Mol Neurobiol June 2018 PMID 28840449

From Mitochondrial Function to Neuroprotection-an Emerging Role for Methylene Blue.

Donovan Tucker, Yujiao Lu, Quanguang Zhang

Mentions

44
Peak: 7 in Feb 2025
across 4 sources since Mar 2020

Extended reach

307,624
potential audience

Total likes

1,104

Video views

41,438

Mentions per month

Mar 2020 – Sep 2025

Where it's discussed

  • X / Twitter36 posts
  • Facebook3 posts
  • News3 articles
  • YouTube2 videos

AI synopsis

What people are saying

Overall, discussions reflect strong agreement and high interest, exemplified by remarks indicating methylene blue's promising therapeutic potential and references to scientific studies, as well as references to its historical safety and current research efforts, demonstrating moderate engagement and perceived significance.

AgreementModerate agreement

Most discussions acknowledge and support the potential benefits of methylene blue based on the research, with some emphasizing its safety and historical use.

InterestHigh interest

Participants show high enthusiasm, referencing multiple studies, methods, and applications, indicating strong curiosity and engagement with the topic.

EngagementModerate engagement

Comments include comparisons, personal experiences, and mentions of ongoing research, showing active participation, though not deeply technical.

ImpactModerate impact

The discussions suggest recognition of the article’s importance for health and neuroprotection, with some references to potential medical and therapeutic implications.

Abstract in brief

  • Methylene blue (MB) is a versatile drug traditionally used for treating malaria and other conditions, but recent research highlights its role in supporting mitochondrial function by increasing electron transfer, which reduces oxidative stress and promotes mitochondrial health.
  • MB also helps decrease neuroinflammation and has shown promising results in protecting neurons in various animal models of neurodegenerative diseases like Alzheimer's, Parkinson's, stroke, and traumatic brain injury, making it a potential therapeutic option.
  • The review emphasizes the connection between mitochondrial health, neurogenesis, and improved cognition, suggesting that MB could be important in combating age-related cognitive decline by enhancing neural resilience and function.]

Top posts

Most liked on X and Bluesky
Deborah Gordon, M.D.
@DrDeborahMD · X

@DrNeilStone WTF??!! It's also a dye used in routine med lab staining and studied for cognitive and urological benefits. Don't judge a substance just by the company it keeps. Here's one of many--if pub med keeps working. https://t.co/SNuP63M3NC

Mar 4, 2025 · 10 likes · 3,764 followers View post →
Denis, NP
@Denis_protocol · X

From Mitochondrial Function to Neuroprotection – An Emerging Role for Methylene Blue https://t.co/ep8GJCcHEO

Apr 25, 2023 · 5 likes · 1 share · 9,129 followers View post →
Chris Palmer, MD
@ChrisPalmerMD · X

@dan_hues @seconds_0 https://t.co/JKd04og6ZK

Jul 8, 2023 · 3 likes · 1 share · 136,280 followers View post →
Likepiterathome
@likepiterathome · X

@MagnetoDark @mitokondriac Existen investigaciones sobre enfermedades degenerativas como el alzheimer y Parkinson, donde el azul de metileno tiene efectos positivos!! https://t.co/02AHplD2v5 https://t.co/uEYXFRS7jM https://t.co/ynPf9gubr9 https://t.co/DNHlse5lSs

Mar 29, 2022 · 3 likes · 1 share · 276 followers View post →
BadTexanKitty
@OpenZoociety · X

@pooltitans @ReconJackUSMC https://t.co/TZLQgJqZyE https://t.co/nMW6qY6e7R https://t.co/JxJ35eOasP

Nov 20, 2024 · 2 likes · 22,928 followers View post →
Lina
@Linaguasca · X

La disfunció mitocondrial s'ha identificat com un fenomen patològic aparentment unificador en una àmplia gamma de trastorns neurodegeneratius, la qual cosa posiciona el BLAU de METILÈ com a terapèutic prometedor.https://t.co/vZSZ333Z51 https://t.co/ThuqHFZpXN

Nov 19, 2024 · 2 likes · 1 share · 7,272 followers View post →

All mentions

Walter Wartenweiler (e/acc)
@Waltika · X

@CCogitationis @DrNeilStone You don’t know how to use google / grok? https://t.co/sdPQVf67mL From Mitochondrial Function to Neuroprotection-an Emerging Role for Methylene Blue - PubMed

Jul 9, 2025 · 1 like · 31,820 followers View post →
Lily GraceSABY
@LilyGraceSABY · X

RT @LilyGraceSABY: "From Mitochondrial Function to Neuroprotection-An Emerging Role for Methylene Blue" https://t.co/PrRunAY1TB Author manu…

Mar 17, 2025 · 3 shares · 4,862 followers View post →
Clime This
@woogawogga · X

@gorskon @DrNeilStone A bit more on the pathway for effects of methylene blue. Improvement of mitochondrial activity. I saw a report that it was being tried for ME/CFS long covid. https://t.co/7F7Gq38GUL

