Nutrients August 2017 PMID 28777294

Common Genetic Variants Alter Metabolism and Influence Dietary Choline Requirements.

Ariel B Ganz, Kevin C Klatt, Marie A Caudill

Mentions

36
Peak: 1 in Oct 2019
across 5 sources since Oct 2019

Extended reach

33,388
potential audience

Total likes

219

Video views

5,543

Mentions per month

Oct 2019 – Aug 2025

Where it's discussed

  • News27 articles
  • Facebook3 posts
  • X / Twitter2 posts
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

The discussions reflect overall enthusiasm for the research, with posts noting how genetic variants influence fertility and Alzheimer's through lipid synthesis, while specific references to effects under different dietary conditions demonstrate engagement with the study's implications. The tone varies from informative to mildly humorous, highlighting both scientific curiosity and personal relevance.

AgreementModerate agreement

Several posts highlight the relevance of genetic factors in dietary requirements, showing partial agreement with the publication's findings.

InterestHigh interest

Discussion mentions impactful topics like fertility and Alzheimer's, indicating high interest in the research implications.

EngagementModerate engagement

Posts relate the research to broader topics and suggest potential mechanisms, reflecting moderate engagement.

ImpactModerate impact

Some posts suggest that understanding genetic variation could influence personalized nutrition or disease understanding, signifying a recognized moderate impact.

Abstract in brief

  • Common genetic variants significantly impact how our bodies metabolize choline and influence individual dietary needs, especially in different biological sexes and reproductive states.
  • The current evidence shows that genetic differences in enzymes related to choline and folate pathways are linked to risks of nutrient inadequacy, whether in conditions of nutrient deficiency or adequacy.
  • Incorporating genetic information into dietary guidelines could help tailor choline intake recommendations more accurately for diverse populations, but further research is needed to fully implement these personalized approaches.]

Top posts

Most liked on X and Bluesky
Kevin C. Klatt, PhD, RD
@KCKlatt · X

Colleagues and I summarized the work from several post hoc analyses of human feeding/intervention studies under different dietary conditions showing common genetic variants influence choline requirements/metabolism (big effects of geno when fed def diets): https://t.co/woKiBTrqQw

Jul 7, 2022 · 5 likes · 1 share · 21,131 followers View post →
UltimApe
@ultimape · X

@KetoAurelius funny enough mutations assocaited with choline synthesis seem to play a role in human fertility https://t.co/fBhVzakFmT and how much you need depends on genetic factors. https://t.co/V9puMIBvXU Effects on Alzheimer's is interesting; it suggests action thru lipid synthesis.

Oct 14, 2019 · 1 like · 6,713 followers View post →

All mentions

Kevin C. Klatt, PhD, RD
@KCKlatt · X

Colleagues and I summarized the work from several post hoc analyses of human feeding/intervention studies under different dietary conditions showing common genetic variants influence choline requirements/metabolism (big effects of geno when fed def diets): https://t.co/woKiBTrqQw

Jul 7, 2022 · 5 likes · 1 share · 21,131 followers View post →
UltimApe
@ultimape · X

@KetoAurelius funny enough mutations assocaited with choline synthesis seem to play a role in human fertility https://t.co/fBhVzakFmT and how much you need depends on genetic factors. https://t.co/V9puMIBvXU Effects on Alzheimer's is interesting; it suggests action thru lipid synthesis.

Oct 14, 2019 · 1 like · 6,713 followers View post →