Imagine there was a #diet that could help manage obesity, bulk up your #brain's #memory center and potentially fight off #AlzheimersDisease all at once! Learn more about the positive #neuro benefits of #fasting and #ketosis by tuning into #NeuroscIQ https://t.co/QgyuLgWvhE
Intermittent Fasting Protects against Alzheimer's Disease Possible through Restoring Aquaporin-4 Polarity.
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Nov 2019 – Oct 2022Where it's discussed
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News10 articles
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X / Twitter9 posts
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Facebook5 posts
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Blogs2 articles
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AI synopsis
What people are saying
The overall tone indicates strong support and curiosity, exemplified by remarks like 'Intermittent fasting is the greatest discovery' and references to mechanisms such as aquaporin-4 and the glymphatic system. Words like 'transformed' and 'game changer' reflect excitement, while mentions of personal benefits suggest active engagement with the research's potential impact.
Most discussions express strong support or positive attitudes towards the article's findings, with some claiming intermittent fasting as a transformative discovery.
Posts show high interest, with several individuals sharing personal experiences, potential health benefits, and enthusiasm about the research.
The discussions reflect some depth, referencing mechanisms like the glymphatic system and aquaporin-4 function, indicating thoughtful engagement with the scientific content.
Participants believe the findings could have significant implications for health, especially in preventing or managing Alzheimer's disease and related neurodegenerative conditions.
Abstract in brief
- Intermittent fasting (IF) may help protect against Alzheimer's disease (AD) by restoring the proper distribution (polarity) of aquaporin-4 (AQP4) in the brain, which is important for clearing amyloid beta (A) plaques.
- The study suggests that IF increases levels of hydroxybutyrate, which inhibits histone deacetylase 3 (HDAC3) and affects the ratio of AQP4 isoforms (M1 and M23), leading to improved AQP4 function and reduced amyloid accumulation.
- The findings also indicate that microRNA130a (miR130a) plays a key role in regulating AQP4 isoforms and HDAC3, with IF and hydroxybutyrate boosting miR130a levels to support brain health and cognitive function in AD models.
Top posts
Most liked on X and BlueskyWow. At least in mice: Intermittent Fasting Protects against Alzheimer's Disease Possible through Restoring Aquaporin-4 Polarity. - PubMed - NCBI https://t.co/8Av0nWp2Wk
#Jejum intermitente protege contra a doença de #Alzheimer. https://t.co/HrotFmcEme
Proposed one mechanism of benefit of #IntermittentFasting in #Alzheimers #alzheimersdisease due to improved Aquaporin-4 function part of #glymphatic system https://t.co/lbtgkuuXVi
RT @pdiamandisii: Imagine there was a #diet that could help manage obesity, bulk up your #brain's #memory center and potentially fight off…
RT @pdiamandisii: Imagine there was a #diet that could help manage obesity, bulk up your #brain's #memory center and potentially fight off…
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Intermittent Fasting and Brain Health: Protecting Against Alzheimer's Disease
Explore how intermittent fasting may protect against Alzheimer's by restoring aquaporin-4 distribution, enhancing amyloid clearance, and increasing hydroxybutyrate levels, supporting cognitive health.
#Jejum intermitente protege contra a doença de #Alzheimer. https://t.co/HrotFmcEme
RT @dr_kevinlee: Proposed one mechanism of benefit of #IntermittentFasting in #Alzheimers #alzheimersdisease due to improved Aquaporin-4 fu…
Proposed one mechanism of benefit of #IntermittentFasting in #Alzheimers #alzheimersdisease due to improved Aquaporin-4 function part of #glymphatic system https://t.co/lbtgkuuXVi
Wow. At least in mice: Intermittent Fasting Protects against Alzheimer's Disease Possible through Restoring Aquaporin-4 Polarity. - PubMed - NCBI https://t.co/8Av0nWp2Wk
@tdmckee @GarmireGroup I'll put it this way. Intermittent fast is the single greatest (re)discovery I made in my life. I've been doing it for 5 years this new year and it transformed my body, mind and spirit. No APP needed. Find out more https://t.co/QgyuLgWvhE
RT @pdiamandisii: Imagine there was a #diet that could help manage obesity, bulk up your #brain's #memory center and potentially fight off…
RT @pdiamandisii: Imagine there was a #diet that could help manage obesity, bulk up your #brain's #memory center and potentially fight off…
RT @pdiamandisii: Imagine there was a #diet that could help manage obesity, bulk up your #brain's #memory center and potentially fight off…
Imagine there was a #diet that could help manage obesity, bulk up your #brain's #memory center and potentially fight off #AlzheimersDisease all at once! Learn more about the positive #neuro benefits of #fasting and #ketosis by tuning into #NeuroscIQ https://t.co/QgyuLgWvhE
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