The overall tone demonstrates strong agreement and interest, with posters frequently sharing links, discussing lactose's metabolic functions, and referencing influential reviews, suggesting the article has highly stimulated curiosity and discourse, especially among educators and students. Phrases like 'helpful and informative read' and 'excellent review' underline positive reception and a desire to incorporate these insights into teaching and research.
AgreementModerate agreement
Most posters express support and appreciation for the article, emphasizing its clarity and contribution to understanding lactate’s functions.
InterestHigh interest
Discussions show high curiosity about lactate's role, with many references to preparing teaching materials and further reading, indicating strong engagement.
EngagementHigh engagement
Posts reflect active involvement, including sharing resources, referencing authors, and contemplating implications, demonstrating deep engagement.
ImpactModerate impact
While many see the article as valuable for educational and research purposes, some comments highlight ongoing debates and the need for updated understanding, indicating moderate to high impact.
Abstract in brief
Lactate has historically been misunderstood as just a waste product caused by low oxygen, but recent research shows it's actually a key fuel and signaling molecule in the body.
The discovery of the cell-to-cell lactate shuttle in the 1980s shifted our understanding, revealing lactate's important role in coordinating overall metabolism and promoting processes like blood vessel growth.
Despite these advances, many aspects of lactate’s functions are still being integrated into clinical and athletic practices, highlighting its potential for various medical applications beyond just being a byproduct of oxygen deficit.]
Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis
Link: https://t.co/bYHHqvn8dL
Video: Professor George Brooks on lactate https://t.co/E9006m0cde https://t.co/7N5OuVykbM
Aug 26, 2019 · 170 likes · 39 shares · 8,594 followersView post →
JL
Jeremy Loenneke
@jploenneke · X
As many of us prepare to lecture on metabolism...here is a nice refresher on lactate
"Glycolysis does not require oxygen and has lactate as its end product, because the equilibrium of the LDH reaction is markedly in favor of lactate."
Link: https://t.co/iTz95vwRPk https://t.co/tAfvjc1VfQ
Aug 19, 2020 · 86 likes · 13 shares · 8,594 followersView post →
JA
Jem Arnold
@jem_arnold · X
Standard schematic representation of constant workload
Jan 21, 2024 · 39 likes · 3 shares · 3,546 followersView post →
JL
Jeremy Loenneke
@jploenneke · X
Trying to wrap your head around "lactate is always the end product of glycolysis"
try these two papers (figure from second link)
https://t.co/GpJX2eAqrB
https://t.co/bYHHqv5xmd https://t.co/GqAV1Il14W
Jan 22, 2019 · 26 likes · 6 shares · 8,594 followersView post →
JL
Jeremy Loenneke
@jploenneke · X
I tweet this paper every single year
i continue to find it to be a very helpful and informative read
https://t.co/Xb15GGxXtj
Aug 24, 2022 · 22 likes · 5 shares · 8,594 followersView post →
JW
Jacob de Wolff
@jfdwolff · X
Here is the link https://t.co/4bufyQMXb2 @EJAP_official
May 19, 2020 · 5 likes · 11,295 followersView post →
This video explains why we should stop referring to lactic acid and instead focus on lactate, a crucial energy and signaling molecule. It covers energy metabolism pathways and recent insights into lactate's vital role…
This video reviews what we know about lactate and its implications for training. Discover how lactate impacts athletic performance and training strategies. Gain valuable insights into optimizing your running, including…
This video explores the biochemistry of exercise-induced metabolic acidosis, highlighting how high-intensity exercise increases proton release from ATP breakdown, and not lactate, which actually prevents acidosis and…
This video clarifies common misconceptions about lactate, explaining how it is not the cause of fatigue or muscle burning. Instead, recent research shows lactate is a key energy source during high-intensity exercise and…
Standard schematic representation of constant workload
Jan 21, 2024 · 39 likes · 3 shares · 3,546 followersView post →
V
Viviana
@VivianAya93 · X
RT @jploenneke: I tweet this paper every single year
i continue to find it to be a very helpful and informative read
