PLoS Med March 2018 PMID 29590099

Polycystic ovary syndrome, androgen excess, and the risk of nonalcoholic fatty liver disease in women: A longitudinal study based on a United Kingdom primary care database.

Balachandran Kumarendran, Michael W O'Reilly, Konstantinos N Manolopoulos, Konstantinos A Toulis, Krishna M Gokhale, Alice J Sitch, Chandrika N Wijeyaratne, Arri Coomarasamy, Wiebke Arlt, Krishnarajah Nirantharakumar

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Mentions

28
Peak: 5 in Oct 2020
across 5 sources since Oct 2020

Extended reach

341,719
potential audience

Total likes

5,514

Video views

322,916

Mentions per month

Oct 2020 – Apr 2025

Where it's discussed

  • X / Twitter11 posts
  • News11 articles
  • YouTube2 videos
  • Facebook2 posts
  • Blogs2 articles

AI synopsis

What people are saying

Overall, the discussions express strong agreement with the study's implications, as seen in comments about increased risks of diabetes and fatty liver in women with PCOS. They also demonstrate active engagement through examples of related health issues and mentions of upcoming panels, showing interest and awareness of the research's relevance.

AgreementModerate agreement

The discussions consistently acknowledge the link between PCOS, androgen excess, and metabolic risks, showing general support for the article's findings.

InterestHigh interest

Posts highlight a high level of curiosity and concern for health risks like diabetes and fatty liver disease associated with PCOS.

EngagementModerate engagement

Many comments reference existing research, mention upcoming discussions, and cite specific conditions, indicating active engagement.

ImpactModerate impact

The emphasis on health risks and calls for awareness suggest the publication could influence public understanding and clinical considerations.

Abstract in brief

  • This study shows that women with polycystic ovary syndrome (PCOS), especially those with higher levels of androgens like testosterone and sex hormone-binding globulin (SHBG), are at a greater risk of developing nonalcoholic fatty liver disease (NAFLD).
  • The research used a large UK primary care database to track over 63,000 women with PCOS and compared them to women without PCOS, finding that PCOS increases the likelihood of NAFLD even after accounting for factors like BMI and blood sugar levels.
  • Limitations of the study include its retrospective design, lack of detailed diagnostic criteria, and no information on laboratory methods used to measure androgen levels, but overall, it suggests that androgen excess in women with PCOS may contribute to liver disease risk.]

Top posts

Most liked on X and Bluesky
DAISy-PCOS
@DaisyPcos · X

Did you know those with #PCOS have an increased risk of #type2 #diabetes? (see https://t.co/Qk5AjvDc6j). Join @DAISyPCOS lead @WiebkeArlt & other @IMSR_UoB researchers for a special #WorldDiabetesDay panel discussion, tomorrow at 11am GMT. Register here: https://t.co/7goDctBJc9

Nov 13, 2020 · 8 likes · 4 shares · 1,116 followers View post →
DAISy-PCOS
@DaisyPcos · X

Women with #PCOS have an increased risk of #type2 #diabetes, #hypertension & #fattyliverdisease and these risks increase with increasing severity of androgen excess (see https://t.co/Qk5AjvDc6j). What about cardiovascular disease in PCOS? 4/13

Oct 1, 2020 · 4 likes · 4 shares · 1,116 followers View post →
Karl Storbeck
@KarlStorbeck · X

5/7 This is of concern in women, where elevated androgen levels are linked to increased risk of metabolic dysfunction as shown here in a study by @MickOReilly1980 @WiebkeArlt @Nirantharakumar https://t.co/yJzYNh8AiV & https://t.co/t9S23o7fpM https://t.co/2pLEcJVVbj

Apr 2, 2024 · 4 likes · 257 followers View post →
Verity (PCOS UK)
@veritypcos · X

RT @DaisyPcos: Did you know those with #PCOS have an increased risk of #type2 #diabetes? (see https://t.co/Qk5AjvDc6j). Join @DAISyPCOS lea…

Nov 13, 2020 · 4 shares · 6,020 followers View post →
Fibroid Network UK
@fibroidsupport · X