Mar 4, 2025 · 1 like · 371 followers View post →
Deborah Gordon, M.D.
@DrDeborahMD · X

@DrNeilStone WTF??!! It's also a dye used in routine med lab staining and studied for cognitive and urological benefits. Don't judge a substance just by the company it keeps. Here's one of many--if pub med keeps working. https://t.co/SNuP63M3NC

Mar 4, 2025 · 10 likes · 3,764 followers View post →
Elisheva
@Elisheva_Jeshua · X

From Mitochondrial Function to Neuroprotection-an Emerging Role for Methylene Blue https://t.co/tK6ut98Qr5

Feb 12, 2025 · 993 followers View post →
Ritual Health
@myritualhealth · X

The CEO Tier Brain Supplement Of RFK Jr #methyleneblue #singapore malaysia #supplements Sources: https://t.co/BJd7826XWM https://t.co/xvYpA3RMer https://t.co/FGiJZcDFuv

Feb 11, 2025 · 4 followers View post →
Karen
@Rambat · X

@NerdyPearl89 @kuaroo_ @j00ny369T Why would I be afraid? I've already posted a bunch of them. Are you not able to do your own searches? https://t.co/hDahBGq7fD https://t.co/ZutOOy3ihH https://t.co/0u5h9lICI3 https://t.co/7SarJw7rfY https://t.co/9AQUtxrCUs https://t.co/zesz2zlr0u https://t.co/TsvKL5O6HQ

Feb 7, 2025 · 7,076 followers View post →
Ryanfbt
@ryanfbt · X

@AlastairMcA30 @VanceE https://t.co/ARWqLK510S https://t.co/04mpIdBX2x

Feb 6, 2025 · 1,609 followers View post →
JonDoe69
@jondoe__69 · X

@EichholtzAlex https://t.co/prhakWA8yf https://t.co/kavQ2WXzRu

Feb 6, 2025 · 2 likes · 184 followers View post →
Porfreyja
@evagariten · X

@emzorbit It has a long history of efficacy and safety. https://t.co/IF45epac01

Feb 6, 2025 · 1 like · 2 followers View post →
Noam Inkfeather
@NoamInkfeather · X

@AlanLevinovitz Tucker D, Lu Y, Zhang Q. From Mitochondrial Function to Neuroprotection-an Emerging Role for Methylene Blue. Mol Neurobiol. 2018 Jun;55(6):5137-5153. doi: 10.1007/s12035-017-0712-2. Epub 2017 Aug 24. PMID: 28840449; PMCID: PMC5826781.

Feb 6, 2025 · 209 followers View post →
J.B. Shaw
@RefocusOpen · X

@prof_mdhooghe @SynBioC @VIB_CMB @ELSchemistry @UofT @LabScribbles @KU_Leuven @CSB_UGent @XStruct_group @FbwUGent LabScribbles, “Mitochondrial Function to Neuroprotection- an Emerging role for Methylene Blue” (paywall article) https://t.co/Zwh2SjUiog Enjoy

Jan 26, 2025 · 139 followers View post →
Donny York
@donnyork · X

RT @LilyGraceSABY: "From Mitochondrial Function to Neuroprotection-An Emerging Role for Methylene Blue" https://t.co/PrRunAY1TB Author manu…

Jan 15, 2025 · 3 shares · 2,805 followers View post →
Lily GraceSABY
@LilyGraceSABY · X

RT @LilyGraceSABY: "From Mitochondrial Function to Neuroprotection-An Emerging Role for Methylene Blue" https://t.co/PrRunAY1TB Author manu…

Jan 15, 2025 · 3 shares · 4,862 followers View post →
Lily GraceSABY
@LilyGraceSABY · X

"From Mitochondrial Function to Neuroprotection-An Emerging Role for Methylene Blue" https://t.co/PrRunAY1TB Author manuscript; available in PMC: 2019 Jun 1.Mol NeurobiolPublished in final edited form as: Mol Neurobiol. 2017 Aug 24;55(6):5137–5153. doi: 10.1007/s12035-017-0712-2

Jan 15, 2025 · 2 likes · 3 shares · 4,862 followers View post →
BadTexanKitty
@OpenZoociety · X

@pooltitans @ReconJackUSMC https://t.co/TZLQgJqZyE https://t.co/nMW6qY6e7R https://t.co/JxJ35eOasP

Nov 20, 2024 · 2 likes · 22,928 followers View post →
Manu_K_talà ✌️
@Manu_K_tala · X

RT @Linaguasca: La disfunció mitocondrial s'ha identificat com un fenomen patològic aparentment unificador en una àmplia gamma de trastorns…

Nov 19, 2024 · 1 share · 5,355 followers View post →
Lina
@Linaguasca · X

La disfunció mitocondrial s'ha identificat com un fenomen patològic aparentment unificador en una àmplia gamma de trastorns neurodegeneratius, la qual cosa posiciona el BLAU de METILÈ com a terapèutic prometedor.https://t.co/vZSZ333Z51 https://t.co/ThuqHFZpXN

Nov 19, 2024 · 2 likes · 1 share · 7,272 followers View post →
Kinetic Knowledge
@Kdub_ishere · X

https://t.co/RSRxn583xR

May 30, 2024 · 1 like · 48 followers View post →
Markus | Lifehacker 3.0
@lundeee · X

@JuhaKoukkari @BetoniJankko @tkaasalainen @olliposti Ohops! Tämä teollisuuden väriaine on sittekin melko mielenkiintoinen substanssi myös terveyskulmasta tarkasteltuna. Toki media sanoo nykyisin painavimman sanan, eli turha sinänsä koittaa tieteeseen tukeutua.

