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N Engl J Med November 2017 PMID 29117490

Mechanical or Biologic Prostheses for Aortic-Valve and Mitral-Valve Replacement.

Andrew B Goldstone, Peter Chiu, Michael Baiocchi, Bharathi Lingala, William L Patrick, Michael P Fischbein, Y Joseph Woo

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Mentions

14
Peak: 2 in Nov 2017
across 3 sources since Nov 2017

Extended reach

64,047
potential audience

Total likes

3

Video views

62,471

Mentions per month

Nov 2017 – Nov 2025

Where it's discussed

  • News11 articles
  • YouTube2 videos
  • X / Twitter1 posts

AI synopsis

What people are saying

The overall tone reflects moderate interest in the topic of prosthetic choices, with mentions of 'biological prostheses' and 'surgical devices,' but the posts lack detailed insights or strong viewpoints, demonstrating a tentative engagement with the publication's content.

AgreementNeither agree nor disagree

The discussions do not strongly agree or disagree but acknowledge the topic of biological versus mechanical prostheses.

InterestModerate interest

Participants show moderate curiosity, mentioning relevant concepts like prosthetic types and surgical devices, but without deep enthusiasm.

EngagementNeutral engagement

There is minimal detailed analysis or elaboration, indicating a surface-level engagement.

ImpactNeutral impact

The comments suggest awareness but do not indicate significant influence or change prompted by the publication.

Abstract in brief

  • Biologic prostheses are increasingly used for aortic and mitral valve replacements in California (from 11.5% to over 50%), but there is limited evidence supporting this trend.
  • For younger patients (ages 45-54 with aortic valves and 40-49 with mitral valves), biologic prostheses are associated with higher 15-year mortality compared to mechanical ones, though this difference is not seen in older age groups.
  • Patients with biologic valves experience higher reoperation rates, and mechanical valves are linked to increased bleeding and stroke incidences in certain age groups.
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Top posts

Most liked on X and Bluesky
MY@MD.,PhD.
@MD_fuk · X

70歳までの患者の僧帽弁置換術 55歳までの患者の大動脈弁置換術 については、生体弁より機械弁を用いたほうが有利。 https://t.co/UuFzCbIl1K

Feb 17, 2019 · 1 like · 1,467 followers View post →

All mentions

MY@MD.,PhD.
@MD_fuk · X

70歳までの患者の僧帽弁置換術 55歳までの患者の大動脈弁置換術 については、生体弁より機械弁を用いたほうが有利。 https://t.co/UuFzCbIl1K

Feb 17, 2019 · 1 like · 1,467 followers View post →
Boskovski Gleason Current Therapeutic Options in Aortic Stenosis ...
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doi: 10.1056/NEJMoa1202277 review and meta-analysis. Ann Cardiothorac Surg ... NEJMoa1613792 Fremes SE. Early and late outcomes following aortic root ...

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2017, 377:1847-57. 10.1056/NEJMoa1613792 3. Malvindi PG, Bifulco O, Berretta P, et al.: The enhanced recovery after surgery approach in heart valve surgery ...

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https://doi.org/10.1056/NEJMoa1613792 patients aged 50 to 69 years. JAMA 312:1323–1329, 2014. https://doi. 24. Gersak B, Fischlein T, Folliguet TA, et al ...

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Ehaf 194 | PDF | Heart | Cardiovascular System
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... 10.1056/NEJMoa1814052. Slovenian Society of Cardiology, Matjaž Bunc; Spain ... NEJMoa1613792 et al. Transcatheter or surgical aortic valve implantation ...

Dec 17, 2025 View →
Bentall Similar Article | PDF | Myocardial Infarction | Heart
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doi: 10.1056/ doi: 10.1016/j.jtcvs.2010.07.033 NEJMoa1613792 11. Etz CD, Girrbach FF, von Aspern K, Battellini R, Dohmen P, Hoyer A, 29. Byrne JG ...

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1 s2.0 S2590006424002552 Main | PDF | Tissue Engineering ...
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377 (2017) 1847–1857, https://doi.org/10.1056/ (2019) 211–268, https://doi.org/10.1016/j.progpolymsci.2018.12.003. NEJMoa1613792. [43] A.G. Kidane, G ...

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Chauvette Et Al. - 2021 - Contemporary Review of the Ross ...
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doi:10.1056/NEJMoa1613792. ments after valve replacements in bicuspid aortic valve disease: 16. Bourguignon T, Lhommet P, El Khoury R, et al ...

Nov 28, 2025 View →
Mechanical surgical valves superior to bioprosthetic valves in mortality
News

Sources/Disclosures. Source: Goldstone AB, et al. N Engl J Med. 2017;doi:10.1056/NEJMoa1613792.

Nov 8, 2017 View →
Mekanisk klaff kopplas till längre liv - Dagens Medicin
News

Överlevnaden verkar vara bättre med en mekanisk hjärtklaffprotes än biologiska varianter hos relativt unga patienter, ...

Nov 8, 2017 View →