J Am Coll Cardiol May 2018 PMID 29540327

Carvedilol for Prevention of Chemotherapy-Related Cardiotoxicity: The CECCY Trial.

Mônica Samuel Avila, Silvia Moreira Ayub-Ferreira, Mauro Rogerio de Barros Wanderley, Fatima das Dores Cruz, Sara Michelly Gonçalves Brandão, Vagner Oliveira Carvalho Rigaud, Marília Harumi Higuchi-Dos-Santos, Ludhmila Abrahão Hajjar, Roberto Kalil Filho, Paulo Marcelo Hoff, Marina Sahade, Marcela S M Ferrari, Romulo Leopoldo de Paula Costa, Max Senna Mano, Cecilia Beatriz Bittencourt Viana Cruz

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Mentions

Peak: 3 in Dec 2021

across 4 sources since May 2018

Extended reach

3,831

potential audience

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1,757

Mentions per month

May 2018 – Dec 2021

Where it's discussed

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AI synopsis

What people are saying

The overall tone reflects curiosity about the study, exemplified by comments like 'It will be interesting to compare this publication with CECCY Trial,' which highlight interest but lack detailed critique or strong opinions. The focus on comparisons and recognition of the study's topic suggests a cautious and evaluative engagement level without deep involvement or perceived high impact.

AgreementNeither agree nor disagree

The discussions show curiosity but do not strongly agree or disagree, mostly expressing interest in comparing the study with other research.

InterestModerate interest

Comments indicate a mild level of interest, primarily focusing on the publication's relevance and future comparisons rather than deep analysis.

EngagementNeutral engagement

Posts are brief and mainly acknowledge the publication, with minimal detailed discussion or critique, reflecting shallow engagement.

ImpactNeutral impact

The discussions recognize the publication's relevance but do not suggest it has immediate or transformative influence, indicating a neutral impact perception.

Abstract in brief

The CECCY trial tested whether carvedilol could prevent heart damage caused by anthracycline chemotherapy in breast cancer patients; the study found no significant difference in preventing LVEF reduction but observed lower troponin I levels and less diastolic dysfunction in the carvedilol group.
While carvedilol didn't reduce the early signs of heart impairment (LVEF decline), it was associated with improved markers indicating less ongoing heart injury and better diastolic function during chemotherapy.
Overall, this study suggests carvedilol may not prevent initial decreases in heart function but could offer some protection against subtle heart damage during chemotherapy treatment.

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All mentions

Key Cardiological Trials Impacting 2018 Outcomes

This video reviews the top 10 cardiology trials of 2018, highlighting significant studies including those on PCI strategies in cardiogenic shock and the effects of various treatments on cardiovascular outcomes. Discover…

CardioLearning · Jan 8, 2019 969 views

Cardioprotective Effects of Carvedilol During Chemotherapy

The CECCY trial investigated whether carvedilol can prevent heart damage caused by anthracycline chemotherapy in breast cancer patients. While it didn't prevent early declines in heart function, it was associated with…

CardioLearning · May 22, 2018 788 views

Roberto Lugo

@RobertoLG86MI · X

RT @OSUCardioOnc: @ehj_ed @ESC_Journals @escardio It will be interesting to compare this publication with CECCY Trial

Dec 28, 2021 · 2 shares · 55 followers View post →

Cardioonc Bot

@Cardioonc_bot · X

RT @OSUCardioOnc: @ehj_ed @ESC_Journals @escardio It will be interesting to compare this publication with CECCY Trial

Dec 28, 2021 · 2 shares · 771 followers View post →

R.R. Baliga, MD

@OSUCardioOnc · X

@ehj_ed @ESC_Journals @escardio It will be interesting to compare this publication with CECCY Trial

Dec 28, 2021 · 1 like · 2 shares · 1,179 followers View post →

Beta-BlockerPapers

@BetaAdr_papers · X

Carvedilol for Prevention of Chemotherapy-Related Cardiotoxicity: The CECCY Trial. https://t.co/778dAtP67U

Aug 7, 2019 · 58 followers View post →