https://t.co/Xb15GGx…
Aug 25, 2022 · 5 shares · 133 followersView post →
LD
Lars Donath
@LarsDonath · X
RT @jploenneke: I tweet this paper every single year
i continue to find it to be a very helpful and informative read
https://t.co/Xb15GGx…
Aug 25, 2022 · 5 shares · 832 followersView post →
TK
Tim Kambič
@TimKambic · X
RT @jploenneke: I tweet this paper every single year
i continue to find it to be a very helpful and informative read
https://t.co/Xb15GGx…
Aug 25, 2022 · 5 shares · 232 followersView post →
SC
Sean M. Collins
@SMCollinsPhD · X
RT @jploenneke: I tweet this paper every single year
i continue to find it to be a very helpful and informative read
https://t.co/Xb15GGx…
Aug 24, 2022 · 5 shares · 490 followersView post →
HD
Heath Crawford, DC
@tiger5972 · X
RT @jploenneke: I tweet this paper every single year
i continue to find it to be a very helpful and informative read
https://t.co/Xb15GGx…
Aug 24, 2022 · 5 shares · 263 followersView post →
JL
Jeremy Loenneke
@jploenneke · X
I tweet this paper every single year
i continue to find it to be a very helpful and informative read
https://t.co/Xb15GGxXtj
Aug 24, 2022 · 22 likes · 5 shares · 8,594 followersView post →
PM
Pierre Morel
@NeuroPierre · X
@ElVeider_FDV Cette review est assez complète : https://t.co/f7RTnDUFZk , il y a aussi des batailles de chapelles pour le lien lactate/acidification https://t.co/hxHLtCnrdW
RT @jploenneke: As many of us prepare to lecture on metabolism...here is a nice refresher on lactate
"Glycolysis does not require oxygen a…
Aug 21, 2020 · 13 shares · 61 followersView post →
CP
Caroline Robertson PhD
@C_V_Robertson · X
RT @jploenneke: As many of us prepare to lecture on metabolism...here is a nice refresher on lactate
"Glycolysis does not require oxygen a…
Aug 20, 2020 · 13 shares · 204 followersView post →
MV
Msc Rodrigo Volga
@RodrigoVolga · X
RT @jploenneke: As many of us prepare to lecture on metabolism...here is a nice refresher on lactate
"Glycolysis does not require oxygen a…
Aug 20, 2020 · 13 shares · 126 followersView post →
LW
Lorenzo S.Wayne
@LorenzoSWayne · X
RT @jploenneke: As many of us prepare to lecture on metabolism...here is a nice refresher on lactate
"Glycolysis does not require oxygen a…
Aug 20, 2020 · 13 shares · 51 followersView post →
LM
Laia Monné
@LaiaMonne · X
RT @jploenneke: As many of us prepare to lecture on metabolism...here is a nice refresher on lactate
"Glycolysis does not require oxygen a…
Aug 20, 2020 · 13 shares · 685 followersView post →
YY
Yujiro Yamada
@yujiro3520 · X
RT @jploenneke: As many of us prepare to lecture on metabolism...here is a nice refresher on lactate
"Glycolysis does not require oxygen a…
Aug 19, 2020 · 13 shares · 518 followersView post →
AA
Alex Ojeda-Aravena
@AOjeda_Aravena · X
RT @jploenneke: As many of us prepare to lecture on metabolism...here is a nice refresher on lactate
"Glycolysis does not require oxygen a…
Aug 19, 2020 · 13 shares · 97 followersView post →
NC
Nick J. Siekirk, Ph.D., M.S., CSCS
@nsiekirk · X
RT @jploenneke: As many of us prepare to lecture on metabolism...here is a nice refresher on lactate
"Glycolysis does not require oxygen a…
Aug 19, 2020 · 13 shares · 505 followersView post →
AP
Alex Olmos, PhD
@olmosalex65 · X
RT @jploenneke: As many of us prepare to lecture on metabolism...here is a nice refresher on lactate
"Glycolysis does not require oxygen a…
Aug 19, 2020 · 13 shares · 104 followersView post →
SR
Steve Rafferty
@SteveRaffertySN · X
RT @jploenneke: As many of us prepare to lecture on metabolism...here is a nice refresher on lactate
"Glycolysis does not require oxygen a…
Aug 19, 2020 · 13 shares · 1,094 followersView post →
TK
Tim Kambič
@TimKambic · X
RT @jploenneke: As many of us prepare to lecture on metabolism...here is a nice refresher on lactate
"Glycolysis does not require oxygen a…
Aug 19, 2020 · 13 shares · 232 followersView post →
DH
Dr Paul Head
@DrPHphysio · X
RT @jploenneke: As many of us prepare to lecture on metabolism...here is a nice refresher on lactate
"Glycolysis does not require oxygen a…
Aug 19, 2020 · 13 shares · 1,855 followersView post →
JL
Jeremy Loenneke
@jploenneke · X
As many of us prepare to lecture on metabolism...here is a nice refresher on lactate
"Glycolysis does not require oxygen and has lactate as its end product, because the equilibrium of the LDH reaction is markedly in favor of lactate."
