Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct.
Raul G Nogueira, Ashutosh P Jadhav, Diogo C Haussen, Alain Bonafe, Ronald F Budzik, Parita Bhuva, Dileep R Yavagal, Marc Ribo, Christophe Cognard, Ricardo A Hanel, Cathy A Sila, Ameer E Hassan, Monica Millan, Elad I Levy, Peter Mitchell
January 2018 N Engl J MedSynopsis of Social media discussions
Discussions emphasize the groundbreaking nature of extending thrombectomy windows, citing specific trials like DAWN and DEFUSE-3, and using emphatic expressions such as 'stunning' and 'revolutionary,' which reflect high interest and acknowledgment of the publication's potential impact.
Agreement
Strong agreementMost discussions strongly support the findings and implications of the publication, highlighting its revolutionary impact on stroke treatment.
Interest
High level of interestPosts demonstrate high curiosity and enthusiasm, referencing key trials like DAWN and DEFUSE-3, and discussing the extended window for thrombectomy.
Engagement
High engagementMany discussions delve into trial details, imaging techniques, and clinical implications, showing deep engagement with the subject matter.
Impact
High level of impactThe consensus indicates that this publication could significantly alter stroke management practices worldwide.
Social Mentions
YouTube
3 Videos
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352,236
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13,305
Extended Reach
611,164
Social Features
305
Timeline: Posts about article
Top Social Media Posts
SVIN Research Registry
Thrombectomy 6-24 Hours after #Stroke with a Mismatch btw Deficit & Infarct https://t.co/vNqm16lwyL Celebrating #WorldStrokeDay2021 with this classic, the DAWN trial. Raul Nogueira, @TudorGJovin @AshuPJadhav @DiogoHaussen @dyavagal @dliebesk @AmeerEHassan @marcriboj @svinsociety https://t.co/Sfp8sdfKHI
view full post
Andrew Althouse
3. the DAWN trial is a favorite of mine for introducing the concept of adaptive trials in a relatively gentle, digestible way:
https://t.co/SlPEiePEYX
view full post
Gray Moonen
2. Stroke care has fundamentally changed. Mechanical thrombectomy is now, in many centres standard of care and I was lucky to do two weeks with @albertjin at @KingstonHSC to see this life-saving treatment: https://t.co/8Qui5VYtIa
view full post
Neha Dangayach MD MSCR FAAN FANA FCCP FCCM FNCS
#chestchat T1: #Stroke: Thrombectomy is the gold standard for ELVO #stroke https://t.co/4xxNGZNnBO
Dawn and Defuse-3: window extended to 24 hours for thrombectomy https://t.co/7qEIrtYs2y
Extend tpa window to 9 hours? https://t.co/Ux4rTEIwUJ
view full post
J Gordon Boyd
@dwmessenger @TheSGEM If you're allowing non-EM people to chime in on topics they might think relevant to your work, I think the DAWN trial (endovascular therapy for acute stroke 6-24h after symptom onset) revolutionized practice. Wake up strokes are now an emergency! https://t.co/fdZdI9VLTl
view full post
Posts referencing the article
Advances in Thrombectomy for Ischemic Stroke Beyond 6 Hours
Trials show that endovascular thrombectomy within 6 hours benefits stroke patients; new research explores outcomes beyond this window, highlighting recent findings on treatment time extensions.
January 4, 2018
10,089 views
Future Perspectives on Ischemic Stroke Treatment and Trials
This episode discusses Dr. Heitor Alves's work with MR Clean and explores upcoming trials in ischemic stroke treatment, including recent studies on intraarterial intervention and potential advances in patient outcomes.
