October 2018 PMID 29055953

An Open-Label Randomized Multicenter Study Assessing the Noninferiority of a Caffeine-Based Topical Liquid 0.2% versus Minoxidil 5% Solution in Male Androgenetic Alopecia.

Rachita Dhurat, Jill Chitallia, Theodor W May, Ammani M Jayaraaman, Jithendriya Madhukara, Subbu Anandan, Pradyumna Vaidya, Adolf Klenk

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Mentions

90
Peak: 24 in Jun 2025
across 6 sources since Dec 2020

Extended reach

547,797
potential audience

Total likes

8,259

Video views

531,803

Mentions per month

Dec 2020 – Sep 2025

Where it's discussed

  • News46 articles
  • X / Twitter32 posts
  • YouTube4 videos
  • Reddit4 posts
  • Facebook2 posts
  • Blogs2 articles

AI synopsis

What people are saying

The discussions reflect a generally supportive attitude toward the study, often citing it as evidence that caffeine solutions work for alopecia, indicated by phrases like 'this study proves you wrong' and 'it works for alopecia,' which demonstrate active engagement and the desire to inform or challenge others. The tone varies from confident assertions to calls for validation, showing moderate influence and interest in the topic.

AgreementModerate agreement

Most discussions support the idea that the caffeine-based solution is effective for hair loss, reflecting general agreement with the study's findings.

InterestModerate interest

Participants show moderate interest, often referencing the study directly or suggesting its relevance to hair loss treatments.

EngagementHigh engagement

Comments are highly engaged, with many users referencing the research, sharing opinions, and demanding clarification or validation.

ImpactModerate impact

While the discussions influence opinions and spread information, the overall impact remains moderate as they are mostly among individuals already interested in hair loss solutions.

Abstract in brief

  • The study aimed to compare the effectiveness of a caffeine-based topical solution (O2) with the standard minoxidil 5% solution in treating male androgenetic alopecia, and found the caffeine-based solution to be similarly effective.
  • Over 6 months, both treatments increased the percentage of healthy hair follicles (anagen hairs), with minoxidil showing slightly higher improvement, but the difference was small enough to consider the caffeine solution noninferior.
  • The results suggest that a caffeine-based topical liquid could be a viable alternative to minoxidil 5% for men with this type of hair loss, potentially offering more treatment options.]

Top posts

Most liked on X and Bluesky
abuobesity
@abuobesity · X

@_iMarriedPrince @triiadxx heres a study proving you wrong https://t.co/i6tdBaq4Re

Jun 4, 2025 · 16 likes · 298 followers View post →
abuojoruh
@abuojoruh · X

@_iMarriedPrince @triiadxx heres a study proving you wrong https://t.co/i6tdBaq4Re

Jun 4, 2025 · 16 likes · 289 followers View post →
د.ريم النمري
@PhDreem · X

•مستحضرات التجميل ذات فعالية واضحة ومثبتة علمياً في أحيان كثيرة، مع أعراض جانبية أقل✨

Oct 29, 2021 · 8 likes · 5,841 followers View post →
Buğra
@bugrilyus · X

@Aegean_E Güzel derlenmiş bir şey atacağım, çünkü uyku vakti şu anda https://t.co/Q4VojWkmfy

May 15, 2023 · 4 likes · 178 followers View post →
abuobesity
@abuobesity · X

@UniBornB @triiadxx stop spreading misinformation https://t.co/i6tdBaq4Re

Jun 4, 2025 · 2 likes · 298 followers View post →
abuobesity
@abuobesity · X

@_iMarriedPrince @2000ANDTAE @triiadxx here's a study proving you wrong https://t.co/i6tdBaq4Re

Jun 4, 2025 · 2 likes · 298 followers View post →

All mentions

gargoyle
@gargoyle8148 · X

@cgalballing @dannyroddy https://t.co/zGulqcjbxU

Aug 3, 2025 · 21 followers View post →
abuojoruh
@abuojoruh · X

@venusiema @_iMarriedPrince @triiadxx you're just loud and wrong. https://t.co/i6tdBaq4Re

Jun 4, 2025 · 289 followers View post →
abuobesity
@abuobesity · X

@venusiema @_iMarriedPrince @triiadxx you're just loud and wrong. https://t.co/i6tdBaq4Re

Jun 4, 2025 · 298 followers View post →
abuojoruh
@abuojoruh · X

@ahtnamas @UniBornB @triiadxx he's also wrong . topical oils work just as well as minoxidil https://t.co/i6tdBaq4Re

Jun 4, 2025 · 1 like · 289 followers View post →
abuobesity
@abuobesity · X

@ahtnamas @UniBornB @triiadxx he's also wrong . topical oils work just as well as minoxidil https://t.co/i6tdBaq4Re

Jun 4, 2025 · 1 like · 298 followers View post →
abuojoruh
@abuojoruh · X

@Sk8Ghoul @_iMarriedPrince @Harmonie1974 @bavarianswan this is false btw stop spreading misinformation please . it works for alopecia https://t.co/i6tdBaq4Re

Jun 4, 2025 · 289 followers View post →
abuobesity
@abuobesity · X

@Sk8Ghoul @_iMarriedPrince @Harmonie1974 @bavarianswan this is false btw stop spreading misinformation please . it works for alopecia https://t.co/i6tdBaq4Re

Jun 4, 2025 · 298 followers View post →
abuojoruh
@abuojoruh · X

@_iMarriedPrince @Sk8Ghoul this study literally proves you wrong. it works for alopecia https://t.co/i6tdBaq4Re

