Lancet February 2018 PMID 29221645

Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial.

Michael Ej Lean, Wilma S Leslie, Alison C Barnes, Naomi Brosnahan, George Thom, Louise McCombie, Carl Peters, Sviatlana Zhyzhneuskaya, Ahmad Al-Mrabeh, Kieren G Hollingsworth, Angela M Rodrigues, Lucia Rehackova, Ashley J Adamson, Falko F Sniehotta, John C Mathers

Mentions

555
Peak: 7 in Jan 2024
across 6 sources since Jan 2019

Extended reach

847,680
potential audience

Total likes

670

Video views

7,571

Mentions per month

Jan 2019 – Aug 2025

Where it's discussed

  • News318 articles
  • X / Twitter96 posts
  • Facebook94 posts
  • Blogs35 articles
  • Reddit9 posts
  • YouTube3 videos

AI synopsis

What people are saying

Many discussions highlight the effectiveness of the weight management program, with users noting that '46% put T2D into remission' and emphasizing the importance of weight loss as a treatment option. Phrases such as 'impressive clinical trial' and 'weight loss should be the first line of treatment' further underscore the enthusiasm and urgency in adopting the findings. This choice of wording, along with a generally optimistic tone, suggests participants view the study as a crucial step in diabetes management.

AgreementModerate agreement

A majority of discussions reflect a positive reception towards the findings of the publication, indicating a general agreement with its conclusions.

InterestHigh interest

Many participants express a high level of interest, referencing various aspects of the study and its implications for diabetes management.

EngagementModerate engagement

While some discussions are informative, not all participants engage deeply; references to the study exist without extensive personal reflection.

ImpactHigh impact

The conversations indicate a belief that the study has significant implications for diabetes treatment and management.

Abstract in brief

  • Type 2 diabetes is a lifelong chronic condition, and this study, called DiRECT, explored whether a weight management program in primary care could help achieve remission from diabetes.
  • Participants aged 20-65 with type 2 diabetes were either given an intensive weight management program or received standard care, with outcomes focused on significant weight loss and diabetes remission measured after 12 months.
  • Results showed that 24% of those in the weight management group lost 15 kg or more, while no one in the standard care group achieved this level of weight loss.

Top posts

Most liked on X and Bluesky
Jaime A. Gómez Rosero
@JagomezR_MD · X

Lean ME, Leslie WS, Barnes AC, et al. Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster- randomised trial. Lancet 2018;391:541–551 Lean MEJ, et al Lancet Diabetes Endocrinol 2019;7:344–355

Sep 28, 2022 · 84 likes · 7 shares · 63,542 followers View post →
Mats Jacob H:son Lin
@Medicinmanden · X

Imponerende klinisk forsøg (Lancet, 2018), som viser at halvdelen kan blive fri for type 2-diabetes i almen praksis, hvis man stopper med diabetes- og blodtryksmedicin og i stedet indfører et struktureret, diætbaseret vægttabs-program.

Jul 25, 2023 · 51 likes · 4 shares · 1,304 followers View post →
Nick
@upRootNutrition · X

One of the most successful outpatient dietary weight loss trials in history relied almost exclusively on ultra-processed foods for the vast majority of the observed weight loss. Cope. ¯\_(ツ)_/¯ https://t.co/2E0u4JjYId

Jan 12, 2025 · 23 likes · 4 shares · 9,481 followers View post →
イシヤク | 医師向け薬剤比較アプリ
@IshiyakuApp · X

2型糖尿病が被検者の実験で、 ・糖尿病食で糖尿病が改善したのは4% ・825〜853kcal/日の食事を数カ月続けると86%が糖尿病を治せた と報告されています。糖尿病の方は摂取カロリーの見直しをしてみても良いかもしれませんね。 https://t.co/c3zmqHOB9O

May 14, 2023 · 12 likes · 4 shares · 19,170 followers View post →
Nick
@upRootNutrition · X

Twin Cycles Hypothesis: https://t.co/VX9vm8p1Xh Personal Fat Threshold: https://t.co/gmXATyQojA Counterpoint Study: https://t.co/DEYthgE3B2 Counterbalance Study: https://t.co/Y8pcmBxlXA DiRECT Trial: https://t.co/2E0u4JBzzL DiRECT Two-Year Follow-up: https://t.co/z7TQipbb5F https://t.co/esq1uGUly4

Mar 12, 2022 · 9 likes · 9,481 followers View post →
Nick
@upRootNutrition · X

@FoodFirst_Ty Counterpoint: https://t.co/DEYthgE3B2 Counterbalance: https://t.co/gnKJtWxBhc DiRECT Trial: https://t.co/2E0u4JBzzL https://t.co/z7TQipbb5F Reviews: https://t.co/gmXATyQojA https://t.co/UAaYN5xXTp https://t.co/UfdPBWtHwQ This is pretty much all of Roy Taylor's work.

