Eur J Appl Physiol March 2018 PMID 29282529

The development of skeletal muscle hypertrophy through resistance training: the role of muscle damage and muscle protein synthesis.

Felipe Damas, Cleiton A Libardi, Carlos Ugrinowitsch

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Mentions

162
Peak: 8 in Apr 2025
across 9 sources since Dec 2017

Extended reach

273,772
potential audience

Total likes

3,007

Video views

201,407

Mentions per month

Dec 2017 – Dec 2025

Where it's discussed

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AI synopsis

What people are saying

Discussions highlight the shift from traditional views that muscle damage is essential for growth, such as posts stating 'muscle damage doesn't directly correlate with growth.' The tone varies from scientific references to casual debates, showing both interest and engagement in understanding muscle development, which contributes to moderate agreement and impact scores.

AgreementModerate agreement

Most discussions acknowledge that muscle damage is not the primary driver of hypertrophy, aligning with the article's findings.

InterestModerate interest

The social discussions show moderate interest, with mentions of recent research and debates about the role of muscle damage.

EngagementHigh engagement

Many posts reference specific studies, cite research authors, and debate the implications, indicating deep engagement.

ImpactModerate impact

The discussions on muscle damage and hypertrophy could influence training approaches, though are mostly academic rather than practical guidelines.

Abstract in brief

  • The development of muscle hypertrophy from resistance training is complex and not fully understood, but recent research suggests that early increases in muscle size are mainly due to muscle damage and swelling, not actual muscle growth.
  • Muscle protein synthesis (MPS) increases after workouts are initially focused on muscle repair caused by damage, and these increases do not directly lead to hypertrophy until muscle damage decreases over time.
  • Resistance training protocols that cause less muscle damage can still result in similar gains in muscle size and strength, indicating that muscle damage is not a necessary factor for muscle hypertrophy.]

Top posts

Most liked on X and Bluesky
Fred Duncan
@Fred__Duncan · X

The beauty of science and the fragility of knowledge. “RT protocols that do not promote significant muscle damage still induce similar muscle hypertrophy and strength gains compared to conditions that do promote initial muscle damage.“ https://t.co/DgonUTR6wf

Apr 23, 2023 · 3 likes · 11,899 followers View post →
Terapia Manual UE
@terapiamanualUE · X

Aquí el

Dec 21, 2020 · 3 likes · 10,984 followers View post →
Jeremy Ethier
@JeremyEthier95 · X

Muscle damage was once believed to be the holy grail for muscle growth. However, recent studies have revealed a surprising finding: muscle damage doesn't directly correlate with muscle growth. https://t.co/jaVwrJQcRg

Jul 12, 2023 · 3 likes · 3,300 followers View post →
Rafa Lund
@RafaLund · X

Não é o Dano que faz o Músculo Crescer! O desenvolvimento da Hipertrofia do músculo esquelético através do Treinamento de Força: O papel do Dano Muscular e da Síntese Proteica. https://t.co/IN9NTw5eZM

Jul 10, 2023 · 2 likes · 541 followers View post →
Kassiano
@WitaloKassiano · X

@SimonWalkerPhD @SandCResearch Agree. It is a very interesting and intriguing topic. I think that the model proposed by Damas et al., explains reasonably well; although there is still a lot to be understood. https://t.co/9hP2w596S0

Jun 11, 2020 · 2 likes · 1 share · 514 followers View post →
Saburo Hagihara
@saburo_hagihara · X

筋肉痛が、乳酸がたまるためにおこることではなく、筋肉のダメージからくるものと言うのは最近一般的に知られるようになりました。 それとは別に、下の実験では筋肉のダメージが筋肥大に必要ではないという結論を示しています。 ただ、 続く https://t.co/DLIOriipmB

Nov 12, 2021 · 2 likes · 158 followers View post →

All mentions

carlos who beckons
@typecarlosmale · X

@River_ember @Duderichy popular article: https://t.co/beciKryQi5 scientific publication: https://t.co/M3LbCt3vJG.

