BMC Biol December 2017 PMID 29262826

Investigating the physiology of viable but non-culturable bacteria by microfluidics and time-lapse microscopy.

Rosemary A Bamford, Ashley Smith, Jeremy Metz, Georgina Glover, Richard W Titball, Stefano Pagliara

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111

Peak: 3 in Mar 2019

across 3 sources since Mar 2019

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19,422

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Mar 2019 – Dec 2019

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News106 articles
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AI synopsis

What people are saying

Discussions highlight the innovative use of microfluidics and time-lapse microscopy, with posts describing the study’s potential to change understanding of bacterial survival mechanisms. Words like 'significant,' 'innovative,' and 'potential' reflect enthusiasm and belief in the research's importance, while questions about methodology show curiosity and engagement.

AgreementModerate agreement

Most discussions acknowledge the significance of the research, with some emphasizing its innovative approach and potential implications.

InterestHigh interest

Discussion members demonstrate high curiosity about the techniques used and the findings related to bacterial states.

EngagementModerate engagement

Participants mainly share summaries and express curiosity, indicating a moderate but genuine level of engagement.

ImpactModerate impact

There is a consensus that the study could influence future research in microbiology and bacterial resilience.

Abstract in brief

This study introduces a new method combining microfluidics, timelapse microscopy, and fluorescent reporter strains to closely observe individual bacterial cells, especially focusing on the VBNC state that is hard to detect with traditional methods.
The researchers found that VBNC cells are not dead but look similar to persister cells and share phenotypic features, suggesting a possible connection between these two bacterial subpopulations, particularly in Escherichia coli.
Before antibiotic treatment, both persister and VBNC cells can be differentiated from regular cells by their lower fluorescence levels, providing insights into their unique behaviors and potential roles in bacterial resilience.]

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All mentions

Bacterial Resistance Mechanisms and Microfluidic Insights

This video explains bacterial infections, antibiotic treatments, and resistance mechanisms, including altered membrane properties reducing antibiotic uptake. It discusses recent research using microfluidics and…

stefano pagliara · Dec 27, 2019 633 views

Microfluidics and Bacterial Resistance Insights for Antibiotic Development

In this BBC One Spotlight, I explain how microfluidic devices are used to investigate bacterial resistance mechanisms, aiding in the development of improved antibiotic therapies. The approach offers detailed observation…

stefano pagliara · Dec 27, 2019 476 views

Xabier Vázquez-Campos

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RT @BMCBiology: In case you missed it: Investigating the physiology of viable but non-culturable bacteria by microfluidics and time-lapse m…

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BMC Biology

@BMCBiology · X

In case you missed it: Investigating the physiology of viable but non-culturable bacteria by microfluidics and time-lapse microscopy https://t.co/8MbFtugkGI

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