Nov 23, 2020 · 9 likes · 3 shares · 9,481 followers View post →

All mentions

Mind Muscle Project
@mindmusclepro · X

https://t.co/3mtpJI4nq2

Aug 4, 2025 · 24,240 followers View post →
Shahriar
@SugarKoat · X

1. DIRECT Trial (Diabetes Remission Clinical Trial) First major publication: Title: Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial Journal: The Lancet, 2018 PMID: 29221645 Follow-up 2-year results: PMID:

Jun 23, 2025 · 6,580 followers View post →
Christoffer Baustad Nilsen
@ChristofferBN · X

@Pl4ntbased @TyRBeal This study showed great results for weight loss-shakes. So there's that. https://t.co/vniAoyVAZo

May 7, 2025 · 4 likes · 586 followers View post →
Gamba
@silas_kg · X

primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial. →https://t.co/xbftzamOao #MedEd #HealthTips https://t.co/Tpb5wmDEGd

Apr 25, 2025 · 3,896 followers View post →
青島周一
@syuichiao89 · X

https://t.co/IjD5GFQV8y #JJCLIP https://t.co/OUFrLV2FSd

Apr 13, 2025 · 8,608 followers View post →
Miguel Lara
@MiguelL66777 · X

Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial - The Lancet https://t.co/qwXcUMTwSY

Apr 2, 2025 View post →
AhmadHesam
@AhmadHe88222021 · X

https://t.co/NtZKMC9rDu Volkserkrankung Diabetes - Heilbar oder Unaufhaltsam?

Feb 2, 2025 · 97 followers View post →
Konrad
@Konrad06527208 · X

@AndrzejDunowski @CK_inzynier @blueeyedboy88 @PludowskiLukasz Wystarczy 9 tygodni na KAŻDEJ diecie prowadzącej do spadku wagi o 10-15 procent-Badania Roy Taylor i in. https://t.co/g2VxRiwKSQ

Jan 20, 2025 · 211 followers View post →
.
@R6e7x0CCt · X

RT @upRootNutrition: One of the most successful outpatient dietary weight loss trials in history relied almost exclusively on ultra-process…

Jan 12, 2025 · 4 shares · 60 followers View post →
Aaron Lepeska
@AaronLepeska · X

RT @upRootNutrition: One of the most successful outpatient dietary weight loss trials in history relied almost exclusively on ultra-process…

Jan 12, 2025 · 4 shares · 178 followers View post →
riggers
@deportriggers · X

RT @upRootNutrition: One of the most successful outpatient dietary weight loss trials in history relied almost exclusively on ultra-process…

Jan 12, 2025 · 4 shares · 111 followers View post →
Nick
@upRootNutrition · X

One of the most successful outpatient dietary weight loss trials in history relied almost exclusively on ultra-processed foods for the vast majority of the observed weight loss. Cope. ¯\_(ツ)_/¯ https://t.co/2E0u4JjYId

Jan 12, 2025 · 23 likes · 4 shares · 9,481 followers View post →
Tara Taylor
@coldcoqui · X

RT @igoreckert: @ElieJarrougeMD @MohammedAlo These patients are in peer-reviewed medical papers: https://t.co/svUSPFSES3 Weight loss cause…

Dec 16, 2024 · 1 share · 381 followers View post →
Igor Eckert
@igoreckert · X

@ElieJarrougeMD @MohammedAlo These patients are in peer-reviewed medical papers: https://t.co/svUSPFSES3 Weight loss causes diabetes reversal with a very clear dose-response relationship. The fact that diabetes can be prevented, managed or reversed by weight loss and lifestyle modification does not mean

