August 2017 PMID 28572496

Effect of age, diet, and tissue type on PCr response to creatine supplementation.

Marina Yazigi Solis, Guilherme Giannini Artioli, Maria Concepción García Otaduy, Claudia da Costa Leite, Walquiria Arruda, Raquel Ramos Veiga, Bruno Gualano

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Mentions

37
Peak: 6 in Dec 2020
across 6 sources since Oct 2017

Extended reach

115,390
potential audience

Total likes

2,261

Video views

62,781

Mentions per month

Oct 2017 – Sep 2025

Where it's discussed

  • Facebook13 posts
  • X / Twitter9 posts
  • Instagram9 posts
  • News3 articles
  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

The discussions reflect a high level of interest and moderate agreement with the study’s findings, exemplified by words like 'fantastic' and references to specific tissue and age group responses. Posts mentioning tissue-specific effects and brain versus muscle responses indicate deep engagement, while comments about potential applications suggest the study's moderate impact on ongoing research and understanding of creatine supplementation.

AgreementModerate agreement

Most posters acknowledge the significance of the study, with some expressing enthusiasm about its contributions, such as calling it a 'fantastic study' and appreciating its questions addressed.

InterestHigh interest

The posts show high engagement and curiosity, especially with technical details about PCr response differences between tissues and groups.

EngagementModerate engagement

Posters reference specific findings, methodologies, and implications, indicating moderate to deep engagement, especially when discussing tissue-specific responses and potential applications.

ImpactModerate impact

While some posts highlight the importance of understanding creatine's role, the overall perceived impact remains moderate, as it mainly informs future research rather than immediate practice changes.

Abstract in brief

  • The study found that creatine supplementation increased muscle phosphocreatine (PCr) levels in children, vegetarians, and the elderly, but the extent varied with age, diet, and tissue type, with elderly showing the greatest increase.
  • Brain PCr levels did not significantly change with creatine supplementation across any group, and the response was much smaller compared to muscle, indicating tissue-specific differences in creatine uptake or response.
  • The results suggest that creatine supplementation protocols might need to be customized based on age, diet, and tissue type to optimize muscle and possibly brain creatine levels for different populations.]

Top posts

Most liked on X and Bluesky
Sam Impey PhD
@SamImpey_ · X

Today I learnt - skeletal muscle cannot synthesise creatine, but the brain can! Supplementation may increase brain content, but data is unavailable to identify if this can be maintained. https://t.co/Dtq5cQe8tH https://t.co/l5AedzMtbN

Mar 17, 2020 · 24 likes · 3,381 followers View post →
David_Propst_PA-C
@PrimaryCarePAC · X

I just read through Solis 2017 “Effect of age, diet, and tissue type on PCr response to creatine supplementation” It’s a 31P-MRS eval of PCr change in muscle & brain after a 7d #creatine load 0.3 g/kg Compares children, adults & elderly. Compares omnivores and vegetarians. https://t.co/THdO0ViD87

Dec 24, 2020 · 13 likes · 5 shares · 3,329 followers View post →
Kevin Tipton
@proftipper · X

@EricRawsonPhD @PrimaryCarePAC @RBKreider @darrencandow @ScottForbes14 @JoseAntonioPhD @ZiegenfussTim one problem is the human brain, unlike muscle, seems unable to increase Cr in response to supplementation, at least in otherwise healthy individuals. These data from MRS study. https://t.co/rg9yZRqzuz

Feb 15, 2020 · 7 likes · 18,161 followers View post →
Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X

@nick_krontiris @TheNutrivore @marco_machado1 @KostasProko This is a fantastic study that helps address some of the questions. https://t.co/g67lroqV7b

Dec 24, 2022 · 2 likes · 6,741 followers View post →
Bader alshatti Ms
@alshatti_fit · X

RT @PrimaryCarePAC: I just read through Solis 2017 “Effect of age, diet, and tissue type on PCr response to creatine supplementation” It’…

Dec 24, 2020 · 5 shares · 9,794 followers View post →
Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X

RT @PrimaryCarePAC: I just read through Solis 2017 “Effect of age, diet, and tissue type on PCr response to creatine supplementation” It’…

Dec 24, 2020 · 5 shares · 6,741 followers View post →

All mentions

Jérôme OLLIER
@jeromeollier.bsky.social · Bluesky

Actus Mer/Sea News: Via @aims_gov_au @suthicke - Telomere dynamics in the Pacific crown-of-thorns seastar (Acanthaster cf. solaris): effect of age, diet, and tissue type - @SpringerNature http://dlvr.it/SsPmhh

Jul 19, 2023 View post →
Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X

@nick_krontiris @TheNutrivore @marco_machado1 @KostasProko This is a fantastic study that helps address some of the questions. https://t.co/g67lroqV7b

Dec 24, 2022 · 2 likes · 6,741 followers View post →
Argón
@metilargon · X

RT @PrimaryCarePAC: I just read through Solis 2017 “Effect of age, diet, and tissue type on PCr response to creatine supplementation” It’…

Dec 30, 2020 · 5 shares · 349 followers View post →
Bader alshatti Ms
@alshatti_fit · X

RT @PrimaryCarePAC: I just read through Solis 2017 “Effect of age, diet, and tissue type on PCr response to creatine supplementation” It’…

Dec 24, 2020 · 5 shares · 9,794 followers View post →
JB
@theborthface · X

RT @PrimaryCarePAC: I just read through Solis 2017 “Effect of age, diet, and tissue type on PCr response to creatine supplementation” It’…

Dec 24, 2020 · 5 shares · 483 followers View post →
Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X

RT @PrimaryCarePAC: I just read through Solis 2017 “Effect of age, diet, and tissue type on PCr response to creatine supplementation” It’…

Dec 24, 2020 · 5 shares · 6,741 followers View post →
David_Propst_PA-C
@PrimaryCarePAC · X

Read the full study here: https://t.co/0DdelcoIGv

Dec 24, 2020 · 1 share · 3,329 followers View post →
David_Propst_PA-C
@PrimaryCarePAC · X

I just read through Solis 2017 “Effect of age, diet, and tissue type on PCr response to creatine supplementation” It’s a 31P-MRS eval of PCr change in muscle & brain after a 7d #creatine load 0.3 g/kg Compares children, adults & elderly. Compares omnivores and vegetarians. https://t.co/THdO0ViD87

Dec 24, 2020 · 13 likes · 5 shares · 3,329 followers View post →
Sam Impey PhD
@SamImpey_ · X

Today I learnt - skeletal muscle cannot synthesise creatine, but the brain can! Supplementation may increase brain content, but data is unavailable to identify if this can be maintained. https://t.co/Dtq5cQe8tH https://t.co/l5AedzMtbN

Mar 17, 2020 · 24 likes · 3,381 followers View post →
Kevin Tipton
@proftipper · X

@EricRawsonPhD @PrimaryCarePAC @RBKreider @darrencandow @ScottForbes14 @JoseAntonioPhD @ZiegenfussTim one problem is the human brain, unlike muscle, seems unable to increase Cr in response to supplementation, at least in otherwise healthy individuals. These data from MRS study. https://t.co/rg9yZRqzuz

Feb 15, 2020 · 7 likes · 18,161 followers View post →
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