@RolandSB13 @dirkcremer @KJPGehrden @degampraesident Auch bei den ebenfalls häufigen #allostatischen Reaktionen (die gerade für #Psychiatrie und #Psychosomatik von besonderer Bedeutung sind), ist die #TSH-Bestimmung wenig geeignet, hier aber eher aus Gründen der #Spezifität als der #Sensitivität. https://t.co/3cfcPtEA7B
Thyroid Allostasis-Adaptive Responses of Thyrotropic Feedback Control to Conditions of Strain, Stress, and Developmental Programming.
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Apr 2019 – Jun 2023Where it's discussed
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X / Twitter31 posts
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Blogs3 articles
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YouTube2 videos
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What people are saying
Several discussions exemplify a thoughtful examination of the article, with people referencing related research reviews, the significance of allostatic responses during critical illness, and psychiatric conditions. For instance, terms like 'complex networks' and 'adaptive responses' are used thoughtfully to emphasize the scientific depth, reflecting a high level of interest and engagement. The tone is informative and scholarly, contributing to a nuanced understanding of how thyroid functions adapt under different stress conditions.
Many posts acknowledge the importance or relevance of the publication, with some explicitly referencing the concept of thyroid allostasis and its significance in different medical conditions.
Posts demonstrate high curiosity by discussing complex mechanisms like the hypothalamic-pituitary-thyroid feedback loop, and referencing related conditions such as critical illness or psychiatric disorders.
Several discussions delve into detailed interpretations of the research, mentioning specific phenomena like NTIS, TACITUS, and the adaptive responses of thyroid regulation, indicating deep cognitive involvement.
While the influence of the publication appears notable among those in the field of endocrinology and mental health, the overall immediate impact perception is moderate, as the posts are more analytical and theoretical rather than describing direct clinica
Abstract in brief
- This article explains how the hypothalamus-pituitary-thyroid system adapts to different types of stress, such as illness, energy deprivation, and psychosocial factors, through a process called thyroid allostasis, which involves changing thyroid hormone levels to help the body cope.
- It distinguishes between different stress responses: type 1 allostasis occurs during illness and energy deficits, leading to decreased thyroid hormone levels, while type 2 allostasis, associated with psychosocial stress and other conditions, can cause an opposite adaptive response.
- The paper also discusses the nonthyroidal illness syndrome (NTIS) or TACITUS, a common pattern in hospitalized patients where thyroid hormone levels are altered—decreased in severe illness or during recovery—and emphasizes the importance of understanding these adaptive mechanisms for accurate diagnosis and treatment.]
Top posts
Most liked on X and BlueskyThe #setpoint of #thyroid #homeostasis may be elevated in the acute phase of #schizophrenia spectrum disorders. This reflects type 2 #allostatic_load. https://t.co/3cfcPtEA7B https://t.co/83e0DgQIQe https://t.co/7gNpy0HBV8
Thyroid function Test. Chatzitomaris, A. et al. (2017) ‘Thyroid allostasis-adaptive responses of thyrotropic feedback control to conditions of strain, stress, and developmental programming’, Frontiers in Endocrinology, 8(JUL), pp. 1–28. doi: 10.3389/fendo.2017.00163 https://t.co/fRlFHRijUc
@SPINATeam ...and it confirms our own earlier observations in the #NHANES dataset. https://t.co/3cfcPtEA7B https://t.co/83e0DgQIQe https://t.co/2toIo270dg
@drraviele @Dominik_Linz @ABollmannMD @rafavidalperez @AnastasiaSMihai @MDTolgaAksu @JonPicciniSr @PrashSanders @LuigiDiBiaseMD @TJaredBunch Another question is if type 2 #thyroid #allostasis in obesity could be an independent mediator for the development of atrial fibrillation. High T3 syndrome due to allostatic load might be a previously overlooked key actor. @dr_pmueller https://t.co/3cfcPtEA7B
@aliloweth @MaryS58459511 @ThyroidBritish @britishthyroid @Soc_Endo @ETA_Thyroid @ThyroidTrust @AmThyroidAssn @youngdiab @SfE_thyronet Regarding allostatic responses of the feedback loop, which may raise or reduce TSH secretion, I would like to refer to our own review article from 2017. https://t.co/3cfcPtEA7B
All mentions
Thyroid Dysfunction in Takotsubo Syndrome Insights and Implications
Abnormal thyroid function, especially elevated free T4 levels and hyperthyroidism, is common in patients with takotsubo syndrome, indicating a stress-related endocrine response. The study highlights the role of thyroid…
Thyroid Allostasis and Adaptive Responses to Stress and Illness
This video explores how the hypothalamus-pituitary-thyroid system adapts to stress, illness, and developmental factors through thyroid allostasis, highlighting different stress response types and their clinical…
RT @drjwdietrich: @aliloweth @MaryS58459511 @ThyroidBritish @britishthyroid @Soc_Endo @ETA_Thyroid @ThyroidTrust @AmThyroidAssn @youngdiab…
@aliloweth @MaryS58459511 @ThyroidBritish @britishthyroid @Soc_Endo @ETA_Thyroid @ThyroidTrust @AmThyroidAssn @youngdiab @SfE_thyronet Regarding allostatic responses of the feedback loop, which may raise or reduce TSH secretion, I would like to refer to our own review article from 2017. https://t.co/3cfcPtEA7B
@Age_and_Ageing Recently, the name "Thyroid allostasis in critical illness, tumours and uraemia" (TACITUS) has been suggested. It may be more appropriate. See https://t.co/TilY9IIScS for a review article.