Dec 16, 2024 · 4 likes · 1 share · 16,781 followers View post →
Pilgrim
@villagerssn · X

@NullifyMAGALies @KinseyKat1 @ryanbeed @RICHLS8 @richykirsh @michellewither6 @Vickie627 @ahrehead @WondersNorbit @Dooooooooooodie @FiendInno @AdorablePodcast @o518o518 @Resistenzanow @abortivus @ArchLuminous @jimaw63 @8BrianVogel4 @2024fighter @hoothathuh @KirchoffSh62598 @TW175663056 @cbeckj @EMNODAERTTONOD @kim_because @MichelleinAZ602 @Badams820 @PaulStetson13 @OzzieMalone1 @WhiteRonin22 @BabeTruth2 @MichaelSteidel @PatricktheB @lastword4me2a @Jcatsgots9 @DOnyali26 @proundpapaof3 @Wanderinglord @SophiaBianchi99 @DocDeezWhat @LGiancano @_DarleneBoyd @IamGhostOfTick1 @4horseshoesbw @VinceGottalotta @HamRadioJoe @GenChaoticGood

Jul 24, 2024 · 1 like · 2,634 followers View post →
kom.com
@komomo_Com · X

https://t.co/Bz5CW3sOwz

Jun 28, 2024 · 472 followers View post →
Nick
@upRootNutrition · X

@RickTheV1 @XDB500 @Veganella_ @environmentonig Whoa, friendly fire. Those diets are based for T2DM remission. https://t.co/2E0u4JkwxL

Apr 7, 2024 · 2 likes · 9,481 followers View post →
Chef Ty, RDN, CNSC
@FoodFirst_Ty · X

@XDB500 @trist_cole Here’s a put up or shut up challenge. Refute this literature on fat threshold as the mechanism for DM2 and supporting trials. https://t.co/jKq7vAPghe https://t.co/pIFoeJHe7n https://t.co/bjcAk4kBYj https://t.co/PSl2sSV3n5 https://t.co/bmMw35YsxN

Mar 2, 2024 · 1 like · 2,134 followers View post →
Biomass Bob
@SentientBlobBob · X

@MacroFour @_advg_ @ScepticalDoctor @HPG_Farmer @lowcarbGP And I am truly curious. https://t.co/X9zKpktjYI Diabetes remission was achieved in 68 (46%) participants in the intervention group and six (4%) participants in the control group

Feb 19, 2024 · 785 followers View post →
Ofure Asotie.
@Fuure_sama · X

RT @the_beardedsina: @GBlewusi Yes, there are a ton of them 1. https://t.co/v3k8fxef9M 2. https://t.co/ynOVKjvNro 3. https://t.co/WD6ABy4M…

Jan 29, 2024 · 1 share · 2,688 followers View post →
The_Bearded_Dr_Sina
@the_beardedsina · X

@GBlewusi Yes, there are a ton of them 1. https://t.co/v3k8fxef9M 2. https://t.co/ynOVKjvNro 3. https://t.co/WD6ABy4M20 4. https://t.co/LVDVnPmMyp 5. https://t.co/bln02WynZj

Jan 29, 2024 · 4 likes · 1 share · 223,447 followers View post →
Chef Ty, RDN, CNSC
@FoodFirst_Ty · X

@bakrantz Also I question your claim regarding simply cutting carbs. Weight loss in general (no matter if you lower carbs or fats) improves all pertinent markers for diabetes. https://t.co/bjcAk4kBYj https://t.co/PSl2sSV3n5 https://t.co/bmMw35YsxN https://t.co/8mmOiepiJS

Jan 26, 2024 · 2,134 followers View post →
Spoonz131
@Spoonz1311 · X

RT @FoodFirst_Ty: @adambailes007 @zachinpractice @RetrogradeAgain Much more likely related to chronic energy overconsumption and adipose th…

Jan 24, 2024 · 1 share · 96 followers View post →
Chef Ty, RDN, CNSC
@FoodFirst_Ty · X

@adambailes007 @zachinpractice @RetrogradeAgain Much more likely related to chronic energy overconsumption and adipose threshold. https://t.co/pIFoeJHe7n https://t.co/bjcAk4kBYj https://t.co/PSl2sSV3n5 https://t.co/bmMw35YsxN https://t.co/8mmOiepiJS https://t.co/jKq7vAPghe

