Neurology April 2018 PMID 29540588

Midlife cardiovascular fitness and dementia: A 44-year longitudinal population study in women.

Helena Hörder, Lena Johansson, XinXin Guo, Gunnar Grimby, Silke Kern, Svante Östling, Ingmar Skoog

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Mentions

238
Peak: 8 in Jan 2022
across 6 sources since Aug 2019

Extended reach

183,940
potential audience

Total likes

139

Video views

4,953

Mentions per month

Aug 2019 – Aug 2025

Where it's discussed

  • News156 articles
  • Facebook46 posts
  • X / Twitter19 posts
  • Blogs11 articles
  • YouTube3 videos
  • Reddit3 posts

AI synopsis

What people are saying

These discussions reflect strong agreement and interest, with posters highlighting that high fitness delays dementia by about 10 years and noting the longitudinal nature of the study. The tone varies from supportive to cautious, considering genetic factors, with some emphasizing the potential for lifestyle changes while others acknowledge complexity. Overall, the tone conveys recognition of the study's significance and its influence on health discussions.

AgreementStrong agreement

Most posts support the findings, emphasizing that high midlife fitness is linked to delayed dementia onset.

InterestHigh interest

Discussions show high interest, with many sharing specific details such as the delay of nearly 10 years and emphasizing the importance of fitness for brain health.

EngagementHigh engagement

Posts reference study results, mention related factors like genetics, and discuss broader implications, indicating meaningful engagement.

ImpactModerate impact

While some acknowledge genetic factors, many see this research as highlighting the critical role of cardiovascular health, suggesting a moderate but noteworthy impact.

Abstract in brief

  • A 44-year study of women found that those with higher cardiovascular fitness in midlife had a significantly lower risk of developing dementia.
  • Women with high fitness delayed the onset of dementia by almost 10 years and increased the time before dementia appeared by 5 years compared to women with medium fitness levels.
  • While the study suggests a link between good midlife fitness and reduced dementia risk, it does not prove causation, and further research is needed to determine if improving fitness at certain life stages can actively prevent dementia.

Top posts

Most liked on X and Bluesky
Profe Claudio Nieto
@profeclaudioni1 · X

"una buena condición cardiovascular en la mediana edad se asoció con un menor riesgo de demencia posterior" Estudio realizado durante 44 años nada más y nada menos ! https://t.co/2oIc3rMZKL

Jan 11, 2022 · 16 likes · 7 shares · 13,995 followers View post →
Nick Carrigan
@piperdoc1 · X

@Paddy_Barrett Delay dementia by 10 yrs..https://t.co/DwCq9ogsQV

Aug 10, 2022 · 9 likes · 3 shares · 323 followers View post →
William Lagakos
@caloriesproper2 · X

"a high cardiovascular fitness in midlife was associated with a decreased risk of subsequent dementia" https://t.co/vb5YlHfdWO

Aug 24, 2025 · 6 likes · 3 shares · 2,751 followers View post →
Ted ⚡️ Naiman
@tednaiman · X

@AngryGenXLady @Andrew_The_PA @DikemanDave Unfortunately there are huge genetic factors and a lot of other contributing factors, so one could sadly still develop dementia.

May 19, 2023 · 1 like · 95,231 followers View post →
Allen Y. Tien MD MHS 田一彦
@allentien · X

#Exercise #BrainFunction High fitness delayed age at dementia onset by 9.5 years and time to dementia onset by 5 years compared to medium fitness. https://t.co/RFJF4FQ0rU #HealthScience #SharedFacts

Jan 7, 2024 · 44,437 followers View post →
Esteban de las Heras.
@Estebandelashg · X

RT @profeclaudioni1: "una buena condición cardiovascular en la mediana edad se asoció con un menor riesgo de demencia posterior" Estudio r…

Jan 11, 2022 · 7 shares · 7,208 followers View post →

All mentions

Jeffery Nutrition
@JefferyNutr · X

RT @caloriesproper2: "a high cardiovascular fitness in midlife was associated with a decreased risk of subsequent dementia" https://t.co/vb…

Aug 25, 2025 · 3 shares · 284 followers View post →
no
@nullbotto · X

RT @caloriesproper2: "a high cardiovascular fitness in midlife was associated with a decreased risk of subsequent dementia" https://t.co/vb…

Aug 24, 2025 · 3 shares · 385 followers View post →
William Lagakos
@caloriesproper2 · X

"a high cardiovascular fitness in midlife was associated with a decreased risk of subsequent dementia" https://t.co/vb5YlHfdWO

