The comments reflect strong support and enthusiasm, exemplified by mentions of the article’s 'rigorous research,' 'clinical implications,' and its high number of citations, illustrating both admiration for its impact and deep engagement with its findings. Words like 'proud,' 'excited,' and references to 'mechanisms of force generation' demonstrate the collaborative and motivated tone of the discussions.
AgreementModerate agreement
Most discussions praise the review's thoroughness, mentioning its importance and reliability, with some referencing it as a valuable resource for understanding muscle adaptations.
InterestHigh interest
The discussions show high interest, with many posts highlighting the relevance of the research to athletic performance and muscle training, as well as expressing pride and enthusiasm.
EngagementHigh engagement
Participants deeply engage by referencing specific findings, authors, and related studies, with some posts summarizing mechanisms or suggesting further integration of knowledge.
ImpactHigh impact
The shared posts indicate the article has a significant impact, being widely cited, highly viewed, and influencing conversations about training methodologies and physiological mechanisms.
Abstract in brief
Eccentric (lengthening) and concentric (shortening) muscle exercises differ in force production, energy cost, and mechanisms of muscle adaptation, with eccentric actions generating more force at a lower metabolic expense, potentially leading to greater muscle hypertrophy.
Research is mixed on whether eccentric or concentric training results in more muscle growth, with some studies favoring one, the other, or showing similar gains; these differences may be due to distinct structural and molecular adaptations in the muscle.
While muscle protein synthesis appears similar after both types of exercise, the underlying molecular mechanisms driving muscle growth and structural changes differ, and matched intensity or workload typically produces comparable hypertrophy through different biological pathways.
ECCENTRIC contractions can generate greater force than CONCENTRIC contractions
➡️ Different mechanisms of FORCE generation
➡️ Implications for conventional resistance training
@MVFranchi #Fridayreading #strength #force
https://t.co/gHVg8ysqfs https://t.co/fYP8TdHfXx
I am proud of this review.
I wrote it in my postdoc in Nottingham @UNAD_Research in between 2 data collections on the topic.
Last week it reached 200 citations (Scopus)
Oct 24, 2023 · 86 likes · 10 shares · 6,012 followersView post →
JN
JP Nunes
@joaonunesjpn · X
Skeletal muscle remodeling in response to eccentric vs. concentric loading: Morphological, molecular, and metabolic adaptations.
@MVFranchi
https://t.co/0cvAjBCKjO
Feb 24, 2023 · 57 likes · 8 shares · 805 followersView post →
PS
Physio Meets Science
@PhysioMeScience · X
Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Adaptations.
https://t.co/CKOpK0OjGh https://t.co/jrQqiIcnn4
Oct 20, 2019 · 54 likes · 16 shares · 93,085 followersView post →
JD
Jeff Taylor-Haas, DPT
@jefftaylorhaas · X
Really cool review paper--worth a read. Clinical implications for many athletic populations! Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Adaptations https://t.co/x2bu35R04A
Nov 12, 2019 · 19 likes · 2 shares · 1,883 followersView post →
YC
Yuya Mukaihara | MS, ATC, CSCS, NCSA-CPT
@Yuuuumuk · X
このレビュー研究では、筋肥大はconcentricでもeccentricでも同じ様に起こる。違いは細かな筋構造上のアダプテーションだそう。
https://t.co/1Vm18yemAL
Dr. Spina氏が言うようにそれぞれ割合が違うだけで、軟部組織は同じ物でできている。
筋肥大している時には腱にも機械刺激が入っている。 https://t.co/81CkaSBxYP
Nov 28, 2020 · 15 likes · 2 shares · 512 followersView post →
My polite and dramafree defense of cheat reps. The study compares concentric and eccentric training effects on muscle size, strength, and molecular responses, highlighting the importance of understanding different…
Eccentric (lengthening) and concentric (shortening) exercises differ in force, energy use, and muscle adaptation. Research shows both can promote growth through different molecular and structural mechanisms, with…
Learn how eccentric and concentric muscle exercises differ in force, energy use, and adaptation mechanisms. Discover how to optimize your training for better muscle growth, injury prevention, and faster recovery.
