J Am Geriatr Soc October 2017 PMID 28758188

A Systematic Review and Meta-Analysis of The Effect of Low Vitamin D on Cognition.

Alicia M Goodwill, Cassandra Szoeke

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AI synopsis

What people are saying

Many discussions emphasize the potential link between low vitamin D and cognitive decline, using words like 'association' and 'call for further research' that reflect cautious optimism. Some comments highlight the need for more long-term and intervention studies, which suggests a balanced tone focusing on the study's implications without exaggerated claims.

AgreementModerate agreement

Most discussions acknowledge the relationship between low vitamin D and cognition, with some supporting the research while others note the need for further studies.

InterestModerate interest

Overall moderate interest is observed, with commenters referencing the significance of vitamin D in cognitive health and the implications for future research.

EngagementNeutral engagement

Comments tend to summarize or briefly react to the publication without deep analysis, indicating average engagement.

ImpactNeutral impact

The discussions seem to recognize the importance of the study but do not indicate widespread influence on practice or policy yet.

Abstract in brief

  • This systematic review and meta-analysis found that low vitamin D levels are associated with worse cognitive performance and faster cognitive decline in middle-aged and older adults without dementia, but vitamin D supplements haven't yet proven to improve cognition significantly.
  • The study analyzed 26 observational studies and 3 intervention trials, noting that observational data strongly links low vitamin D with poorer cognition, but intervention studies show no clear benefits from taking vitamin D supplements.
  • Researchers suggest that the timing of vitamin D supplementation might be crucial and call for further long-term lifespan studies to identify when and how vitamin D could best help prevent cognitive decline and dementia with aging.

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BaladoCritique : club de lecture médical
@baladocritique.bsky.social · Bluesky

"Intravenous tranexamic acid in gastrointestinal bleeding: A systematic review and meta-analysis of randomized controlled trials." Publié en juillet dans Am J Emerg Med. #MedSky www.sciencedirect.com/science/arti...

Sep 2, 2025 View post →
Open Forum Infectious Diseases
@ofidjournal.bsky.social · Bluesky

Effectiveness and safety of antibiotics in kidney transplant recipients with asymptomatic bacteriuria: a systematic review and meta-analysis of randomised controlled trials ✅ Just Accepted #IDSky

Sep 1, 2025 · 4 likes · 6 shares View post →
UCL Discovery
@ucldiscovery.bsky.social · Bluesky

Open Access UCL Research: School-based mindfulness programmes and executive functions: a systematic review and meta-analysis of complex intervention studies discovery.ucl.ac.uk/id/eprint/10...

Sep 1, 2025 · 1 like View post →
BaladoCritique : club de lecture médical
@baladocritique.bsky.social · Bluesky

"Blood pressure-lowering efficacy of antihypertensive drugs and their combinations: a systematic review and meta-analysis of randomised, double-blind, placebo-controlled trials." Publié ce jour dans le @thelancet.com. #MedSky www.thelancet.com/journals/lan...

Aug 30, 2025 View post →
kinetoplastids papers
@kinetoplastpapers.bsky.social · Bluesky

Assessing the Effects of Moderate to High Dosage of Astaxanthin Supplementation on Lipid Profile Parameters-A Systematic Review and Meta-Analysis of Randomized Controlled Studies pubmed.ncbi.nlm.nih.gov/40872489/

Aug 29, 2025 View post →
European Society for Child and Adolescent Psychiatry
@escaponline.bsky.social · Bluesky

Read it now online and #openaccess in our #ECAP journal: "Immigration detention of children: a systematic review and meta-analysis of physical and #mentalhealth impacts" by Sherif et al: link.springer.com/article/10.1...

Aug 28, 2025 · 1 like View post →
Mushtaq Bilal, PhD
@mushtaqbilalphd.bsky.social · Bluesky

Can inducing laughter improve your mental health? A systematic review of 45 studies comprising 2,547 participants provides evidence that it does.

Aug 28, 2025 · 1 share View post →
u24usa.bsky.social
@u24usa.bsky.social · Bluesky

Gabapentin and Pain; Autism, ADHD, and Prenatal Acetaminophen; Women and Dementia (MedPage Today) -- A systematic review and meta-analysis of randomized controlled trials suggested gabapentin and pregabalin should not be used to reduce pain intensity or sleep disruption in patients with peripheral…

Aug 27, 2025 View post →
Nature Human Behaviour
@nathumbehav.nature.com · Bluesky

In this new paper, Swaryandini et al. present a systematic review and meta-analysis of 53 randomized controlled trials and find that educational interventions can reduce cognitive biases among students. https://www.nature.c... #CognitiveBias #Education

Aug 26, 2025 · 10 likes · 5 shares View post →
Alli Gilmour
@afgilmour.bsky.social · Bluesky

Excited to share a new publication with co-author Tiffany Lam- A Systematic Review and Meta-Analysis of Dual-Certification in Special Education and General Education. Read the full paper here- journals.sagepub.com/doi/10.1177/...