Jan 24, 2024 · 2 likes · 1 share · 2,134 followers View post →
Yash Adroja
@yash_adroja · X

Professor Roy Taylor’s work is truly remarkable. Recently I got through reading his clinical trials and recommend them to anyone interested in diabetes. Start Here: https://t.co/p1hr0TpaN6 https://t.co/QNYLNdvWjr https://t.co/knlFG8TIbV

Jan 14, 2024 · 1 like · 630 followers View post →
sashjoon
@sashizam · X

Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial https://t.co/6ow0N5C71q

Jan 13, 2024 · 11 followers View post →
Robin Larsson
@RobinLarssonRPT · X

@ScepticalDoctor E.g: - https://t.co/FTJBYA27JM - https://t.co/RRxfbW94ab - DOI: 10.1016/S0140-6736(17)33102-1 - DOI: 10.1016/S2213-8587(19)30068-3 - DOI: 10.1111/dme.12116

Dec 31, 2023 · 78 followers View post →
Greta Compton Dip DH RCSEd aka Gretsky
@Gretsky_Compton · X

Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial - The Lancet https://t.co/jRYFUd6ZfE

Nov 12, 2023 · 901 followers View post →
Dr. Pascoal Figueiredo
@francis61862897 · X

Referências: 1. Lean, M. E., Leslie, W. S., Barnes, A. C., Brosnahan, N., Thom, G., McCombie, L., ... & Taylor, R. (2017). Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial. The Lancet, 391(10120), 541-551.

Sep 2, 2023 · 5 followers View post →
Manotazo
@Manitazo · X

RT @Medicinmanden: Imponerende klinisk forsøg (Lancet, 2018), som viser at halvdelen kan blive fri for type 2-diabetes i almen praksis, hvi…

Jul 27, 2023 · 4 shares · 784 followers View post →
OnTheFence-Watching
@_Naezu_ · X

RT @Medicinmanden: Imponerende klinisk forsøg (Lancet, 2018), som viser at halvdelen kan blive fri for type 2-diabetes i almen praksis, hvi…

Jul 27, 2023 · 4 shares · 293 followers View post →
Mine Børns Verden
@MBVerden · X

RT @Medicinmanden: Imponerende klinisk forsøg (Lancet, 2018), som viser at halvdelen kan blive fri for type 2-diabetes i almen praksis, hvi…

Jul 25, 2023 · 4 shares · 35 followers View post →
Mats Jacob H:son Lin
@Medicinmanden · X

Imponerende klinisk forsøg (Lancet, 2018), som viser at halvdelen kan blive fri for type 2-diabetes i almen praksis, hvis man stopper med diabetes- og blodtryksmedicin og i stedet indfører et struktureret, diætbaseret vægttabs-program.

Jul 25, 2023 · 51 likes · 4 shares · 1,304 followers View post →
quakadood996
@quakadood996 · X

In fact, his RCT put patients on a severely calorie-restricted diet intervention, containing 59% carbohydrates (a lot of carbohydrates), which resulted in 46% of intervention group patients being put on type 2 diabetes remission. https://t.co/CLVcpY5bC7

Jun 27, 2023 · 7 likes · 342 followers View post →
Maria Emmerich
@MariaEmmerich · X

@SeamusMulsow @KenDBerryMD https://t.co/yp0FkdRc22 https://t.co/ICWdzLabVP https://t.co/tG9ElRGX3M https://t.co/OSb12kDRHl https://t.co/oI4xPGnwpI

May 31, 2023 · 34,117 followers View post →
青島周一
@syuichiao89 · X

まあ、この論文を読んだときには、わりと衝撃があった。 Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised tri… https://t.co/IjD5GFQV8y

May 20, 2023 · 5 likes · 8,608 followers View post →
小川糖尿病内科クリニック
@yoshi28183635 · X

RT @IshiyakuApp: 2型糖尿病が被検者の実験で、 ・糖尿病食で糖尿病が改善したのは4% ・825〜853kcal/日の食事を数カ月続けると86%が糖尿病を治せた と報告されています。糖尿病の方は摂取カロリーの見直しをしてみても良いかもしれませんね。 https:/…

