April 2017 PMID 28983518

Evidence for a Large-Scale Brain System Supporting Allostasis and Interoception in Humans.

Ian R Kleckner, Jiahe Zhang, Alexandra Touroutoglou, Lorena Chanes, Chenjie Xia, W Kyle Simmons, Karen S Quigley, Bradford C Dickerson, Lisa Feldman Barrett

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121

Peak: 47 in Apr 2023

across 5 sources since Jul 2020

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AI synopsis

What people are saying

Many discussions highlight specific themes from the publication, such as the idea that the boundaries separating physical and mental health are artificial constructs. Phrases like 'the brain is not architected with distinct psychological circuits' and 'co-morbid fatigue, anxiety, and depression' illustrate a deep commitment to exploring these interconnected themes. The choice of words reflects concern and excitement over the research's implications, pointing to the recognition of intertwined wellness and health issues.

AgreementStrong agreement

The overwhelming sentiment reflects strong support for the article's assertions related to the interconnectedness of psychological and physiological systems.

InterestHigh interest

Participants express high interest in the findings and implications, mentioning the relevance to mental and physical health discussions.

EngagementModerate engagement

While many show acknowledgment of the research, the engagement depth varies, with a few commenters diving into specifics about implications.

ImpactHigh impact

Users recognize the publication’s potential to influence future research and understanding of mental and physical health.

Abstract in brief

Researchers discuss a newly identified brain system dedicated to interoception, which processes internal body sensations, similar to existing systems for external senses like sight and sound.
The study uses advanced imaging techniques and data from monkeys and humans to explore this interoceptive system's role in regulating allostasis, or how the body maintains stability.
Findings suggest a strong link between brain connectivity in this system and interoceptive ability, which could help bridge the gap between mental and physical health issues.

Read the full abstract

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FND Portal - is no longer on X

@FndPortal · X

@Z3R0Gravitas Instead of "one cause" we frame predisposing, precipitating, and perpetuating factors, which jointly impact core systems that respond to multiple types of stressors - physiological and "psychological" (which is also physiology). This is the way! https://t.co/RU6Zk3EYK7

Nov 24, 2024 · 6,933 followers View post →

Live Landmark

@Livelandmark · X

@LenaFoxfoot Les om EPIC-modellen? Embodied Predictive Interoception Coding https://t.co/KdZ2iDMmHu

Feb 12, 2024 · 3,084 followers View post →

Kirito (e/acc)

@bronzeagepapi · X

RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jan 13, 2024 · 39 shares · 4,546 followers View post →

Jeremy G

@WhoAreYouMate · X

RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Dec 25, 2023 · 56 shares · 45 followers View post →

zenoist.republican @anarchomorphist.bsky.social

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Dec 25, 2023 · 56 shares · 1,519 followers View post →

Weijie Huang

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Dec 25, 2023 · 56 shares · 11 followers View post →

Cristian Torres

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Dec 25, 2023 · 56 shares · 69 followers View post →

thmonk

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Dec 25, 2023 · 56 shares · 1,636 followers View post →

CLaE

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Dec 25, 2023 · 56 shares · 28,164 followers View post →

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@FndPortal · X

@MentalHealthLaw @ProfRobHoward @MECFSNews @nataliesurely In other words, it might be possible to imagine a hypothetical brain in which psychological function is somehow separated out from other biological processes, but what really matters is the actual brain we have. And the human brain is not built that way. https://t.co/RU6Zk3EYK7

Jul 28, 2023 · 6,933 followers View post →

Nayef Al-Rodhan

@SustainHistory · X

RT @SustainHistory: Evidence for a large-scale brain system supporting #Allostasis-and-#Interoception in humans Implications include insig…

Jul 7, 2023 · 2 shares · 53,344 followers View post →

University of Science, Technology and Arts (USTA)

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jul 3, 2023 · 39 shares · 1,085 followers View post →

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jul 1, 2023 · 39 shares · 2,526 followers View post →