RT @DaisyPcos: Women with #PCOS have an increased risk of #type2 #diabetes, #hypertension & #fattyliverdisease and these risks increase wit…

Oct 9, 2020 · 4 shares · 3,449 followers View post →
Punith Kempegowda
@drpunith · X

RT @DaisyPcos: Women with #PCOS have an increased risk of #type2 #diabetes, #hypertension & #fattyliverdisease and these risks increase wit…

Oct 1, 2020 · 4 shares · 2,275 followers View post →

All mentions

Karl Storbeck
@KarlStorbeck · X

5/7 This is of concern in women, where elevated androgen levels are linked to increased risk of metabolic dysfunction as shown here in a study by @MickOReilly1980 @WiebkeArlt @Nirantharakumar https://t.co/yJzYNh8AiV & https://t.co/t9S23o7fpM https://t.co/2pLEcJVVbj

Apr 2, 2024 · 4 likes · 257 followers View post →
Emma Robinson (Collier)
@JemimaJane07 · X

RT @DaisyPcos: Did you know those with #PCOS have an increased risk of #type2 #diabetes? (see https://t.co/Qk5AjvDc6j). Join @DAISyPCOS lea…

Nov 14, 2020 · 4 shares · 310 followers View post →
West Midlands Physicians Association
@WMPA_UK · X

RT @DaisyPcos: Did you know those with #PCOS have an increased risk of #type2 #diabetes? (see https://t.co/Qk5AjvDc6j). Join @DAISyPCOS lea…

Nov 14, 2020 · 4 shares · 442 followers View post →
Verity (PCOS UK)
@veritypcos · X

RT @DaisyPcos: Did you know those with #PCOS have an increased risk of #type2 #diabetes? (see https://t.co/Qk5AjvDc6j). Join @DAISyPCOS lea…

Nov 13, 2020 · 4 shares · 6,020 followers View post →
Caroline Gillett
@cdtgillett · X

RT @DaisyPcos: Did you know those with #PCOS have an increased risk of #type2 #diabetes? (see https://t.co/Qk5AjvDc6j). Join @DAISyPCOS lea…

Nov 13, 2020 · 4 shares · 1,093 followers View post →
DAISy-PCOS
@DaisyPcos · X

Did you know those with #PCOS have an increased risk of #type2 #diabetes? (see https://t.co/Qk5AjvDc6j). Join @DAISyPCOS lead @WiebkeArlt & other @IMSR_UoB researchers for a special #WorldDiabetesDay panel discussion, tomorrow at 11am GMT. Register here: https://t.co/7goDctBJc9

Nov 13, 2020 · 8 likes · 4 shares · 1,116 followers View post →
Fibroid Network UK
@fibroidsupport · X

RT @DaisyPcos: Women with #PCOS have an increased risk of #type2 #diabetes, #hypertension & #fattyliverdisease and these risks increase wit…

Oct 9, 2020 · 4 shares · 3,449 followers View post →
Hormone Equilibrium
@HormoneEquilib · X

RT @DaisyPcos: Women with #PCOS have an increased risk of #type2 #diabetes, #hypertension & #fattyliverdisease and these risks increase wit…

Oct 1, 2020 · 4 shares · 1,883 followers View post →
Sharon Newson
@BigPictureLivin · X

RT @DaisyPcos: Women with #PCOS have an increased risk of #type2 #diabetes, #hypertension & #fattyliverdisease and these risks increase wit…

Oct 1, 2020 · 4 shares · 763 followers View post →
Punith Kempegowda
@drpunith · X

RT @DaisyPcos: Women with #PCOS have an increased risk of #type2 #diabetes, #hypertension & #fattyliverdisease and these risks increase wit…

Oct 1, 2020 · 4 shares · 2,275 followers View post →
DAISy-PCOS
@DaisyPcos · X

Women with #PCOS have an increased risk of #type2 #diabetes, #hypertension & #fattyliverdisease and these risks increase with increasing severity of androgen excess (see https://t.co/Qk5AjvDc6j). What about cardiovascular disease in PCOS? 4/13

Oct 1, 2020 · 4 likes · 4 shares · 1,116 followers View post →