Dec 3, 2025 · 6 likes · 3 shares · 14,969 followersView post →
O
OJSN
@iamojsn · X
Frontiers | Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Adaptations https://t.co/hj8NhYJoLM
Oct 29, 2025 · 2 likes · 14,969 followersView post →
N
Nakken
@Nakkuru_ken · X
RT @MVFranchi: I am proud of this review.
I wrote it in my postdoc in Nottingham @UNAD_Research in between 2 data collections on the topic.…
Oct 26, 2023 · 10 shares · 28 followersView post →
TA
thesify.ai
@thesify_ai · X
@MVFranchi @VivianAya93 @UNAD_Research We're excited to see Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Adaptations by @MVFranchi #gainingtraction! Your expertise & rigorous research are raising the bar in Physiology. Keep up the fantastic work!
RT @MVFranchi: I am proud of this review.
I wrote it in my postdoc in Nottingham @UNAD_Research in between 2 data collections on the topic.…
Oct 24, 2023 · 10 shares · 283 followersView post →
V
Viviana
@VivianAya93 · X
RT @MVFranchi: I am proud of this review.
I wrote it in my postdoc in Nottingham @UNAD_Research in between 2 data collections on the topic.…
Oct 24, 2023 · 10 shares · 133 followersView post →
M
mafiqjay
@captionburaq · X
RT @MVFranchi: I am proud of this review.
I wrote it in my postdoc in Nottingham @UNAD_Research in between 2 data collections on the topic.…
Oct 24, 2023 · 10 shares · 44 followersView post →
LW
Lorenzo S.Wayne
@LorenzoSWayne · X
RT @MVFranchi: I am proud of this review.
I wrote it in my postdoc in Nottingham @UNAD_Research in between 2 data collections on the topic.…
Oct 24, 2023 · 10 shares · 52 followersView post →
FR
Fernando Rodríguez
@zefernando55 · X
RT @MVFranchi: I am proud of this review.
I wrote it in my postdoc in Nottingham @UNAD_Research in between 2 data collections on the topic.…
Oct 24, 2023 · 10 shares · 2,777 followersView post →
DP
daniel varela PhD
@dr_dvarela_P4T · X
RT @MVFranchi: I am proud of this review.
I wrote it in my postdoc in Nottingham @UNAD_Research in between 2 data collections on the topic.…
Oct 24, 2023 · 10 shares · 921 followersView post →
AC
Alessandro L Colosio
@AleColosio · X
RT @MVFranchi: I am proud of this review.
I wrote it in my postdoc in Nottingham @UNAD_Research in between 2 data collections on the topic.…
Oct 24, 2023 · 10 shares · 271 followersView post →
AF
Andres Felipe
@Anferupu · X
RT @MVFranchi: I am proud of this review.
I wrote it in my postdoc in Nottingham @UNAD_Research in between 2 data collections on the topic.…
Oct 24, 2023 · 10 shares · 51 followersView post →
CL
Cleiton Libardi
@cleiton_libardi · X
RT @MVFranchi: I am proud of this review.
I wrote it in my postdoc in Nottingham @UNAD_Research in between 2 data collections on the topic.…
Oct 24, 2023 · 10 shares · 532 followersView post →
MF
Martino V. Franchi
@MVFranchi · X
I am proud of this review.
I wrote it in my postdoc in Nottingham @UNAD_Research in between 2 data collections on the topic.