@5ter_Timo_vl @HDstabil 2. Generell sind Typ-1- und Typ-2-allostatische Reaktionen des #Hypophysen-#Schildrüsen-#Regelkreises zu berücksichtigen, gerade bei kritischer Erkrankung und #ICU-Therapie. #Allostase https://t.co/3cfcPtEA7B https://t.co/OwfopCixbT
@richcollins This review articles summarises some of the scenarios involved: https://t.co/3cfcPtF7X9
@RolandSB13 @dirkcremer @KJPGehrden @degampraesident Auch bei den ebenfalls häufigen #allostatischen Reaktionen (die gerade für #Psychiatrie und #Psychosomatik von besonderer Bedeutung sind), ist die #TSH-Bestimmung wenig geeignet, hier aber eher aus Gründen der #Spezifität als der #Sensitivität. https://t.co/3cfcPtEA7B
RT @drjwdietrich: The #setpoint of #thyroid #homeostasis may be elevated in the acute phase of #schizophrenia spectrum disorders. This refl…
RT @drjwdietrich: The #setpoint of #thyroid #homeostasis may be elevated in the acute phase of #schizophrenia spectrum disorders. This refl…
The #setpoint of #thyroid #homeostasis may be elevated in the acute phase of #schizophrenia spectrum disorders. This reflects type 2 #allostatic_load. https://t.co/3cfcPtEA7B https://t.co/83e0DgQIQe https://t.co/7gNpy0HBV8
@mendesthiagob What makes the interpretation even more complex is the fact that the #allostatic pattern of #NTIS / #ESS / #TACITUS depends on the phase of #illness. In acute disease it is slightly different from that in wasting syndrome. https://t.co/3cfcPtEA7B https://t.co/xkDbFDdold
@DavySRan A comprehensive introduction has been published as an open access article: https://t.co/TilY9IIScS
@FionaPWME @dr_kevinlee The full text of this paper is freely available from https://t.co/3cfcPtEA7B
@FionaPWME @drjwdietrich And is it surprising that one of the energy balancing systems we have- Thyroid - has allostasis responses https://t.co/LmBFyIjroo https://t.co/kJnbvomPeW
@Herzspitze @rosarote_viggo Frage: Warum Lithium? Bipolare Erkrankung? Depression? Leider ist die Schilddrüsenfunktion bei affektiven Erkrankungen schwierig zu beurteilen, Typ-1-Allostase bei Depression, mitunter Typ 2 bei bipolaren Störungen. https://t.co/83e0DgQIQe
For comparison, we observed a positive correlation between #BMI and #JTI in the large #NHANES dataset. https://t.co/3cfcPtEA7B 2/4 https://t.co/JT5GS65SQW
RT @drjwdietrich: @SPINATeam ...and it confirms our own earlier observations in the #NHANES dataset. https://t.co/3cfcPtEA7B https://t.co/8…
@SPINATeam ...and it confirms our own earlier observations in the #NHANES dataset. https://t.co/3cfcPtEA7B https://t.co/83e0DgQIQe https://t.co/2toIo270dg
@EThyroidCancer Substitution therapy of low-T3 sydrome remains to represent a controvery. https://t.co/83e0DgQIQe https://t.co/94fbtrrzAl
@dr_kevinlee @ProfDocHealth The BMI correlates to SPINA-GD and Jostel's TSH index. We have shown this with the NHANES dataset a few years ago. https://t.co/zeHVlGtUK4
@ProfDocHealth @dr_kevinlee We have written a review article including this topic a few years ago: https://t.co/3cfcPtEA7B
@drraviele @Dominik_Linz @ABollmannMD @rafavidalperez @AnastasiaSMihai @MDTolgaAksu @JonPicciniSr @PrashSanders @LuigiDiBiaseMD @TJaredBunch Another question is if type 2 #thyroid #allostasis in obesity could be an independent mediator for the development of atrial fibrillation. High T3 syndrome due to allostatic load might be a previously overlooked key actor. @dr_pmueller https://t.co/3cfcPtEA7B
Thyroid function Test. Chatzitomaris, A. et al. (2017) ‘Thyroid allostasis-adaptive responses of thyrotropic feedback control to conditions of strain, stress, and developmental programming’, Frontiers in Endocrinology, 8(JUL), pp. 1–28. doi: 10.3389/fendo.2017.00163 https://t.co/fRlFHRijUc
@JenHSebring https://t.co/83e0DgQIQe may be helpful.
RT @drjwdietrich: #Hypothalamic neurons integrate multiple afferences to the set point of #thyroid #homeostasis and encode it as #TRH. http…
RT @SimThyrTeam: Simulations w/ #SimThyr help to understand central components of #TACITUS syndrome. #NTIS #Thyroid #TACITUS_Syndrome https…
RT @drjwdietrich: Different conditions and diseases predispose to type 1 and type 2 #thyroid #allostasis, respectively. https://t.co/eGC83i…
RT @drjwdietrich: #NTIS has two related, but distinct phenotypes, #TACITUS in acute #disease and #WastingSyndrome in chronic #illness. http…
RT @drjwdietrich: Complex networks linking #amygdala & #hypothalamus mediate type 2 #Thyroid_Allostasis in #PTSD & #PsychiatricDisease http…
RT @CanadianThyroid: Don't be blinded by TSH. Look at the #T3 and T4 disorders that TSH cannot see. Chatzitomaris et al(2017). "Thyroid All…
RT @CanadianThyroid: Don't be blinded by TSH. Look at the #T3 and T4 disorders that TSH cannot see. Chatzitomaris et al(2017). "Thyroid All…
RT @drjwdietrich: Low #T3 and high reverse T3 mark the endocrine signature of #Thyroid_Allostasis in #starvation. #rT3 #Leptin https://t.c…
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