October 2017 PMID 29109686

Ketone Diester Ingestion Impairs Time-Trial Performance in Professional Cyclists.

Jill J Leckey, Megan L Ross, Marc Quod, John A Hawley, Louise M Burke

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Mentions

Peak: 9 in Jun 2019

across 6 sources since Jan 2019

Extended reach

312,059

potential audience

Total likes

4,264

Video views

153,960

Mentions per month

Jan 2019 – Feb 2025

Where it's discussed

X / Twitter35 posts
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Facebook21 posts
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AI synopsis

What people are saying

The overall tone shows strong agreement with the findings, illustrated by phrases like 'confirms previous research' and questions about supplement use in professional cycling, demonstrating both scientific interest and concern for practical implications. The tone and context reflect a recognition of the study’s high relevance and potential influence on sports nutrition debates.

AgreementStrong agreement

Most discussions recognize and support the study's conclusion that ketone diester ingestion impairs cycling performance, as shown by consistent references to the negative effects observed.

InterestModerate interest

The discussions demonstrate moderate interest, with participants referencing related studies, scientific comments, and practical implications of the findings.

EngagementModerate engagement

Participants engage by citing specific experiments, sharing related research, and questioning the broader use of such supplements, indicating thoughtful involvement.

ImpactHigh impact

The conversation underscores the high impact of the study, given its implications for athletic performance and doping considerations, highlighting its significance for sports science.

Abstract in brief

The study found that ingesting a ketone diester before a cycling time trial increased blood ketone levels but impaired performance, reducing race times by about 2%.
This negative effect was linked to gut discomfort and a higher perceived effort during the effort, despite elevated ketone levels.
Overall, consuming this ketone supplement in a carbohydrate-fed state hinders cycling performance in professional athletes rather than enhancing it.

Read the full abstract

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Impact of Ketone Supplements on Cycling Performance and Fat Oxidation

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Dylan Johnson · Sep 9, 2022 103,451 views

Impact of Ketogenic Diet on Cycling Performance and Fuel Utilization

Will Girling, pro cycling nutritionist for EF, discusses ketogenic diets, supplements like HVMN Ketone Ester, and their potential to enhance cycling performance by increasing power output and fat burning during exercise.

CADE Media · Jul 18, 2020 47,702 views

Effectiveness of Ketone Supplements for Athletic Performance

Ketone supplements have gained interest in improving athletic performance, primarily for their potential to enhance energy efficiency. This analysis explores how ketones compare to traditional fuels, the scientific…

Sarah Does Sass · Feb 23, 2025 2,808 views

Dr. Jonathan Little

@DrJonLittle · X

@AdrianSotoMota @AKoutnik @ChrisPalmerMD Although possibly give diester to humans and they lose weight due to GI upset

Apr 12, 2023 · 4 likes · 2,075 followers View post →

南部　博昭(Hiroaki Nanbu)

@Hiroaki_Nanbu · X

RT @Team_inspire: Ketone Diester Ingestion Impairs Time-Trial Performance in Professional Cyclists https://t.co/FsE2evovw0

Nov 18, 2020 · 1 share · 1,641 followers View post →

J-Shira

@Team_inspire · X

Ketone Diester Ingestion Impairs Time-Trial Performance in Professional Cyclists https://t.co/FsE2evovw0

Nov 18, 2020 · 1 share · 4,797 followers View post →

Bertrand Guyot

@bguyot1982 · X

May 29, 2020 · 5 likes · 7,870 followers View post →

Jason Koop

@jasonkoop · X

RT @BSinger10: A few papers on exogenous ketone supplements: https://t.co/e9oKsM3QhG https://t.co/WkcQ96wDkP https://t.co/PovqJDJsL6 ht…

Dec 19, 2019 · 3 shares · 12,897 followers View post →

Andrés Toro Salinas

@andresnauta · X

RT @BSinger10: A few papers on exogenous ketone supplements: https://t.co/e9oKsM3QhG https://t.co/WkcQ96wDkP https://t.co/PovqJDJsL6 ht…

Dec 19, 2019 · 3 shares · 197 followers View post →

Eric Rawson, Ph.D.

