PubHawk
January 2018 PMID 29383573

Fatigue in Patients with Major Depressive Disorder: Prevalence, Burden and Pharmacological Approaches to Management.

Helia Ghanean, Amanda K Ceniti, Sidney H Kennedy

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Mentions

104
Peak: 15 in Mar 2022
across 4 sources since Mar 2019

Extended reach

7,700,481
potential audience

Total likes

300,893

Video views

7,552,503

Mentions per month

Mar 2019 – Sep 2025

Where it's discussed

  • X / Twitter74 posts
  • News17 articles
  • YouTube11 videos
  • Facebook2 posts

AI synopsis

What people are saying

The discussions reveal a strong connection between personal experiences and the themes of the article, highlighted by comments like 'I can relate...' and 'I feel CATACLYSMICALLY called out.' This reflects a genuine engagement with the subject matter. Phrases such as 'it's something very important that we overlook' and repeated references to videos sharing insights about hidden depression indicate concern and a desire for deeper understanding. The tone varies from casual to heartfelt, emphasizing a collective struggle and empathy within the community.

AgreementModerate agreement

Many posts reflect a level of acceptance towards the discussions in the article, recognizing the relevance of fatigue in depression.

InterestHigh interest

There is heightened curiosity as participants connect personal experiences with the wider implications of fatigue discussed in the article.

EngagementModerate engagement

Contributions to the discussions show some depth, with users reflecting on their own experiences and sharing resources, though many remain surface-level.

ImpactHigh impact

Users express that the publication could significantly influence their understanding and support for those dealing with depression.

Abstract in brief

  • Fatigue is a common symptom in over 90% of patients with Major Depressive Disorder (MDD), impacting physical, cognitive, and emotional well-being.
  • The review focuses on pharmacological treatments, highlighting that dopaminergic and noradrenergic medications like modafinil, flupenthixol, and atomoxetine are among the most effective for alleviating fatigue symptoms.
  • Variability in research methods and assessment tools may lead to inconsistent results, and nonpharmacological options such as light therapy and exercise are also considered for managing fatigue in MDD.
Read the full abstract

Top posts

Most liked on X and Bluesky
28calaveritaswa
@28calaveritaswa · X

Mano realmente eres tú, menos la 4 Y dile a tu psicólogo que te haga test de edad mental. https://t.co/ZtzilohNaG

Sep 21, 2025 · 8 likes View post →
Dr Michael Mol
@DrMichaelMol · X

#Fatigue, like stress, has become our "new normal". But it's not normal at all. Stubborn fatigue can sometimes be a symptom of a bigger issue, like a mental health condition. Chronic fatigue occurs in 90% of those with #depression https://t.co/74ksICSoWo

Apr 28, 2020 · 5 likes · 3 shares · 23,832 followers View post →
Dr Michael Mol
@DrMichaelMol · X

#Fatigue (like stress) has become our "new normal" - but it's not normal at all. Stubborn fatigue can sometimes be a symptom of a bigger issue, like a mental health condition. Lingering fatigue occurs in 90% of those with #depression https://t.co/74ksICSoWo

Jul 31, 2020 · 3 likes · 2 shares · 23,832 followers View post →
Dr Michael Mol
@DrMichaelMol · X

#Fatigue, like stress, has become our "new normal". But it's not normal at all. Stubborn fatigue can sometimes be a symptom of a bigger issue, like a mental health condition. Chronic fatigue occurs in 90% of those with #depression https://t.co/74ksICSoWo

Mar 21, 2019 · 3 likes · 4 shares · 23,832 followers View post →
─═♡⁀➷
@00yol14_ · X

La vida actual de Takemichi y Mikey

Feb 10, 2023 · 3 likes · 1 share · 391 followers View post →
Aldo Nueve - Genuinamente Cansado de la Vida
@Twitty_Aldo · X

@lankaden https://t.co/BFLjdQ2ia6

Mar 17, 2025 · 3 likes · 341 followers View post →

All mentions

28calaveritaswa
@28calaveritaswa · X

Mano realmente eres tú, menos la 4 Y dile a tu psicólogo que te haga test de edad mental. https://t.co/ZtzilohNaG

