... не показывают традиционной для биологических систем зависимости "доза-эффект", что вызывает вопросы. Даже для этого специфичного случая последний метаанализ делает очень осторожный вывод: "The overall quality of evidence was moderate to very low." https://t.co/E0EGwOlJ0b
Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis.
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Jan 2019 – May 2025Where it's discussed
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AI synopsis
What people are saying
The discussions show a strong consensus that widely-used supplements such as glucosamine, chondroitin, and collagen have minimal clinical benefits for osteoarthritis, with users referencing recent meta-analyses and emphasizing evidence-based conclusions. The tone and word choices reflect a shift from skepticism to reliance on scientific evidence, indicating the publication's potential to impact opinions on supplement use.
Most discussions reinforce the study's conclusion that common supplements lack significant long-term benefits for osteoarthritis, showing strong consensus.
Comments demonstrate high interest, with users referencing multiple studies and meta-analyses, discussing specific supplements like collagen, glucosamine, and Boswellia.
Many discussions include detailed critiques of supplement efficacy, referencing scientific evidence, and debating implications, indicating deep engagement.
Contrary to some earlier beliefs in supplement effectiveness, users highlight evidence-based findings, suggesting the publication may influence public and medical perceptions.
Abstract in brief
- The review analyzed 69 studies on 20 different dietary supplements for osteoarthritis, finding that some (like collagen hydrolysate, passion fruit peel extract, curcumin, pycnogenol, and L-carnitine) showed significant pain relief in the short term.
- At medium term, green-lipped mussel extract and undenatured type II collagen provided clinically important pain reduction, but none of the supplements showed long-term benefits.
- Overall, supplements had moderate short-term effects on pain and physical function, with no major safety concerns, though the quality of evidence varied from very low to high.
Top posts
Most liked on X and Bluesky“The most widely used supplements (eg, glucosamine, chondroitin) do not provide a clinically important effect on osteoarthritis” https://t.co/vG5dVlJ4oW “Currently, there is no good evidence to support the use of glucosamine for hip or knee OA..” https://t.co/KBmyJiyBOY
هذه المكملات كحال اي دواء موجود في الصيدلية، اخذها بشكل مبالغ به قد يؤثر على اجهزة الجسم مثل الكبد والكلى لذلك ينصح باستشارة الطبيب قبل اخذ اي من هذه المكملات تمت https://t.co/3h3ch9PJlD
@juliannejtaylor @CaloriesProper @NanciGuestRDPhD @coffeeordie71 The belief in pain relief is big - 30-40% response rate in most trials even in placebo groups! Collagen has been around for a while and still no major trial showing efficacy. Like glucosamine and condroitin... initial hype, but largely ineffective https://t.co/Yz0Pt9357P
@Samuel36916439 Partiendo d la pérdida d peso, ejercicio y una alimentación sin ultraprocesados con aporte pescado y verduras como base, colágeno, vitamina D, C, curcumina y jengibre. #osteoartritis https://t.co/FVlYSYNkTq https://t.co/Ec7B0dzM1J https://t.co/kJOFSabIUe https://t.co/Ek76vkDGQt https://t.co/aXxUQtgDAS
No generan efectos clínicamente importantes sobre el dolor y la función articular en los seguimientos a mediano y largo plazo. https://t.co/HtCF7Hqs2n
All mentions
Top Supplements for Joint Pain Relief Proven by Research
There are three supplements shown to be effective for joint pain based on research. The studies linked include liposomal curcumin, omega-3 fatty acids, and other nutritional options. Short-term benefits are notable, but…
Dietary Supplements for Osteoarthritis: Short-term Pain Relief Insights
