Cell Metab October 2017 PMID 28918936

Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota.

Guolin Li, Cen Xie, Siyu Lu, Robert G Nichols, Yuan Tian, Licen Li, Daxeshkumar Patel, Yinyan Ma, Chad N Brocker, Tingting Yan, Kristopher W Krausz, Rong Xiang, Oksana Gavrilova, Andrew D Patterson, Frank J Gonzalez

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Mentions

108
Peak: 4 in Apr 2019
across 7 sources since Oct 2017

Extended reach

57,341
potential audience

Total likes

278

Video views

4,583

Mentions per month

Oct 2017 – Jul 2025

Where it's discussed

  • Facebook66 posts
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  • News6 articles
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  • YouTube3 videos
  • Bluesky1 posts

AI synopsis

What people are saying

Overall, the discussions reflect a positive perception with enthusiasm for the findings, illustrated by phrases like 'promising mechanism' and 'game changer.' Users show interest through detailed references to physiological processes such as gut microbiota shaping and fat browning, demonstrating a meaningful engagement and recognition of its potential for impactful health interventions.

AgreementStrong agreement

Most discussions highly support the findings, emphasizing the positive implications for health and obesity management.

InterestHigh interest

The discussions show strong curiosity, with many users highlighting potential benefits and mechanisms like fat browning and gut microbiota changes.

EngagementModerate engagement

Several comments reference specific scientific concepts and applications, indicating active participation and deeper understanding.

ImpactHigh impact

The community perceives this research as highly influential, mentioning its promising role in treating obesity and improving metabolic health.

Abstract in brief

  • Intermittent fasting, specifically an every-other-day fasting (EODF) regimen, promotes the formation of beige fat within white adipose tissue, leading to reductions in obesity, insulin resistance, and liver fat accumulation.
  • The process involves changes in gut microbiota composition, which increase fermentation products like acetate and lactate, helping to stimulate beige fat development; microbiota depletion prevents this beiging effect.
  • Transferring microbiota from fasting mice to microbiota-depleted mice activates fat browning and improves metabolic health, highlighting a gut microbiome-driven mechanism for combating obesity and related metabolic diseases.]

Top posts

Most liked on X and Bluesky
IntegralAnswers
@IntegralAnswers · X

2F/ PubMed Result for PMID 28924244 •Title: Intermittent fasting promotes white adipose browning and decreases obesity by shaping the gut microbiota •Authors: Li G, Xie C, Lu S, et al. •Journal: Cell Metabolism (2017)

Jul 18, 2025 · 8 likes · 7,894 followers View post →
BowTiedPhys
@BowTiedPhys · X

[1]: https://t.co/4ImE6zZoGh [2]: https://t.co/fGdxbyme3t [3]: https://t.co/53xtYVu8DB [4]: https://t.co/NecpAMYkQJ [5]: https://t.co/VvD7BkTwq9 [6]: https://t.co/yXCk2KjW4J [7]: https://t.co/7KDG6DTtrZ [8]: https://t.co/gDHTwGNzyE [9]: https://t.co/fBPZpk63Cx [10]:

Oct 17, 2024 · 3 likes · 1 share · 26,349 followers View post →
Ruben Murcia Prieto
@RubenMurciaPrie · X

Li, G et al. Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota. Bianchi, G et al. Fasting induces anti-Warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models.

Apr 8, 2019 · 2 likes · 3 shares · 8,877 followers View post →
やまだ@腸活×アンチエイジング
@tarou_ymd_ · X

Feb 21, 2023 · 2 likes · 6,272 followers View post →
Daniel Hernández
@Danitubo · X

RT @RubenMurciaPrie: Li, G et al. Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota.…

Apr 8, 2019 · 3 shares · 2,290 followers View post →
ENDALA klinika zdraví
@endalaclinic · X

Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota https://t.co/PVUlJpzjTf

Nov 13, 2020 · 252 followers View post →

All mentions

IntegralAnswers
@IntegralAnswers · X

2F/ PubMed Result for PMID 28924244 •Title: Intermittent fasting promotes white adipose browning and decreases obesity by shaping the gut microbiota •Authors: Li G, Xie C, Lu S, et al. •Journal: Cell Metabolism (2017)

Jul 18, 2025 · 8 likes · 7,894 followers View post →
PlanetOptimism
@planetoptimism · X

RT @BowTiedPhys: [1]: https://t.co/4ImE6zZoGh [2]: https://t.co/fGdxbyme3t [3]: https://t.co/53xtYVu8DB [4]: https://t.co/NecpAMYkQJ [5]: h…

Oct 18, 2024 · 1 share · 92 followers View post →
BowTiedPhys
@BowTiedPhys · X

[1]: https://t.co/4ImE6zZoGh [2]: https://t.co/fGdxbyme3t [3]: https://t.co/53xtYVu8DB [4]: https://t.co/NecpAMYkQJ [5]: https://t.co/VvD7BkTwq9 [6]: https://t.co/yXCk2KjW4J [7]: https://t.co/7KDG6DTtrZ [8]: https://t.co/gDHTwGNzyE [9]: https://t.co/fBPZpk63Cx [10]:

Oct 17, 2024 · 3 likes · 1 share · 26,349 followers View post →
Bubba Rowan
@Mariano_Cornell · X

@AlpacaAurelius ... start burning fat for energy. This can lead to weight loss and body fat reduction. BUT that's not, by any means, necessarily bad. Source: "Cell Metabolism" Magazine. "Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota"

Jul 28, 2023 · 62 followers View post →
Cristian Estrella
@imestrellakris · X

https://t.co/DmwRbcvTyN

Mar 6, 2023 · 53 followers View post →
やまだ@腸活×アンチエイジング
@tarou_ymd_ · X

Feb 21, 2023 · 2 likes · 6,272 followers View post →
RRID Robot
@RobotRrid · X

RRIDs were included in the Cell Metabolism paper "untitled" (https://t.co/KfpAhO7LmW). We appreciate the author's support of reproducibility. #OpenScience #ReproducibleResearch

Aug 29, 2021 · 161 followers View post →
RRID Robot
@RobotRrid · X

RRIDs were included in the Cell Metabolism paper "Intermittent Fasting Promotes White Adipose Browni…" (https://t.co/KfpAhO7LmW). RRIDs like this improve reproducibility in scientific research. #reproducibility #STMpublishing

Aug 1, 2021 · 161 followers View post →
ENDALA klinika zdraví
@endalaclinic · X

Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota https://t.co/PVUlJpzjTf

Nov 13, 2020 · 252 followers View post →
EMIN-Endocrinologia
@EMIN_Endocri · X

RT @RubenMurciaPrie: Li, G et al. Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota.…

Apr 8, 2019 · 3 shares · 147 followers View post →
Daniel Hernández
@Danitubo · X

RT @RubenMurciaPrie: Li, G et al. Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota.…

Apr 8, 2019 · 3 shares · 2,290 followers View post →
chema
@chemax8a · X

RT @RubenMurciaPrie: Li, G et al. Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota.…

Apr 8, 2019 · 3 shares · 121 followers View post →
Ruben Murcia Prieto
@RubenMurciaPrie · X

Li, G et al. Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota. Bianchi, G et al. Fasting induces anti-Warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models.

Apr 8, 2019 · 2 likes · 3 shares · 8,877 followers View post →
Marcus Böhme
@boehmemarcus.bsky.social · Bluesky

Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota http://www.cell.com/cell-metabolism/fulltext/S1550-4131(17)30504-1

Oct 5, 2017 View post →