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CLaE

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

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Bayar Jaff

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 606 followers View post →

kokako

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 6 followers View post →

Edwin Roberto Ramírez Benítez

@EdwinRobertoRa4 · X

RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 80 followers View post →

Huang, Fei-Yang 黃飛揚

@HuangFY_tw · X

RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 478 followers View post →

Tyson Sawchuk PhD RPsych

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 51 followers View post →

Beto Fuentes

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 1,773 followers View post →

REMAP Therapeutics

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 1,289 followers View post →

Camille Grasso

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 280 followers View post →

Carlos Sandoval

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 78 followers View post →

Juliet L. King PhD, ATR-BC, LPC, LMHC ⚡️

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 667 followers View post →

Leonhard Schilbach

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 6,747 followers View post →

tiina parviainen

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 932 followers View post →

Hipocrates Juniors

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 2,537 followers View post →

Jinwoo Lee

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 268 followers View post →

Rei Akaishi

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 2,856 followers View post →

Uggiee

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 11 followers View post →

Sev

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 98 followers View post →

Nayef Al-Rodhan

@SustainHistory · X

Jun 30, 2023 · 3 likes · 2 shares · 53,344 followers View post →

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 379 followers View post →

Psicólogo Celestino González-Fernández ψ

@Tecnoestres · X

RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 2,902 followers View post →

robot.design

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 392 followers View post →

Jeong-Kyu Han

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 341 followers View post →

T Tian

@gdsttian · X

RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 137 followers View post →

Mya

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 572 followers View post →

Abel Losada Esperante #IWantToBelieve #SkynetCult

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 5,071 followers View post →

Ester Desfilis

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 482 followers View post →

Arianna Sala

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 495 followers View post →

Jesus Ramirez-Bermudez

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 31,280 followers View post →

Ryoichi WATANABE, PhD.

@watanaberkyoto · X

RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.c…

Jun 30, 2023 · 39 shares · 4,028 followers View post →

CLaE

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Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co/DkzUbGOOrr

Jun 30, 2023 · 156 likes · 39 shares · 28,164 followers View post →

אמT

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 28, 2023 · 56 shares · 6 followers View post →

Nazareth Castellanos

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 28, 2023 · 56 shares · 8,661 followers View post →

N.S.

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 26, 2023 · 56 shares · 23 followers View post →

Marco Marino

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 26, 2023 · 56 shares · 186 followers View post →

Octavian Jurma

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 25, 2023 · 56 shares · 269 followers View post →

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 25, 2023 · 56 shares · 5,704 followers View post →

Marcia Petyt

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 25, 2023 · 56 shares · 988 followers View post →

Pat

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 25, 2023 · 56 shares · 679 followers View post →

尾呂内平太

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 25, 2023 · 56 shares · 17 followers View post →

JoaquimLamora

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 25, 2023 · 56 shares · 1,133 followers View post →

Saúl Ríos Cano

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 25, 2023 · 56 shares · 166 followers View post →

Cos

@ceudamente · X

RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 25, 2023 · 56 shares · 27 followers View post →

Johanna Luise Mayer

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 25, 2023 · 56 shares · 102 followers View post →

Jasmina is a PhD student

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 25, 2023 · 56 shares · 588 followers View post →

CLaE

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 25, 2023 · 56 shares · 28,164 followers View post →

Reza Rasulipour

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 25, 2023 · 56 shares · 44 followers View post →

elsewhere

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 25, 2023 · 56 shares · 2,175 followers View post →

Leonardo Viana

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 25, 2023 · 56 shares · 904 followers View post →

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 17 followers View post →

Jibran Khokhar

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 10,800 followers View post →

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 89 followers View post →

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 308 followers View post →

Rafaela Collo

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 1 followers View post →

y itaguchi

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 882 followers View post →

Nathalie George

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 248 followers View post →

octavio

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 331 followers View post →

Joe Chilcot

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 990 followers View post →

Xzistor LAB

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 529 followers View post →

Alex Galvez-Pol @alexgalvezpol.bsky.social

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 2,526 followers View post →

Dr.Calleros-Zubiate

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 2,582 followers View post →

