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Participants show high enthusiasm for the research, citing its innovative approach to modifying IgG sialylation to reduce inflammation, and emphasizing its potential as a transformative therapy. Words like 'promising' and 'support' reflect both excitement and recognition of the study’s significance.
Most discussions express strong support and enthusiasm for the study's findings, highlighting its promise in treating autoimmune diseases.
The topics of antibody engineering and autoimmune treatment generate high interest among participants, as seen in mentions of impact and scientific support.
Posts reference specific methods like sialylation and glycoengineering, and discuss implications, demonstrating deep engagement.
The discussions highlight the potential for significant advances in autoimmune therapy, with mentions of awards and scientific support underscoring high impact.
Congratulations to Robert M. Anthony, PhD, for receiving the 2019 Martin Prize for Fundamental Research for his work, "Engineered Sialylation of Pathogenic Antibodies In Vivo Attenuates Autoimmune Disease"! #MassGeneral #MGRI #SAC2019 @MassGeneralNews https://t.co/6bb5E6BRls
Engineered Sialylation of Pathogenic Antibodies In Vivo Attenuates Autoimmune Disease 2017 病気を起こすタイプの抗体に人工的にシアル酸を付加したら自己免疫疾患を抑制 https://t.co/FwmuZsMUSW IgGの糖鎖に、活性化した血小板の顆粒からのガラクトースとシアル酸を糖転写酵素で付け、抗炎症化 https://t.co/KqIPc9JMPS
@__ice9 @assur153 @NG20194 @abledoc @jasonsknight @farid__jalali I don't know if fucosylation of IgG can be modified in tissue or serum, but sialylation can be modified. Engineered Sialylation of Pathogenic Antibodies In Vivo Attenuates Autoimmune Disease 2018 https://t.co/COMCzZLh6t
RT @zzz_as_zzz: Engineered Sialylation of Pathogenic Antibodies In Vivo Attenuates Autoimmune Disease 2017 病気を起こすタイプの抗体に人工的にシアル酸を付加したら自己免疫疾…
RT @zzz_as_zzz: @__ice9 @assur153 @NG20194 @abledoc @jasonsknight @farid__jalali I don't know if fucosylation of IgG can be modified in tis…
The authors of "Engineered Sialylation of Pathogenic Antibodies In…" (https://t.co/3w9WleghjF) included RRIDs in their paper! We appreciate the author's support of reproducibility. #RRID #STMpublishing
Glycan glycosyltransferases are used to modify IgG antibodies, transforming them into anti-inflammatory agents. This approach reduces autoimmune inflammation by targeted sialylation, offering promising therapeutic…
Exploring how engineered sialylation of IgG antibodies can suppress inflammation and offer targeted autoimmune disease therapy.
Glycan glycosyltransferases modify antibodies to reduce inflammation. The study shows engineered enzymes alter IgG glycosylation, decreasing autoimmune issues in vivo by targeting inflammatory sites, offering promising…
Glycan glycosyltransferases glycosylation sialylation galactose autoimmunedisease antiinflammatory sialicacid biology posttranslationalmodification igg invivo inflammation enzymeactivity sialyltransferase B4ST6FC…
Explores how platelets influence in vivo sialylation processes, impacting inflammation and autoimmunity through glycosyltransferase activity, with implications for therapeutic interventions using enzyme engineering to…
This video explains how engineered glycosyltransferases modify IgG antibodies by adding sugars like sialic acid, transforming them into anti-inflammatory agents, and reducing autoimmune inflammation.
In-vivo validation of engineered antibodies demonstrates their potential to reduce autoimmune inflammation by modifying IgG glycosylation, highlighting glycoengineering as a promising therapeutic approach.
RT @zzz_as_zzz: Engineered Sialylation of Pathogenic Antibodies In Vivo Attenuates Autoimmune Disease 2017 病気を起こすタイプの抗体に人工的にシアル酸を付加したら自己免疫疾…
RT @zzz_as_zzz: @__ice9 @assur153 @NG20194 @abledoc @jasonsknight @farid__jalali I don't know if fucosylation of IgG can be modified in tis…
The authors of "Engineered Sialylation of Pathogenic Antibodies In…" (https://t.co/3w9WleghjF) included RRIDs in their paper! We appreciate the author's support of reproducibility. #RRID #STMpublishing
@__ice9 @assur153 @NG20194 @abledoc @jasonsknight @farid__jalali I don't know if fucosylation of IgG can be modified in tissue or serum, but sialylation can be modified. Engineered Sialylation of Pathogenic Antibodies In Vivo Attenuates Autoimmune Disease 2018 https://t.co/COMCzZLh6t
Engineered Sialylation of Pathogenic Antibodies In Vivo Attenuates Autoimmune Disease 2017 病気を起こすタイプの抗体に人工的にシアル酸を付加したら自己免疫疾患を抑制 https://t.co/FwmuZsMUSW IgGの糖鎖に、活性化した血小板の顆粒からのガラクトースとシアル酸を糖転写酵素で付け、抗炎症化 https://t.co/KqIPc9JMPS
Congratulations to Robert M. Anthony, PhD, for receiving the 2019 Martin Prize for Fundamental Research for his work, "Engineered Sialylation of Pathogenic Antibodies In Vivo Attenuates Autoimmune Disease"! #MassGeneral #MGRI #SAC2019 @MassGeneralNews https://t.co/6bb5E6BRls