May 15, 2023 · 4 shares · 1,177 followers View post →
茶々ママ☔️
@MR1BE7ReSV2Zd3Z · X

RT @IshiyakuApp: 2型糖尿病が被検者の実験で、 ・糖尿病食で糖尿病が改善したのは4% ・825〜853kcal/日の食事を数カ月続けると86%が糖尿病を治せた と報告されています。糖尿病の方は摂取カロリーの見直しをしてみても良いかもしれませんね。 https:/…

May 14, 2023 · 4 shares · 1,098 followers View post →
イシヤク | 医師向け薬剤比較アプリ
@IshiyakuApp · X

2型糖尿病が被検者の実験で、 ・糖尿病食で糖尿病が改善したのは4% ・825〜853kcal/日の食事を数カ月続けると86%が糖尿病を治せた と報告されています。糖尿病の方は摂取カロリーの見直しをしてみても良いかもしれませんね。 https://t.co/c3zmqHOB9O

May 14, 2023 · 12 likes · 4 shares · 19,170 followers View post →
exfatloss
@exfatloss · X

@JohnnyScott234 @DoctorTro This https://t.co/DJxHXYnm4K? 46% put T2D into remission, yet only 24% lost 15kg or more. I don't see any mentioning of liver fat stores. Again, I don't see evidence that fat loss CAUSED diabetes remission.

May 5, 2023 · 6,576 followers View post →
Stephan J. Guyenet
@sguyenet · X

@jonbischke @TyRBeal @mackinprof @vanvlietphd @fleroy1974 @mario_kratz @davidludwigmd There are many supporting lines of evidence but here are two key papers. https://t.co/MdRIBsvTVN https://t.co/xjZTdRX21w

Apr 18, 2023 · 5 likes · 48,842 followers View post →
Jhon
@Jhonjagudelo · X

@endocrinorosero Doctor, el Estudio Direct, publicado por The Lancet en 2018, no cuenta? "Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial https://t.co/4EjMoLDT3G

Apr 6, 2023 · 1 like · 1,861 followers View post →
cilentano.it
@cilentano_it · X

Gestione del peso guidata dall'assistenza primaria per la remissione del diabete ditipo 2 (DiRECT) Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial. FONTE: https://pubmed.ncbi.nlm.nih. https://t.co/1abh8n2ZiD https://t.co/g4Rg6d6LVW

Apr 5, 2023 · 70 followers View post →
Anna Bonet Esteve
@annabonet · X

Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial https://t.co/64HRtnEbY0

Feb 28, 2023 · 912 followers View post →
ueli steinemann
@DurischLaax · X

Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial https://t.co/eWLKSkjd7w

Jan 30, 2023 · 1 followers View post →
Alex Leaf
@AlexJLeaf · X

Moving on, the final study I want to mention is Roy Taylor’s most recent: the year-long DiRECT study. This was the largest intervention by far, involving nearly 300 adults with T2DM from 49 separate primary care practices. https://t.co/D622WxRPSx

Jan 22, 2023 · 9 likes · 3,941 followers View post →
Sharona Azriel
@SharonaAzriel · X

RT @CristobMorales: https://t.co/NvoZI0y7de Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cl…

Dec 17, 2022 · 1 share · 1,399 followers View post →
Cristobal Morales
@CristobMorales · X

https://t.co/NvoZI0y7de Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial https://t.co/STl72xk1X8

Dec 17, 2022 · 2 likes · 1 share · 17,032 followers View post →
Gabriel Gato Cabañas M.
@CandigatoMID · X

Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial https://t.co/x5rwEHhuMQ

Dec 15, 2022 · 402 followers View post →
منار
@mnr_mnr_517 · X

رابط الدراسة للاطلاع : https://t.co/9gC17SYn1K

Dec 11, 2022 · 160 followers View post →
Lord Arckadius™
@LordArckadius · X

Why are you lying, Ragen Chastain? https://t.co/5Gjdumu6rv https://t.co/2JUTPXyf5X

Oct 19, 2022 · 157 followers View post →
Carlos Marin L.
@Marinmd24 · X

En el grupo de intervención: ✅HBA1C ⬇️0.9% ✅ Antidiabéticos prescritos ⬇️ 0.8 ✅No hubo reducción en anti hipertensivos prescritos ✅ Mejoría en cuestionarios de calidad de vida https://t.co/wNacCzcQW3 https://t.co/CEHmWFt1le