Last week it reached 200 citations (Scopus)
Oct 24, 2023 · 86 likes · 10 shares · 6,012 followersView post →
伊P
伊田暁人 IDA Akito, PhD
@akito_ida · X
https://t.co/n1sLDuCdI6
この内容に関わるレビューも貼っておきます。
Mar 4, 2023 · 6 likes · 22,561 followersView post →
AA
Alvaro Alaor
@alvaroalaor · X
RT @joaonunesjpn: Skeletal muscle remodeling in response to eccentric vs. concentric loading: Morphological, molecular, and metabolic adapt…
Feb 25, 2023 · 8 shares · 539 followersView post →
QL
Qinlong Liu
@QinlongLiu · X
RT @joaonunesjpn: Skeletal muscle remodeling in response to eccentric vs. concentric loading: Morphological, molecular, and metabolic adapt…
RT @joaonunesjpn: Skeletal muscle remodeling in response to eccentric vs. concentric loading: Morphological, molecular, and metabolic adapt…
Feb 24, 2023 · 8 shares · 177 followersView post →
SK
Samir Khalil
@SamirMithqal · X
RT @joaonunesjpn: Skeletal muscle remodeling in response to eccentric vs. concentric loading: Morphological, molecular, and metabolic adapt…
Feb 24, 2023 · 8 shares · 7,155 followersView post →
JN
JP Nunes
@joaonunesjpn · X
Skeletal muscle remodeling in response to eccentric vs. concentric loading: Morphological, molecular, and metabolic adaptations.
@MVFranchi
https://t.co/0cvAjBCKjO
Feb 24, 2023 · 57 likes · 8 shares · 805 followersView post →
B
BinaryX
@binaryx_gg · X
RT @DHMov: ECCENTRIC contractions can generate greater force than CONCENTRIC contractions
➡️ Different mechanisms of FORCE generation
➡️…
Nov 2, 2022 · 27 shares · 6,578 followersView post →
JG
Joseph Guarascio
@CoachJoeyG · X
RT @DHMov: ECCENTRIC contractions can generate greater force than CONCENTRIC contractions
➡️ Different mechanisms of FORCE generation
➡️…
Nov 2, 2022 · 27 shares · 36,911 followersView post →
DP
Damian Harper, PhD
@DHMov · X
RT @DHMov: ECCENTRIC contractions can generate greater force than CONCENTRIC contractions
➡️ Different mechanisms of FORCE generation
➡️…
Nov 2, 2022 · 27 shares · 9,589 followersView post →
NQ
9N3QUARTERX
@9N3QUARTERX · X
RT @DHMov: ECCENTRIC contractions can generate greater force than CONCENTRIC contractions
➡️ Different mechanisms of FORCE generation
➡️…
‘When matched for either load or work, similar increase in muscle size is found between ECC & CON RT. However, such hypertrophic changes appear to be achieved through distinct structural adaptations’. https://t.co/T6wm86Xu8E
ECCENTRIC contractions can generate greater force than CONCENTRIC contractions
➡️ Different mechanisms of FORCE generation
➡️ Implications for conventional resistance training
@MVFranchi #Fridayreading #strength #force
https://t.co/gHVg8ysqfs https://t.co/fYP8TdHfXx
@BradSchoenfeld Interesting. Are you inferring a benefit from eccentric work? But some papers (e.g. Franchi’s review/Damas etc ~ 2017) suggest eccentric only “better” due to greater workload, and/or explains MPS during recovery not hypertrophy
https://t.co/P51iatXvdN
Or a different mechanism?
Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Adaptations https://t.co/iY6rppvNck
@bryanjswain @BradSchoenfeld @gustavofpedrosa Hope you invite even @MVFranchi he did very good researches that could integrate the topic so to get a clearer image of the phenomenon
RT @Yuuuumuk: このレビュー研究では、筋肥大はconcentricでもeccentricでも同じ様に起こる。違いは細かな筋構造上のアダプテーションだそう。
https://t.co/1Vm18yemAL
Dr. Spina氏が言うようにそれぞれ割合が違うだけで、…
Nov 28, 2020 · 2 shares · 13,291 followersView post →
YC
Yuya Mukaihara | MS, ATC, CSCS, NCSA-CPT
@Yuuuumuk · X
このレビュー研究では、筋肥大はconcentricでもeccentricでも同じ様に起こる。違いは細かな筋構造上のアダプテーションだそう。
https://t.co/1Vm18yemAL
Dr. Spina氏が言うようにそれぞれ割合が違うだけで、軟部組織は同じ物でできている。
筋肥大している時には腱にも機械刺激が入っている。 https://t.co/81CkaSBxYP
Nov 28, 2020 · 15 likes · 2 shares · 512 followersView post →
RB
rafael barousse
@drbarousse · X
RT @DerekGriffin86: Everything you need to know about CON vs ECC muscle contractions. https://t.co/sVZbYLVvhM https://t.co/YuCzbNxMCe
May 9, 2020 · 80 shares · 1,415 followersView post →
KB
Kevin Cruz Betancort
@Kevincb96 · X
Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Adaptations. ⚡️
https://t.co/LO4EXVlnE6.