@EricRawsonPhD · X

RT @BSinger10: A few papers on exogenous ketone supplements: https://t.co/e9oKsM3QhG https://t.co/WkcQ96wDkP https://t.co/PovqJDJsL6 ht…

Dec 18, 2019 · 3 shares · 7,537 followers View post →

Brett Singer MS,RD,CSSD

@BSinger10 · X

Dec 18, 2019 · 31 likes · 3 shares · 2,815 followers View post →

Hob Gadling

@OliveChirper · X

@1953Trevor @geoffreywoo @janvyjidak @UniofOxford @hvmn It's actually less doping than glucose, since glucose actually improves performance whereas exogenous ketones (esters or salts) pretty consistently don't https://t.co/IMFqscgCwQ https://t.co/hIGNvZqHEu https://t.co/uu3lcwMwnx https://t.co/N3pYSpS3q5 https://t.co/CjLBN9qmbK

Aug 20, 2019 · 1 like · 1 share · 275 followers View post →

Guillem Vizcaíno

@vizcaphysiology · X

RT @jwhitfie: New in @MSSEonline - No additional benefit to coingestion of carbohydrate and ketone on 10km running performance https://t.…

Aug 1, 2019 · 11 shares · 193 followers View post →

@mischnachtreisr@mastodon.opencloud.lu

@mischnachtreisr · X

RT @XphysNerd: Why are TDF teams divided over the use of a supplement which has beeen shown to impair or not affect performance? #TDF2019 #…

Jul 21, 2019 · 1 share · 472 followers View post →

Tony Ciccone

@XphysNerd · X

Why are TDF teams divided over the use of a supplement which has beeen shown to impair or not affect performance? #TDF2019 #TourdeFrance https://t.co/kawK3XULii https://t.co/nwjmg4xsU1 https://t.co/X6rsoPrQly https://t.co/c5I7xQ9kYf

Jul 19, 2019 · 3 likes · 1 share · 179 followers View post →

Gommaar D'Hulst

@Gommaar · X

En dit komt van de meest prominente coach van het land?

Jul 17, 2019 · 2 likes · 1,320 followers View post →

Konstantinos Prokopidis

@KostasProko · X

RT @jwhitfie: New in @MSSEonline - No additional benefit to coingestion of carbohydrate and ketone on 10km running performance https://t.…

Jul 12, 2019 · 11 shares · 1,490 followers View post →

Kevin Tipton

@proftipper · X

RT @jwhitfie: New in @MSSEonline - No additional benefit to coingestion of carbohydrate and ketone on 10km running performance https://t.…

Jul 12, 2019 · 11 shares · 18,206 followers View post →

Jill Leckey

@Jill_leckey · X

RT @jwhitfie: New in @MSSEonline - No additional benefit to coingestion of carbohydrate and ketone on 10km running performance https://t.…

Jul 12, 2019 · 11 shares · 960 followers View post →

Franck RENIMEL

@FranckRenimel · X

RT @EmmanuelBrunet: Je crois que c’est clair... Ketone Diester Ingestion Impairs Time-Trial Performance in Professional Cyclists https://t.…

Jun 18, 2019 · 2 shares · 457 followers View post →

Jeroen Swart

@JeroenSwart · X

RT @jwhitfie: New in @MSSEonline - No additional benefit to coingestion of carbohydrate and ketone on 10km running performance https://t.…

Jun 18, 2019 · 11 shares · 11,493 followers View post →

Mike Ormsbee, PhD

@mikeormsbee · X

RT @jwhitfie: New in @MSSEonline - No additional benefit to coingestion of carbohydrate and ketone on 10km running performance https://t.…

Jun 17, 2019 · 11 shares · 4,539 followers View post →

Facundo Ahumada

@FAhumadaCordoba · X

RT @jwhitfie: New in @MSSEonline - No additional benefit to coingestion of carbohydrate and ketone on 10km running performance https://t.…

Jun 17, 2019 · 11 shares · 859 followers View post →

Mitch Naughton

@Mitch_Naughton_ · X

RT @jwhitfie: New in @MSSEonline - No additional benefit to coingestion of carbohydrate and ketone on 10km running performance https://t.…

