J Transl Med March 2018 PMID 29523156

Low dose Naltrexone for induction of remission in inflammatory bowel disease patients.

Mitchell R K L Lie, Janine van der Giessen, Gwenny M Fuhler, Alison de Lima, Maikel P Peppelenbosch, Cokkie van der Ent, C Janneke van der Woude

Mentions

14
Peak: 3 in Feb 2023
across 5 sources since Jun 2019

Extended reach

222,857
potential audience

Total likes

8,286

Video views

190,400

Mentions per month

Jun 2019 – Nov 2024

Where it's discussed

  • X / Twitter8 posts
  • YouTube2 videos
  • Facebook2 posts
  • Instagram1 posts
  • Reddit1 posts

AI synopsis

What people are saying

Many discussions highlight the potential of LDN for IBD, referencing specific statistics such as 74.5% clinical improvement and 25.5% remission, which reflect positive reception. Others point out broader issues like drug repurposing and personal benefits, hinting at both clinical and societal impacts, with tone ranging from supportive to curious.

AgreementModerate agreement

Most discussions support the findings that LDN shows promise for IBD, with posts citing specific improvements like clinical remission and gut healing.

InterestModerate interest

There is a moderate level of interest, as some posts express personal benefits and curiosity, while others are more general or skeptical.

EngagementModerate engagement

Comments vary from brief mentions to detailed questions about mechanisms and clinical applications, indicating a moderate level of engagement.

ImpactModerate impact

The discussions suggest that the article could influence personal treatment choices and raise awareness about drug repurposing, implying a noticeable impact.

Abstract in brief

  • Low dose Naltrexone (LDN) helped about 75% of IBD patients experience clinical improvement, with 25% reaching remission, showing potential as an alternative treatment for those not responding to traditional therapies.
  • LDN appears to directly enhance the health of the gut lining by promoting wound healing and decreasing cellular stress in the intestinal epithelium, which may help restore barrier function.
  • The study suggests that LDN is a safe and effective option for difficult-to-treat IBD patients, addressing issues like mucosal stress and impaired healing that contribute to disease persistence.]

Top posts

Most liked on X and Bluesky
⌬
@MindOfIntra · X

Low-Dose Naltrexone studies: https://t.co/4fJ3BKcTf4 https://t.co/Wtc8nEHs2q https://t.co/ubCSNdnGhc https://t.co/9zsi4XdxrV https://t.co/AY5ytQfSFy https://t.co/kPcOpbyUYH

Feb 19, 2024 · 2 likes · 1,833 followers View post →
Vincent Everts
@vincente · X

Interesting! Repurposed drugs are cheap https://t.co/6TJG0bQkYD therefore are not used very much. I think this is a scandal. Repurposed drugs are common in medicine, aspirin, morphine, viagra and prednisolone for example. After drugs have been on th… https://t.co/3eGct7qqPK

Feb 9, 2023 · 17,103 followers View post →
DENTRO_MADRID
@CER_OF_AUT · X

RT @JayneLCrocker: LDN induced clinical improvement in 74.5%, remission in 25.5% of #IBD patients with improved wound healing of intestinal…

Nov 19, 2024 · 5 shares · 3,478 followers View post →
Alisontomyradioooo
@arisonsned · X

RT @Snapzu_Health: Low dose Naltrexone for induction of remission in inflammatory bowel disease patients https://t.co/sAWAQ1BOpX

Jun 16, 2019 · 1 share · 2,999 followers View post →
Finne.
@martinfinne · X

@StenHelmfrid Linné classified some species wrong. In biomed the biology is studied, not the billable code index (icd-10, icpc-2(b)). In "your" mind naltroxene helps drug addicts. Why is it used partly successful in pwme, fibro, ibs? https://t.co/jSDh36z06Z

Mar 24, 2024 · 2,203 followers View post →
Finne.
@martinfinne · X

@chydorina so, why does low dose naltrexone help in "classic psychological diseases" like ibs and fibro and me? I didn't read this paper, just part of it. Brainfog. I did however find it bcs i know things. BTW, somebody may update the me-pedia article on ldn. https://t.co/kmovxqDGrS

Mar 24, 2024 · 2,203 followers View post →

All mentions

DENTRO_MADRID
@CER_OF_AUT · X

RT @JayneLCrocker: LDN induced clinical improvement in 74.5%, remission in 25.5% of #IBD patients with improved wound healing of intestinal…

Nov 19, 2024 · 5 shares · 3,478 followers View post →
Finne.
@martinfinne · X

@StenHelmfrid Linné classified some species wrong. In biomed the biology is studied, not the billable code index (icd-10, icpc-2(b)). In "your" mind naltroxene helps drug addicts. Why is it used partly successful in pwme, fibro, ibs? https://t.co/jSDh36z06Z

Mar 24, 2024 · 2,203 followers View post →
Finne.
@martinfinne · X

@chydorina so, why does low dose naltrexone help in "classic psychological diseases" like ibs and fibro and me? I didn't read this paper, just part of it. Brainfog. I did however find it bcs i know things. BTW, somebody may update the me-pedia article on ldn. https://t.co/kmovxqDGrS

Mar 24, 2024 · 2,203 followers View post →
⌬
@MindOfIntra · X

Low-Dose Naltrexone studies: https://t.co/4fJ3BKcTf4 https://t.co/Wtc8nEHs2q https://t.co/ubCSNdnGhc https://t.co/9zsi4XdxrV https://t.co/AY5ytQfSFy https://t.co/kPcOpbyUYH

Feb 19, 2024 · 2 likes · 1,833 followers View post →
Lenore Norrgard
@LenoreNorrgard · X

@ninapaley I have autoimmunity and have benefited greatly from LDN, as discussed in this article. I also have benefited greatly from healing my gut with the GAPS diet. Both prescribed by my naturopath. https://t.co/e2FacHbf9k

Dec 8, 2023 · 424 followers View post →
Vincent Everts
@vincente · X

Interesting! Repurposed drugs are cheap https://t.co/6TJG0bQkYD therefore are not used very much. I think this is a scandal. Repurposed drugs are common in medicine, aspirin, morphine, viagra and prednisolone for example. After drugs have been on th… https://t.co/3eGct7qqPK

Feb 9, 2023 · 17,103 followers View post →
Alisontomyradioooo
@arisonsned · X

RT @Snapzu_Health: Low dose Naltrexone for induction of remission in inflammatory bowel disease patients https://t.co/sAWAQ1BOpX

Jun 16, 2019 · 1 share · 2,999 followers View post →
Snapzu Health News
@Snapzu_Health · X

Low dose Naltrexone for induction of remission in inflammatory bowel disease patients https://t.co/sAWAQ1BOpX

Jun 12, 2019 · 1 share · 2,161 followers View post →
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