Cell Host Microbe January 2018 PMID 29276171

Bifidobacteria or Fiber Protects against Diet-Induced Microbiota-Mediated Colonic Mucus Deterioration.

Bjoern O Schroeder, George M H Birchenough, Marcus Ståhlman, Liisa Arike, Malin E V Johansson, Gunnar C Hansson, Fredrik Bäckhed

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Mentions

72
Peak: 1 in Feb 2020
across 5 sources since Feb 2020

Extended reach

17,504
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Feb 2020 – Dec 2023

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AI synopsis

What people are saying

Discussions highlight the importance of bacterial health in preventing mucus deterioration, with references to past studies by prominent research groups and collaborative acknowledgments emphasizing the ongoing relevance of this research. Words like 'excellent' and mentions of 'our work' demonstrate positive reception and a professional interest without extreme urgency.

AgreementStrong agreement

The discussion highly agrees with the publication, citing previous studies and collaborations that support the findings.

InterestModerate interest

There is moderate interest, with some enthusiasm for the research but not overly passionate or urgent.

EngagementModerate engagement

Participants reference other research groups and their own work, indicating a willingness to relate and discuss the broader context.

ImpactModerate impact

While the discussion recognizes the significance of the findings, the tone suggests a professional appreciation rather than a sense of groundbreaking change.

Abstract in brief

  • A Western-style diet (WSD) alters gut microbiota in mice, leading to increased mucus layer breakdown and higher gut barrier permeability.
  • Transplanting microbiota from healthy, chow-fed mice or administering Bifidobacterium longum can restore mucus integrity, suggesting beneficial bacteria are crucial for maintaining the mucus barrier.
  • The fiber inulin also helps prevent mucus penetrability issues, highlighting the protective role of specific bacteria and dietary fibers in gut health, which may have implications for conditions like ulcerative colitis.]

Top posts

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Bjo:rn Schro:der
@bo_schroeder · X

Excellent previous studies by @EricCMartens1, @MDesai_Lab, @LabSonnenburg as well as our own work https://t.co/sKUAfuiIPF) with @GobletCellGuy, @BackhedLab and @MucinBiology found that low-fiber #diet can lead to #gutbacteria-mediated defects of the colonic mucus in mice. 3/17

Dec 14, 2023 · 3 likes · 685 followers View post →

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Bjo:rn Schro:der
@bo_schroeder · X

Excellent previous studies by @EricCMartens1, @MDesai_Lab, @LabSonnenburg as well as our own work https://t.co/sKUAfuiIPF) with @GobletCellGuy, @BackhedLab and @MucinBiology found that low-fiber #diet can lead to #gutbacteria-mediated defects of the colonic mucus in mice. 3/17

Dec 14, 2023 · 3 likes · 685 followers View post →