Sep 21, 2025 · 8 likes View post →
Gigi el desesperado por afecto
@Gigiesgod · X

Debería ir con mi psiquiatra, no me gustaría afirmar que tengo depresión solo por un pinche video que acabo de ver. Voy a ver pa cuando consigo una consulta. Por cierto el video que vi es este: https://t.co/dMMohKHEqq

Sep 21, 2025 · 1,011 followers View post →
lumia.
@youkai_on · X

https://t.co/ufrgYSk5cu why do i relate to this

Sep 20, 2025 · 2 likes · 39 followers View post →
DxRazielxD de RURU
@DiegoAr65710562 · X

Empatía, espero ser de apoyo y también encontralo https://t.co/0JYIR9PmWK

Mar 29, 2025 · 4 followers View post →
Aldo Nueve - Genuinamente Cansado de la Vida
@Twitty_Aldo · X

@lankaden https://t.co/BFLjdQ2ia6

Mar 17, 2025 · 3 likes · 341 followers View post →
Nyx
@nyx_is_nb_perso · X

Reminder https://t.co/nQ7Y4gsRAy

Dec 30, 2024 · 41 followers View post →
Lep in the Hood ('Parody' according to Elon Musk)
@LepintheHood · X

Important! - Signs Someone Fakes Being Ok https://t.co/JRdaK2t7Hs

Dec 16, 2024 · 3,166 followers View post →
wonder_brother_
@wonder_brother_ · X

❤️[¡buenas noches, descansen! ¡los quiero mucho a todos!]

Jul 18, 2024 · 1 like · 1,332 followers View post →
MrHayate
@HayateUSJP · X

Imagine that it has been this way from junior high school all the way to today. And it is much worse than it was back then when the worst problems I experienced were happening. https://t.co/jC9iU59LyI

May 30, 2024 · 222 followers View post →
Owen Carter
@OwenCarter7 · X

https://t.co/53E06HsVe3

May 13, 2024 · 90 followers View post →
.darkmin745
@ZalgadoPab90912 · X

6 señales de que alguien FINGE estar BIEN (pero sufre interiormente) https://t.co/Oxqoii5K3J via @YouTube así me siento

May 10, 2024 · 1 like · 18 followers View post →
Lauleena Harvey
@Lauleena_Harvey · X

6 Signs Someone Fakes Being OK https://t.co/CFrl1TwUAJ via @YouTube

Feb 11, 2024 · 59 followers View post →
partidario zombi
@PartidarioZ · X

RT @YastMe: Es posible que se me hayan saltado un par de lágrimas viendo esto, porque es bastante cierto. Altamente recomendable verlo, igu…

Oct 7, 2023 · 1 share · 171 followers View post →
LVY Ahos
@Lvy_ahos · X

https://t.co/GHdi3RhwyM

Sep 1, 2023 · 174 followers View post →
Sammy
@Samletemily__ · X

@Psych2go yo…. Omori reference? https://t.co/unayeKWgPr https://t.co/IoO2SdvKFI https://t.co/7aF57MkDPL

Aug 18, 2023 · 11 followers View post →
YastMe
@YastMe · X

Es posible que se me hayan saltado un par de lágrimas viendo esto, porque es bastante cierto. Altamente recomendable verlo, igual os dais cuenta de que alguien de vuestro entorno (o vosotros mismos) está en una situación no precisamente ideal https://t.co/EfBhB15wwp

Aug 15, 2023 · 2 likes · 1 share · 223 followers View post →
Anaïse Ory
@Ana_the_cat · X

https://t.co/BAuUnnSBvO

Aug 1, 2023 · 475 followers View post →
96matcha
@96matchaa · X

https://t.co/E35wpfgagp

Jul 18, 2023 · 450 followers View post →
amenum
@papy_amenum · X

6 signes qu'une personne fait SEMBLANT D'ALLER BIEN (mais souffre à l'in... https://t.co/NwWpnw3CFF

Jul 16, 2023 · 85 followers View post →
Javier
@Riku_Nakama · X

Me siento identificado https://t.co/CE4qJCHk8M

Jul 13, 2023 · 77 followers View post →
Sapiencia Práctica
@SapienciaPrcti1 · X

Tener poca energía no es un problema infrecuente, pero sigue siendo duro lidiar con el agotamiento continuo. Pero, ¿qué puede ser lo que te hace sentir cansado todo el tiempo? Vídeo en YouTube: https://t.co/XzVOahK9DI #SapienciaPractica #cansancio https://t.co/njCSA0I9IV

Jul 13, 2023 · 1 like · 39 followers View post →
JustRuka
@JustRukaaa · X

https://t.co/bScotSyb8N I feel CATACLYSMICALLY called out.

