hospita…
Oct 23, 2020 · 24 shares · 311 followersView post →
IL
(Ivan) Vane Leban
@IvanLeban · X
Worthwhile to look at and specially at use of NAC (N-acetyl cisteine) = Fluimukan in hospitalized pacients.
Coronavirus Update 114: COVID 19 Death Rate Drops; NAC (N acetylcysteine... https://t.co/pqQquZPNyG via @YouTube
@chrisdbarnett @LFC_blano Thanks. I was just commenting on the risky behaviour People indigenous to warm climates clot more . With Covid this is a disadvantage, many small clots in the lungs is leading cause of death with most Covid patients.
Medcram do a series of updates https://t.co/GMZ1wpso1m
RT @MedCramVideos: Professor Roger Seheult, MD on #COVID19 updates:
- Death Rate Drops, but why?
- NAC (N-acetylcysteine) data on hospita…
Oct 23, 2020 · 24 shares · 1,269 followersView post →
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LynnFynn3
@LynnFynn3 · X
@axelmeyerko @brithume Well that is actually not accurate. You're talking about a G6PD deficiency, and out of ALL Of the literature of patients with this deletion, there were no cases of hemolysis. Nice they though. ;)
https://t.co/KSu6H2oAW0
@Banitoto This article investigates the caution of prescribing HCQ to patients with G6PDH deficiency, they concluded that there is no evidence to support this risk. Additionally, not all patients with G6PDH deficiency are at similar risk for hemolysis
https://t.co/6u4neFcYVP
Jun 3, 2020 · 5 likes · 3 shares · 10,785 followersView post →
Examination of Hydroxychloroquine Use and Hemolytic Anemia in G6PDH-Deficient Patients. (notice that they examine effects on mainly white women, why when this effects mainly black men?) #watchthehands https://t.co/brprI7vUtf
@OffGuardian0 The trial 'proving' hydroxychloroquine is safe for G6PD-deficient patients was hopelessly skewed towards women. Only 2 G6PD-deficient men were part of the trial, and it's an x-linked disease that affects men far more than women! https://t.co/pNTJGy8emN
@NilooferN @niro60487270 Here it is https://t.co/x7NuiBUaqi
May 11, 2020 · 1 share · 340,325 followersView post →
MB
Marko Da Beast
@BoteekBoteek · X
@MyGreenGypsy @Wewoka3 @zev_dr “These data do not support routine measurement of G6PDH levels or withholding HCQ therapy among African American patients with G6PDH deficiency.”
https://t.co/uXvnlGfVgb
@M_T_Franz jein, aber ich bin kein Mediziner
https://t.co/G6qU4fw66g
+ Wodags Kausalitätsvermutung dank gut belegter Auffälligkeit bei der Sterblichkeit
vs.
https://t.co/4SDdVoFDwm
@NoShoutStandOut @LernerHd @cameronks @EMNerd_ @ThinkingCC @emcrit @emupdates @srrezaie @EMSwami @PulmCrit @painfreeED @precordialthump @EvieMarcolini @4shikaJain @DFarcy @umanamd @gattinon @broomedocs @MRamzyDO @cnnbrk @drsanjaygupta @ChrisCuomo @NYGovCuomo They can’t take chloroquine but can take hydroxychloroquine. It has no adverse effects on g6pd https://t.co/sPGy7vivai
@docdomeng That’s the conventional teaching, yes. But this research group at Duke challenged that notion and concluded otherwise. https://t.co/l8BS5zI7fm
#SciencePrevails #TruthMatters #ClinicianNotes If good people do nothing, evil prevails. Examination of Hydroxychloroquine Use and Hemolytic Anemia in G6PDH-Deficient Patients. - PubMed - NCBI @NAACP @NationalBaptist https://t.co/PQKao8m3t7
RT @davidNbreslauer: @NGoshay @NtmrInVttm @2RockRidge @NanHayworth @BayerUS Note that there is a published article demonstrating safety of…
Mar 20, 2020 · 4 shares · 50,798 followersView post →
DB
David Breslauer
@davidNbreslauer · X
@NGoshay @NtmrInVttm @2RockRidge @NanHayworth @BayerUS Note that there is a published article demonstrating safety of hydroxychloroquine use in African American patients (https://t.co/pRdYRGT2pF)
Mar 20, 2020 · 7 likes · 4 shares · 2,560 followersView post →
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Hydroxychloroquine - Wikipedia | PDF | Pharmacology | Biology
News
doi:10.1002/acr.23296 . PMID 28556555 . 28. Schrezenmeier E, Dörner T (March 2020). "Mechanisms of action of hydroxychloroquine and chloroquine ...
doi:10.1002/acr.23296. ISSN 2151-4658. PMID 28556555. ^ Kalia, S; Dutz, JP (2007). “New Concepts in Antimalarial Use and Mode of Action in Dermatology ...
“Examination of Hydroxychloroquine Use and Hemolytic Anemia in G6PDH-Deficient Patients”. Arthritis Care & Research. 70 (3): 481–485. doi:10.1002/acr.23296.