Transl Psychiatry August 2017 PMID 28809857

Grandmaternal stress during pregnancy and DNA methylation of the third generation: an epigenome-wide association study.

F Serpeloni, K Radtke, S G de Assis, F Henning, D Nätt, T Elbert

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19
Peak: 1 in Aug 2020
across 5 sources since Aug 2020

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Aug 2020 – Nov 2024

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AI synopsis

What people are saying

Discussions reflect personal and societal reflections on historical stress, as seen in mentions of the struggles faced by Black women decades ago, emphasizing the social importance of understanding intergenerational health impacts without engaging deeply with the scientific mechanisms.

AgreementModerate agreement

The discussion acknowledges the significance of ancestral stress, aligning with the article's focus on transgenerational epigenetic effects, though it doesn't fully endorse the scientific details.

InterestNeutral interest

The discussion shows mild interest by highlighting historical stress experiences without delving deeply into the research findings.

EngagementModerate engagement

The mention of societal issues like racial stress indicates a thoughtful engagement, prompting reflection but lacking in technical analysis.

ImpactModerate impact

The focus on historical stress and its potential biological implications points to a moderate recognition of the study’s relevance to social health issues.

Abstract in brief

  • The study investigates how stress experienced by grandmothers during pregnancy can influence DNA methylation patterns in their grandchildren, potentially affecting health outcomes across generations.
  • Researchers found five specific DNA methylation sites significantly associated with grandmaternal exposure to interpersonal violence, particularly affecting genes involved in the circulatory system.
  • The findings suggest that DNA methylation may serve as a biological mechanism for transmitting the effects of prenatal stress across generations and could help identify biomarkers for future health issues.]

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@WitchesFor · X

@TheAntiprude00 Maybe not distant ancestral relatives, but think about the stress & anxiety black women had to endure 20, 30, 50, 60 years ago. . Grandmaternal stress during pregnancy and DNA methylation of the third generation: an epigenome-wide association study https://t.co/xXTcU7wASU

Aug 25, 2020 · 3,165 followers View post →

All mentions

NO_TO_RIOT_BLOCKCHAIN_BITCOIN_MINE
@WitchesFor · X

@TheAntiprude00 Maybe not distant ancestral relatives, but think about the stress & anxiety black women had to endure 20, 30, 50, 60 years ago. . Grandmaternal stress during pregnancy and DNA methylation of the third generation: an epigenome-wide association study https://t.co/xXTcU7wASU

Aug 25, 2020 · 3,165 followers View post →