Oncotarget February 2018 PMID 29515798

Metformin and berberine, two versatile drugs in treatment of common metabolic diseases.

Haoran Wang, Chen Zhu, Ying Ying, Lingyu Luo, Deqiang Huang, Zhijun Luo

Download social card

Mentions

97
Peak: 29 in May 2024
across 4 sources since May 2019

Extended reach

348,513
potential audience

Total likes

408

Video views

7,959

Mentions per month

May 2019 – Dec 2024

Where it's discussed

  • X / Twitter85 posts
  • News6 articles
  • Facebook4 posts
  • YouTube2 videos

AI synopsis

What people are saying

The collective discussions show a strong interest in comparing metformin and berberine, with many posts noting their similar effects on gut health and insulin sensitivity. The tone is inquisitive and analytical, reflecting both curiosity and recognition of potential therapeutic impacts, such as transforming berberine into a practical treatment despite bioavailability concerns.

AgreementModerate agreement

Most discussions highlight the potential benefits of both drugs, with several posts emphasizing their similarities and therapeutic possibilities, showing general agreement.

InterestHigh interest

The topic sparks strong curiosity, with multiple comments asking whether berberine could be as effective as metformin and referencing detailed biochemical effects.

EngagementModerate engagement

Several posters actively share information, ask questions, and discuss nuanced scientific effects, indicating a decent level of thoughtful engagement.

ImpactModerate impact

The discussions consider the practical implications for treatment and clinical practice, suggesting a moderate perceived impact of the research.

Top posts

Most liked on X and Bluesky
Rene Sugar
@renesugar · X

Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcTgoOh2 https://t.co/Q1nghSS1y9

May 25, 2024 · 129 likes · 32 shares · 3,970 followers View post →
Dr. Jay Wrigley
@hormonedietdoc · X

Metformin and berberine, two versatile drugs in the treatment of common metabolic diseases "Therefore, it is the right time to transform the beneficial effects of berberine into therapeutic practice." Think botanical medicines before synthetic drugs https://t.co/CFeakZuvKG

Aug 10, 2022 · 98 likes · 14 shares · 106,104 followers View post →
John Haughton MD, MS
@doc4care · X

@Mr_Inquisitr @chydorina Berberine shown to have similar effects as #metformin. Both increase gut short chain fatty acids. Both lower TLR4 activity. Both increase insulin sensitivity. They both move polarization from M1 (inflame and kill) macrophages to M2 (build). Link: https://t.co/nWmHFkyfMs

Jan 17, 2024 · 29 likes · 7 shares · 3,532 followers View post →
John Haughton MD, MS
@doc4care · X

Jul 4, 2024 · 27 likes · 13 shares · 3,532 followers View post →
Vinod Abichandani
@DrVinodEndo · X

@LoriShemek Wang, H., Zhu, C., Ying, Y., Luo, L., Huang, D., & Luo, Z. (2017). Metformin and berberine, two versatile drugs in treatment of common metabolic diseases. Oncotarget, 9(11), 10135–10146. https://t.co/0xcDU2euDv

Jan 17, 2023 · 9 likes · 4,639 followers View post →
KC
@takeitfromkate · X

@deNutrients @NeBirgitta @gutwat1 This is interesting. Wonder if Berberine could have the same effect? However, I have read that Berberine can cause depletion of gut flora/dysbiosis. Short term use maybe?

Apr 27, 2021 · 5 likes · 2 shares · 243 followers View post →

All mentions

Gary
@GaryBigbegisbro · X

@CepoiTudor @davidasinclair Try this https://t.co/XAomqNc3ih

Dec 3, 2024 · 2 likes · 75 followers View post →
Juan Penaloza
@J_P_28 · X

RT @doc4care:

Jul 12, 2024 · 13 shares · 1,746 followers View post →
N
@CFSnova · X

RT @doc4care:

Jul 9, 2024 · 13 shares · 534 followers View post →
GardenRebellion
@NobleRingleader · X

RT @doc4care:

Jul 5, 2024 · 13 shares · 643 followers View post →
oracling in the fucking apocalypse
@noralove · X

