Cell Mol Neurobiol April 2018 PMID 28623429

BDNF: A Key Factor with Multipotent Impact on Brain Signaling and Synaptic Plasticity.

Przemysław Kowiański, Grażyna Lietzau, Ewelina Czuba, Monika Waśkow, Aleksandra Steliga, Janusz Moryś

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6
Peak: 2 in Apr 2025
across 3 sources since Jul 2020

Extended reach

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potential audience

Total likes

446

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24,021

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Jul 2020 – Sep 2025

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AI synopsis

What people are saying

Discussions highlight key elements of the article, such as the diverse roles of BDNF in neuron development and signaling, with some posts emphasizing the complexity of its functions, showing a balanced interest and recognition of its potential influence on neuroscience research.

AgreementModerate agreement

Most discussions acknowledge the importance of BDNF in brain functions, indicating general agreement with the article's significance.

InterestModerate interest

Comments reflect a moderate level of curiosity about the detailed signaling pathways and the developmental roles of BDNF.

EngagementModerate engagement

Participants reference specific concepts like synaptic plasticity, neuroprotection, and receptor interactions, showing thoughtful engagement.

ImpactModerate impact

The discussions suggest the article could influence future research directions and understanding of neurological health, implying moderate to high impact.

Abstract in brief

  • BDNF is a widely studied neurotrophin crucial for neuron and glial development, neuroprotection, and the regulation of synaptic interactions that are essential for cognition and memory.
  • Its effects are complex and depend on different forms of BDNF that bind to various receptors, activating multiple signaling pathways which vary according to the stage of brain development and physiological or pathological conditions.
  • Understanding BDNF's role in neurophysiological processes and signaling mechanisms is important for future research on brain development, neuro- and gliogenesis, and synaptic plasticity.]

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Anthony Ellis
@skydog811 · X

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Sep 18, 2025 · 53,413 followers View post →
luis hernan graffe
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RT @hernangraffe: https://t.co/65TXmcHele

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luis hernan graffe
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Apr 30, 2025 · 1 share · 3,163 followers View post →
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com/article/10.1007/s10571-017-0510-4 [5] https://link.springer. com/article/10.1007/s12031-021-01824-8 [6] https://www.frontiersin.org/articles/10.3389 ...

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