Aug 26, 2025 · 4 likes · 5 shares View post →
drbenweitz.bsky.social
@drbenweitz.bsky.social · Bluesky

The benefits of spirulina and other forms of edible algae for lowering blood pressure--meta-analysis: Edible Algae Reduce Blood Pressure in Humans: A Systematic Review and Meta‐Analysis of Randomised Controlled Trials onlinelibrary.wiley.com

Aug 26, 2025 View post →
M4R10
@psybaxter.bsky.social · Bluesky

The study, a systematic review and meta-analysis of 13 experiments, found that people under the influence of psilocybin responded more slowly to cognitive tasks and, to a lesser extent, made more errors, particularly at higher doses www.psypost.org/cognitive-te...

Aug 25, 2025 · 3 likes · 2 shares View post →
Clinical Infectious Diseases
@cidjournal.bsky.social · Bluesky

A Systematic Review and Meta-analysis of the Effectiveness of Remdesivir to Treat SARS-CoV-2 in Hospitalized Patients: Have the Guidelines Evolved With the Evidence?

Aug 24, 2025 · 17 likes · 11 shares View post →
Open Forum Infectious Diseases
@ofidjournal.bsky.social · Bluesky

Effectiveness and safety of antibiotics in kidney transplant recipients with asymptomatic bacteriuria: a systematic review and meta-analysis of randomised controlled trials ✅ Just Accepted #IDSky

Aug 23, 2025 · 8 likes · 3 shares View post →
BaladoCritique : club de lecture médical
@baladocritique.bsky.social · Bluesky

“Safety and efficacy of steroidal mineralocorticoid receptor antagonists in patients with kidney failure requiring dialysis: a systematic review and meta-analysis of randomised controlled trials.” Publié ce jour dans @thelancet.com. #MedSky www.thelancet.com/journals/lan...

Aug 23, 2025 View post →
Ophthopedia
@ophthalmology.bsky.social · Bluesky

Ophthopedia Update: Efficacy of Oxymetazoline 0.1% in Acquired Blepharoptosis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials #Ophthomology #Eye #Ophthotwitter

Aug 23, 2025 View post →
JMIR Publications
@jmirpub.bsky.social · Bluesky

Reminder>> Effectiveness of #VirtualReality #VR-Based Early Rehabilitation Strategies on #Pain, Sleep, #Anxiety, Balance, Cognition, and Quality of Life in Adult ICU #Patients: A Systematic Review and Meta-Analysis of #RCT #ClinicalTrials (preprint) #openscience #PeerReviewMe #PlanP

Aug 22, 2025 · 2 shares View post →
Ilan Schwartz
@germhuntermd.bsky.social · Bluesky

Effectiveness and safety of antibiotics in kidney transplant recipients with asymptomatic bacteriuria: a systematic review and meta-analysis of randomized controlled trials “Current evidence does not support routine screening & treatment of post-tx ASB in KTRs.” academic.oup.com/ofid/article...

Aug 20, 2025 · 12 likes · 2 shares View post →
LKS for NHS Ambulance Services in England
@lksase.bsky.social · Bluesky

Association of Prehospital Rearrest With Outcome Following Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-Analysis of Observational Studies: Prehospital Emergency Care: Vol 29, No 6 www.tandfonline.com/doi/abs/10.1...

Aug 20, 2025 View post →
Parasite - The Journal
@parasitejournal.bsky.social · Bluesky

Aug 20, 2025 · 4 likes · 4 shares View post →
Gender Superposition
@Nonlocal_Lia · X

@AmyCeleste8 @Natashreo @MarcyRheintgen @Riley_Gaines_ @AGTennessee https://t.co/4RfTS8gfYo MP02-20 A SYSTEMATIC REVIEW AND META-ANALYSIS OF THE EFFECT OF GENDER-AFFIRMING PELVIC SURGERY ON GENDER DYSPHORIA AND BODY IMAGE IN TRANSGENDER PATIENTS | Journal of Urology