This video reviews 69 studies on dietary supplements for osteoarthritis, highlighting some like collagen, passion fruit extract, and curcumin that offer short-term pain relief. It also discusses medium-term benefits and…
クルクミン(ただしデータは少ない) L-カルニチン(ただしデータは少ない) パッションフルーツエキス ウコン根エキス(ただしデータは少ない) ジメチルスルホン ボスウェリアセラタ樹脂エキス https://t.co/qekB698BCE #自分用メモ
Review Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis #passionfruitpeel #arthritis #seasonal https://t.co/wfdtxLxtyZ
@julia_doubleday I used to be very much into heavy weight training and long runs + HIIT. My joints took a beating, whenever I stopped using MSM, chondroiton and high dose MSM, I couldn’t stand the joint pain. My suggestion is those 2 plusmegadoses of MSM. https://t.co/BOg9nIFaht https://t.co/FUaYF9MMbG
@thesneha_ Even latest meta-analysis concluded its long term significance on osteoarthritis is questionable https://t.co/zKfOmpfql5
The results of this study were consistent with a prior 2018 study that looked at over 20 supplements commonly used to treat symptomatic osteoarthritis. Boswellia extract was among the standouts with large effect sizes on pain reduction. https://t.co/tOXH7uMNIZ
2018年のLiuらによるシステマティックレビューでは、"最も広く使用されているサプリメント(例えば、グルコサミン、コンドロイチン)は、変形性関節症に対して臨床的に重要な効果をもたらさない "と結論を出しました。 https://t.co/Z0rkCKPkMX https://t.co/hWfAL5df5n
Passion fruit peel is one natural agent with osteoarthritis benefits. I love putting it in tea. https://t.co/fckRnfxxTT
The results of this study were consistent with a prior 2018 study that looked at over 20 supplements commonly used to treat symptomatic osteoarthritis. Boswellia extract was among the standouts with large effect sizes on pain reduction. https://t.co/tOXH7uMNIZ
@PrimaryCarePAC Right in line with all evidence Dave! https://t.co/Yz0Pt9357P Supplements had no clinically important effects on pain and function at medium-term and long-term follow-ups.
RT @E3Rehab: “The most widely used supplements (eg, glucosamine, chondroitin) do not provide a clinically important effect on osteoarthriti…
RT @IberianCitizen: @Samuel36916439 Partiendo d la pérdida d peso, ejercicio y una alimentación sin ultraprocesados con aporte pescado y ve…
RT @IberianCitizen: @Samuel36916439 Partiendo d la pérdida d peso, ejercicio y una alimentación sin ultraprocesados con aporte pescado y ve…
@Samuel36916439 Partiendo d la pérdida d peso, ejercicio y una alimentación sin ultraprocesados con aporte pescado y verduras como base, colágeno, vitamina D, C, curcumina y jengibre. #osteoartritis https://t.co/FVlYSYNkTq https://t.co/Ec7B0dzM1J https://t.co/kJOFSabIUe https://t.co/Ek76vkDGQt https://t.co/aXxUQtgDAS
RT @E3Rehab: “The most widely used supplements (eg, glucosamine, chondroitin) do not provide a clinically important effect on osteoarthriti…
RT @E3Rehab: “The most widely used supplements (eg, glucosamine, chondroitin) do not provide a clinically important effect on osteoarthriti…
RT @E3Rehab: “The most widely used supplements (eg, glucosamine, chondroitin) do not provide a clinically important effect on osteoarthriti…
“The most widely used supplements (eg, glucosamine, chondroitin) do not provide a clinically important effect on osteoarthritis” https://t.co/vG5dVlJ4oW “Currently, there is no good evidence to support the use of glucosamine for hip or knee OA..” https://t.co/KBmyJiyBOY
Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis - PubMed https://t.co/fckRnffoFL
RT @QuantStrength: ... не показывают традиционной для биологических систем зависимости "доза-эффект", что вызывает вопросы. Даже для этого…
RT @QuantStrength: ... не показывают традиционной для биологических систем зависимости "доза-эффект", что вызывает вопросы. Даже для этого…
... не показывают традиционной для биологических систем зависимости "доза-эффект", что вызывает вопросы. Даже для этого специфичного случая последний метаанализ делает очень осторожный вывод: "The overall quality of evidence was moderate to very low." https://t.co/E0EGwOlJ0b
