Ann Neurol February 2018 PMID 29331091

Terminal spreading depolarization and electrical silence in death of human cerebral cortex.

Jens P Dreier, Sebastian Major, Brandon Foreman, Maren K L Winkler, Eun-Jeung Kang, Denny Milakara, Coline L Lemale, Vince DiNapoli, Jason M Hinzman, Johannes Woitzik, Norberto Andaluz, Andrew Carlson, Jed A Hartings

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Mentions

100

Peak: 15 in Jan 2019

across 6 sources since Jan 2017

Extended reach

2,613,966

potential audience

Total likes

37,219

Video views

2,468,297

Mentions per month

Jan 2017 – Dec 2024

Where it's discussed

News54 articles
X / Twitter25 posts
Facebook8 posts
Blogs6 articles
YouTube5 videos
Reddit2 posts

AI synopsis

What people are saying

The social discussions reveal a fascination with the electrical patterns associated with death, with phrases like 'really interesting' and 'dramatic' conveying curiosity and importance. Some references to technical details and potential implications for understanding death demonstrate a mix of superficial and deeper engagement, while acknowledging that the findings could influence future perspectives on brain death and neurobiological processes.

AgreementModerate agreement

Most discussions show a general agreement with the article's findings, acknowledging the significance of electrical depolarization in understanding death.

InterestHigh interest

Posts display high interest, with many describing the study as 'interesting', 'dramatic', or 'remarkable', indicating engagement with the topic.

EngagementModerate engagement

Several discussions refer to detailed aspects, such as the propagation of depolarizations and their relevance to brain death, demonstrating moderate deep engagement.

ImpactModerate impact

The discussions suggest that this research could influence perspectives on death and neurobiology, but primarily in academic or medical communities, reflecting moderate impact.

Abstract in brief

The study investigates how the human brain responds to severe ischemia during death, finding that electrical silencing (nonspreading depression) occurs simultaneously across brain regions as oxygen levels drop, followed by terminal spreading depolarization that propagates through the brain tissue.
Researchers used brain electrode recordings in patients with irreversible brain injury undergoing terminal extubation and circulatory arrest, revealing that spreading depolarizations typically begin a few minutes after perfusion drops and are closely linked to the final electrical silence.
These findings shed light on the brain's dying process, showing that irreversible damage may be predicted by observing these electrical patterns, which could inform future interventions to extend the window for resuscitation during cerebral ischemia.]

Read the full abstract

All mentions

Understanding the Process of Dying and Near-Death Experiences

Quarks Dimension Ralph · Feb 28, 2023 2,294,472 views

Understanding Brain Activity During Human Death and Reanimation Potential

This study investigates how the human brain responds to severe ischemia during death, revealing electrical silencing occurs simultaneously across regions followed by spreading depolarization, offering insights into…

Vicente Fuentes · May 21, 2018 80,249 views

Brain Response to Severe Ischemia During Death Explored

This study investigates how the human brain responds to severe ischemia during death, showing that electrical silencing occurs simultaneously across brain regions as oxygen drops, followed by spreading depolarization…

Hugo Koffi · Jan 19, 2019 51,557 views

Neuroscience and Characteristics of Near-Death Experiences

This video examines near-death and out-of-body experiences using modern neuroscience, debunking supernatural explanations and highlighting their physiological basis. It also compares NDE memories to real and imagined…

The Rational Channel · Jan 18, 2017 32,139 views

What Happens in the Brain During Death Analysis

The death only matters as it makes us reflect on the value of life. This video explores brain responses during the dying process, including electrical silencing and terminal depolarization, based on recent scientific…

La Célula de Purkinje · Nov 1, 2020 9,881 views

Elias

@EliasBellache · X

@Sara_Imari I would say wholsale electric depolarization of the cells in the body is a good definition of death. Life is when electric potential is maintained across the body. The nervous system being one of the most important parts. https://t.co/7yGD0Cl6uB

Dec 20, 2024 · 103 followers View post →

森井 yms 裕

@yymolly · X

https://t.co/9Z9T9oxVCe (2018年の論文) https://t.co/KPD8ZJsgL9

Feb 26, 2022 · 2 likes · 627 followers View post →

内田

@uchida_kawasaki · X

死の間際、人間の脳内では「脳津波」が広がっていることが判明 : カラパイア https://t.co/PkK01oMVvy https://t.co/23PAfXbEi4

Jan 9, 2022 · 1 like · 1,936 followers View post →

ryo694

@ryo694 · X

Terminal spreading depolarization and electrical silence in death of human cerebral cortex - Dreier - 2018 - Annals of Neurology - Wiley Online Library https://t.co/Q8P6rOm9py

Jan 9, 2022 · 1,384 followers View post →

Markus Riessland

@RiesslandLab · X

Jan 7, 2022 · 5 likes · 185 followers View post →

DocMendizabal

@DocMendizabal · X

¿Cuándo morimos realmente? Una nueva investigación apunta a un "tsunami eléctrico" en la corteza cerebral. https://t.co/I8mcOcoT9a https://t.co/5PREmSehcn

Dec 27, 2021 · 145 followers View post →

Richard Lee Skinner III

@AuthorRichardL · X

@lmcgrew @darrenmwong @Portlandval https://t.co/CPz6bEAeeM Interesting study, a little technical. Talks about electrical patterns of brain as it dies. Makes some interesting conclusions about the a person's death experiences. Spoiler alert. No spooky ghosts.