Jun 18, 2025 · 1 like · 724 followers View post →
Genes MDPI
@Genes_MDPI · X

RT @Genes_MDPI: Dr. George Chen and colleagues at @YaleMed conducted a systematic review and meta-analysis of the effect of exercise alone…

Feb 11, 2025 · 1 share · 2,065 followers View post →
Genes MDPI
@Genes_MDPI · X

Dr. George Chen and colleagues at @YaleMed conducted a systematic review and meta-analysis of the effect of exercise alone on histological endpoints in biopsy-proven non-alcoholic fatty liver disease (#NAFLD): https://t.co/e80Ta5wZFG https://t.co/uibU2YpmCH

Jul 8, 2024 · 1 share · 2,065 followers View post →
Jesus Ramirez-Bermudez
@JRBneuropsiq · X

@ThosVarley A systematic review and meta-analysis of the effect of clozapine on cognitive functions in patients with treatment-resistant schizophrenia https://t.co/qJfUxR7AQU

Jul 4, 2024 · 31,395 followers View post →
Keith R Laws
@Keith_Laws · X

A systematic review and meta-analysis of the effect of clozapine on cognitive functions in patients with treatment-resistant schizophrenia https://t.co/4wY9GtOv2l Tiny pre-post benefit (effect size 0.11) & lower 95%CI close to zero - couldnt see any discussion of practice effect

Jun 5, 2024 · 2 likes · 4,626 followers View post →
Elderly or Disabled Living
@EDLcharity · X

A systematic review and meta-analysis of the effect of clozapine on cognitive functions in patients with treatment-resistant schizophrenia https://t.co/xQCgEsGquZ #elderlyordisabledliving

Jun 3, 2024 · 1 like · 112 followers View post →
Kille Tölönen
@Neonomide · X

@FitFounder Oh yes it is, for visceral fat that really seems to matter for metabolic health: https://t.co/vqitfdoMxA https://t.co/nODkaJto25

May 14, 2024 · 926 followers View post →
Lorena Suárez Idueta
@LIdueta · X

RT @NewbornToolkit: For #ToolkitTuesday, we're taking a look at this systematic analysis of the effect of administration of azithromycin du…

Feb 27, 2024 · 2 shares · 215 followers View post →
Newborn Toolkit
@NewbornToolkit · X

For #ToolkitTuesday, we're taking a look at this systematic analysis of the effect of administration of azithromycin during pregnancy on perinatal and neonatal outcomes, as part of #InternationalPrenatalInfectionPreventionMonth. Find out more

Feb 27, 2024 · 4 likes · 2 shares · 626 followers View post →
Kille Tölönen
@Neonomide · X

@KnesplTomas @ScepticalDoctor Cardio is better for managing visceral fat and possibly mental health, but RE is better for overall body composition. Losing excess fat always means losing at least some muscle as well, so sufficient RE remains pretty essential, too. Just my two cents. https://t.co/vqitfdpkn8 https://t.co/Ak7wjE4L2F

Jan 8, 2024 · 2 likes · 926 followers View post →
Pᴜʙʟɪᴄ Uɴᴅᴇʀsᴛᴀɴᴅɪɴɢ ᴏғ Sᴄɪᴇɴᴄᴇ
@SciPublic · X

A systematic review and meta-analysis of the effect of #neuroscience information on perception and understanding of the topic. By Elizabeth Bennett & Peter McLaughlin Watch the video ⬇️ https://t.co/GxaMOEUnDT Read the full article ⬇️ https://t.co/6COgcBAyfU #scicomm https://t.co/tzNeT50g6x

Nov 2, 2023 · 4 likes · 3,328 followers View post →
Public Health Lit
@PublicHealthLit · X

A systematic review and meta-analysis of the effect of digital game-based or influencer food and non-alcoholic beverage marketing on children and adolescents: Exploring hierarchy of effects outcomes https://t.co/lJbLbjc0d1

Oct 4, 2023 · 2 likes · 3,970 followers View post →
Elderly or Disabled Living
@EDLcharity · X

A systematic review and meta-analysis of the effect of clozapine on cognitive functions in patients with treatment-resistant schizophrenia #elderlyordisabledliving https://t.co/Uqo1RwL0ve

Oct 1, 2023 · 112 followers View post →
Life Science Publications
@lsn_publication · X

A systematic review and meta-analysis of the effect of high-intensity statin on coronary microvascular dysfunction. #science #publication #research #publications https://t.co/eAjg05Gx3I

Jul 25, 2023 · 113 followers View post →