هذه المكملات كحال اي دواء موجود في الصيدلية، اخذها بشكل مبالغ به قد يؤثر على اجهزة الجسم مثل الكبد والكلى لذلك ينصح باستشارة الطبيب قبل اخذ اي من هذه المكملات تمت https://t.co/3h3ch9PJlD
RT @GYM_EXTREMO: No generan efectos clínicamente importantes sobre el dolor y la función articular en los seguimientos a mediano y largo pl…
RT @DrPalmquist: Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis - PubMed “collagen hydrolysate, pas…
Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis - PubMed “collagen hydrolysate, passion fruit peel extract, Curcuma longa extract, Boswellia serrata extract, curcumin, pycnogenol and L-carnitine)” best effects https://t.co/fckRnffoFL
RT @mackinprof: @CarbAppropriate @NanciGuestRDPhD @juliannejtaylor @coffeeordie71 Peptides absorbed, I would never deny. Skin... ok, but no…
@CarbAppropriate @NanciGuestRDPhD @juliannejtaylor @coffeeordie71 Peptides absorbed, I would never deny. Skin... ok, but not the original point. Joint health, no convincing data, https://t.co/Yz0Pt9357P Muscle - total
@mboyle1959 @CaloriesProper @juliannejtaylor @NanciGuestRDPhD @coffeeordie71 Have a look at this meta https://t.co/Yz0Pt9kFZn and the conclusions
RT @mackinprof: @juliannejtaylor @CaloriesProper @NanciGuestRDPhD @coffeeordie71 The belief in pain relief is big - 30-40% response rate in…
@juliannejtaylor @CaloriesProper @NanciGuestRDPhD @coffeeordie71 The belief in pain relief is big - 30-40% response rate in most trials even in placebo groups! Collagen has been around for a while and still no major trial showing efficacy. Like glucosamine and condroitin... initial hype, but largely ineffective https://t.co/Yz0Pt9357P
@CaloriesProper @juliannejtaylor @NanciGuestRDPhD @coffeeordie71 https://t.co/Yz0Pt9357P no real evidence for efficacy in OA
@juliannejtaylor @NanciGuestRDPhD @coffeeordie71 It’s mostly junk science. Meta-analysis - no effect. https://t.co/Yz0Pt9357P
@juliannejtaylor @SailorLapin @langernutrition Evidence-based answer, no it doesn't https://t.co/Yz0Pt9357P effects transient at best, trivial in magnitude in most cases. Don't waste your money IMO
RT @mackinprof: @JoelProwting @APNMjournal But in-line with recent meta-analysis: https://t.co/Yz0Pt9357P Supplements had no clinically imp…
@JoelProwting @APNMjournal But in-line with recent meta-analysis: https://t.co/Yz0Pt9357P Supplements had no clinically important effects on pain and function at medium-term and long-term follow-ups. Remember glucosamine, chondroitin... #hype>#evidence
No generan efectos clínicamente importantes sobre el dolor y la función articular en los seguimientos a mediano y largo plazo. https://t.co/HtCF7Hqs2n
@madmaxsomm @APNMjournal Supplements had no clinically important effects on pain and function at medium-term and long-term follow-ups. https://t.co/Yz0Pt9357P
@MANUELVISO1 Hay bastante evidencia, metaanálisis incluso ;) https://t.co/9gBnttQ5U5
@brucart @MANUELVISO1 @cescept Te puedes fiar :) https://t.co/9gBnttyuvv
RT @claudiaegl92: The most widely used supplements (eg, glucosamine, chondroitin) do not provide a clinically important effect on osteoarth…
RT @claudiaegl92: The most widely used supplements (eg, glucosamine, chondroitin) do not provide a clinically important effect on osteoarth…
The most widely used supplements (eg, glucosamine, chondroitin) do not provide a clinically important effect on osteoarthritis. Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis https://t.co/8W40Yw7vbu
@Meat_Matter_Pod @CaloriesProper @kevinnbass @AlexFerentinos7 @AlexJLeaf @DavidHealth @mightbeanybody @JenniferSygo @NBCNews @ChrisMasterjohn @ValtsuH https://t.co/4zH2WRstnO Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis: Supplements had no clinically important effects on pain and function at medium-term and long-term follow-ups. (collagen included)
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