Feb 19, 2025 · 1 like · 610 followers View post →
Dilara - the kinky Yoga Jedi of Bluesky
@auroradilara.bsky.social · Bluesky

Quelle: pubmed.ncbi.nlm.nih.gov/29282529/

Jan 31, 2025 · 1 share View post →
Fitness.sin.filtros
@Ernessttoo · X

✅️<4 sesiones RT = aumento CSA se debe a la hinchazón [edema] debido al daño muscular. ✅️+10 sesiones RT = modesta hipertrofia muscular. ✅️+18 sesiones RT = verdadera hipertrofia muscular. https://t.co/5CiOQ9nqzy

Sep 13, 2024 · 952 followers View post →
FreeSpeechlmao
@speechlmao · X

@Deezus_Walks Or if you prefer, I can do the linking part: "the development of skeletal muscle hypertrophy through resistance training" this on google, second link should be a PDF https://t.co/Tc5KVPAypB it's also here but it's not as easily accessible

Mar 15, 2024 · 17 followers View post →
IngStrawberry
@ingStrawberry21 · X

@obradam https://t.co/6x5SuC8NCO dobrý den podle téhle studie (pokud ji dobře chápu

Dec 14, 2023 · 18 followers View post →
OJSN
@iamojsn · X

The development of skeletal muscle hypertrophy through resistance training: the role of muscle damage and muscle protein synthesis | Request PDF - https://t.co/tIppQXwQoU

Aug 11, 2023 · 1 like · 15,013 followers View post →
Jeremy Ethier
@JeremyEthier95 · X

Follow for more tips like this! If you’re interested in the exact research studies mentioned above - (1) https://t.co/jaVwrJQcRg (2) https://t.co/557D38N3zI

Jul 13, 2023 · 3,300 followers View post →
Jeremy Ethier
@JeremyEthier95 · X

Muscle damage was once believed to be the holy grail for muscle growth. However, recent studies have revealed a surprising finding: muscle damage doesn't directly correlate with muscle growth. https://t.co/jaVwrJQcRg

Jul 12, 2023 · 3 likes · 3,300 followers View post →
Rafa Lund
@RafaLund · X

Não é o Dano que faz o Músculo Crescer! O desenvolvimento da Hipertrofia do músculo esquelético através do Treinamento de Força: O papel do Dano Muscular e da Síntese Proteica. https://t.co/IN9NTw5eZM

Jul 10, 2023 · 2 likes · 541 followers View post →
Jacob Rauch
@JTRAUCH · X

Links to some of the papers discussed: https://t.co/dzBmbjc67Z https://t.co/fFikEETBPd

May 26, 2023 · 1 like · 408 followers View post →
Poole Fitness
@PooleFitness · X

@orth0girl The development of skeletal muscle hypertrophy through resistance training: the role of muscle damage and muscle protein synthesis 29282529

May 9, 2023 · 105 followers View post →
Poole Fitness
@PooleFitness · X

@ChumaFitness The development of skeletal muscle hypertrophy through resistance training: the role of muscle damage and muscle protein synthesis 29282529 The development of skeletal muscle hypertrophy through resistance training: the role of muscle damage and muscle protein synthesis 29282529

May 6, 2023 · 105 followers View post →
Fred Duncan
@Fred__Duncan · X

The beauty of science and the fragility of knowledge. “RT protocols that do not promote significant muscle damage still induce similar muscle hypertrophy and strength gains compared to conditions that do promote initial muscle damage.“ https://t.co/DgonUTR6wf

Apr 23, 2023 · 3 likes · 11,899 followers View post →
a isadora, powerlifter
@aisadora_ · X

@yvesporto8 Ocorre sim! Só que como você mesmo pontuou, é um trabalho crônico! Trocar os exercícios numa frequência aguda talvez não seja a melhor estratégia pra maximizar a hipertrofia em áreas específicas! Obrigada por acrescentar ao debate!! Vou ler a referência! https://t.co/MsIBXgckGz

Feb 8, 2023 · 1 like · 6,216 followers View post →
toospooky
@toospooky · X

@Adrastos369 @adamcummingsGA I mean, I'm not the one attacking the product nor person. Burden of proof is yours, really. But sure. https://t.co/nW234FnqRv https://t.co/W7SFf5Uhem https://t.co/f4j3zIpc3x https://t.co/dR7AQ8bv4t https://t.co/RVnbeFemfw

