Aliment Pharmacol Ther August 2017 PMID 28589631

Systematic review: exercise-induced gastrointestinal syndrome-implications for health and intestinal disease.

R J S Costa, R M J Snipe, C M Kitic, P R Gibson

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170

Peak: 11 in Jun 2025

across 5 sources since Mar 2019

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AI synopsis

What people are saying

The overall discussions reveal a balanced recognition of how increased exercise intensity worsens gut health, as seen in remarks about nausea and intestinal permeability; participants use technical language and personal anecdotes, indicating genuine engagement and interest in the health implications of strenuous exercise.

AgreementModerate agreement

Most discussions acknowledge the connection between exercise intensity and gastrointestinal issues, supporting the research findings.

InterestModerate interest

Participants show moderate curiosity, discussing specific symptoms like nausea and gut permeability, indicating genuine interest in the topic.

EngagementModerate engagement

Comments include references to studies, personal experiences, and technical terms, reflecting a decent depth of engagement.

ImpactModerate impact

The discussions highlight concerns for athletes, health implications, and the importance of proper management, suggesting a moderate perceived impact.

Abstract in brief

Exercise-induced gastrointestinal syndrome involves disturbances in gut integrity and function that occur during strenuous exercise, leading to issues like increased intestinal permeability, injury, and malabsorption.
Research shows that increased exercise intensity and duration, especially over 2 hours at high effort levels, significantly worsen gastrointestinal markers such as permeability, endotoxaemia, and motility, with heat stress and running mode making these effects worse.
While moderate exercise can benefit individuals with gastrointestinal conditions, the safety of prolonged strenuous exercise remains uncertain for these populations, as such activity can temporarily impair gut health in healthy people and may pose risks for those with chronic GI disorders.

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Most liked on X and Bluesky

Dr. Beto CoGa

@BetoCortesGale1 · X

El compromiso del flujo sanguíneo intestinal en corredores

Jun 24, 2025 · 48 likes · 10 shares · 2,677 followers View post →

KENTO/カジュアルに栄養の本質を学べる学校を作る。

@sudokeeen · X

参考 https://t.co/FrjUlogoQs

Dec 16, 2022 · 10 likes · 52,155 followers View post →

J P Fanton

@HealthyFellow · X

@RDValerie @_atanas_ @_INPST @ScienceCommuni2 @zbitter @mental_runner @runnersworld @runnersworlduk @MSSEonline @marathonRuns @drnevadagray 2/2 https://t.co/cPDaKRvjab

Jan 9, 2021 · 4 likes · 26,009 followers View post →

Live Vitae

@livevitaeuk · X

https://t.co/GK3XTibRGA

Jul 11, 2022 · 4 likes · 13,059 followers View post →

DisneyBen

@DisneyBen · X

@drkeithsiau @AGA_Gastro https://t.co/6L7Ax44tRE Always found this interesting! @GastroMJB beware!!

May 14, 2023 · 4 likes · 1,962 followers View post →

Alan McCubbin

@nextlvlnut · X

@MMSchube @LJJ_nutrition @steve_mears @c_hulston @SportsRD_PhD Actually upper GI symptoms (especially nausea and urge to vomit) are much more common in runners than lower GI symptoms. Single & multi-stage ultra runners: https://t.co/dId3qAULPk and Systematic RV: https://t.co/7QOW5xvXf0 https://t.co/Lh0Ilg4oHv

Jan 23, 2020 · 2 likes · 1,706 followers View post →

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Join my Email List at httpswwwthomasdelauercom to explore effective post-cardio recovery strategies, including nutritional choices and supplementation. This video emphasizes how proper post-exercise nutrition supports…