January 30, 2019
810 views
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Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct https://t.co/6AFeW573Ri
view full postJanuary 23, 2025
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江川悟史 | Satoshi Egawa, MD, PhD, FNCS
@Satoshi_Egawa (Twitter)RT @Neurocrit_univ: 急性虚血性脳卒中と神経集中治療15
view full postAugust 27, 2024
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Neurocritical Care University
@Neurocrit_univ (Twitter)急性虚血性脳卒中と神経集中治療15
view full postAugust 25, 2024
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Pharmacy Podcast Network
@PharmacyPodcast (Twitter)RT @PharmacyToDose:
view full postMarch 21, 2024
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Pharmacy To Dose: The Critical Care Podcast
@PharmacyToDose (Twitter)March 20, 2024
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Pharmacy To Dose: The Critical Care Podcast
@PharmacyToDose (Twitter)March 18, 2024
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Хранитель реальности
@KosterNews (Twitter)@momentovmori 1. Диссекция 2. Доказанных методов профилактики инсультов вообще нет, только вторичная. 3. Скорее наоборот, тромболизис в 4.5 часа, а реканализация - 24 часа https://t.co/o1UBw574iG
view full postDecember 10, 2023
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Ruslan Oliinyk
@OliinykMD (Twitter)52 in 52 - #39: DAWN - Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct https://t.co/ygAeX3KWRH
view full postSeptember 3, 2023
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Saad
@asbeutah1 (Twitter)@AANmember Here are a couple of massive trials that show just how stunning thrombolectomy is (major shoutout to all the neurointerventionalists) DAWN trial (doi: 10.1056/NEJMoa1706442) ANGEL-ASPECT trial (doi: 10.1056/NEJMoa2213379) SELECT 2 trial (doi: 10.1056/NEJMoa2214403) https://t.co/XhvgGGbwu5
view full postJuly 29, 2023
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Derek Smith
@proton_spin (Twitter)2/ Major stroke trials using CT/MR perfusion DAWN 2018 https://t.co/AAXsrhabFU DEFUSE-3 2018 https://t.co/NSep3zFxKL EXTEND 2019 https://t.co/Lz8ww9uX0a
view full postFebruary 20, 2022
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J
@JuanCossmic (Twitter)RT @SeeFisch: WOW! WOW!! WOW!! WOW!!! Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct | NEJM ht…
view full postFebruary 12, 2022
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Francis Deng, MD
@francisdeng (Twitter)In the DAWN trial, an inclusion criterion was ICA or MCA-M1 occlusion. M1-M2 junction was defined by the bifurcation. Some probably didn't get the memo: there were 5 patients enrolled (out of 206) that the core lab judged to actually have M2 occlusions. https://t.co/0xVvkwHFax https://t.co/s4HsOesqfF
view full postNovember 26, 2021
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IL
@italolinfante (Twitter)RT @SVINRegistry: Thrombectomy 6-24 Hours after #Stroke with a Mismatch btw Deficit & Infarct https://t.co/vNqm16lwyL Celebrating #WorldStr…
view full postNovember 16, 2021
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@mohammed_moneim (Twitter)RT @SVINRegistry: Thrombectomy 6-24 Hours after #Stroke with a Mismatch btw Deficit & Infarct https://t.co/vNqm16lwyL Celebrating #WorldStr…
view full postNovember 5, 2021
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Carla Vera
@Carlahvc (Twitter)RT @SVINRegistry: Thrombectomy 6-24 Hours after #Stroke with a Mismatch btw Deficit & Infarct https://t.co/vNqm16lwyL Celebrating #WorldStr…
view full postOctober 30, 2021
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inbra
@hitoyoshi11 (Twitter)Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct | NEJM https://t.co/jY1tZHLWns
view full postOctober 29, 2021
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NEUROLOGY
@Neurology (Twitter)RT @SVINRegistry: Thrombectomy 6-24 Hours after #Stroke with a Mismatch btw Deficit & Infarct https://t.co/vNqm16lwyL Celebrating #WorldStr…
view full postOctober 29, 2021
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UPittStroke
@PittStroke (Twitter)RT @SVINRegistry: Thrombectomy 6-24 Hours after #Stroke with a Mismatch btw Deficit & Infarct https://t.co/vNqm16lwyL Celebrating #WorldStr…
view full postOctober 29, 2021
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Pratiek
@drshahpratik74 (Twitter)RT @SVINRegistry: Thrombectomy 6-24 Hours after #Stroke with a Mismatch btw Deficit & Infarct https://t.co/vNqm16lwyL Celebrating #WorldStr…
view full postOctober 29, 2021