RT @jefftaylorhaas: Really cool review paper--worth a read. Clinical implications for many athletic populations! Skeletal Muscle Remodelin…
Nov 12, 2019 · 2 shares · 1,304 followersView post →
JD
Jeff Taylor-Haas, DPT
@jefftaylorhaas · X
Really cool review paper--worth a read. Clinical implications for many athletic populations! Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Adaptations https://t.co/x2bu35R04A
Nov 12, 2019 · 19 likes · 2 shares · 1,883 followersView post →
MG
Michael Grimshaw
@MichaelGrimsh16 · X
RT @PhysioMeScience: Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Ad…
RT @PhysioMeScience: Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Ad…
Oct 21, 2019 · 16 shares · 2,586 followersView post →
KD
Komsak Sinsurin, PT, Ph.D., DPT
@KsinsurinAung · X
RT @PhysioMeScience: Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Ad…
Oct 21, 2019 · 16 shares · 109 followersView post →
OI
Om-itry
@Om_itry · X
RT @PhysioMeScience: Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Ad…
Oct 21, 2019 · 16 shares · 57 followersView post →
DG
Daniel Godeassi
@dangodeassi · X
RT @PhysioMeScience: Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Ad…
Oct 21, 2019 · 16 shares · 203 followersView post →
B
BenjaATC
@BenjaAtc · X
RT @PhysioMeScience: Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Ad…
Oct 21, 2019 · 16 shares · 148 followersView post →
JM
Jose A. Moral-Munoz
@moralmunoz · X
RT @PhysioMeScience: Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Ad…
Oct 20, 2019 · 16 shares · 1,115 followersView post →
L
Luis
@RoCo1796 · X
RT @PhysioMeScience: Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Ad…
Oct 20, 2019 · 16 shares · 314 followersView post →
T
Tenzing
@sherphisio · X
RT @PhysioMeScience: Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Ad…
Oct 20, 2019 · 16 shares · 49 followersView post →
DB
Dr Milos Bojovic
@DrMilosBojovic · X
RT @PhysioMeScience: Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Ad…
Oct 20, 2019 · 16 shares · 636 followersView post →
PS
Physio Meets Science
@PhysioMeScience · X
Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Adaptations.
https://t.co/CKOpK0OjGh https://t.co/jrQqiIcnn4
Oct 20, 2019 · 54 likes · 16 shares · 93,085 followersView post →
DP
Dustin Oranchuk. PhD
@DustinOranchuk · X
@RichSylvester @wildy_jj There are a few excellent reviews on the topic. Including this open access paper by @MVFranchi
https://t.co/KIkzf12S3H
Oct 11, 2019 · 6 likes · 1,062 followersView post →
HH
High Performance Health
@nickcourt81 · X
RT @MVFranchi: New review in @FrontPhysiol
"Eccentric Muscle Contractions: Risks and Benefits"
Along the lines of @JamieDouglasNZ 2017 re…
Oct 9, 2019 · 27 shares · 3,061 followersView post →
MW
Morgan Williams
@drmorgs · X
RT @drmorgs: Frontiers | Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metaboli…
Oct 9, 2019 · 1 share · 1,929 followersView post →
FB
Freddy Brown
@FreddyBrown1984 · X
@jason_tallis Cheers, fella. This one from 2017 is a personal favourite... Can't go wrong if (former teacher and all round #legend) Marco Narici's on a paper! Love the combination of functional and biochemical outcomes! https://t.co/P51iatXvdN
RT @MVFranchi: I'm happy that this review from 2017 is in the top 15 most viewed of @FrontPhysiol Took me almost a year to complete it!
If…
Feb 1, 2019 · 19 shares · 339 followersView post →
TJ
Tiraboschi Julián
@TiraboschiJM · X
RT @MVFranchi: I'm happy that this review from 2017 is in the top 15 most viewed of @FrontPhysiol Took me almost a year to complete it!