Link: https://t.co/iTz95vwRPk https://t.co/tAfvjc1VfQ
Aug 19, 2020 · 86 likes · 13 shares · 8,594 followersView post →
JW
Jacob de Wolff
@jfdwolff · X
@Jopo_dr Based on my recent reading, true perfusion issues are truly quite rare.
What is your source for Krebs cycle inhibition? Not mentioned in the 38-page masterpiece at https://t.co/4bufyQMXb2 @EJAP_official
I've always been fascinated by the ____ molecule?
For me: it's lactate.
Sharing this recent (ish), excellent review on this long debated/misunderstood molecule:
https://t.co/80V5EMiIlL
#science #chemistry #fangirl
Aug 15, 2020 · 2 likes · 1,999 followersView post →
JE
Jon Easdown
@joneasdown · X
RT @skppowers: Excellent review for students of exercise physiology " Lactate metabolism: historical context, prior misinterpretations, and…
Lactate metabolism: historical context, prior misinterpretations, and current understanding https://t.co/j4J8VznUFX Heavy in some places, interesting almost all.
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 30, 2019 · 39 shares · 284 followersView post →
GT
Guillaume Toffoli
@toffoli_g · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 29, 2019 · 39 shares · 123 followersView post →
MK
Mark Kramer
@MarkBio85 · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 29, 2019 · 39 shares · 294 followersView post →
W
wattsnow
@wattsnow · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 29, 2019 · 39 shares · 1,411 followersView post →
JG
João Gesser
@joaogesser · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 29, 2019 · 39 shares · 281 followersView post →
LP
Lopez-Grueso,R (PhD)
@LopezGrueso_R · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 29, 2019 · 39 shares · 680 followersView post →
MB
Michael Black
@mlennonblack · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 29, 2019 · 39 shares · 88 followersView post →
TT
Tiago Turnes
@TiagoTurnes · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 29, 2019 · 39 shares · 152 followersView post →
IP
Iñaki de la Parra
@inaki_delaparra · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 29, 2019 · 39 shares · 7,945 followersView post →
HV
Hamid Sohrabi (Personal Views)
@HamidRSohrabi · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 28, 2019 · 39 shares · 661 followersView post →
GB
Gorka Prieto-Bellver
@GPrietoBellver · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 27, 2019 · 39 shares · 1,161 followersView post →
C
Chris
@mulleredimages · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 27, 2019 · 39 shares · 635 followersView post →
MP
Matt McAllister, PhD
@MJM_PhD · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 27, 2019 · 39 shares · 246 followersView post →
MA
Matevz Arcon
@Mat_Arcon · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 27, 2019 · 39 shares · 151 followersView post →
FŞ
Feran Şensua
@EmekliHarbiyeli · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 27, 2019 · 39 shares · 343 followersView post →
RC
Raúl Celdrán
@NTSAcademia · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 27, 2019 · 39 shares · 3,086 followersView post →
OH
Omar Hammouda
@HammoudaOm · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 27, 2019 · 39 shares · 805 followersView post →
JP
Jeremiah Peiffer
@JeremiahPeiffer · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 26, 2019 · 39 shares · 506 followersView post →
SS
Samarita Beraldo Santagnello
@SamaritaBeraldo · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 26, 2019 · 39 shares · 36 followersView post →
SB
Silvestre Cardiel Gutiérrez, BS
@SilvestreGtz · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 26, 2019 · 39 shares · 78 followersView post →
AI
Allan Inoue
@Allan_Inoue · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 26, 2019 · 39 shares · 226 followersView post →
AL
Andreas Kreutzer, PhD, CSCS, LSSWB
@akreutzer82 · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 26, 2019 · 39 shares · 517 followersView post →
RS
Ragul Selvamoorthy
@ragul_95 · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 26, 2019 · 39 shares · 376 followersView post →
VT
Víctor Toro
@victortoro96 · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 26, 2019 · 39 shares · 769 followersView post →
JT
John Thyfault (TeeFo)
@john_thyfault · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 26, 2019 · 39 shares · 2,512 followersView post →
NC
Nick J. Siekirk, Ph.D., M.S., CSCS
@nsiekirk · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 26, 2019 · 39 shares · 505 followersView post →
ED
Eric Rawson, Ph.D.