Aug 24, 2025 · 6 likes · 3 shares · 2,751 followers View post →
Greg Renfro
@grenfro1 · X

Midlife cardiovascular fitness and dementia | Neurology https://t.co/wcaa64jNk2

Mar 14, 2025 · 8 followers View post →
Jerónimo Donoso Villa
@JeroDonosoVilla · X

#AptitudCardiovascular y #demencia en la mediana edad: un estudio longitudinal de población de 44 años en mujeres (doi:10.1212/WNL.0000000000005290). #HabitosSaludables, #Salud, #ActividadFisica, #Nutricion, #Formacion, #PoliticasDeSalud, #ORIGENLAB, #HUELVA. https://t.co/Lgeg1Qpk3J

Feb 15, 2025 · 61 followers View post →
Allen Y. Tien MD MHS 田一彦
@allentien · X

#Exercise #BrainFunction High fitness delayed age at dementia onset by 9.5 years and time to dementia onset by 5 years compared to medium fitness. https://t.co/RFJF4FQ0rU #HealthScience #SharedFacts

Jan 7, 2024 · 44,437 followers View post →
Ted ⚡️ Naiman
@tednaiman · X

@AngryGenXLady @Andrew_The_PA @DikemanDave Unfortunately there are huge genetic factors and a lot of other contributing factors, so one could sadly still develop dementia.

May 19, 2023 · 1 like · 95,231 followers View post →
Fiona McLoughlin Healy
@fionamacky · X

RT @piperdoc1: @Paddy_Barrett Delay dementia by 10 yrs..https://t.co/DwCq9ogsQV

Aug 14, 2022 · 3 shares · 4,638 followers View post →
Linda
@wordfinga · X

RT @piperdoc1: @Paddy_Barrett Delay dementia by 10 yrs..https://t.co/DwCq9ogsQV

Aug 10, 2022 · 3 shares · 4,593 followers View post →
Nick Carrigan
@piperdoc1 · X

@Paddy_Barrett Delay dementia by 10 yrs..https://t.co/DwCq9ogsQV

Aug 10, 2022 · 9 likes · 3 shares · 323 followers View post →
Dra.aflous
@DraAflous · X

RT @profeclaudioni1: "una buena condición cardiovascular en la mediana edad se asoció con un menor riesgo de demencia posterior" Estudio r…

Jan 12, 2022 · 7 shares · 10 followers View post →
Oscar Andres
@OscarAndresMD · X

RT @profeclaudioni1: "una buena condición cardiovascular en la mediana edad se asoció con un menor riesgo de demencia posterior" Estudio r…

Jan 11, 2022 · 7 shares · 548 followers View post →
Carla Pajeote
@querri_caverga · X

RT @profeclaudioni1: "una buena condición cardiovascular en la mediana edad se asoció con un menor riesgo de demencia posterior" Estudio r…

Jan 11, 2022 · 7 shares · 12 followers View post →
GYMHOUSEMOTIVATION
@7777Abadon · X

RT @profeclaudioni1: "una buena condición cardiovascular en la mediana edad se asoció con un menor riesgo de demencia posterior" Estudio r…

Jan 11, 2022 · 7 shares · 6 followers View post →
Esteban de las Heras.
@Estebandelashg · X

RT @profeclaudioni1: "una buena condición cardiovascular en la mediana edad se asoció con un menor riesgo de demencia posterior" Estudio r…

Jan 11, 2022 · 7 shares · 7,208 followers View post →
Adriakin ✝️
@RastyKiba · X

RT @profeclaudioni1: "una buena condición cardiovascular en la mediana edad se asoció con un menor riesgo de demencia posterior" Estudio r…

Jan 11, 2022 · 7 shares · 423 followers View post →
Daniel Moreno
@dmorenoost · X

RT @profeclaudioni1: "una buena condición cardiovascular en la mediana edad se asoció con un menor riesgo de demencia posterior" Estudio r…

Jan 11, 2022 · 7 shares · 642 followers View post →
Profe Claudio Nieto
@profeclaudioni1 · X

"una buena condición cardiovascular en la mediana edad se asoció con un menor riesgo de demencia posterior" Estudio realizado durante 44 años nada más y nada menos ! https://t.co/2oIc3rMZKL

Jan 11, 2022 · 16 likes · 7 shares · 13,995 followers View post →
Internet Medical
@_medjournal · X

Midlife cardiovascular fitness and dementia: A 44-year longitudinal population study in… https://t.co/OW4xBFF308

Aug 9, 2019 · 3,284 followers View post →