RT @doc4care:

Jul 5, 2024 · 13 shares · 2,748 followers View post →
RemissionBiome MECFS/LongCovid Patient-Led Science
@remissionbiome · X

RT @doc4care:

Jul 5, 2024 · 13 shares · 10,279 followers View post →
Johnny Galtar
@JohnnyGaltar · X

RT @doc4care:

Jul 4, 2024 · 13 shares · 435 followers View post →
Adam Van Bavel
@AdamVanBavel · X

RT @doc4care:

Jul 4, 2024 · 13 shares · 7,331 followers View post →
Asklepios Physis
@Asklepi87416874 · X

RT @doc4care:

Jul 4, 2024 · 13 shares · 19 followers View post →
Jürgen Sasse
@DeeJaySas · X

RT @doc4care:

Jul 4, 2024 · 13 shares · 897 followers View post →
Akane
@Akanegg3 · X

RT @doc4care:

Jul 4, 2024 · 13 shares · 233 followers View post →
P123
@P1231032850 · X

RT @doc4care:

Jul 4, 2024 · 13 shares · 3,386 followers View post →
Isabel Burnett | Renegade Research
@IsabelRamirezRD · X

RT @doc4care:

Jul 4, 2024 · 13 shares · 4,053 followers View post →
John Haughton MD, MS
@doc4care · X

Jul 4, 2024 · 27 likes · 13 shares · 3,532 followers View post →
Ex_Citizen_BuckTweet
@GuyGadboisGuyG1 · X

RT @DougMann7: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases https://t.co/QvKwSAruMy

Jun 8, 2024 · 1 share · 4,608 followers View post →
Doug Mann
@DougMann7 · X

Metformin and berberine, two versatile drugs in treatment of common metabolic diseases https://t.co/QvKwSAruMy

Jun 7, 2024 · 1 like · 1 share · 690 followers View post →
Ana Calber
@amcalber · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 27, 2024 · 32 shares · 2,264 followers View post →
Sven from Post-Covid-Plan.com
@PostCovidPlan · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 27, 2024 · 32 shares · 17 followers View post →
T14TT
@T14TT2 · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 27, 2024 · 32 shares · 283 followers View post →
Jürgen Sasse
@DeeJaySas · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 27, 2024 · 32 shares · 897 followers View post →
Serafina
@Serafina83837 · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 27, 2024 · 32 shares · 375 followers View post →
K3vin
@Tr_K3vin · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 27, 2024 · 32 shares · 1,128 followers View post →
Luis Del Carpio Orantes
@CarpioOrantes23 · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 27, 2024 · 32 shares · 1,860 followers View post →
D Moore
@aizuchi1 · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 26, 2024 · 32 shares · 228 followers View post →
Parenting Mishmash
@ParentMishmash · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 26, 2024 · 32 shares · 3,936 followers View post →
VictorG
@VictorG14tdc · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 26, 2024 · 32 shares · 560 followers View post →
T h o r e
@justthore · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 26, 2024 · 32 shares · 8,936 followers View post →
DysautonomiaME
@DysautonomiaME · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 26, 2024 · 32 shares · 178 followers View post →
Chillfrog - are you kidding me?
@DPhilvon · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 26, 2024 · 32 shares · 860 followers View post →
Euan Arnott
@Nucleocapsoid · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 26, 2024 · 32 shares · 977 followers View post →
Fitz_Eng
@Fitz_Eng · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 26, 2024 · 32 shares · 346 followers View post →
ValerieJay16
@ValerieJay16 · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 26, 2024 · 32 shares · 3,121 followers View post →
Lord Hiroshima Twinkie
@HRMbowplease · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 26, 2024 · 32 shares · 141 followers View post →
Colleen Griffith
@Griffith17431 · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 26, 2024 · 32 shares · 939 followers View post →
Dr Melanie
@MelanieWeckert · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 26, 2024 · 32 shares · 11,250 followers View post →
Ireko Fitness
@Irekofitness · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 26, 2024 · 32 shares · 14,946 followers View post →
htw
@heniek_htw · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 26, 2024 · 32 shares · 11,353 followers View post →
Paul Westcott
@Westypc · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 26, 2024 · 32 shares · 4 followers View post →
Billy Hanlon
@bhanlon15 · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 25, 2024 · 32 shares · 13,707 followers View post →
David Michaels
@davidmichaels · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 25, 2024 · 32 shares · 4,015 followers View post →
michael with the blue eyes
@teavangelize · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 25, 2024 · 32 shares · 1,895 followers View post →
Friesein
@Friesein · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 25, 2024 · 32 shares · 12,554 followers View post →
P123
@P1231032850 · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 25, 2024 · 32 shares · 3,386 followers View post →
Ex_Citizen_BuckTweet
@GuyGadboisGuyG1 · X

