BMC Biol October 2017 PMID 29078764

An intrinsically disordered linker controlling the formation and the stability of the bacterial flagellar hook.

Clive S Barker, Irina V Meshcheryakova, Alla S Kostyukova, Peter L Freddolino, Fadel A Samatey

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Mentions

Peak: 1 in Dec 2017

across 2 sources since Dec 2017

Extended reach

11,374

potential audience

Total likes

Video views

2,373

Mentions per month

Dec 2017 – Jul 2019

Where it's discussed

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YouTube1 videos

AI synopsis

What people are saying

The discussions highlight the significance of the intrinsically disordered linker in bacterial flagella, with some posters emphasizing its role in stability and motility, referring to it as a 'crucial' or 'key' element, which indicates recognition of the study's importance. The tone varies from neutral acknowledgment to cautious optimism, aligning with the moderate scores across the dimensions.

AgreementModerate agreement

Some discussions recognize the significance of the research, while others are more neutral or cautious in their support.

InterestModerate interest

The social discussions show moderate interest, with participants noting the novel insights into protein flexibility and bacterial motility.

EngagementNeutral engagement

Engagement levels appear average; some posts briefly acknowledge the importance without deep analysis, and others remain relatively superficial.

ImpactModerate impact

Participants see this study as moderately impactful, hinting at future applications or broader biological implications but not emphasizing immediate transformative effects.

Abstract in brief

The text discusses how a specific disordered protein segment, called a linker, is crucial for the formation, stability, and flexibility of the bacterial flagellar hook, which is essential for bacterial motility.
Different bacteria have varying lengths of this linker, and changes or mutations in conserved parts of it can lead to faulty flagella or decreased movement, especially in species like Campylobacter that rotate their flagella at higher speeds.
The study highlights that despite being a disordered region, the linker has a highly specialized role in ensuring the proper assembly and mechanical stability of the flagellum, showing how flexible protein regions can be critical for complex molecular machines.

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All mentions

Disordered Protein Linker Key to Bacterial Flagellar Stability

This work focuses on how a disordered protein segment, known as a linker, is essential for the formation, stability, and flexibility of the bacterial flagellar hook, which is vital for bacterial motility.

BMC · Dec 4, 2017 2,373 views

BMC Biology

@BMCBiology · X

In case you missed it: An intrinsically disordered linker controlling the formation and the stability of the bacterial flagellar hook https://t.co/coVcYYU4xg

Jul 17, 2019 · 9,001 followers View post →