August 2017 PMID 28658462

Isotretinoin and Timing of Procedural Interventions: A Systematic Review With Consensus Recommendations.

Leah K Spring, Andrew C Krakowski, Murad Alam, Ashish Bhatia, Jeremy Brauer, Joel Cohen, James Q Del Rosso, Lucia Diaz, Jeffrey Dover, Lawrence F Eichenfield, Geoffrey C Gurtner, C William Hanke, Marla N Jahnke, Kristen M Kelly, Shilpi Khetarpal

Mentions

25
Peak: 1 in Jul 2021
across 5 sources since Jul 2021

Extended reach

21,406
potential audience

Total likes

233

Video views

7,254

Mentions per month

Jul 2021 – Aug 2025

Where it's discussed

  • News14 articles
  • Facebook4 posts
  • X / Twitter3 posts
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

The discussions demonstrate a general consensus supporting the article's findings, with users referencing recent literature and clinical experiences. For example, one user notes that 'many procedural interventions can be conducted while patients are on isotretinoin,' indicating agreement, while another comments on the limited evidence regarding PDT and LLLT, showing engagement with specific treatments. The tone varies from supportive to cautious, reflecting ongoing debates about clinical implications.

AgreementModerate agreement

Most discussions align with the article's conclusion that recent evidence does not strongly support delaying procedures after isotretinoin.

InterestHigh interest

Posts show high interest by referencing specific procedures and studies, indicating active engagement.

EngagementModerate engagement

Comments often include detailed opinions or interpretations of the literature, reflecting moderate engagement.

ImpactModerate impact

The discussions suggest that the article could influence clinical decisions or spark debates about treatment timing, but the impact appears preliminary.

Abstract in brief

  • The idea that systemic isotretinoin increases the risk of abnormal scarring or delayed healing after skin procedures is mainly based on outdated and limited studies from the 1980s.
  • A comprehensive review of recent literature (1982-2017) found insufficient evidence to justify delaying certain skin surgeries or treatments like chemical peels and laser procedures after stopping isotretinoin.
  • Experts recommend that procedures such as dermabrasion and fully ablative laser treatments may not need to be delayed, allowing for more timely interventions when appropriate, though discussions about risks should be personalized between physicians and patients.

Top posts

Most liked on X and Bluesky
John Barbieri, MD, MBA
@DrJohnBarbieri · X

@JiaJia_5555 Many procedural interventions can be conducted while patients are on isotretinoin. However, PDT and particularly LLLT have very limited evidence to suggest they are helpful, so I think low value to combining with isotretinoin for most patients. https://t.co/72K2lipM3O

Aug 31, 2022 · 2 likes · 7,072 followers View post →
John Barbieri, MD, MBA
@DrJohnBarbieri · X

@lacpe12 There is minimal data to support a risk of isotretinoin and abnormal scarring/wound healing. For cutaneous procedures, the consensus is that procedures can be considered during or shortly after isotretinoin (except fully ablative laser or dermabrasion). https://t.co/72K2liHnso

Jul 14, 2021 · 1 like · 7,072 followers View post →

All mentions

ポジティブさん@肌垢
@3707p · X

✍記録2017 JAMA Derm(PMID: 28658462)によるシステマティックレビューでは、イソトレチノイン服用中または直後でも、非アブレーティブレーザー(医療脱毛含む)施術に関する明確な禁止根拠はないと結論。一律「半年空ける」ルールは見直し対象。 https://t.co/O35i8ksJKG

Aug 28, 2025 · 9 followers View post →
John Barbieri, MD, MBA
@DrJohnBarbieri · X

@JiaJia_5555 Many procedural interventions can be conducted while patients are on isotretinoin. However, PDT and particularly LLLT have very limited evidence to suggest they are helpful, so I think low value to combining with isotretinoin for most patients. https://t.co/72K2lipM3O

Aug 31, 2022 · 2 likes · 7,072 followers View post →
John Barbieri, MD, MBA
@DrJohnBarbieri · X

@lacpe12 There is minimal data to support a risk of isotretinoin and abnormal scarring/wound healing. For cutaneous procedures, the consensus is that procedures can be considered during or shortly after isotretinoin (except fully ablative laser or dermabrasion). https://t.co/72K2liHnso

Jul 14, 2021 · 1 like · 7,072 followers View post →