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Shahram Majidi, MD
@MajidiShahram (Twitter)RT @SVINRegistry: Thrombectomy 6-24 Hours after #Stroke with a Mismatch btw Deficit & Infarct https://t.co/vNqm16lwyL Celebrating #WorldStr…
view full postOctober 29, 2021
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TESLA Stroke Trial
@TESLATrial (Twitter)RT @SVINRegistry: Thrombectomy 6-24 Hours after #Stroke with a Mismatch btw Deficit & Infarct https://t.co/vNqm16lwyL Celebrating #WorldStr…
view full postOctober 29, 2021
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Thanakit Pongpitakmetha, MD, MSc (getcud)
@getcud (Twitter)RT @SVINRegistry: Thrombectomy 6-24 Hours after #Stroke with a Mismatch btw Deficit & Infarct https://t.co/vNqm16lwyL Celebrating #WorldStr…
view full postOctober 29, 2021
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María A. Moro
@MariAngelesMoro (Twitter)RT @SVINRegistry: Thrombectomy 6-24 Hours after #Stroke with a Mismatch btw Deficit & Infarct https://t.co/vNqm16lwyL Celebrating #WorldStr…
view full postOctober 29, 2021
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Mehdi Bouslama, MD, MSc
@BouslamaMd (Twitter)RT @SVINRegistry: Thrombectomy 6-24 Hours after #Stroke with a Mismatch btw Deficit & Infarct https://t.co/vNqm16lwyL Celebrating #WorldStr…
view full postOctober 29, 2021
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Ameer E. Hassan
@AmeerEHassan (Twitter)RT @SVINRegistry: Thrombectomy 6-24 Hours after #Stroke with a Mismatch btw Deficit & Infarct https://t.co/vNqm16lwyL Celebrating #WorldStr…
view full postOctober 29, 2021
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WINN
@WomenInNeuroIR (Twitter)RT @SVINRegistry: Thrombectomy 6-24 Hours after #Stroke with a Mismatch btw Deficit & Infarct https://t.co/vNqm16lwyL Celebrating #WorldStr…
view full postOctober 29, 2021
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Juan M. Arredondo
@RcJuanMaa (Twitter)RT @SVINRegistry: Thrombectomy 6-24 Hours after #Stroke with a Mismatch btw Deficit & Infarct https://t.co/vNqm16lwyL Celebrating #WorldStr…
view full postOctober 29, 2021
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Thanh Nguyen
@NguyenThanhMD (Twitter)RT @SVINRegistry: Thrombectomy 6-24 Hours after #Stroke with a Mismatch btw Deficit & Infarct https://t.co/vNqm16lwyL Celebrating #WorldStr…
view full postOctober 29, 2021
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Stroke AHA/ASA
@StrokeAHA_ASA (Twitter)RT @SVINRegistry: Thrombectomy 6-24 Hours after #Stroke with a Mismatch btw Deficit & Infarct https://t.co/vNqm16lwyL Celebrating #WorldStr…
view full postOctober 29, 2021
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Dileep R. Yavagal
@dyavagal (Twitter)RT @SVINRegistry: Thrombectomy 6-24 Hours after #Stroke with a Mismatch btw Deficit & Infarct https://t.co/vNqm16lwyL Celebrating #WorldStr…
view full postOctober 29, 2021
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SVIN
@svinsociety (Twitter)RT @SVINRegistry: Thrombectomy 6-24 Hours after #Stroke with a Mismatch btw Deficit & Infarct https://t.co/vNqm16lwyL Celebrating #WorldStr…
view full postOctober 29, 2021
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SVIN Research Registry
@SVINRegistry (Twitter)Thrombectomy 6-24 Hours after #Stroke with a Mismatch btw Deficit & Infarct https://t.co/vNqm16lwyL Celebrating #WorldStrokeDay2021 with this classic, the DAWN trial. Raul Nogueira, @TudorGJovin @AshuPJadhav @DiogoHaussen @dyavagal @dliebesk @AmeerEHassan @marcriboj @svinsociety https://t.co/Sfp8sdfKHI
view full postOctober 29, 2021
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Andrew Althouse
@ADAlthousePhD (Twitter)@SolomonKurz So these may be a little niche/specific to my own interests, but for your consideration...the DAWN trial (https://t.co/SlPEiePEYX) has a very nice Supplemental appendix describing the whole trial design and model:
view full postMarch 15, 2021
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José Luis Santiago
@JLSantiagoG (Twitter)menor deterioro posterior neurológico y no hubo diferencia en la frecuencia de hemorragia intracerebral entre los 2 grupos. Sin embargo, la mortalidad a 90 días fue casi la misma entre los 2 grupos. DOI: 10.1056/NEJMoa1706442 DOI: 10.1186/s12883-019-1428-x https://t.co/6MBbpAy7iT
view full postMarch 6, 2021
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CIRSE European Trainee Forum