RT @renesugar: Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcT…

May 25, 2024 · 32 shares · 4,608 followers View post →
Rene Sugar
@renesugar · X

Metformin and berberine, two versatile drugs in treatment of common metabolic diseases #MECFS #LongCovid https://t.co/vNvcTgoOh2 https://t.co/Q1nghSS1y9

May 25, 2024 · 129 likes · 32 shares · 3,970 followers View post →
Al
@allison_S7 · X

RT @doc4care: @Mr_Inquisitr @chydorina Berberine shown to have similar effects as #metformin. Both increase gut short chain fatty acids. B…

Jan 26, 2024 · 7 shares · 37 followers View post →
Akane
@Akanegg3 · X

RT @doc4care: @Mr_Inquisitr @chydorina Berberine shown to have similar effects as #metformin. Both increase gut short chain fatty acids. B…

Jan 25, 2024 · 7 shares · 233 followers View post →
Martha-JD, MBA, PCC-
@mryoung151 · X

RT @doc4care: @Mr_Inquisitr @chydorina Berberine shown to have similar effects as #metformin. Both increase gut short chain fatty acids. B…

Jan 24, 2024 · 7 shares · 8,907 followers View post →
Lizzie
@LizzieKro · X

RT @doc4care: @Mr_Inquisitr @chydorina Berberine shown to have similar effects as #metformin. Both increase gut short chain fatty acids. B…

Jan 24, 2024 · 7 shares · 935 followers View post →
annatiscia
@annatiscia · X

If you can’t get metformin, please try Berberine if it works with your regimen! https://t.co/1Y9ExvEKGc

Jan 24, 2024 · 2 likes · 2,982 followers View post →
Molly Gordon
@shaboom · X

RT @doc4care: @Mr_Inquisitr @chydorina Berberine shown to have similar effects as #metformin. Both increase gut short chain fatty acids. B…

Jan 24, 2024 · 7 shares · 12,901 followers View post →
Natalie Nichols
@NatalieGNichols · X

RT @doc4care: @Mr_Inquisitr @chydorina Berberine shown to have similar effects as #metformin. Both increase gut short chain fatty acids. B…

Jan 17, 2024 · 7 shares · 4,619 followers View post →
Lorraine Johnson, JD/MBA
@lymepolicywonk · X

RT @doc4care: @Mr_Inquisitr @chydorina Berberine shown to have similar effects as #metformin. Both increase gut short chain fatty acids. B…

Jan 17, 2024 · 7 shares · 2,343 followers View post →
John Haughton MD, MS
@doc4care · X

@Mr_Inquisitr @chydorina Berberine shown to have similar effects as #metformin. Both increase gut short chain fatty acids. Both lower TLR4 activity. Both increase insulin sensitivity. They both move polarization from M1 (inflame and kill) macrophages to M2 (build). Link: https://t.co/nWmHFkyfMs

Jan 17, 2024 · 29 likes · 7 shares · 3,532 followers View post →
Deepank Rana
@deepankcrypto · X

@theliverdr Please Share your Opnion on this Metformin vs Berberine ? https://t.co/sT3Hf49kFn Metformin and berberine, two versatile drugs in treatment of common metabolic diseases

Dec 6, 2023 · 98 followers View post →
Gospoja
@VirginMary_HR · X

@radicbozo81 https://t.co/r2qOjBnpfB , evo berberine ne spada u službenu zapadnu medicinu a već je dobro istražen i iako efikasan, blagih je nuspojava.