Apr 24, 2023 · 35 followers View post →
Mike (ミケ_真咲)
@Kaminoyoni404 · X

Holy shit, it's my early high school self. https://t.co/PHyQDeyn81

Apr 15, 2023 · 246 followers View post →
びーふぁ。@Be-fa
@InazumaSakuraTF · X

https://t.co/UIPBBnBvmy

Apr 11, 2023 · 1,966 followers View post →
─═♡⁀➷
@00yol14_ · X

RT @00yol14: La vida actual de Takemichi y Mikey

Feb 11, 2023 · 1 share · 391 followers View post →
─═♡⁀➷
@00yol14_ · X

La vida actual de Takemichi y Mikey

Feb 10, 2023 · 3 likes · 1 share · 391 followers View post →
Kirei Na ~ | Commissions/Tattoos Open
@Kireinoyuri · X

https://t.co/TF8bK9lE0n

Jan 11, 2023 · 1 like · 717 followers View post →
CATRY GHISLAINE
@CatryGhislaine · X

Très bonne vidéo sur la dépression masquée. Comment l'identifier, comment aider efficacement ? Cela concerne beaucoup de personnes, souvent en fin d'automne et avec le manque de luminosité ✨️

Nov 29, 2022 · 1 like · 77 followers View post →
Chez SandRock
@chez_sandrock · X

Regardez "6 signes qu'une personne fait SEMBLANT D'ALLER BIEN (mais souffre à l'intérieur)" sur YouTube https://t.co/YG0Y5hPL8D

Nov 28, 2022 · 610 followers View post →
Javier au Barca
@Jakyred_ · X

https://t.co/uTrR55TJie

Nov 16, 2022 · 1 like · 157 followers View post →
Kathvavi
@kathe_vsquez · X

https://t.co/na2BKwOViv

Oct 17, 2022 · 953 followers View post →
off
@kaitoshion0132 · X

6 señales de que alguien FINGE estar BIEN (pero sufre interiormente) https://t.co/HyqnbKofkH a través de @YouTube

Sep 3, 2022 · 145 followers View post →
Dios es Amor
@Perla000_ · X

6 señales de que alguien FINGE estar BIEN (pero sufre interiormente) https://t.co/YwTAhgzVRm a través de @YouTube

Aug 1, 2022 · 1 like · 1,125 followers View post →
Dr Michael Mol
@DrMichaelMol · X

#Fatigue, like stress, has become our "new normal". But it's not normal at all. Stubborn fatigue can sometimes be a symptom of a bigger issue, like a mental health condition. Chronic fatigue occurs in 90% of those with #depression https://t.co/74ksICSoWo

Jul 29, 2022 · 1 like · 23,832 followers View post →
Clepanto
@clepanto · X

Yo sé que estoy con depresión, pero este video dice que he tenido depresión toda la vida ¬¬ https://t.co/782klc2FKX

Jul 15, 2022 · 2,792 followers View post →
ByAnt121
@ByAnt121 · X

6 señales de que alguien FINGE estar BIEN (pero sufre interiormente) https://t.co/yPkRyfWZfk vía @YouTube Esta bastante bien este video

Jul 14, 2022 · 117 followers View post →
kenndall channel jenner
@channel_jenner · X

6 señales de que alguien FINGE estar BIEN (pero sufre interiormente) https://t.co/T6sLl5mJEK via @YouTube

Jun 21, 2022 · 1 like · 20 followers View post →
♪Tokki♪
@Evocativa · X

https://t.co/e2qHht2iH8

Jun 20, 2022 · 1 like · 498 followers View post →
林
@cyslin24 · X

6 Signs Someone Fakes Being OK https://t.co/mqBJ05lhTN via @YouTube

Jun 7, 2022 · 36 followers View post →
Spookrys season
@niimenii_ · X

https://t.co/cJbwTelTrP El masking en la depresión o depresión camuflada en 7 minutos, pero quizás ayude a comprendernos un poquito más.