@EricRawsonPhD · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 26, 2019 · 39 shares · 7,535 followersView post →
RK
Rich Kingston
@RichKingston73 · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 26, 2019 · 39 shares · 1,019 followersView post →
LT
Luca T
@QuiteLT · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 26, 2019 · 39 shares · 367 followersView post →
BD
Bryan Jasker PT, DPT
@oval_MetFlex · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 26, 2019 · 39 shares · 610 followersView post →
GE
Gregor Eichhorn
@greichhorn · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 26, 2019 · 39 shares · 361 followersView post →
SM
Salaheddin Sharif, MBChB, PhD, MS
@salaymo · X
RT @jploenneke: Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis…
Aug 26, 2019 · 39 shares · 194 followersView post →
JL
Jeremy Loenneke
@jploenneke · X
Those teaching bioenergetics this semester...may want to consider this paper on lactate being the end product of glycolysis
Link: https://t.co/bYHHqvn8dL
Video: Professor George Brooks on lactate https://t.co/E9006m0cde https://t.co/7N5OuVykbM
Aug 26, 2019 · 170 likes · 39 shares · 8,594 followersView post →
CP
Christopher Perry PhD
@ChrisPerryMito · X
RT @mitokanedria: Proud to have contributed to this collaborative effort:
#Lactate metabolism: historical context, prior misinterpretations…
Feb 25, 2019 · 16 shares · 3,452 followersView post →
KC
Kelly Pritchett, PhD, RDN, CSSD
@KPritchettRD · X
#Lactate metabolism: historical context, prior misinterpretations, and current understanding https://t.co/J6cjDJXtdt
RT @jploenneke: Trying to wrap your head around "lactate is always the end product of glycolysis"
try these two papers (figure from second…
Jan 22, 2019 · 6 shares · 367 followersView post →
DA
Darren Delaney, MSc ASCC
@DarDelFitness · X
RT @jploenneke: Trying to wrap your head around "lactate is always the end product of glycolysis"
try these two papers (figure from second…
Jan 22, 2019 · 6 shares · 372 followersView post →
PP
Paulo Azevedo PhD
@paulohsmazevedo · X
RT @jploenneke: Trying to wrap your head around "lactate is always the end product of glycolysis"
try these two papers (figure from second…
Jan 22, 2019 · 6 shares · 1,123 followersView post →
SC
Sean M. Collins
@SMCollinsPhD · X
RT @jploenneke: Trying to wrap your head around "lactate is always the end product of glycolysis"
try these two papers (figure from second…
Jan 22, 2019 · 6 shares · 490 followersView post →
JL
Jeremy Loenneke
@jploenneke · X
Trying to wrap your head around "lactate is always the end product of glycolysis"
try these two papers (figure from second link)
https://t.co/GpJX2eAqrB
https://t.co/bYHHqv5xmd https://t.co/GqAV1Il14W
Jan 22, 2019 · 26 likes · 6 shares · 8,594 followersView post →
N
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