Front Pharmacol January 2018 PMID 29387009

Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression.

Leor Roseman, David J Nutt, Robin L Carhart-Harris

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Mentions

41
Peak: 12 in Apr 2020
across 4 sources since Jan 2019

Extended reach

215,207
potential audience

Total likes

941

Video views

94,989

Mentions per month

Jan 2019 – Dec 2024

Where it's discussed

  • X / Twitter32 posts
  • Facebook4 posts
  • Reddit3 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions consistently emphasize the significance of the research, with posts referencing specific findings like the link between mystical experiences and depression improvement. The tone is generally supportive and analytical, using phrases like 'great article' and discussing implications for therapy, which demonstrates high engagement and perceived impact of the study.

AgreementStrong agreement

Many discussions explicitly support the findings, emphasizing that the quality of psychedelic experiences predicts positive therapeutic outcomes.

InterestHigh interest

The discussions reflect a high level of interest, referencing multiple studies, and using phrases like 'great article' and 'interesting things,' indicating engagement with the research.

EngagementModerate engagement

Some posts delve into specific aspects of the study, such as its implications for supervised environments and therapy models, showing thoughtful engagement.

ImpactHigh impact

Several users highlight the potential influence of this research on future treatment approaches, signaling that they see it as having substantial importance.

Abstract in brief

  • The study investigated how the quality of psychedelic experiences, specifically Oceanic Boundlessness (OBN) and Dread of Ego Dissolution (DED), predicts long-term improvements in treatment-resistant depression after psilocybin therapy.
  • Results showed that higher levels of mystical-type experiences (OBN) and challenging experiences (DED) during the session were significantly associated with better clinical outcomes at 5 weeks, supporting the idea that the nature of the acute experience influences therapeutic success.
  • Sensory perceptual effects had little to no predictive value, emphasizing that the emotional and mystical components of the psychedelic experience are more critical for long-term depression improvement.

Top posts

Most liked on X and Bluesky
MAPS Canada
@MAPSCanada · X

Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression: This basic principle of psychedelic treatment models - acute experience mediates improvements. @ProfDavidNutt @RCarhartHarris #PSI2020 https://t.co/kd14Vup6D6

Apr 30, 2020 · 24 likes · 7 shares · 12,383 followers View post →
Dinosaurouos
@teriantropio · X

مقالات مفید، رفرنس های خوبی توشون پیدا میکنید و ایده خوبی بهتون میده کارهای آکادمیکِ به روز تو این حوزه چیکار میکنند: https://t.co/FiUiR0jRPs https://t.co/PrQuMimYME https://t.co/5Mu4IomAPf https://t.co/wZOqIxYdGa سایتهای مفید: https://t.co/lFYmRP7CsG https://t.co/ctZbjmiKxH

May 28, 2023 · 23 likes · 2,661 followers View post →
Healing Advocacy Fund
@HealingAdvFund · X

A study on psilocybin therapy found that the quality of an acute psilocybin therapeutic experience predicts the positive treatment outcomes. An implication of this finding is that supervised environments will ensure the best treatment results. Full study: https://t.co/KZZ5XJ11gj https://t.co/BbW6DOZHsc

Sep 27, 2020 · 12 likes · 3 shares · 1,085 followers View post →
Daniel Cohrs, MD
@DanielCohrsMD · X

@hubermanlab @ExistWell And this from @RCarhartHarris (among other studies): https://t.co/tT7d87wuKT

Oct 10, 2022 · 4 likes · 1 share · 702 followers View post →
Sheri Eckert Foundation
@sherifoundation · X

Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression #Psilocybin #therapy #yesonip34 @DrBronner @MAPS @MAPSCanada https://t.co/Z4pUIRaTrw

Apr 29, 2020 · 3 likes · 1 share · 2,312 followers View post →
DecrimNatureDC
@DecrimNatureDC · X

RESEARCH PAPER: "Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression" https://t.co/PDAoekrVsn #DecrimNature