May 21, 2022 · 447 followers View post →
Moredhel0
@Moredhel0 · X

Can someone tell me how much paranoia is appropriate, when youtube suddenly suggests this video: https://t.co/KX9DmgmsXY bonus information: my doctor agreed with youtube and prescribed an antidepressant.

May 20, 2022 · 611 followers View post →
Envy1359 (The Modern Envy)
@EnvyHomunculus1 · X

This boy featured in this video's thumbnail and topic by Psych2Go kinda looks like Pride but with a little plant on his head. As if Pride is not feeling "OK". https://t.co/hGXHgwCkxz

May 19, 2022 · 44 followers View post →
Stephan_ilie
@Ilie_Stephan · X

6 Signs Someone Fakes Being OK https://t.co/uqx9xUE1t3 via @YouTube

May 16, 2022 · 44 followers View post →
yolo.... :3
@yolo_cas · X

6 señales de que alguien FINGE estar BIEN (pero sufre interiormente) https://t.co/bfRkEzyMFY via @YouTube

May 16, 2022 · 3 followers View post →
Jessie Doeman
@cretah · X

https://t.co/azBKW6oS72

May 13, 2022 · 21 followers View post →
conchi eixeres pique
@ConchiPiquer · X

6 señales de que alguien FINGE estar BIEN (pero sufre interiormente) https://t.co/fhZi4LMjw6 a través de @YouTube

May 11, 2022 · 103 followers View post →
¡
@InfoBrawl_ · X

Acabo de encontrar este vídeo... Creo que a bastantes personas les hace falta verlo, es algo muy importante que dejamos pasar. Si veis a alguien que creáis que padece alguno de estos síntomas, recordadle que no está sólo, TIENE HOMBRO EN EL QUE APOYARSE! https://t.co/45crBR83Lz

May 7, 2022 · 260 followers View post →
SentiForeveer
@SentiForeveer · X

Acabo de encontrar este vídeo... Creo que a bastantes personas les hace falta verlo, es algo muy importante que dejamos pasar. Si veis a alguien que creáis que padece alguno de estos síntomas, recordadle que no está sólo, TIENE HOMBRO EN EL QUE APOYARSE! https://t.co/8j6pV9bDiW

May 7, 2022 · 224 followers View post →
Snoozles
@snooozieee · X

I can relate... #depression https://t.co/DKKVl2xMnt

May 6, 2022 · 44 followers View post →
Ley03
@yamachuky · X

https://t.co/xb2BPVaTqp

May 5, 2022 · 324 followers View post →
Sapiencia Práctica
@SapienciaPrcti1 · X

Puede haber una depresión subyacente en personas que vemos sonreír o que aparentar esta bien. Porque, cuando escuchas la palabra depresión, ¿piensas automáticamente en un rostro abatido o en una persona sentada sola en un rincón llorando? https://t.co/hxOdcUMLEB https://t.co/9z76kBSc9r

May 2, 2022 · 1 like · 39 followers View post →
Boliin♡
@BolinVelin · X

. https://t.co/dyBZU2m2Zw

Apr 19, 2022 · 1,907 followers View post →
Tommy Fox
@FreakFactor5 · X

6 Signs Someone Fakes Being OK https://t.co/yp3Faft2QM via @YouTube I think it's time I come clean; this video says what I feel pretty well.

Apr 7, 2022 · 1 like · 124 followers View post →
The Learning Curve
@ACCLC · X

Unfortunately, sometimes people are just too good at lying. https://t.co/W0iqnjpY7f