Sep 16, 2023 · 79 followers View post →
Dr. Chris Meletis
@DrMeletis · X

Berberine vs. Metformin Nice Review Paper: https://t.co/jo2dBbFMIE Full Article: https://t.co/JjR77DLDug https://t.co/sCIFu4qyvX

Mar 18, 2023 · 514 followers View post →
Harvey Cottrell LCSW, MSW, MA. (He/Him)
@Hcottrell2 · X

https://t.co/EupOU8xUaL

Jan 17, 2023 · 100 followers View post →
Vinod Abichandani
@DrVinodEndo · X

@LoriShemek Wang, H., Zhu, C., Ying, Y., Luo, L., Huang, D., & Luo, Z. (2017). Metformin and berberine, two versatile drugs in treatment of common metabolic diseases. Oncotarget, 9(11), 10135–10146. https://t.co/0xcDU2euDv

Jan 17, 2023 · 9 likes · 4,639 followers View post →
Tautaton
@tautaton · X

Long Covid: Regarding the interesting effects of metformin, you may ask, whether berberine would also be effective. Metformin and berberine, two versatile drugs in treatment of common metabolic diseases: https://t.co/TzWuwRx3nB

Dec 26, 2022 · 2 likes · 92 followers View post →
Maria
@Mary_v_Martha · X

RT @hormonedietdoc: Metformin and berberine, two versatile drugs in the treatment of common metabolic diseases "Therefore, it is the right…

Oct 11, 2022 · 14 shares · 1,988 followers View post →
Rene Sugar
@renesugar · X

@intothewhale Metformin and berberine, two versatile drugs in treatment of common metabolic diseases https://t.co/vNvcTg7cSs "The low efficiency of berberine transport to blood is mostly accounted for by the poor oral bioavailability"

Aug 15, 2022 · 3,970 followers View post →
Sorbus1
@Sorbus111 · X

RT @hormonedietdoc: Metformin and berberine, two versatile drugs in the treatment of common metabolic diseases "Therefore, it is the right…

Aug 11, 2022 · 14 shares · 4 followers View post →
Timothy Agaid,RND
@mountaintomti · X

RT @hormonedietdoc: Metformin and berberine, two versatile drugs in the treatment of common metabolic diseases "Therefore, it is the right…

Aug 11, 2022 · 14 shares · 8 followers View post →
Jenn030303
@Jenn030303 · X

RT @hormonedietdoc: Metformin and berberine, two versatile drugs in the treatment of common metabolic diseases "Therefore, it is the right…

Aug 11, 2022 · 14 shares · 891 followers View post →
Success to Health
@successtohealth · X

RT @hormonedietdoc: Metformin and berberine, two versatile drugs in the treatment of common metabolic diseases "Therefore, it is the right…

Aug 11, 2022 · 14 shares · 2,953 followers View post →
Justin Ward
@JustinW05482353 · X

RT @hormonedietdoc: Metformin and berberine, two versatile drugs in the treatment of common metabolic diseases "Therefore, it is the right…

Aug 11, 2022 · 14 shares · 709 followers View post →
kragen
@karagen · X

RT @hormonedietdoc: Metformin and berberine, two versatile drugs in the treatment of common metabolic diseases "Therefore, it is the right…

Aug 10, 2022 · 14 shares · 187 followers View post →
bloodstone
@NaDelgLlo · X

RT @hormonedietdoc: Metformin and berberine, two versatile drugs in the treatment of common metabolic diseases "Therefore, it is the right…

Aug 10, 2022 · 14 shares · 60 followers View post →
Living Fit
@DrDwayneKoot · X

RT @hormonedietdoc: Metformin and berberine, two versatile drugs in the treatment of common metabolic diseases "Therefore, it is the right…

Aug 10, 2022 · 14 shares · 82 followers View post →
Keto-meatheals
@orangebobevil · X

RT @hormonedietdoc: Metformin and berberine, two versatile drugs in the treatment of common metabolic diseases "Therefore, it is the right…