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David Estébanez

@trinotas · X

RT @BetoCortesGale1: El compromiso del flujo sanguíneo intestinal en corredores

Jun 25, 2025 · 10 shares · 228 followers View post →

Catalina Pogany

@pogany54 · X

RT @BetoCortesGale1: El compromiso del flujo sanguíneo intestinal en corredores

Jun 24, 2025 · 10 shares · 694 followers View post →

Eduardo Diez Saenz

@saenz_diez · X

RT @BetoCortesGale1: El compromiso del flujo sanguíneo intestinal en corredores

Jun 24, 2025 · 10 shares · 69 followers View post →

Juanmatrix3

@Juanmatrix3 · X

RT @BetoCortesGale1: El compromiso del flujo sanguíneo intestinal en corredores

Jun 24, 2025 · 10 shares · 1,416 followers View post →

Frédéric Roussel

@FredericRou · X

RT @BetoCortesGale1: El compromiso del flujo sanguíneo intestinal en corredores

Jun 24, 2025 · 10 shares · 3,265 followers View post →

Fabio Valencia

@MARATON10 · X

RT @BetoCortesGale1: El compromiso del flujo sanguíneo intestinal en corredores

Jun 24, 2025 · 10 shares · 1,007 followers View post →

Gustavo Susana

@gustavosusana · X

RT @BetoCortesGale1: El compromiso del flujo sanguíneo intestinal en corredores

Jun 24, 2025 · 10 shares · 971 followers View post →

Juan Carlos Lopera

@JuanKLopera · X

RT @BetoCortesGale1: El compromiso del flujo sanguíneo intestinal en corredores

Jun 24, 2025 · 10 shares · 317 followers View post →

Charly117tb

@Charly117tb · X

RT @BetoCortesGale1: El compromiso del flujo sanguíneo intestinal en corredores

Jun 24, 2025 · 10 shares · 1,153 followers View post →

Dagoberto

@Dagorunner · X

RT @BetoCortesGale1: El compromiso del flujo sanguíneo intestinal en corredores

Jun 24, 2025 · 10 shares · 553 followers View post →

Dr. Beto CoGa

@BetoCortesGale1 · X

El compromiso del flujo sanguíneo intestinal en corredores

Jun 24, 2025 · 48 likes · 10 shares · 2,677 followers View post →

Sara Tabares

@saratab · X

A medida que aumenta la intensidad y la duración del ejercicio, aumentan los índices de lesiones intestinales, permeabilidad y endotoxemia, junto con el deterioro del vaciado gástrico y la malabsorción. https://t.co/Eo2LIFwtda

Jun 7, 2023 · 9,324 followers View post →

DisneyBen

@DisneyBen · X

@drkeithsiau @AGA_Gastro https://t.co/6L7Ax44tRE Always found this interesting! @GastroMJB beware!!

May 14, 2023 · 4 likes · 1,962 followers View post →

KENTO/カジュアルに栄養の本質を学べる学校を作る。

@sudokeeen · X

参考 https://t.co/FrjUlogoQs

Dec 16, 2022 · 10 likes · 52,155 followers View post →

Nick Tatt

@nicktatt · X

@simonwakeman Good effort on the ultra distance run. I sometimes suffer from nausea on the ultra distance cycling I've been doing. Tends to happen when the intensity is too high so gut starts to shut down. This article goes into the details https://t.co/xCkSC7pVdq

Sep 30, 2022 · 1 like · 336 followers View post →

Live Vitae

@livevitaeuk · X

https://t.co/GK3XTibRGA

Jul 11, 2022 · 4 likes · 13,059 followers View post →

Erin Kenney, MS, RD, LDN, HCP, CPT

@erinkenneyRD · X

Exercise benefits gut health but too much can actually lead to leaky gut and exacerbate preexisting digestive disorders. https://t.co/Oe66pwZbCS

Jul 9, 2022 · 231 followers View post →

Razvan Bunea

@razvanbunea · X

@davidy4ng

Mar 1, 2022 · 1 like · 201 followers View post →

SystematicReviewBot

@EvidenceRobot · X

RT @BSinger10: Systematic review: exercise-induced gastrointestinal syndrome—implications for health and intestinal disease https://t.co/…

Feb 7, 2022 · 1 share · 6,701 followers View post →

Brett Singer MS,RD,CSSD

@BSinger10 · X

Systematic review: exercise-induced gastrointestinal syndrome—implications for health and intestinal disease https://t.co/9uZuJJ0B2J

Feb 7, 2022 · 1 like · 1 share · 2,816 followers View post →

J P Fanton

@HealthyFellow · X

@RDValerie @_atanas_ @_INPST @ScienceCommuni2 @zbitter @mental_runner @runnersworld @runnersworlduk @MSSEonline @marathonRuns @drnevadagray 2/2 https://t.co/cPDaKRvjab

Jan 9, 2021 · 4 likes · 26,009 followers View post →

Alan McCubbin

@nextlvlnut · X

@MMSchube @LJJ_nutrition @steve_mears @c_hulston @SportsRD_PhD Actually upper GI symptoms (especially nausea and urge to vomit) are much more common in runners than lower GI symptoms. Single & multi-stage ultra runners: https://t.co/dId3qAULPk and Systematic RV: https://t.co/7QOW5xvXf0 https://t.co/Lh0Ilg4oHv

Jan 23, 2020 · 2 likes · 1,706 followers View post →

SystematicReviewBot

@EvidenceRobot · X

RT @AL4Balance: Schematic description of exercise‐induced gastrointestinal syndrome. Costa RJS, Snipe RMJ, Kitic CM, Gibson PR. Systematic…

May 26, 2019 · 1 share · 6,701 followers View post →

Iván Rodríguez

@ivanentrenador1 · X

Schematic description of exercise‐induced gastrointestinal syndrome. Costa RJS, Snipe RMJ, Kitic CM, Gibson PR. Systematic review: exercise-induced gastrointestinal syndrome-implications for health and intestinal… https://t.co/Tu9PrbHsFa

May 26, 2019 · 1 share · 311 followers View post →

danalis

@SummitFuel · X

@EasyontheTummy @Jeukendrup Yes, appreciate your passion. These are foundational concepts clearly discussed in papers referenced + 2019 review @SportsMedicineJ Suggest following @MonashNutrExer for A+ up& coming work w/ low FODMAP https://t.co/tqajhVecpJ. Unpublished data sug. 22% endurance athletes w/ IBS

Mar 29, 2019 · 2 likes · 1,122 followers View post →