May 24, 2024 · 2,917 followers View post →
SpaceX Force Fan
@SpaceForce369 · X

Methylene Blue https://t.co/snyZ5B8lGe https://t.co/oxmu6K4QJM

Jan 31, 2024 · 5,285 followers View post →
Euglena
@DrPurpo · X

@RyukaStark Pues sorprendentemente si que tiene sus usos... https://t.co/IZb1bAC3Tq https://t.co/BOZ6H2HK1a https://t.co/lOXjsHKvkX

Dec 5, 2023 · 1 like · 211 followers View post →
Believer
@DestinyRoxx · X

From Mitochondrial Function to Neuroprotection-an Emerging Role for Methylene Blue. https://t.co/u1CCHYNEbf

Sep 16, 2023 · 4,914 followers View post →
Patrick
@pkamaukinyenje · X

RT @ChrisPalmerMD: @dan_hues @seconds_0 https://t.co/JKd04og6ZK

Jul 10, 2023 · 1 share · 711 followers View post →
Chris Palmer, MD
@ChrisPalmerMD · X

@dan_hues @seconds_0 https://t.co/JKd04og6ZK

Jul 8, 2023 · 3 likes · 1 share · 136,280 followers View post →
Cyberdelic
@Toxicfacez · X

@Christina_Wood1 @MaxKonigMD @LCalabreseDO @DamanLangguth @adamcifu @fitterhappierAJ Hi, have you tried gut healing with them? Kefir, kombucha, CoQ10, Sauerkraut, red light therapy and the famous methylen blue? ✌️ https://t.co/2vnjOvwmV3

Jul 6, 2023 · 168 followers View post →
Danielle; We The People
@daosunshine · X

RT @Denis_protocol: From Mitochondrial Function to Neuroprotection – An Emerging Role for Methylene Blue https://t.co/ep8GJCcHEO

May 29, 2023 · 1 share · 1,049 followers View post →
Chalkboard
@12chalksticks · X

From Mitochondrial Function to Neuroprotection-an Emerging Role for Methylene Blue. https://t.co/NJVq3xDoJ7

May 20, 2023 · 3 followers View post →
Ghost in the Machine
@checkeredcareer · X

From Mitochondrial Function to Neuroprotection-an Emerging Role for Methylene Blue. https://t.co/ko4jUauyOJ

May 20, 2023 · 2 followers View post →
Random Doggy
@randomdogginess · X

@BrandonGilles I take it just 'cus, and for mitochondria. Though tbh haven't noticed much from it. This might have good info: https://t.co/5W6KLDW3rd

May 3, 2023 · 1 like · 2,361 followers View post →
Denis, NP
@Denis_protocol · X

From Mitochondrial Function to Neuroprotection – An Emerging Role for Methylene Blue https://t.co/ep8GJCcHEO

Apr 25, 2023 · 5 likes · 1 share · 9,129 followers View post →
Respira App
@respira_app · X

@RootsHarmonic https://t.co/hAhpjjneX3

Apr 17, 2023 · 664 followers View post →
darktolight
@MagnetoDark · X

RT @likepiterathome: @MagnetoDark @mitokondriac Existen investigaciones sobre enfermedades degenerativas como el alzheimer y Parkinson, don…

Mar 29, 2022 · 1 share · 1,987 followers View post →
Likepiterathome
@likepiterathome · X

@MagnetoDark @mitokondriac Existen investigaciones sobre enfermedades degenerativas como el alzheimer y Parkinson, donde el azul de metileno tiene efectos positivos!! https://t.co/02AHplD2v5 https://t.co/uEYXFRS7jM https://t.co/ynPf9gubr9 https://t.co/DNHlse5lSs

Mar 29, 2022 · 3 likes · 1 share · 276 followers View post →
amor_fati
@MotoSpecialcom · X

@mitokondriac https://t.co/rTQJdIdnav - https://t.co/BAgxyytoiT - https://t.co/ERUAwUbgXA - https://t.co/AEcxbEZIAW - https://t.co/FeJsNp3XqS - https://t.co/PwUm2gRmO4 - https://t.co/xIW8yrjrWA - https://t.co/vN88u4Nl1B - https://t.co/XZsKB7Omyq varios enlaces separados por -

Apr 17, 2021 · 1 like · 38 followers View post →
DocDmcl
@DmclDoc · X

From Mitochondrial Function to Neuroprotection-an Emerging Role for Methylene Blue. https://t.co/w8xdj6hOqu

Apr 1, 2020 · 1 like · 987 followers View post →