PubHawk
March 2018 PMID 29599478

Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD in healthy middle-aged and older adults.

Christopher R Martens, Blair A Denman, Melissa R Mazzo, Michael L Armstrong, Nichole Reisdorph, Matthew B McQueen, Michel Chonchol, Douglas R Seals

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Mentions

220
Peak: 4 in Sep 2025
across 6 sources since Jan 2019

Extended reach

72,941
potential audience

Total likes

628

Video views

12,248

Mentions per month

Jan 2019 – Sep 2025

Where it's discussed

  • News166 articles
  • Blogs16 articles
  • X / Twitter14 posts
  • Facebook12 posts
  • YouTube7 videos
  • Reddit5 posts

AI synopsis

What people are saying

The discussions reflect a generally positive reception with expressions like 'This study seems interesting' and sharing the safety and elevated NAD+ levels, indicating mild curiosity and recognition of potential benefits. The tone is informative yet somewhat cautious, aligning with moderate agreement and engagement levels.

AgreementModerate agreement

Most discussions acknowledge the positive findings regarding safety and NAD level increases, indicating general agreement with the study's conclusions.

InterestModerate interest

Participants show moderate interest, with some stating they find the study 'interesting' or sharing curiosity about its implications.

EngagementModerate engagement

The level of engagement is moderate, with few posts discussing specific mechanisms, potential applications, or raising questions about the study's broader significance.

ImpactNeutral impact

The discussions suggest that the publication may influence ongoing research or personal health considerations but without strong evidence of immediate widespread impact.

Abstract in brief

  • Chronic nicotinamide riboside (NR) supplementation is safe and increases NAD levels in healthy middle-aged and older adults.
  • The study found that taking NR for 26 weeks effectively boosts NAD metabolism and is well tolerated.
  • Initial findings suggest that NR may help improve blood pressure and arterial stiffness, indicating potential cardiovascular benefits worth further investigation.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Rene Sugar
@renesugar · X

Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults https://t.co/bRXiJ6gS69

Feb 27, 2023 · 3 likes · 3,953 followers View post →
Andreas
@munchnygaard · X

Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD + in healthy middle-aged and older adults | Nature Communications #NR #NAD https://t.co/NvOBubMeGU

Nov 22, 2019 · 2 likes · 81 followers View post →
Aubrai
@Aubrai_ · X

@DagobertIX @CharlesMBrenner

Sep 19, 2025 · 1 like · 10,809 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults https://t.co/L6vhUC7agX

Apr 23, 2019 · 1 like · 2,240 followers View post →
Sugarmedown
@Sugarmedown · X

Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults https://t.co/et9RHIBRaI

Jun 24, 2021 · 1 like · 2,102 followers View post →
jordi de Haro
@zazen71 · X

@dougkalmanphdrd This study seems interesting This study seems interesting https://t.co/WbskxujIvp

Jun 28, 2020 · 1 like · 626 followers View post →

All mentions

Aubrai
@Aubrai_ · X

@DagobertIX @CharlesMBrenner

Sep 19, 2025 · 1 like · 10,809 followers View post →
Aubrai
@Aubrai_ · X

@ZhA3Izqp7J4hSCd @BioProtocol

Sep 18, 2025 · 10,809 followers View post →
Aubrai
@Aubrai_ · X

@yildirimesad @BioProtocol

Sep 16, 2025 · 10,809 followers View post →
Alex Leaf
@AlexJLeaf · X

@CharlesMBrenner Can you share? Here's a list of interventions showing it has little to no effect on clinical outcomes. https://t.co/IkTJUGcoTG https://t.co/gzFz1pNl4q https://t.co/ppApaZv2bA https://t.co/KD1y3lEM8h https://t.co/SRgr0bbZpK https://t.co/0ypM5uozRV https://t.co/HQo8SNxJN7

Jun 7, 2023 · 3,933 followers View post →
Rene Sugar
@renesugar · X

Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults https://t.co/bRXiJ6gS69

Feb 27, 2023 · 3 likes · 3,953 followers View post →
Sugarmedown
@Sugarmedown · X

Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults https://t.co/et9RHIBRaI

Jun 24, 2021 · 1 like · 2,102 followers View post →
Matthew McCombs
@mkmccombs · X

Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults https://t.co/mD754ht9Cw

Aug 16, 2020 · 39 followers View post →
jordi de Haro
@zazen71 · X

@dougkalmanphdrd This study seems interesting This study seems interesting https://t.co/WbskxujIvp

Jun 28, 2020 · 1 like · 626 followers View post →
Techno Rabbi
@CachedTweet · X

Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD + in healthy middle-aged and older adults | Nature Communications #AntiAging #LifeSpan https://t.co/LzEwcerRdd

Feb 2, 2020 · 166 followers View post →
Andreas
@munchnygaard · X

Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD + in healthy middle-aged and older adults | Nature Communications #NR #NAD https://t.co/NvOBubMeGU

Nov 22, 2019 · 2 likes · 81 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults https://t.co/6QyQsGePN2

Apr 26, 2019 · 2,240 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults https://t.co/L6vhUC7agX

Apr 23, 2019 · 1 like · 2,240 followers View post →
Stephen Pimentel
@StephenPiment · X

Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults https://t.co/AxeFcYLOza

Jan 10, 2019 · 12,650 followers View post →
Georgmer
@georg707 · X

elkezdtem szedni talán nem hülyülök meg idő előtt :D Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD + in healthy middle-aged and… https://t.co/wI3kmA8XwQ

Jan 4, 2019 · 238 followers View post →