Aug 10, 2022 · 14 shares · 1,743 followers View post →
Sharon
@scarl12tx · X

RT @hormonedietdoc: Metformin and berberine, two versatile drugs in the treatment of common metabolic diseases "Therefore, it is the right…

Aug 10, 2022 · 14 shares · 7,720 followers View post →
Ramona G
@RamonaGorasciuc · X

RT @hormonedietdoc: Metformin and berberine, two versatile drugs in the treatment of common metabolic diseases "Therefore, it is the right…

Aug 10, 2022 · 14 shares · 655 followers View post →
Alexander
@dertreiser · X

RT @hormonedietdoc: Metformin and berberine, two versatile drugs in the treatment of common metabolic diseases "Therefore, it is the right…

Aug 10, 2022 · 14 shares · 388 followers View post →
KareemWaheedRPH
@KareemWaheedRPH · X

RT @hormonedietdoc: Metformin and berberine, two versatile drugs in the treatment of common metabolic diseases "Therefore, it is the right…

Aug 10, 2022 · 14 shares · 585 followers View post →
Dr. Jay Wrigley
@hormonedietdoc · X

Metformin and berberine, two versatile drugs in the treatment of common metabolic diseases "Therefore, it is the right time to transform the beneficial effects of berberine into therapeutic practice." Think botanical medicines before synthetic drugs https://t.co/CFeakZuvKG

Aug 10, 2022 · 98 likes · 14 shares · 106,104 followers View post →
Impact Journals
@ImpactJrnls · X

RT @Oncotarget: #2021YearinReview: Join us daily as we count down the 10 most-viewed papers in 2021 on https://t.co/C99cdZ0S6O. #10: "Metf…

Jan 12, 2022 · 1 share · 401 followers View post →
Oncotarget
@Oncotarget · X

#2021YearinReview: Join us daily as we count down the 10 most-viewed papers in 2021 on https://t.co/C99cdZ0S6O. #10: "Metformin and berberine, two versatile drugs in treatment of common metabolic diseases" Read the full review: https://t.co/QXchAmVTY8 #metformin #berberine https://t.co/S5dIPvUGHJ

Jan 12, 2022 · 4 likes · 1 share · 3,203 followers View post →
Dr L Boominathan PhD
@DrLBoominathan · X

Metformin and berberine, two versatile drugs in the treatment of common metabolic diseases https://t.co/oYYkxmunh6 https://t.co/JdjHfEqoQQ https://t.co/TYZ62SxqfF

Dec 30, 2021 · 890 followers View post →
Mayke Briggs
@MaykeBriggs · X

Metformin and berberine, two versatile drugs in treatment of common metabolic diseases. ⁦@Parsifaler⁩ https://t.co/SprJ2vn3wC

Oct 15, 2021 · 611 followers View post →
J.B. Watson, Jr., Ph.D.
@GWashingtonInde · X

Metformin and berberine, two versatile drugs in treatment of common metabolic diseases https://t.co/UrBGzc4vTs

Aug 28, 2021 · 7,622 followers View post →
Dr Sufian Arshad
@DrSufCh · X

RT @takeitfromkate: @deNutrients @NeBirgitta @gutwat1 This is interesting. Wonder if Berberine could have the same effect? However, I have…

Apr 28, 2021 · 2 shares · 1,961 followers View post →
Birgitta Neher
@NeBirgitta · X

RT @takeitfromkate: @deNutrients @NeBirgitta @gutwat1 This is interesting. Wonder if Berberine could have the same effect? However, I have…

Apr 27, 2021 · 2 shares · 2,814 followers View post →
KC
@takeitfromkate · X

@deNutrients @NeBirgitta @gutwat1 This is interesting. Wonder if Berberine could have the same effect? However, I have read that Berberine can cause depletion of gut flora/dysbiosis. Short term use maybe?

Apr 27, 2021 · 5 likes · 2 shares · 243 followers View post →
catlitter100
@catlitter100 · X

Metformin and berberine, two versatile drugs in treatment of common metabolic diseases https://t.co/mZVzwWQCPB

May 18, 2019 · 63 followers View post →