Oct 8, 2022 · 4 likes · 801 followers View post →
Roberto Gutiérrez
@DrRobertoGuti · X

RT @medinternajg: Lean ME, Leslie WS, Barnes AC, et al. Primary care-led weight management for remission of type 2 diabetes (DiRECT): an op…

Sep 29, 2022 · 7 shares · 782 followers View post →
KZ
@k_ellyza · X

RT @medinternajg: Lean ME, Leslie WS, Barnes AC, et al. Primary care-led weight management for remission of type 2 diabetes (DiRECT): an op…

Sep 29, 2022 · 7 shares · 444 followers View post →
Paola
@Paola_Marquez_ · X

RT @medinternajg: Lean ME, Leslie WS, Barnes AC, et al. Primary care-led weight management for remission of type 2 diabetes (DiRECT): an op…

Sep 28, 2022 · 7 shares · 169 followers View post →
DIANITA
@DIANA99155635 · X

RT @medinternajg: Lean ME, Leslie WS, Barnes AC, et al. Primary care-led weight management for remission of type 2 diabetes (DiRECT): an op…

Sep 28, 2022 · 7 shares · 92 followers View post →
Jaime A. Gómez Rosero
@JagomezR_MD · X

Lean ME, Leslie WS, Barnes AC, et al. Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster- randomised trial. Lancet 2018;391:541–551 Lean MEJ, et al Lancet Diabetes Endocrinol 2019;7:344–355

Sep 28, 2022 · 84 likes · 7 shares · 63,542 followers View post →
Nemencio A. Nicodemus Jr
@DokNemie · X

@docdomeng Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial https://t.co/2bYh1ub5Km

Sep 22, 2022 · 2,317 followers View post →
Nir Tsabar
@NirTsabar · X

@GrMeir @TomerAvital1 שאלה מצויינת. למעשה התרופות גורמות לרעב-לפחמימות ומאלצות את המטופלים לצרוך עוד פחמימות, כך שנוצר מעגל קסמים מזיק. חלק מהרופאים מבינים זאת ומשתמשים בשיטת DiRECT - הפחתת תרופות יחד עם שינוי אורח חיים https://t.co/rW3brVXxP7 הרופאים האלו אינם מוזמנים להרצות בכנסים ובקורסים שבחסות...

Jul 12, 2022 · 1 like · 229 followers View post →
RT
@bimal2378 · X

Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial - The Lancet https://t.co/JP4NwcVvwj

Jun 25, 2022 · 37 followers View post →
Nick
@upRootNutrition · X

Twin Cycles Hypothesis: https://t.co/VX9vm8p1Xh Personal Fat Threshold: https://t.co/gmXATyQojA Counterpoint Study: https://t.co/DEYthgE3B2 Counterbalance Study: https://t.co/Y8pcmBxlXA DiRECT Trial: https://t.co/2E0u4JBzzL DiRECT Two-Year Follow-up: https://t.co/z7TQipbb5F https://t.co/esq1uGUly4

Mar 12, 2022 · 9 likes · 9,481 followers View post →
Brian
@themerl12 · X

@REV_Insulin_Res @GoateeWoodson @houston_ron The one thing that seems to be consistent is weight loss, so it's a fair assumption IMO. And it's consistent with what both you seem to have experienced. https://t.co/aBMFrZ2Rjm https://t.co/cEwqC7HP1d https://t.co/SHZdoX6SUc

Mar 5, 2022 · 67 followers View post →
د . محمد الشهري
@drshahri · X

RT @drshahri:

Aug 3, 2021 · 5 shares · 30,027 followers View post →
Nasser Abdullah
@Nasser737Nasser · X

RT @drshahri:

Aug 3, 2021 · 5 shares · 271 followers View post →
علي بن ابراهيم
@ali05505a · X

RT @drshahri:

Aug 3, 2021 · 5 shares · 624 followers View post →
أم عمر
@WGJ52Ppb2ytO8Zc · X

RT @drshahri:

Aug 3, 2021 · 5 shares · 758 followers View post →
د.علي المالكي
@almalki729 · X

RT @drshahri:

Aug 3, 2021 · 5 shares · 330 followers View post →
د . محمد الشهري
@drshahri · X

Aug 3, 2021 · 4 likes · 5 shares · 30,027 followers View post →
Mikael Fogelholm
@MikaelFogelholm · X

@pannilak @flowtiina @Dr_ML_md En löytänyt kuin 1 v dataa Virrasta. Ihan kiinnostava, tietenkin. Joka tapauksessa ongelmia ovat satunnaistamisen puuttuminen ja valikoituminen jo alussa (kenellä on rahaa ja motivaatiota) ja vielä enemmän seurannassa. Parempi asetelma -> ks. DiRECT https://t.co/1Vzps0l7UM

Apr 3, 2021 · 1 like · 5,612 followers View post →
NjagiE
@EllenNjagi · X

Weight loss can put Type 2 diabetes into remission for at least two years – the latest findings from DiRECT https://t.co/e48GD9JLve

Feb 5, 2021 · 19 followers View post →
Bhopender Thakur
@TheBhupiThakur · X

RT @The_Nutrivore: @FoodFirst_Ty Counterpoint: https://t.co/DEYthgE3B2 Counterbalance: https://t.co/gnKJtWxBhc DiRECT Trial: https://t.co/2…

Dec 7, 2020 · 3 shares · 1,369 followers View post →
Bhopender Thakur
@TheBhupiThakur · X

RT @The_Nutrivore: @FoodFirst_Ty Counterpoint: https://t.co/DEYthgE3B2 Counterbalance: https://t.co/gnKJtWxBhc DiRECT Trial: https://t.co/2…

Nov 23, 2020 · 3 shares · 1,369 followers View post →
Nick
@upRootNutrition · X

@FoodFirst_Ty Counterpoint: https://t.co/DEYthgE3B2 Counterbalance: https://t.co/gnKJtWxBhc DiRECT Trial: https://t.co/2E0u4JBzzL https://t.co/z7TQipbb5F Reviews: https://t.co/gmXATyQojA https://t.co/UAaYN5xXTp https://t.co/UfdPBWtHwQ This is pretty much all of Roy Taylor's work.

Nov 23, 2020 · 9 likes · 3 shares · 9,481 followers View post →
William Acosta
@wdanielmh · X

RT @PABLOLUNA: @DrGiovanniD Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised…

Sep 25, 2020 · 1 share · 393 followers View post →
Pablo Luna Rodriguez
@PABLOLUNA · X

@DrGiovanniD Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial https://t.co/Xz5kwaWCh5

Sep 25, 2020 · 1 like · 1 share · 228 followers View post →
F.kei
@Fkei15725719 · X

@ojyo_k Primary care-led weight management for remission of type 2 diabetesこの論文と王城聖帝の運動療法には心から感謝しています、66歳でデブでもないので、時間がかかり、何度も挫折しそうになりましたが、良かった。

Sep 6, 2020 · 4 likes · 66 followers View post →
Eve Beavers
@espacetimeCO · X

Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial - The Lancet https://t.co/rwf3RZauNO

Jul 16, 2020 · 901 followers View post →
Juan Bravo Acuña
@getaped · X

Pero... ¿no habíamos quedado en que la #diabetes se curaba perdiendo peso? Primary Care-Led Weight Management for Remission of Type 2 Diabetes (DiRECT): An Open-Label, Cluster-Randomised Trial - PubMed https://t.co/xbUliWWDfy https://t.co/dsFlCxTJme

Jul 2, 2020 · 1 like · 1,878 followers View post →
Lic. Fernando Luna
@NutricionLP · X

RT @KevinH_PhD: @DrSarahHallberg @rebelhealth1 @bcorkey @ketonemics Evidence from the DiRECT study suggests that low carb diets are not the…

Jun 16, 2020 · 2 shares · 354 followers View post →
daboochmeister
@daboochmeister · X

@BioLayne And before he pulls the “but you’re metabolically healthy” card - in the DiRECT trial, people put their T2DM in remission with 3 months of 125gms carb/day, and kept it in remission with a maintenance diet of ~300gms carb/day. Nuance and context. https://t.co/9zy4QVoDoT