May 29, 2022 · 8,513 followers View post →
Leonoesleo⁵² ⁽ᴸᵉⁿ⁾
@len0087 · X

Agreguemosle a esto. El "dolor" se supone que es para que el músculo crezca/ entre en hipertrofia no? Segun estos dos papers, la relación dolor/daño del músculo no parece estar relacionada directamente en hipertrofia

Apr 26, 2022 · 925 followers View post →
Saburo Hagihara
@saburo_hagihara · X

筋肉痛が、乳酸がたまるためにおこることではなく、筋肉のダメージからくるものと言うのは最近一般的に知られるようになりました。 それとは別に、下の実験では筋肉のダメージが筋肥大に必要ではないという結論を示しています。 ただ、 続く https://t.co/DLIOriipmB

Nov 12, 2021 · 2 likes · 158 followers View post →
ゆうすけ@筋トレとオナ禁で人生変えた人
@usk_menshack · X

@sMRXNPLPKZyuWfR https://t.co/jdlTjMRY5S https://t.co/Yy3bjV4c9v どうぞご参考にしていただけたら幸いです。 また、筋組織と筋膜の痛覚閾値を調べた実験では、筋肉痛が生じた筋膜での痛覚閾値が顕著に低下したという報告もあります。

Aug 20, 2021 · 3,571 followers View post →
Terapia Manual UE
@terapiamanualUE · X

Aquí el

Dec 21, 2020 · 3 likes · 10,984 followers View post →
Kassiano
@WitaloKassiano · X

@SimonWalkerPhD @SandCResearch Agree. It is a very interesting and intriguing topic. I think that the model proposed by Damas et al., explains reasonably well; although there is still a lot to be understood. https://t.co/9hP2w596S0

Jun 11, 2020 · 2 likes · 1 share · 514 followers View post →
Lorenzo S.Wayne
@LorenzoSWayne · X

@Jozo_Grgic Thank you Jozo, yeah I remember the study you suggested, but still have some perplexities due to this: https://t.co/wFwgKfEvUi

Jun 9, 2020 · 51 followers View post →
Sebastian Skejø
@sebastianskejoe · X

@rosshm16 @EmilyMatijevich @rwilly2003 @edwardswb @KarlZelik @andyroberts1234 @EveldMaura That seems to be the case for muscles at least; repair is a response to damage, but adaptation (hypertrophy) does not require damage - https://t.co/JERGqLuAHL

Feb 25, 2020 · 146 followers View post →
DimeComoSea
@DimeComoSea · X

Damas F, Libardi CA y Ugrinowitsch C Eur J Appl Physiol. 2018 Mar;118(3):485-500. doi: 10.1007/s00421-017-3792-9

Feb 22, 2020 · 3,154 followers View post →
Siyabonga Masemola
@Siya_M · X

RT @MikeLambert01: Interested in muscle adaptation to resistance training? This review discusses interplay between DOMS and hypertrophy. ht…

Aug 29, 2019 · 10 shares · 493 followers View post →
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@jamessteeleii.bsky.social · Bluesky

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DOI: 10.1007/s00421-017-3792-9 Nosaka & Clarkson (1996): Ağrının şiddeti, kas hasarının ya da büyümenin boyutunu göstermez. Changes in ...

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doi: 10.1007/s00421-017-3792-9. Epub 2017 Dec 27. PMID: 29282529. in MPS post-RT session only contribute to muscle hypertrophy after a ...

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2. Três torres de halteres sextavados emborrachados de 1-10kg; 3. Bancada de haltere de 12 a 30kg; 4. Gaiola multifuncional; 5. ⁠Dois bancos; 6.

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... da sobrecarga e se evite a chegada de um platô. . Referências doi: 10.1007/s00421-017-3792-9 doi: 10.1113/JP272472".

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006 DOI: 10.1007 ... 謝謝你們! ——相關文獻———— DOI:10.1519/JSC.0b013e3181e840f3. DOI:10.1080/17461391.2018.1505957 DOI:10.1007/s00421-017-3792-9.

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謝謝你們! ——相關文獻———— DOI:10.1519/JSC.0b013e3181e840f3. DOI:10.1080/17461391.2018.1505957 DOI:10.1007/s00421-017-3792-9.

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