The discussions reflect a high level of interest and moderate agreement with the study’s findings, exemplified by words like 'fantastic' and references to specific tissue and age group responses. Posts mentioning tissue-specific effects and brain versus muscle responses indicate deep engagement, while comments about potential applications suggest the study's moderate impact on ongoing research and understanding of creatine supplementation.
AgreementModerate agreement
Most posters acknowledge the significance of the study, with some expressing enthusiasm about its contributions, such as calling it a 'fantastic study' and appreciating its questions addressed.
InterestHigh interest
The posts show high engagement and curiosity, especially with technical details about PCr response differences between tissues and groups.
EngagementModerate engagement
Posters reference specific findings, methodologies, and implications, indicating moderate to deep engagement, especially when discussing tissue-specific responses and potential applications.
ImpactModerate impact
While some posts highlight the importance of understanding creatine's role, the overall perceived impact remains moderate, as it mainly informs future research rather than immediate practice changes.
Abstract in brief
The study found that creatine supplementation increased muscle phosphocreatine (PCr) levels in children, vegetarians, and the elderly, but the extent varied with age, diet, and tissue type, with elderly showing the greatest increase.
Brain PCr levels did not significantly change with creatine supplementation across any group, and the response was much smaller compared to muscle, indicating tissue-specific differences in creatine uptake or response.
The results suggest that creatine supplementation protocols might need to be customized based on age, diet, and tissue type to optimize muscle and possibly brain creatine levels for different populations.]
Today I learnt - skeletal muscle cannot synthesise creatine, but the brain can!
Supplementation may increase brain content, but data is unavailable to identify if this can be maintained.
https://t.co/Dtq5cQe8tH
https://t.co/l5AedzMtbN
Mar 17, 2020 · 24 likes · 3,381 followersView post →
DC
David_Propst_PA-C
@PrimaryCarePAC · X
I just read through Solis 2017
“Effect of age, diet, and tissue type on PCr response to creatine supplementation”
It’s a 31P-MRS eval of PCr change in muscle & brain after a 7d #creatine load 0.3 g/kg
Compares children, adults & elderly.
Compares omnivores and vegetarians. https://t.co/THdO0ViD87
Dec 24, 2020 · 13 likes · 5 shares · 3,329 followersView post →
KT
Kevin Tipton
@proftipper · X
@EricRawsonPhD @PrimaryCarePAC @RBKreider @darrencandow @ScottForbes14 @JoseAntonioPhD @ZiegenfussTim one problem is the human brain, unlike muscle, seems unable to increase Cr in response to supplementation, at least in otherwise healthy individuals. These data from MRS study.
https://t.co/rg9yZRqzuz
Feb 15, 2020 · 7 likes · 18,161 followersView post →
DF
Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X
@nick_krontiris @TheNutrivore @marco_machado1 @KostasProko This is a fantastic study that helps address some of the questions.
https://t.co/g67lroqV7b
Dec 24, 2022 · 2 likes · 6,741 followersView post →
BM
Bader alshatti Ms
@alshatti_fit · X
RT @PrimaryCarePAC: I just read through Solis 2017
“Effect of age, diet, and tissue type on PCr response to creatine supplementation”
It’…
Dec 24, 2020 · 5 shares · 9,794 followersView post →
DF
Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X
RT @PrimaryCarePAC: I just read through Solis 2017
“Effect of age, diet, and tissue type on PCr response to creatine supplementation”
It’…
Dec 24, 2020 · 5 shares · 6,741 followersView post →
Sleep deprivation negatively impacts cognition, mood, and brain creatine levels, but creatine supplements can mitigate these effects by improving performance and mood during extended wakefulness.
This video explores creatine, its sources, benefits for muscle growth, cognition, and mental health, and addresses whether vegans and vegetarians are deficient. It emphasizes proper dosing, safety, and its role in…
Actus Mer/Sea News: Via @aims_gov_au @suthicke - Telomere dynamics in the Pacific crown-of-thorns seastar (Acanthaster cf. solaris): effect of age, diet, and tissue type - @SpringerNature http://dlvr.it/SsPmhh
@nick_krontiris @TheNutrivore @marco_machado1 @KostasProko This is a fantastic study that helps address some of the questions.
https://t.co/g67lroqV7b
Dec 24, 2022 · 2 likes · 6,741 followersView post →
A
Argón
@metilargon · X
RT @PrimaryCarePAC: I just read through Solis 2017
“Effect of age, diet, and tissue type on PCr response to creatine supplementation”
It’…
Dec 30, 2020 · 5 shares · 349 followersView post →
BM
Bader alshatti Ms
@alshatti_fit · X
RT @PrimaryCarePAC: I just read through Solis 2017
“Effect of age, diet, and tissue type on PCr response to creatine supplementation”
It’…
Dec 24, 2020 · 5 shares · 9,794 followersView post →
J
JB
@theborthface · X
RT @PrimaryCarePAC: I just read through Solis 2017
“Effect of age, diet, and tissue type on PCr response to creatine supplementation”
It’…
Dec 24, 2020 · 5 shares · 483 followersView post →
DF
Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X
RT @PrimaryCarePAC: I just read through Solis 2017
“Effect of age, diet, and tissue type on PCr response to creatine supplementation”
It’…
Dec 24, 2020 · 5 shares · 6,741 followersView post →
DC
David_Propst_PA-C
@PrimaryCarePAC · X
Read the full study here:
https://t.co/0DdelcoIGv
Dec 24, 2020 · 1 share · 3,329 followersView post →
DC
David_Propst_PA-C
@PrimaryCarePAC · X
I just read through Solis 2017
“Effect of age, diet, and tissue type on PCr response to creatine supplementation”
It’s a 31P-MRS eval of PCr change in muscle & brain after a 7d #creatine load 0.3 g/kg
Compares children, adults & elderly.
Compares omnivores and vegetarians. https://t.co/THdO0ViD87
Dec 24, 2020 · 13 likes · 5 shares · 3,329 followersView post →
SP
Sam Impey PhD
@SamImpey_ · X
Today I learnt - skeletal muscle cannot synthesise creatine, but the brain can!
Supplementation may increase brain content, but data is unavailable to identify if this can be maintained.
https://t.co/Dtq5cQe8tH
https://t.co/l5AedzMtbN
Mar 17, 2020 · 24 likes · 3,381 followersView post →
KT
Kevin Tipton
@proftipper · X
@EricRawsonPhD @PrimaryCarePAC @RBKreider @darrencandow @ScottForbes14 @JoseAntonioPhD @ZiegenfussTim one problem is the human brain, unlike muscle, seems unable to increase Cr in response to supplementation, at least in otherwise healthy individuals. These data from MRS study.
https://t.co/rg9yZRqzuz
Feb 15, 2020 · 7 likes · 18,161 followersView post →
... 10.1152/japplphysiol.00248.2017 doi:10.1007/s00726-011-0855-9 doi:10.3390/nu13030877 doi:10.3390/nu14061255 doi:10.3390/nu16213665. Maria Gorete eta beste ...
Pre-Exercise Nutrition Habits and Beliefs of Endurance Athletes ...
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doi:10.1152/japplphysiol.00248.2017. 37. Masson G, Lamarche B. Many non-elite multisport endurance 47. Trabulsi J, Schoeller DA. Evaluation of dietary ...
Age and Diet | PDF | Skeletal Muscle | Magnetic Resonance Imaging
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The PCr signal was quantified relative creatine intake than elderly (P ⬍ 0.0001 for both comparisons). J Appl Physiol • doi:10.1152/japplphysiol.00248.2017 • ...