Front Endocrinol (Lausanne) December 2017 PMID 29375474

Recent Advances in Thyroid Hormone Regulation: Toward a New Paradigm for Optimal Diagnosis and Treatment.

Rudolf Hoermann, John E M Midgley, Rolf Larisch, Johannes W Dietrich

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Mentions

14
Peak: 4 in Dec 2023
across 4 sources since Jul 2022

Extended reach

7,895
potential audience

Total likes

184

Video views

7,784

Mentions per month

Jul 2022 – Feb 2025

Where it's discussed

  • Reddit10 posts
  • YouTube2 videos
  • Bluesky1 posts
  • Facebook1 posts

AI synopsis

What people are saying

The discussions reveal a nuanced stance where posters acknowledge the advancements while critiquing oversimplified interpretations, such as the idea that TSH alone shouldn't define thyroid health, exemplified by phrases like 'not a universal measure' and references to the complex, individual variability in thyroid regulation; the tone combines scientific critique with a recognition of the need for personalized approaches.

AgreementModerate agreement

Most discussions express moderate agreement with the article's insights, acknowledging its limitations while recognizing the importance of shifting beyond TSH as a sole indicator.

InterestHigh interest

Posts demonstrate high interest by engaging thoughtfully with the topic, mentioning concepts like personalized diagnosis and critiquing traditional measures.

EngagementModerate engagement

Posts show moderate engagement, with some analyzing the scientific reasoning and calling for nuanced approaches rather than outright acceptance or dismissal.

ImpactModerate impact

The discussions suggest the article could influence current clinical perspectives, pushing for a more individualized understanding of thyroid regulation.

Abstract in brief

  • The relationship between TSH and thyroid hormones (like FT4 and T3) is complex and varies between individuals, making it difficult to rely solely on traditional lab ranges for diagnosis and treatment.
  • Current criteria for diagnosing subclinical thyroid dysfunction are primarily laboratory-based and do not align well with personalized treatment strategies, especially in cases like aging, obesity, or during thyroid hormone therapy.
  • A new approach should recognize that TSH is not always a simple indicator of thyroid health; instead, understanding the unique, dynamic, and adaptive interactions in each person's thyroid regulation system is essential for accurate diagnosis and effective treatment.]

Top posts

Most liked on X and Bluesky
Johannes W. Dietrich
@drjwdietrich.bsky.social · Bluesky

Generally, I agree, and this study has, in fact, several shortcomings. However, demanding that TSH be equal in both groups would imply that it is a universal measure of thyroid signalling, which is incorrect in light of current evidence. pubmed.ncbi.nlm.nih.gov/29375474/ doi.org/10.3389/fend...

Feb 8, 2025 · 1 share View post →

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Johannes W. Dietrich
@drjwdietrich.bsky.social · Bluesky

Generally, I agree, and this study has, in fact, several shortcomings. However, demanding that TSH be equal in both groups would imply that it is a universal measure of thyroid signalling, which is incorrect in light of current evidence. pubmed.ncbi.nlm.nih.gov/29375474/ doi.org/10.3389/fend...

Feb 8, 2025 · 1 share View post →
Naltrexone/Wellbutrin for weight loss : r/LowDoseNaltrexone
Reddit

https://www.frontiersin.org/articles/10.3389/fendo.2017.00364/full. LDN and Thyroid Disorders... Kent Holtorf, M.D.. https://ldnresearchtrust ...

Feb 6, 2024 View →
Mindig fázol? : r/LowDoseNaltrexone - Reddit
Reddit

... 10.3389/fendo.2017.00364/full. LDN és pajzsmirigybetegségek... Kent Holtorf, M.D. https://ldnresearchtrust.org/sites/default/files/inline ...

Dec 5, 2023 View →
Sürekli üşüyor musun? : r/LowDoseNaltrexone
Reddit

... 10.3389/fendo.2017.00364/full. LDN ve Tiroid Bozuklukları... Kent Holtorf, M.D. https://ldnresearchtrust.org/sites/default/files/inline-files ...

Dec 5, 2023 View →
Feeling cold all the time? : r/LowDoseNaltrexone
Reddit

https://www.frontiersin.org/articles/10.3389/fendo.2017.00364/full. LDN and Thyroid Disorders... Kent Holtorf, M.D.. https://ldnresearchtrust ...

Dec 5, 2023 View →
Постоянно мерзнете? : r/LowDoseNaltrexone
Reddit

... 10.3389/fendo.2017.00364/full. LDN и заболевания щитовидной железы... Kent Holtorf, M.D. https://ldnresearchtrust.org/sites/default/files ...

Dec 5, 2023 View →
LDN and hypothyroidism : r/LowDoseNaltrexone
Reddit

https://www.frontiersin.org/articles/10.3389/fendo.2017.00364/full. LDN and Thyroid Disorders Kent Holtorf, M.D.. FM, ME/CFS mentioned also.

Jun 7, 2023 View →
LDN và suy giáp : r/LowDoseNaltrexone - Reddit
Reddit

... 10.3389/fendo.2017.00364/full. LDN và rối loạn tuyến giáp Kent Holtorf, M.D. FM, ME/CFS cũng được đề cập https://ldnresearchtrust.org/sites ...

Jun 7, 2023 View →
Bin mir nicht sicher, ob das die Antwort ist. : r/LowDoseNaltrexone
Reddit

... 10.3389/fendo.2017.00364/full LDN und Schilddrüsenerkrankungen Kent Holtorf, M.D. FM, ME/CFS ebenfalls erwähnt https://ldnresearchtrust ...

May 12, 2023 View →
Not sure if this is the answer : r/LowDoseNaltrexone
Reddit

https://www.frontiersin.org/articles/10.3389/fendo.2017.00364/full. LDN and Thyroid Disorders Kent Holtorf, M.D.. FM, ME/CFS mentioned also

May 12, 2023 View →
Hvor bør ens tal ligge når man er medicineret med euthyrox? Hvad ...
Facebook

org/articles/10.3389/fendo. 2017.00364/full · No photo description available. 3 yrs. Liv Stang-Lund. Heidi Løvhøj Larsen Så må du vise meg ...

Sep 14, 2022 View →
Do any of you skip days? : r/LowDoseNaltrexone
Reddit

https://www.frontiersin.org/articles/10.3389/fendo.2017.00364/full. LDN and Thyroid Disorders... Kent Holtorf, M.D.. FM, ME/CFS mentioned also.

Jul 27, 2022 View →