Jun 16, 2020 · 16 followers View post →
Peter Crawford
@ketonemics · X

RT @KevinH_PhD: @DrSarahHallberg @rebelhealth1 @bcorkey @ketonemics Evidence from the DiRECT study suggests that low carb diets are not the…

Jun 15, 2020 · 2 shares · 1,690 followers View post →
Kevin Hall
@KevinH_PhD · X

@DrSarahHallberg @rebelhealth1 @bcorkey @ketonemics Evidence from the DiRECT study suggests that low carb diets are not the *only way* for people with type 2 diabetes to achieve these goals. https://t.co/y1BbzK4zi6

Jun 15, 2020 · 2 likes · 2 shares · 37,724 followers View post →
Andrew Ryan
@OhhiyoGarmen · X

@MacroFour @EAllen0417 @ScottVMeyers @bigfatsurprise I don't know why you're going off on NAFLD patho

Mar 6, 2020 · 27 followers View post →
galactic baseballer
@reignitedx · X

RT @ferchobarb: Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial. htt…

Apr 24, 2019 · 1 share · 242 followers View post →
Ozymandias
@ferchobarb · X

Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial. https://t.co/fMyHKygsjr https://t.co/8UK7234xhP

Apr 24, 2019 · 4 likes · 1 share · 7,162 followers View post →
Agustin
@agustiin_alanis · X

RT @IntJObesity: Meet one of the members of the @IntJObesity editorial board, Professor @MEJLean. His recent papers on type 2 diabetes rem…

Apr 22, 2019 · 7 shares · 453 followers View post →
British Journal of Sports Medicine (BJSM)
@BJSM_BMJ · X

RT @IntJObesity: Meet one of the members of the @IntJObesity editorial board, Professor @MEJLean. His recent papers on type 2 diabetes rem…

Apr 22, 2019 · 7 shares · 109,680 followers View post →
Robert Oh, MD, MPH
@RobertOhMD · X

Type 2 Diabetes - maybe we CAN put it into remission! (through #lifestyle) not medications. Primary care-led weight management for remission of type 2 #diabetes (DiRECT): an open-label, cluster-randomised trial https://t.co/G7nzWUyyKw

Mar 26, 2019 · 1,759 followers View post →
شهاب السيد
@px__tx2 · X

Further Reading Lean, M.E., Leslie, W.S., Barnes, A.C., Brosnahan, N., Thom, G., McCombie, L., Peters, C., Zhyzhneuskaya, S., Al-Mrabeh, A., Hollingsworth, K.G. and Rodrigues, A.M., 2017. Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label,

Mar 2, 2019 · 829 followers View post →
Morven Lean
@Mleanmachine · X

RT @IntJObesity: Meet one of the members of the @IntJObesity editorial board, Professor @MEJLean. His recent papers on type 2 diabetes rem…

Feb 22, 2019 · 7 shares · 121 followers View post →
Ted Kyle
@ConscienHealth · X

@ZaherToumi I don't see any obvious issues with the design of this study (FWLIW

Feb 1, 2019 · 11,301 followers View post →
Julian Sweetman
@sweetman_julian · X

Seems a drastic regimen for 3 - 5 months but hard to argue with T2DM remission of almost 50%. https://t.co/TtfvpUimLC #diabetes #diet

Jan 27, 2019 · 1 like · 12 followers View post →
Thrill Science ✡️ עם ישראל חי
@ThrillScience · X

Primary care-led weight management for remission of type 2 diabetes. https://t.co/rNtOn5ISAI 86% of people who lost 33 lbs or more had complete remission. Shouldn't weight loss be the _first_ line of treatment for obese people with Type 2 diabetes?

Jan 21, 2019 · 38,271 followers View post →
Matt Alvarez
@MattRAlvarez · X

RT @IntJObesity: Meet one of the members of the @IntJObesity editorial board, Professor @MEJLean. His recent papers on type 2 diabetes rem…

Jan 12, 2019 · 7 shares · 401 followers View post →
Critical Care Department @UHSussex West
@UHSussexWest_CC · X

@WSHT_ICU JC 11th Jan - Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial https://t.co/kA1Zrx3Tve

Jan 6, 2019 · 716 followers View post →
Christopher Sylvain
@ChrisSylvain · X

Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial - The Lancet https://t.co/OZyyQVYgQ6

Jan 2, 2019 · 590 followers View post →