Mar 30, 2022 · 229 followers View post →
초우코유(접률 낮음)
@cho_coOoU · X

구독영상 뒤지다가 우연히 발견한 Omori https://t.co/K9Ift7IUDx

Mar 24, 2022 · 27 followers View post →
IzayaYashiro
@IzayaYashiro · X

6 Signs Someone- https://t.co/dhNUXvzi3W

Mar 22, 2022 · 4 followers View post →
h₹¥x₳Ł៛৳z ꙳ ⅠⅨⅧⅥ
@luqrafmar · X

6 Signs Someone Fakes Being OK https://t.co/Nbr9NhXuJu

Mar 21, 2022 View post →
時序
@shixu_timestory · X

https://t.co/SxL3zEIRLP There are omori references!! This is so well done

Mar 21, 2022 · 1 like · 515 followers View post →
Tiffany Cable
@cripcpyogi · X

6 Signs Someone Fakes Being OK https://t.co/c35rs0axme via @YouTube

Mar 21, 2022 · 160 followers View post →
Nana Carbide《Vtuber》
@nana_carbide · X

6 Signs Someone Fakes Being OK https://t.co/Go9sw8zZz4 via @YouTube

Mar 20, 2022 · 429 followers View post →
esengul
@iclawnicc · X

@viviola1106 EVET BU VIDEOYDU SANIRIM https://t.co/I1GicTMnEO

Mar 20, 2022 · 1 like · 1,218 followers View post →
Decade
@neodukemon · X

https://t.co/KxMmhFsnLT

Mar 20, 2022 · 256 followers View post →
หมั่นโถวห่อเหี่ยวเคี้ยวแล้วติดคอ
@TJ_Swallow_ · X

6 Signs Someone Fakes Being OK https://t.co/As9GdJ5ZvD via @YouTube

Mar 20, 2022 · 28 followers View post →
Leo Saber
@Ruby_Spark1 · X

https://t.co/E6Tc54V2dy

Mar 20, 2022 · 132 followers View post →
Charlie Kruse
@TheCharlieKruse · X

6 Signs Someone Fakes Being OK https://t.co/5PzULS4MD2 via @YouTube

Mar 20, 2022 · 6,155 followers View post →
Moses Biyela
@bhudamose · X

RT @DrMichaelMol: #Fatigue (like stress) has become our "new normal" - but it's not normal at all. Stubborn fatigue can sometimes be a symp…

Jul 31, 2020 · 2 shares · 1,858 followers View post →
Kate Nokwe
@This_Kate · X

RT @DrMichaelMol: #Fatigue (like stress) has become our "new normal" - but it's not normal at all. Stubborn fatigue can sometimes be a symp…

Jul 31, 2020 · 2 shares · 14,179 followers View post →
Dr Michael Mol
@DrMichaelMol · X

#Fatigue (like stress) has become our "new normal" - but it's not normal at all. Stubborn fatigue can sometimes be a symptom of a bigger issue, like a mental health condition. Lingering fatigue occurs in 90% of those with #depression https://t.co/74ksICSoWo

Jul 31, 2020 · 3 likes · 2 shares · 23,832 followers View post →
Skin Renewal SA
@SkinBodyRenewal · X

RT @DrMichaelMol: #Fatigue, like stress, has become our "new normal". But it's not normal at all. Stubborn fatigue can sometimes be a sympt…

Apr 28, 2020 · 3 shares · 3,053 followers View post →
fazlin
@FazlinB · X

RT @DrMichaelMol: #Fatigue, like stress, has become our "new normal". But it's not normal at all. Stubborn fatigue can sometimes be a sympt…

Apr 28, 2020 · 3 shares · 109 followers View post →
Dr Michael Mol
@DrMichaelMol · X

#Fatigue, like stress, has become our "new normal". But it's not normal at all. Stubborn fatigue can sometimes be a symptom of a bigger issue, like a mental health condition. Chronic fatigue occurs in 90% of those with #depression https://t.co/74ksICSoWo

Apr 28, 2020 · 5 likes · 3 shares · 23,832 followers View post →
Aimee
@AimeeJasmin · X

RT @DrMichaelMol: #Fatigue, like stress, has become our "new normal". But it's not normal at all. Stubborn fatigue can sometimes be a sympt…

Mar 21, 2019 · 4 shares · 1,186 followers View post →
......
@Slayinmylane · X

RT @DrMichaelMol: #Fatigue, like stress, has become our "new normal". But it's not normal at all. Stubborn fatigue can sometimes be a sympt…

Mar 21, 2019 · 4 shares · 552 followers View post →
Dr Michael Mol
@DrMichaelMol · X

#Fatigue, like stress, has become our "new normal". But it's not normal at all. Stubborn fatigue can sometimes be a symptom of a bigger issue, like a mental health condition. Chronic fatigue occurs in 90% of those with #depression https://t.co/74ksICSoWo

Mar 21, 2019 · 3 likes · 4 shares · 23,832 followers View post →