Jan 19, 2020 · 427 followers View post →

TheFrenchEpidemiologist

@frenchepidemio · X

Vidéo étonnante (et un peu glauque) de 5 min avant la mort d'un patient par électrocoticographie : vague de depolarisation neuronale (relâchement de glutamate et K+) qui se propage à 3 mm/min

Nov 3, 2019 · 4 likes · 15,171 followers View post →

えすてぃーけー

@satokei_1999 · X

ここで定義できる死は死ではないならば死とは何なのか。 https://t.co/vsE0NmkkCe

Apr 28, 2019 · 1 like · 323 followers View post →

@RDcockaroaches · X

RT @NadiasChicken: @RDcockaroaches Heres the study. It's kind of a hard read, but I think it's worth a read. https://t.co/0k7mb2ETzq

Feb 10, 2019 · 1 share · 1,357 followers View post →

THECHICKEN

@NadiasChicken · X

@RDcockaroaches Heres the study. It's kind of a hard read, but I think it's worth a read. https://t.co/0k7mb2ETzq

Feb 9, 2019 · 1 share · 1 followers View post →

NICIS America

@NicisAmerica · X

#NICIS_America speaker, Jed A. Hartings, co-authored this article on the #neurobiology of dying Come hear him speak on "#Pathophysiology and impact of cortical spreading depolarization" this March in Washington DC https://t.co/NU53bfifCW

Jan 23, 2019 · 30 followers View post →

Freezon14

@Freezon14 · X

J'aime une vidéo @YouTube : "QUAND ON M EURT - KESKISPASS #1" à l'adresse https://t.co/9JSVpYsBWw.

Jan 20, 2019 · 461 followers View post →

Ruben

@PerezRubenp96 · X

J'aime une vidéo @YouTube : "QUAND ON M EURT - KESKISPASS #1" à l'adresse https://t.co/Q7ozJBOOVR.

Jan 20, 2019 · 96 followers View post →

Antoine Pezzulo

@warcanum40 · X

J'aime une vidéo @YouTube : "QUAND ON M EURT - KESKISPASS #1" à l'adresse https://t.co/dApD49DmR6.

Jan 20, 2019 · 3 followers View post →

Lexprimer

@LexprimerOff · X

I liked a @YouTube video https://t.co/NTMQRKsmnu QUAND ON M EURT - KESKISPASS #1

Jan 19, 2019 · 103 followers View post →

hugokoffi

@LQCvideos · X

RT @LQCvideos: NOUVEAU CONCEPT SUR LA CHAÎNE PERSO ✌️ QU'EST CE QUI SE PASSE.. #1 ➡️ Quand on meurt ☠️ J'ai choisi le meilleur sujet pour…

Jan 19, 2019 · 5 shares · 58,070 followers View post →

#HC |:|

@Rexianyce · X

RT @LQCvideos: NOUVEAU CONCEPT SUR LA CHAÎNE PERSO ✌️ QU'EST CE QUI SE PASSE.. #1 ➡️ Quand on meurt ☠️ J'ai choisi le meilleur sujet pour…

Jan 19, 2019 · 5 shares · 735 followers View post →

Alexandre Lenoir

@lenoir_alex · X

J'aime une vidéo @YouTube : "QUAND ON M EURT - KESKISPASS #1" à l'adresse https://t.co/dw02HLsJqE.

Jan 19, 2019 · 42 followers View post →

Kevin De Carvalho

@NivekOhlavraced · X

J'aime une vidéo @YouTube : "QUAND ON M EURT - KESKISPASS #1" à l'adresse https://t.co/RXx4lQDC99.

Jan 19, 2019 · 30 followers View post →

Mash

@redfoxsdragon · X

RT @LQCvideos: NOUVEAU CONCEPT SUR LA CHAÎNE PERSO ✌️ QU'EST CE QUI SE PASSE.. #1 ➡️ Quand on meurt ☠️ J'ai choisi le meilleur sujet pour…

Jan 19, 2019 · 5 shares · 1,382 followers View post →

狐 Jun Kiy₪hata 狐

@JunKiyohata · X

J'aime une vidéo @YouTube : "QUAND ON M EURT - KESKISPASS #1" à l'adresse https://t.co/5tUiDnhRp4.

Jan 19, 2019 · 75 followers View post →

lili⋆

@CallmeLysa · X

RT @LQCvideos: NOUVEAU CONCEPT SUR LA CHAÎNE PERSO ✌️ QU'EST CE QUI SE PASSE.. #1 ➡️ Quand on meurt ☠️ J'ai choisi le meilleur sujet pour…

Jan 19, 2019 · 5 shares · 4,666 followers View post →

Nathan Balez

@Nathanbalez2001 · X

RT @LQCvideos: NOUVEAU CONCEPT SUR LA CHAÎNE PERSO ✌️ QU'EST CE QUI SE PASSE.. #1 ➡️ Quand on meurt ☠️ J'ai choisi le meilleur sujet pour…

Jan 19, 2019 · 5 shares · 185 followers View post →

hugokoffi

@LQCvideos · X

NOUVEAU CONCEPT SUR LA CHAÎNE PERSO ✌️ QU'EST CE QUI SE PASSE.. #1 ➡️ Quand on meurt ☠️ J'ai choisi le meilleur sujet pour commencer

Jan 19, 2019 · 27 likes · 5 shares · 58,070 followers View post →

Terminal spreading depolarization and electrical silence in death of human cerebral cortex.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Understanding the Process of Dying and Near-Death Experiences

Understanding Brain Activity During Human Death and Reanimation Potential

Brain Response to Severe Ischemia During Death Explored

Neuroscience and Characteristics of Near-Death Experiences

What Happens in the Brain During Death Analysis