Apr 28, 2020 · 2 likes · 2 shares · 1,095 followers View post →

All mentions

Dinosaurouos
@teriantropio · X

مقالات مفید، رفرنس های خوبی توشون پیدا میکنید و ایده خوبی بهتون میده کارهای آکادمیکِ به روز تو این حوزه چیکار میکنند: https://t.co/FiUiR0jRPs https://t.co/PrQuMimYME https://t.co/5Mu4IomAPf https://t.co/wZOqIxYdGa سایتهای مفید: https://t.co/lFYmRP7CsG https://t.co/ctZbjmiKxH

May 28, 2023 · 23 likes · 2,661 followers View post →
Marc Samet
@marc_samet · X

https://t.co/yYPvPXWrhP

May 10, 2023 · 83 followers View post →
Mark Givens
@ShibbyDissident · X

RT @DanielCohrs5: @hubermanlab @ExistWell And this from @RCarhartHarris (among other studies): https://t.co/tT7d87wuKT

Oct 16, 2022 · 1 share · 2,034 followers View post →
Daniel Cohrs, MD
@DanielCohrsMD · X

@hubermanlab @ExistWell And this from @RCarhartHarris (among other studies): https://t.co/tT7d87wuKT

Oct 10, 2022 · 4 likes · 1 share · 702 followers View post →
Views on Drugs
@ViewsOnDrugsBot · X

RT @ViewsOnDrugsBot: Quality of Acute #Psychedelic Experience Predicts Therapeutic Efficacy of #Psilocybin for Treatment-Resistant Depressi…

Mar 11, 2022 · 1 share · 2,055 followers View post →
Views on Drugs
@ViewsOnDrugsBot · X

Quality of Acute #Psychedelic Experience Predicts Therapeutic Efficacy of #Psilocybin for Treatment-Resistant Depression 1/5 https://t.co/ONIKZMjrrA

Dec 30, 2021 · 1 share · 2,055 followers View post →
Thomas Hesslow
@thomashesslow · X

@OscarTengmark @f_hieronymus @christianruck @ruter_knekt Se t.ex. här: https://t.co/knl0eJ775r

Nov 11, 2021 · 2 likes · 305 followers View post →
NormanFarb
@NormanFarb · X

@NeuroYogacara This one does a lot of interesting things to operationalize the ephemeral in explaining clinical response: https://t.co/oCXjW07YqP

Oct 12, 2021 · 2 likes · 953 followers View post →
SexiRavenRae™ Hollywood/LAs Gold Standard Domme
@SexiRavenRae · X

Here is a great article https://t.co/VgtE6gUWGX

Jul 2, 2021 · 7,896 followers View post →
MANNDella
@PUNC20MANNdella · X

#PUNC20 On Facebook this was a public photo of mine. I reflected upon the T-shirt & how my peers, lectures & employer MIGHT judge my professionalism. It's only a T-shirt right? Please see link to research on

Oct 8, 2020 · 2 likes · 52 followers View post →
Adam Prine for Oregon
@PrineTime · X

RT @voteyeson109: A study on psilocybin therapy found that the quality of an acute psilocybin therapeutic experience predicts the positive…

Sep 27, 2020 · 3 shares · 852 followers View post →
PeaceLoveCrypto.btc
@peacelovecrypt0 · X

RT @voteyeson109: A study on psilocybin therapy found that the quality of an acute psilocybin therapeutic experience predicts the positive…

Sep 27, 2020 · 3 shares · 2,275 followers View post →
Healing Advocacy Fund
@HealingAdvFund · X

A study on psilocybin therapy found that the quality of an acute psilocybin therapeutic experience predicts the positive treatment outcomes. An implication of this finding is that supervised environments will ensure the best treatment results. Full study: https://t.co/KZZ5XJ11gj https://t.co/BbW6DOZHsc

Sep 27, 2020 · 12 likes · 3 shares · 1,085 followers View post →
AlisonMyrden ✌
@AlisonMyrden · X

RT @MAPSCanada: Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression: Thi…

May 2, 2020 · 7 shares · 4,672 followers View post →
Christophe Longpré-Poirier
@LongprePoirier · X

RT @MAPSCanada: Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression: Thi…

Apr 30, 2020 · 7 shares · 180 followers View post →
Ricardo Calvário - History Myths & Legends
@RicardoCalvrio1 · X

RT @MAPSCanada: Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression: Thi…