@ETF_IRtrainees (Twitter)Part II of important thrombectomy studies Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit an Infarct (DAWN) https://t.co/Ye9fVbsDiU #topicofthemonth #neurointervention https://t.co/FQkbL0gnW8
view full postMarch 4, 2021
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Protik Islam-Jakobsson
@ikitorp (Twitter)RT @ADAlthousePhD: 3. the DAWN trial is a favorite of mine for introducing the concept of adaptive trials in a relatively gentle, digestibl…
view full postJanuary 15, 2021
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Andrew Althouse
@ADAlthousePhD (Twitter)3. the DAWN trial is a favorite of mine for introducing the concept of adaptive trials in a relatively gentle, digestible way: https://t.co/SlPEiePEYX
view full postJanuary 14, 2021
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J Gordon Boyd
@jgordonboyd (Twitter)@dwmessenger @TheSGEM If you're allowing non-EM people to chime in on topics they might think relevant to your work, I think the DAWN trial (endovascular therapy for acute stroke 6-24h after symptom onset) revolutionized practice. Wake up strokes are now an emergency! https://t.co/fdZdI9VLTl
view full postApril 23, 2020
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Jessica Smith
@Jessica28997812 (Twitter)Learned that the DAWN Trial changed the game in stroke treatment. #cincyai https://t.co/xokvNeUWoY
view full postApril 3, 2020
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Binod Wagle
@binodbinodwagle (Twitter)DAWN trial helped unfortunate stroke patient with hope for better life: Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct | NEJM https://t.co/9PMUxYYbbq #UMKCRCT
view full postFebruary 5, 2020
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Doctor Gold
@yourdoctorgold (Twitter)@LactatedRingers It’s not a perfect answer but 50% are functionally independent at 90 days where only 13% of the control group (tPA) were. https://t.co/D6XrXxrPYb
view full postFebruary 2, 2020
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Mahmoud Alsomali
@mahmoud_427 (Twitter)RT @drdangayach: #chestchat T1: #Stroke: Thrombectomy is the gold standard for ELVO #stroke https://t.co/4xxNGZNnBO Dawn and Defuse-3: wind…
view full postDecember 19, 2019
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Chris Carroll MD
@ChrisCarrollMD (Twitter)RT @drdangayach: #chestchat T1: #Stroke: Thrombectomy is the gold standard for ELVO #stroke https://t.co/4xxNGZNnBO Dawn and Defuse-3: wind…
view full postDecember 19, 2019
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Neha Dangayach MD MSCR FAAN FANA FCCP FCCM FNCS
@drdangayach (Twitter)#chestchat T1: #Stroke: Thrombectomy is the gold standard for ELVO #stroke https://t.co/4xxNGZNnBO Dawn and Defuse-3: window extended to 24 hours for thrombectomy https://t.co/7qEIrtYs2y Extend tpa window to 9 hours? https://t.co/Ux4rTEIwUJ
view full postDecember 19, 2019
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Philippe Violon
@docteursante (Twitter)En cas d'AVC, pouvoir déboucher mécaniquement une artère cérébrale permet de faire passer le % de patients indépendants après 3 mois de 13 à 49% ! Une révolution. https://t.co/duHEiJWYmA #urgences #sante
view full postDecember 10, 2019
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Kaishauna Guidry, MD, HMDC
@DrMamaKai (Twitter)RT @PrasannaTadi: @DrMamaKai @IDdocAdi @iamritu @Mummin8r @DrSuperSalty @GermHunterMD @DrPoorman @Vilavaite @StSenka @WaelBarsoumMD @spiceb…
view full postAugust 31, 2019
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Dr. Prasanna Tadi M.D, FAAN, FAHA, Coach, Speaker,
@PrasannaTadi (Twitter)@DrMamaKai @IDdocAdi @iamritu @Mummin8r @DrSuperSalty @GermHunterMD @DrPoorman @Vilavaite @StSenka @WaelBarsoumMD @spiceboxtravels @nursekelsey @AboutPediatrics @empathsupreme @KarenSibertMD @IAmDrIbrahim @NaanDerthaal @cardiojaydoc02 @biljana_parapid @KaraPepperMD https://t.co/SDPVsGSuzG
view full postAugust 31, 2019
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SCCM SE Region
@SCCMSE (Twitter)RT @SummitCritCare: Dr. Nogueira led the @NEJM #DawnTrial showing remarkable benefits for stroke therapy 6-24 hours after onset #CCS19 ht…
view full postApril 18, 2019
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Aarti Sarwal, FNCS, FAAN, FCCM, RPNI, Professor
@aartisarwal (Twitter)RT @SummitCritCare: Dr. Nogueira led the @NEJM #DawnTrial showing remarkable benefits for stroke therapy 6-24 hours after onset #CCS19 ht…
view full postApril 18, 2019
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Greg Martin