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Apr 24, 2023 · 56 shares · 862 followers View post →

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 40 followers View post →

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 158 followers View post →

Juan

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 305 followers View post →

Richard Imrich

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 154 followers View post →

Claudio Babiloni

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 662 followers View post →

Henning M Reimann

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 181 followers View post →

MH. Rahmani

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Vahid Behzadan

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 1,124 followers View post →

Ke Bo

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

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Lizette Neves

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

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Marcus van der Erve✨

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 2,087 followers View post →

FND Portal - is no longer on X

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 6,933 followers View post →

Anna Ciaunica @annaciaunica.bsky.social

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 13,869 followers View post →

Neurosys

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RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 409 followers View post →

vulnerant omnes, ultima necat

@dawn_of_dawn · X

RT @leafs_s: Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co…

Apr 24, 2023 · 56 shares · 729 followers View post →

CLaE

@leafs_s · X

Nature Human Behaviour Evidence for a large-scale brain system supporting allostasis and interoception in humans https://t.co/DkzUbGOOrr

Apr 24, 2023 · 210 likes · 56 shares · 28,164 followers View post →

Tom Plender

@TomPlender · X

RT @FndPortal: And when people say things like “FND isn’t a physiological disorder,” I know why that’s not true. https://t.co/RU6Zk3FwzF

Oct 11, 2022 · 2 shares · 2,716 followers View post →

wolodya

@wolodya · X

RT @FndPortal: And when people say things like “FND isn’t a physiological disorder,” I know why that’s not true. https://t.co/RU6Zk3FwzF

Oct 10, 2022 · 2 shares · 1,072 followers View post →

FND Portal - is no longer on X

@FndPortal · X

And when people say things like “FND isn’t a physiological disorder,” I know why that’s not true. https://t.co/RU6Zk3FwzF

Oct 10, 2022 · 4 likes · 2 shares · 6,933 followers View post →

David Ortega

@davidortegab · X

"The brain continually anticipates the body’s energy needs in an efficient manner and prepares to meet those needs before they arise" — "Evidence for a large-scale brain system supporting allostasis and interoception in humans" By Kleckner I. 2017

Aug 15, 2022 · 589 followers View post →

FND Portal - is no longer on X

@FndPortal · X

To add to this, the brain is not architected with distinct psychological circuits.

Jul 5, 2022 · 9 likes · 6,933 followers View post →

FND Portal - is no longer on X

@FndPortal · X

Cites paper with @iankleckner on core brain networks underlying physiological regulation (and many other functions, including emotion). “They are also implicated in FND” https://t.co/RU6Zk3EYK7

Jun 20, 2022 · 2 likes · 6,933 followers View post →

Gema B. Prieto

@GemaBPrieto · X

RT @Fisioterapia4D: Evidence for a large-scale brain system supporting allostasis and interoception in humans. Nature Human Behavior, 1, Ar…

May 29, 2022 · 1 share · 14 followers View post →

#Fisioterapia4D

@Fisioterapia4D · X

Evidence for a large-scale brain system supporting allostasis and interoception in humans. Nature Human Behavior, 1, Article 0069. https://t.co/AmwPB9yr7N — #Fisioterapia #Fisioterapeutas #Conocimiento #Profesionales #RPG #Neuroplasticidad #Sanidad #Fisioterapia4D #Salud

May 28, 2022 · 1 like · 1 share · 1,237 followers View post →

Ian Kleckner PhD MPH (he/him)

@iankleckner · X

The boundaries that separate physical disorders from mental disorders were CREATED, not discovered, by human brains. E.g., explaining co-morbid fatigue, anxiety, and depression alongside physical stress after surgery. For more neuro behind this idea: https://t.co/4j1p4d9lGa https://t.co/Kr4Ud0vaDW

Apr 6, 2022 · 1 like · 945 followers View post →

Lisa Feldman Barrett

@LFeldmanBarrett · X

Jul 31, 2020 · 2 likes · 44,362 followers View post →

Evidence for a Large-Scale Brain System Supporting Allostasis and Interoception in Humans.

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