Front Physiol June 2017 PMID 28701960

Role of Mitochondrial Reverse Electron Transport in ROS Signaling: Potential Roles in Health and Disease.

Filippo Scialò, Daniel J Fernández-Ayala, Alberto Sanz

Mentions

10
Peak: 2 in Jul 2019
across 4 sources since Jul 2019

Extended reach

144,077
potential audience

Total likes

480

Video views

12,150

Mentions per month

Jul 2019 – Dec 2025

Where it's discussed

  • X / Twitter4 posts
  • News3 articles
  • YouTube2 videos
  • Reddit1 posts

AI synopsis

What people are saying

Posts demonstrate a genuine interest in mitochondrial ROS signaling, with comments such as 'ROS in mitochondria can be important signaling for mito adaptation and reformation,' showing they find the topic relevant. The tone is analytical, emphasizing concepts like mitochondrial adaptation and the role of reverse electron transport, indicating a thoughtful engagement that recognizes the article's potential significance for health and disease research.

AgreementModerate agreement

Most discussions acknowledge the importance of mitochondrial ROS and RET, suggesting general support for the article's ideas.

InterestModerate interest

Participants seem moderately interested, focusing on the role of ROS in signaling and adaptation rather than dismissing the topic.

EngagementHigh engagement

Posts reference specific concepts like mitochondrial adaptation and the significance of RET, indicating deep engagement.

ImpactModerate impact

The discussions highlight the potential relevance of this research for broader understanding and future applications in health, implying moderate impact.

Abstract in brief

  • Mitochondrial ROS (Reactive Oxygen Species) can cause cellular damage and are linked to aging and diseases like cancer, but they also play important roles in cell signaling and physiological processes.
  • The site of ROS production within mitochondria, especially through a process called reverse electron transport (RET), influences whether ROS have beneficial or harmful effects on cells, with RET-generated ROS aiding in immune responses and adapting to energy or oxygen changes.
  • Recent research highlights that stimulating RET can promote lifespan extension, emphasizing the significance of where ROS are generated, not just how much, in understanding their roles in health and disease.

Top posts

Most liked on X and Bluesky
Frontiers
@FrontiersIn · X

Paper in @FrontPhysiol reviews the current knowledge on #mitochondrial reverse electron transport, its role in Reactive Oxygen Species signaling and its potential implications for the field of #RedoxBiology. #Physiology #Openaccess article: https://t.co/wZIK6sJlHY https://t.co/zzXRmZGwEy

Jul 15, 2019 · 33 likes · 16 shares · 89,886 followers View post →
Tristan Scott
@bitcoinand_beef · X

We know from studies below that ROS in the mitochondria can be important signaling for mito adaptation and reformation. Just b/c CCO is lowered in activity does not mean MB is not helping. Ignoring mitochondrial adpative dynamics is short sighted https://t.co/YjlMlIkLhj

Sep 13, 2023 · 6 likes · 35,379 followers View post →
Pablo Iván Nikel @pabnik.bsky.social
@PabloINik · X

RT @FrontiersIn: Paper in @FrontPhysiol reviews the current knowledge on #mitochondrial reverse electron transport, its role in Reactive Ox…

Jul 15, 2019 · 16 shares · 6,307 followers View post →
Pere Joan Sala
@Fradbius · X

Role of Mitochondrial Reverse Electron Transport in ROS Signaling: Potential Roles in Health and Disease https://t.co/v8jOQWZaSJ

Sep 4, 2019 · 252 followers View post →

All mentions

Tristan Scott
@bitcoinand_beef · X

We know from studies below that ROS in the mitochondria can be important signaling for mito adaptation and reformation. Just b/c CCO is lowered in activity does not mean MB is not helping. Ignoring mitochondrial adpative dynamics is short sighted https://t.co/YjlMlIkLhj

Sep 13, 2023 · 6 likes · 35,379 followers View post →
Pere Joan Sala
@Fradbius · X

Role of Mitochondrial Reverse Electron Transport in ROS Signaling: Potential Roles in Health and Disease https://t.co/v8jOQWZaSJ

Sep 4, 2019 · 252 followers View post →
Pablo Iván Nikel @pabnik.bsky.social
@PabloINik · X

RT @FrontiersIn: Paper in @FrontPhysiol reviews the current knowledge on #mitochondrial reverse electron transport, its role in Reactive Ox…

Jul 15, 2019 · 16 shares · 6,307 followers View post →
Frontiers
@FrontiersIn · X

Paper in @FrontPhysiol reviews the current knowledge on #mitochondrial reverse electron transport, its role in Reactive Oxygen Species signaling and its potential implications for the field of #RedoxBiology. #Physiology #Openaccess article: https://t.co/wZIK6sJlHY https://t.co/zzXRmZGwEy

Jul 15, 2019 · 33 likes · 16 shares · 89,886 followers View post →
Supplementary Materials for
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doi:10.3389/fphys.2017.00428 Medline. 14. R. Fato, C. Bergamini, M. Bortolus, A. L. Maniero, S. Leoni, T. Ohnishi, G. Lenaz,. Differential effects of ...

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Reddit

... 10.3389/fphys.2017.00428/full. H2O2 as a signaling molecule - https://www.jbc.org/article/S0021-9258(20)41952-0/fulltext · Heroine4Life.

Feb 9, 2023 View →