Apr 30, 2020 · 7 shares · 7,591 followers View post →
Mind Escape Podcast
@MikeEscape · X

RT @MAPSCanada: Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression: Thi…

Apr 30, 2020 · 7 shares · 4,079 followers View post →
Zay
@Zayy127 · X

RT @MAPSCanada: Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression: Thi…

Apr 30, 2020 · 7 shares · 377 followers View post →
Chacruna Institute
@Chacruna_Inst · X

RT @MAPSCanada: Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression: Thi…

Apr 30, 2020 · 7 shares · 12,584 followers View post →
TripsForTheSoul
@Tripsforthesoul · X

RT @MAPSCanada: Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression: Thi…

Apr 30, 2020 · 7 shares · 826 followers View post →
MAPS Canada
@MAPSCanada · X

Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression: This basic principle of psychedelic treatment models - acute experience mediates improvements. @ProfDavidNutt @RCarhartHarris #PSI2020 https://t.co/kd14Vup6D6

Apr 30, 2020 · 24 likes · 7 shares · 12,383 followers View post →
Sheri Bessi-Eckert
@sheriseckert · X

RT @opsbuzz: Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression #Psiloc…

Apr 29, 2020 · 1 share · 20,515 followers View post →
Sheri Eckert Foundation
@sherifoundation · X

Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression #Psilocybin #therapy #yesonip34 @DrBronner @MAPS @MAPSCanada https://t.co/Z4pUIRaTrw

Apr 29, 2020 · 3 likes · 1 share · 2,312 followers View post →
Tokin’ Southerner
@Hemp4Victory · X

RT @DecrimNatureDC: RESEARCH PAPER: "Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resi…

Apr 28, 2020 · 2 shares · 2,402 followers View post →
DecrimNatureDC
@DecrimNatureDC · X

RESEARCH PAPER: "Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression" https://t.co/PDAoekrVsn #DecrimNature

Apr 28, 2020 · 2 likes · 2 shares · 1,095 followers View post →
Symmetrical Data Security, LLC.
@SymDataSec · X

Quality of acute experience predicts therapeutic efficacy of psilocybin https://t.co/cYK6NGx32d Introduction Psychedelic therapy may be more appropriately thought of as a distinct form of (drug-assisted) psychotherapy than as a pure pharmacotherapy. P… https://t.co/fENKF0tFnG

Jan 2, 2020 · 2,813 followers View post →
Angsuman Chakraborty ✪
@angsuman · X

Quality of acute experience predicts therapeutic efficacy of psilocybin https://t.co/dPcOvs9N06

Jan 2, 2020 · 7,508 followers View post →
Hacker News 150
@newsyc150 · X

Quality of acute experience predicts therapeutic efficacy of psilocybin https://t.co/q3b6ggnlnj (https://t.co/gEEhoNab5r)

Jan 2, 2020 · 1 like · 4,078 followers View post →
Hacker News 100
@newsyc100 · X

Quality of acute experience predicts therapeutic efficacy of psilocybin https://t.co/Gd8IIofLQt (https://t.co/iX8sRQG7qL)

Jan 2, 2020 · 9,230 followers View post →
Hn250
@Hn251 · X

Psilocybin found safe in largest ever controlled study https://t.co/QRSFLSUCXW (https://t.co/PCZL8221O4)

Jan 2, 2020 · 43 followers View post →
Hn150
@Hn150 · X

Psilocybin found safe in largest ever controlled study https://t.co/EVdf9VGtat (https://t.co/a8mExu8pcE)

Jan 2, 2020 · 104 followers View post →
Trisstina Tone
@itsMalma · X

@Terrenc43516485 @reubing I mean... I'm far from liking her but she does have a point. North America has a big prescription pill problem and micro-dosing of shrooms is extremely promising for treating things most consider almost untreatable. https://t.co/wrxhlosAoV https://t.co/I38KFt9MC7

Jun 9, 2019 · 1 like · 4,198 followers View post →
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org/10.3389/fphar.2017.00974 4. Nichols, D. E. (2016). Psychedelics. Pharmacological Reviews, 68(2), 264–355. https: //doi.org/10.1124/pr ...

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