Jun 17, 2019 · 11 shares · 1,883 followers View post →

Trent Stellingwerff, PhD / CSEP-CEP / FACSM / ChPC

@TStellingwerff · X

RT @jwhitfie: New in @MSSEonline - No additional benefit to coingestion of carbohydrate and ketone on 10km running performance https://t.…

Jun 17, 2019 · 11 shares · 23,120 followers View post →

Matthew Black

@matthewianblack · X

RT @jwhitfie: New in @MSSEonline - No additional benefit to coingestion of carbohydrate and ketone on 10km running performance https://t.…

Jun 17, 2019 · 11 shares · 554 followers View post →

Javier Gonzalez

@Gonzalez_JT · X

RT @jwhitfie: New in @MSSEonline - No additional benefit to coingestion of carbohydrate and ketone on 10km running performance https://t.…

Jun 17, 2019 · 11 shares · 10,198 followers View post →

Jamie Whitfield, PhD

@jwhitfie · X

Jun 17, 2019 · 29 likes · 11 shares · 2,343 followers View post →

Chris Harnish, PhD

@Go1MoreMile · X

RT @GregoireMillet1: Interesting work by @JohnAHawley & @LouiseMBurke in @FrontPhysiol Ketone Diester Ingestion Impairs Time-Trial Perfo…

May 30, 2019 · 3 shares · 440 followers View post →

Jeroen Swart

@JeroenSwart · X

RT @GregoireMillet1: Interesting work by @JohnAHawley & @LouiseMBurke in @FrontPhysiol Ketone Diester Ingestion Impairs Time-Trial Perfo…

May 30, 2019 · 3 shares · 11,493 followers View post →

Martijn Doekes

@Doekes · X

@laurenstendam here you go: RT @jasonkoop: 'Ketone ingestion induces hyperketonemia in elite professional cyclists when in a carbohydrate fed state, and impairs performance of a cycling TT lasting ~50 min.' https://t.co/8LPY96z4P7

May 30, 2019 · 1 like · 100 followers View post →

Jason Koop

@jasonkoop · X

'Ketone ingestion induces hyperketonemia in elite professional cyclists when in a carbohydrate fed state, and impairs performance of a cycling TT lasting ~50 min.' https://t.co/Gjyba596UO

May 30, 2019 · 7 likes · 12,897 followers View post →

Tadej Debevec

@DebevecTadej · X

RT @GregoireMillet1: Interesting work by @JohnAHawley & @LouiseMBurke in @FrontPhysiol Ketone Diester Ingestion Impairs Time-Trial Perfo…

May 30, 2019 · 3 shares · 3,810 followers View post →

Gregoire Millet

@GregoireMillet1 · X

Interesting work by @JohnAHawley & @LouiseMBurke in @FrontPhysiol Ketone Diester Ingestion Impairs Time-Trial Performance in Professional Cyclists https://t.co/HB5i78QToR

May 30, 2019 · 9 likes · 3 shares · 5,780 followers View post →

Jérémy gouillon

@jeremygouillon · X

RT @EmmanuelBrunet: Je crois que c’est clair... Ketone Diester Ingestion Impairs Time-Trial Performance in Professional Cyclists https://t.…

May 30, 2019 · 2 shares · 251 followers View post →

Emmanuel Brunet

@EmmanuelBrunet · X

Je crois que c’est clair... Ketone Diester Ingestion Impairs Time-Trial Performance in Professional Cyclists https://t.co/N8dYME4cjo

May 30, 2019 · 4 likes · 2 shares · 3,233 followers View post →

Stationery

@stationerybest · X

Ketone Diester Ingestion Impairs Time-Trial Performance in Professional Cyclists. https://t.co/PGblwyk9HK

Jan 17, 2019 · 696 followers View post →

Stationery

@stationerybest · X

Ketone Diester Ingestion Impairs Time-Trial Performance in Professional Cyclists. https://t.co/PGblwyk9HK

Jan 3, 2019 · 696 followers View post →

Ketone Diester Ingestion Impairs Time-Trial Performance in Professional Cyclists.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Impact of Ketone Supplements on Cycling Performance and Fat Oxidation

Impact of Ketogenic Diet on Cycling Performance and Fuel Utilization

Effectiveness of Ketone Supplements for Athletic Performance