If…
Jan 31, 2019 · 19 shares · 305 followersView post →
SM
Sports Medicine
@SportsMedicineJ · X
RT @MVFranchi: I'm happy that this review from 2017 is in the top 15 most viewed of @FrontPhysiol Took me almost a year to complete it!
If…
Jan 31, 2019 · 19 shares · 53,454 followersView post →
JS
Javier Núñez Sánchez
@FJNunez_Sanchez · X
RT @MVFranchi: I'm happy that this review from 2017 is in the top 15 most viewed of @FrontPhysiol Took me almost a year to complete it!
If…
Jan 31, 2019 · 19 shares · 1,461 followersView post →
DM
Dragan Marinkovic
@mrgaga_021 · X
RT @MVFranchi: I'm happy that this review from 2017 is in the top 15 most viewed of @FrontPhysiol Took me almost a year to complete it!
If…
Jan 31, 2019 · 19 shares · 87 followersView post →
SR
Severin Ruoss
@SeverinRuoss · X
RT @MVFranchi: I'm happy that this review from 2017 is in the top 15 most viewed of @FrontPhysiol Took me almost a year to complete it!
If…
Jan 31, 2019 · 19 shares · 56 followersView post →
MS
Marko Stojanovic
@Marko1610976 · X
RT @MVFranchi: I'm happy that this review from 2017 is in the top 15 most viewed of @FrontPhysiol Took me almost a year to complete it!
If…
Jan 31, 2019 · 19 shares · 140 followersView post →
BB
Bernat Buscà
@BernatBusca72 · X
RT @MVFranchi: I'm happy that this review from 2017 is in the top 15 most viewed of @FrontPhysiol Took me almost a year to complete it!
If…
Jan 30, 2019 · 19 shares · 867 followersView post →
BP
Bret Contreras, PhD
@bretcontreras · X
RT @MVFranchi: I'm happy that this review from 2017 is in the top 15 most viewed of @FrontPhysiol Took me almost a year to complete it!
If…
Jan 30, 2019 · 19 shares · 73,527 followersView post →
SS
Strength & Conditioning Society (SCS)
@S_C_Society · X
RT @MVFranchi: I'm happy that this review from 2017 is in the top 15 most viewed of @FrontPhysiol Took me almost a year to complete it!
If…
Jan 30, 2019 · 19 shares · 7,201 followersView post →
MW
Morgan Williams
@drmorgs · X
Frontiers | Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Adaptations | Physiology #SR3S54 https://t.co/51KRKLtd6p
Jan 29, 2019 · 3 likes · 1 share · 1,929 followersView post →
Kカ
KENTO/カジュアルに栄養の本質を学べる学校を作る。
@sudokeeen · X
エキセントリックが筋肥大に優位っていう定説は、今後変わってくるかもね。
Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Adaptations https://t.co/Rq444p8cpx
Jan 23, 2019 · 2 likes · 52,111 followersView post →
Ebubekir Maksimal Hipertrofi Ebook en Güncel | PDF
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10.3389/fphys.2017.00447. 14) Damas F., Libardi C.A., Ugrinowitsch C. The development of skeletal muscle hypertrophy through resistance training: The role ...
Dosis og form: 3–5 g kreatin monohydrat hver dag. Loading er ligegyldigt. Timing er mindre vigtigt, men sørg for at tage det hver dag. Tag det når det passer ...
1 s2 0 s2095254625000523 Main | PDF | Meta Analysis | Skeletal ...
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doi: 10.3389/fphys.2017.00447. 78. Lieber RL, Fridén J. Musculoskeletal balance of the human wrist elucidated using intraoperative laser diffraction. J ...
Frontiers in Physiology 8:1–16 DOI 10.3389/fphys.2017.00447. Frykberg GE, Ha CK. 2015. Movement analysis of sit-to-stand—research informing clinical practice.
bolic adaptations, „Frontiers in Physiology” 2017, 8, 447, DOI: https://doi.org/10.3389/fphys.2017.00447. 29. Schoenfeld B. J., Ogborn D. I., Vigotsky A. D. ...
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