Jun 4, 2025 · 2 likes · 289 followers View post →
abuobesity
@abuobesity · X

@_iMarriedPrince @Sk8Ghoul this study literally proves you wrong. it works for alopecia https://t.co/i6tdBaq4Re

Jun 4, 2025 · 2 likes · 298 followers View post →
abuobesity
@abuobesity · X

@PhantasticPink @LyricJD9 @n1hilistx @_iMarriedPrince @Larry8743787355 stop lying https://t.co/i6tdBaq4Re

Jun 4, 2025 · 1 like · 298 followers View post →
abuojoruh
@abuojoruh · X

@PhantasticPink @LyricJD9 @n1hilistx @_iMarriedPrince @Larry8743787355 stop lying https://t.co/i6tdBaq4Re

Jun 4, 2025 · 1 like · 289 followers View post →
abuobesity
@abuobesity · X

@_iMarriedPrince @StyleFemD @triiadxx all it takes is a simple google search to prove you wrong https://t.co/i6tdBaq4Re

Jun 4, 2025 · 298 followers View post →
abuojoruh
@abuojoruh · X

@_iMarriedPrince @StyleFemD @triiadxx all it takes is a simple google search to prove you wrong https://t.co/i6tdBaq4Re

Jun 4, 2025 · 289 followers View post →
abuobesity
@abuobesity · X

@PhantasticPink @n1hilistx @_iMarriedPrince @Larry8743787355 this is misinformation https://t.co/i6tdBaq4Re

Jun 4, 2025 · 298 followers View post →
abuojoruh
@abuojoruh · X

@PhantasticPink @n1hilistx @_iMarriedPrince @Larry8743787355 this is misinformation https://t.co/i6tdBaq4Re

Jun 4, 2025 · 289 followers View post →
abuobesity
@abuobesity · X

@_iMarriedPrince here's a study proving you wrong. certain oils quite literally work just as well as monaxadil https://t.co/i6tdBaq4Re

Jun 4, 2025 · 1 like · 298 followers View post →
abuojoruh
@abuojoruh · X

@_iMarriedPrince here's a study proving you wrong. certain oils quite literally work just as well as monaxadil https://t.co/i6tdBaq4Re

Jun 4, 2025 · 1 like · 289 followers View post →
abuobesity
@abuobesity · X

@UniBornB @triiadxx stop spreading misinformation https://t.co/i6tdBaq4Re

Jun 4, 2025 · 2 likes · 298 followers View post →
abuojoruh
@abuojoruh · X

@UniBornB @triiadxx stop spreading misinformation https://t.co/i6tdBaq4Re

Jun 4, 2025 · 2 likes · 289 followers View post →
abuobesity
@abuobesity · X

@_iMarriedPrince @triiadxx heres a study proving you wrong https://t.co/i6tdBaq4Re

Jun 4, 2025 · 16 likes · 298 followers View post →
abuojoruh
@abuojoruh · X

@_iMarriedPrince @triiadxx heres a study proving you wrong https://t.co/i6tdBaq4Re

Jun 4, 2025 · 16 likes · 289 followers View post →
abuobesity
@abuobesity · X

@_iMarriedPrince @Harmonie1974 here's a study proving you wrong https://t.co/i6tdBaq4Re

Jun 4, 2025 · 298 followers View post →
abuojoruh
@abuojoruh · X

@_iMarriedPrince @Harmonie1974 here's a study proving you wrong https://t.co/i6tdBaq4Re

Jun 4, 2025 · 289 followers View post →
abuobesity
@abuobesity · X

@_iMarriedPrince @2000ANDTAE @triiadxx here's a study proving you wrong https://t.co/i6tdBaq4Re

Jun 4, 2025 · 2 likes · 298 followers View post →
abuojoruh
@abuojoruh · X

@_iMarriedPrince @2000ANDTAE @triiadxx here's a study proving you wrong https://t.co/i6tdBaq4Re

Jun 4, 2025 · 2 likes · 289 followers View post →
TheDestroyerofLies
@TheDestroy1344 · X

@hubermanlab @PeterAttiaMD some people say there are some inaccuracies in your hairloss video please watch this https://t.co/HGZ05rzUIN

May 7, 2024 · 16 followers View post →
TheDestroyerofLies
@TheDestroy1344 · X

@hubermanlab @PeterAttiaMD https://t.co/HGZ05rzUIN

May 7, 2024 · 16 followers View post →
VILLIAN
@prismofpain1 · X

@hubermanlab @AdamMGrant Come on Professor at least acknowledge you watched this video Please! . . . . . https://t.co/KUAw1lkc3b

Nov 29, 2023 · 85 followers View post →
VILLIAN
@prismofpain1 · X

@hubermanlab you need to respond to this guy He debunks a lot of your hairloss misinformation video https://t.co/KUAw1lkc3b

Nov 29, 2023 · 85 followers View post →
Buğra
@bugrilyus · X

@Aegean_E Güzel derlenmiş bir şey atacağım, çünkü uyku vakti şu anda https://t.co/Q4VojWkmfy

May 15, 2023 · 4 likes · 178 followers View post →
د.ريم النمري
@PhDreem · X

•مستحضرات التجميل ذات فعالية واضحة ومثبتة علمياً في أحيان كثيرة، مع أعراض جانبية أقل✨

Oct 29, 2021 · 8 likes · 5,841 followers View post →
ysaito
@ysaito8015 · X

へー。カフェイン水溶液が育毛に効果があるかも / An Open-Label Randomized Multicenter Study Assessing the Noninferiority of a Caffeine-Based Topical Liquid 0.2% versus Minoxidil 5% Solution in Male Androgenetic Alopecia https://t.co/GUvr8zX2du

Dec 21, 2020 · 2,709 followers View post →