It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Arc can form virus-like capsids (https://t.co/U7mBob0xwM). I'm super excited about a collaboration with @BriggsGroup, see this preprint https://t.co/K9rPIjYZIo /1
The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer.
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Jan 2019 – Mar 2025Where it's discussed
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X / Twitter88 posts
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News62 articles
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Facebook28 posts
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AI synopsis
What people are saying
The posts demonstrate strong interest and engagement through phrases like 'crazy biology' and 'nervous system is magic,' acknowledging the innovative aspects of Arc's viral-like functions. Supportive comments and references to foundational work exemplify high agreement and perceived high impact, emphasizing the transformative potential of these findings in neuroscience.
Most discussions highlight fascination and support for the significance of the findings, viewing Arc's viral origins as groundbreaking.
The posts show high curiosity, with many referencing the novelty and implications of the research.
Many discussions delve into detailed mechanisms, such as virus-like capsid formation and intercellular RNA transfer, indicating deep engagement.
The majority perceive this discovery as highly impactful, potentially changing our understanding of neural communication and memory formation.
Abstract in brief
- Arc is crucial for the brain's ability to store long-term information and is linked to synaptic plasticity and neurodevelopmental disorders.
- The study reveals that Arc can form virus-like structures, encapsulating RNA and facilitating its transfer to other cells via extracellular vesicles.
- Evolutionarily, Arc is identified as a descendant of retrotransposons, suggesting that retroviral proteins have been adapted for communication between neurons.
Top posts
Most liked on X and Bluesky"The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer" https://t.co/yrzw2kma3a https://t.co/JULg2PwzdW
The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer www.cell.com/cell/pdf/S00...
@ravenscimaven @bnjm Yeah! Here’s the original paper: https://t.co/G5bJwHbCvv
@zhangf mentions foundational work by @JasonSynaptic on Arc for the first story https://t.co/ldH9OlcCaR
I'm late on this, but OMG. The nervous system is magic! The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer https://t.co/7LNJDtq3pX
All mentions
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No mRNA in the food supply---that's totally insane: Paying attention to the neuroendocrinology statements: Read #1 then read #2 --looks like major FAFO to me. >>> 1) The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates
@electroheadfx Voilà un article sur la protéine Arc, un ancien gène viral qui forme des capsules dans nos synapses, et s'avère crucial dans le processus d'apprentissage: https://t.co/3bv5kGxx0n
https://t.co/CQs32EExpW "The neuronal gene Arc encodes a protein that forms virus-like capsids" "Endogenous Arc protein is released from neurons in extracellular vesicles (EVs)"
The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer: Cell https://t.co/bLOokv2Juz
The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer: Cell https://t.co/7GksrBQdUD
@ravenscimaven @bnjm Yeah! Here’s the original paper: https://t.co/G5bJwHbCvv
The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer www.cell.com/cell/pdf/S00...
This week's paper: https://t.co/IxP7CuDzMa
@zhangf mentions foundational work by @JasonSynaptic on Arc for the first story https://t.co/ldH9OlcCaR
@skepteis And then we enslaved them for our purposes
@jasonsynaptic selected pubs https://t.co/jCfohyCXDN https://t.co/RR2low1xbg https://t.co/TpoZInXbLA The waiting room opens 15 min prior to the event! 2/4
The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer https://t.co/WaH2znVoID
RT @whitequark: "The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer" https://t…
https://t.co/xvpOTr7kyv The protein that allows us to form memories was likely a simple virus that got absorbed into early animal cells much like mitochondria has bacterial origins.
RT @elsa_rodarte: The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer https://t…
The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer https://t.co/iVhYHjnQvR
@rdouglasfields1 @QuantaMagazine @ScienceMagazine Fantastic article doc, and speaking of Lamarckian neural processes... https://t.co/Hiqh6BBZtf
@SimsYStuart @SteveStuWill @WiringTheBrain "Arc protein is released from neurons in extracellular vesicles that mediate the transfer of Arc mRNA into new target cells, where it can undergo activity-dependent translation. Arc capsids are able to transfer Arc mRNA into the cytoplasm of neurons." https://t.co/Hiqh6BBZtf
@kimrase @edamame0811 内在化したレトロのタンパク質が機能しているという報告はいくつか出てるけど(例えばhttps://t.co/8cWxzSYRBk)、それがどこまで進化と関連付けられるかは難しい話となる気がする
@iammarjamal https://t.co/tIaCubV871
Det här var ju rätt spännande: hjärnan använder en sorts egna ”virus” för att skicka små meddelanden mellan neuronerna!? https://t.co/VW7yeYaJkw https://t.co/NsWJCRTZW8
RT @whitequark: "The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer" https://t…
RT @whitequark: "The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer" https://t…
RT @whitequark: "The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer" https://t…
RT @whitequark: "The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer" https://t…
RT @whitequark: "The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer" https://t…
RT @whitequark: "The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer" https://t…
RT @whitequark: "The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer" https://t…
"The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer" https://t.co/yrzw2kma3a https://t.co/JULg2PwzdW
@peter_jens @inversedotcom This is the link to the original 2018 Cell paper-https://t.co/sYe4WjbAfN
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
RT @JasonSynaptic: It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Ar…
It's been a hot minute, but you may remember that we discovered some crazy biology, showing that the neuronal protein Arc can form virus-like capsids (https://t.co/U7mBob0xwM). I'm super excited about a collaboration with @BriggsGroup, see this preprint https://t.co/K9rPIjYZIo /1
RT @Stigmehaimatine: The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer: Cell…
The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer: Cell https://t.co/IMgT5gyr0k
RT @Professor_Tong: I'm late on this, but OMG. The nervous system is magic! The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag…
RT @Professor_Tong: I'm late on this, but OMG. The nervous system is magic! The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag…
I'm late on this, but OMG. The nervous system is magic! The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer https://t.co/7LNJDtq3pX
RT @LMB_Library: NEW #LMBpublications The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RN…
NEW #LMBpublications The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer.https://t.co/UKaA7aUYkK
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