@gsmartinmd (Twitter)RT @SummitCritCare: Dr. Nogueira led the @NEJM #DawnTrial showing remarkable benefits for stroke therapy 6-24 hours after onset #CCS19 ht…
view full postApril 18, 2019
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Critical Care Summit
@SummitCritCare (Twitter)Dr. Nogueira led the @NEJM #DawnTrial showing remarkable benefits for stroke therapy 6-24 hours after onset #CCS19 https://t.co/sEifqzx87m https://t.co/V2d2zwHzPO
view full postApril 18, 2019
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Jawad Khalifeh, MD
@jkhalifeh_md (Twitter)RT @ADAlthousePhD: @laure_wynants DAWN was a really cool trial design that had provisions for adaptive enrichment (which were not needed) a…
view full postApril 5, 2019
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Andrew Althouse
@ADAlthousePhD (Twitter)@laure_wynants DAWN was a really cool trial design that had provisions for adaptive enrichment (which were not needed) and early stopping (which did happen because the treatment was hugely effective): https://t.co/g5lbxVbJ6H
view full postApril 5, 2019
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Daniel Ricotta, MD, SFHM
@DanielRicottaMD (Twitter)RT @BIDMC_IM: @DanielRicottaMD @zahirkanjee @BIDMChealth @bidhospitalists @JAMA_current @rbganatra @BostonChiefs @NEJM @zahirkanjee @bidhos…
view full postMarch 29, 2019
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BIDMC IM Residency
@BIDMC_IM (Twitter)@DanielRicottaMD @zahirkanjee @BIDMChealth @bidhospitalists @JAMA_current @rbganatra @BostonChiefs @NEJM @zahirkanjee @bidhospitalists - pursue thrombectomy for select patients with acute stroke for 6-24 hrs out of last known well https://t.co/jA1AdU7GRm
view full postMarch 29, 2019
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Gray Moonen
@GrayMoonen (Twitter)2. Stroke care has fundamentally changed. Mechanical thrombectomy is now, in many centres standard of care and I was lucky to do two weeks with @albertjin at @KingstonHSC to see this life-saving treatment: https://t.co/8Qui5VYtIa
view full postMarch 28, 2019
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Ahmed_Ak97
@ahmed_ak97 (Twitter)This article suggests #thrombectomy as a procedure to be performed on #stroke patients 6-24hrs after the onset. The disability outcome has been attenuated in the group who received thrombectomy and standard care versus standard care alone #biom4180 https://t.co/tfCCuhrUuo
view full postMarch 11, 2019
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Robbie Paulsen
@robbiepaulsen (Twitter)@SamMarek2 #cincyai DAWN Trial used MRI or CTP for pts with last known well w/in 6-24 hours and a large vessel occlusion. Thrombectomy in pts with large salvageable territory reduced disability (49 vs 13% functional independence at 90 days) but not mortality. https://t.co/GCyzHYnTRY
view full postMarch 10, 2019
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Almansour
@malmansour81 (Twitter)RT @DanyaKhoujah: Neuro lit updates w @MDmiamimike #RMWC19 DAWN and DIFFUSE-3: extending the window for revascularization in stroke w/ evid…
view full postFebruary 24, 2019
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Maite Huisintveld (she/her)
@Maiteanna (Twitter)RT @DanyaKhoujah: Neuro lit updates w @MDmiamimike #RMWC19 DAWN and DIFFUSE-3: extending the window for revascularization in stroke w/ evid…
view full postFebruary 24, 2019
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Dr. Danya Khoujah
@DanyaKhoujah (Twitter)Neuro lit updates w @MDmiamimike #RMWC19 DAWN and DIFFUSE-3: extending the window for revascularization in stroke w/ evidence of mismatch on imaging up to 24 h https://t.co/OfcvjCcj1Y https://t.co/LXhnHCU0w2 #FOAMed @RockyMtnEM
view full postFebruary 24, 2019
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GrupoDDM
@Grupo_DDM (Twitter)Improving Outcomes in Stroke https://t.co/9LAZkVuspO vía @YouTube
view full postFebruary 21, 2019
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Dr Michael JT Brooks
@michaeljtbrooks (Twitter)For acute ischaemic stroke patients, going clot-fishing is looking like the way forward. In this paper, patients with a large perfusion defect but smaller infarct did well from thrombectomy. CT perfusion head > thrombectomy = New gold standard? https://t.co/z0pKHh64la
view full postJanuary 16, 2019
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movedoc
@movedoc (Twitter)Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct | NEJM https://t.co/PwWLFWeK4Q
view full postJanuary 2, 2019
Abstract Synopsis
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